Effect of Long Working Hours on Cardiovascular Disease in South Korean Workers: A Longitudinal Study

2020 ◽  
pp. 101053952097992
Author(s):  
Soojung Kim ◽  
Youn Jung
Keyword(s):  
Longitudinal Study ◽  
Working Hours ◽  
Multivariable Logistic Regression Analysis ◽  
Long Working Hours ◽  
South Korean ◽  
Cox Proportional Hazard ◽  
A Prospective Study ◽  
Prospective Study Design ◽  
The Relationship

This study aimed to examine the association between working hours and onset of cardiovascular diseases (CVDs) using a prospective study design. We used the Korean Longitudinal Study of Aging (KLoSA) data from 2006 to 2016. A total of 2405 workers who were working 35 hours or more per week and who did not have CVD at baseline were analyzed. Cox proportional hazard model was used for the analysis to determine the association between working hours per week at baseline and the new onset of CVD. In addition, multivariable logistic regression analysis was used to test the relationship between average working hours throughout the entire follow-up period and the risk of CVD (N = 1134). Working above 52 hours per week at baseline was related to higher risk of CVD than working between 35 and 40 hours a week (hazard ratio [HR] = 2.08, 95% confidence interval [CI] = 1.60-2.70 for 52-60 hours; HR = 1.38, 95% CI = 1.05-1.81 for >60 hours). A worker’s average working hours throughout the following period were also significantly associated with elevated risks of CVD (odds ratio = 4.40, 95% CI = 1.58-12.22 for >60 hours). The findings underline the need for more proactive interventions to protect the health of workers exposed to long working hours.

The Impact of Long Working Hours on Cognitive Function: A Follow-Up Study with Gender Stratification

2021 ◽  
Vol 80 (2) ◽  
pp. 727-734
Author(s):  
Seunghyun Lee ◽  
Joon Yul Choi ◽  
Wanhyung Lee
Keyword(s):  
Cognitive Function ◽  
Cognitive Decline ◽  
Working Hours ◽  
Gender Stratification ◽  
Long Working Hours ◽  
Cox Proportional Hazard ◽  
Hazard Ratios ◽  
Cox Proportional Hazard Regression ◽  
The Impact ◽  
The Relationship

Background: Recent studies have shown that long working hours can have adverse consequences on health and possibly trigger biological processes that mediate the relationship between long working hours and cognitive decline. Objective: To investigate whether long working hours and the overall duration such exposure is associated with a decline in cognitive function. Methods: Data obtained during the Korean Longitudinal Study on Aging (n = 2,518) during the period 2006–2018 were used to explore the relationship between long working hours and cognitive decline. Korean version of the Mini-Mental State Examination (K-MMSE) scores were used to evaluate cognitive function. Cox proportional hazard regression models were used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs), which were used to evaluate declines in K-MMSE scores over the 12-year study period. Results: Overall HR (95% CI) for a decline in cognitive function in long working hours group was 1.13 (0.73–1.17). When categorized by sex, women with long working hours had an HR (95% CI) of 1.50 (1.05–2.22), K-MMSE scores decreased significantly after working long hours for 5 years (p < 0.01). Conclusion: The study furthers understanding of the effects of long working hours on cognitive decline among female workers. Further research is required to determine the effects of long working hours on cognitive functions.

THE PRESENCE OF MULTIPLE MICROBLEEDS AS A PREDICTOR OF SUBSEQUENT CEREBRAL HEMORRHAGE IN PATIENTS WITH MOYAMOYA DISEASE

Neurosurgery ◽  
2008 ◽  
Vol 62 (1) ◽  
pp. 104-112 ◽  
Author(s):  
Ken-ichiro Kikuta ◽  
Yasushi Takagi ◽  
Kazuhiko Nozaki ◽  
Nobukatsu Sawamoto ◽  
Hidenao Fukuyama ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Moyamoya Disease ◽  
Magnetic Resonance Study ◽  
Cox Proportional Hazard ◽  
Kaplan Meier ◽  
Number Of Patients ◽  
Group A ◽  
A Prospective Study ◽  
The Relationship

Abstract OBJECTIVE To examine the relationship between asymptomatic microbleeds (MBs) and the occurrence of subsequent stroke in patients with moyamoya disease. METHODS Beginning in October 2003, 50 consecutive patients with moyamoya disease were enrolled in a prospective study using 3-T magnetic resonance imaging. These patients were followed from the date of the initial magnetic resonance study until the date of the first subsequent stroke or final magnetic resonance study. The median follow-up period was 15 months. The patients were comprised of 13 men and 37 women ranging in age from 9 to 68 years (mean age, 40.5 ± 16.2 yr). RESULTS Although no MBs were found in 27 patients in the initial magnetic resonance study, a total of 66 MBs were found in the remaining 23 patients. Eleven patients had a single MB and 12 had multiple MBs. The patients were divided into three groups according to the number of MBs: a non-MB group, a single-MB group, and a multi-MB group. Kaplan-Meier curves of the three groups showed a significantly higher likelihood of subsequent hemorrhage in the multi-MB group than in either the non-MB or single-MB groups (P = 0.0380). No significant differences among the three groups were seen in terms of their subsequent infarction-free ratios. Age-adjusted analysis performed with the Cox proportional hazard model also showed the presence of multiple MBs as an independent risk factor (hazard ratio, 2.89; 95% confidence interval, 1.001–13.24). CONCLUSION The presence of multiple MBs might be a predictor of subsequent hemorrhage in patients with moyamoya disease. Confirmation of these results will require a study with a larger number of patients and a longer follow-up period.

scholarly journals Oncological evaluation in the perioperative period using cfDNA with BRAF V600E mutation in patients with colorectal cancer

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Keita Tanaka ◽  
Yoichiro Yoshida ◽  
Teppei Yamada ◽  
Takaomi Hayashi ◽  
Hideki Shimaoka ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Perioperative Period ◽  
Radical Resection ◽  
Braf V600e ◽  
Tumor Diameter ◽  
Prognostic Information ◽  
A Prospective Study ◽  
Digital Polymerase Chain Reaction ◽  
The Relationship

AbstractThe detection of circulating cell-free DNA (cfDNA) by liquid biopsy is reported to provide prognostic information in colorectal cancer (CRC). Although the frequency of BRAF V600E mutation in CRC is less than 10%, it is associated with poor responses to conventional chemotherapy. We conducted a prospective study to investigate the relationship between the perioperative mutant allele frequency (MAF) of BRAF V600E and tumor recurrence, and to evaluate the possibility of early detection of recurrence. Among 362 patients who underwent radical resection, cfDNA was extracted from the perioperative blood of 11 CRC patients with BRAF V600E mutation and analyzed using the digital polymerase chain reaction (dPCR) system. The median follow-up time was 22 months, and there were four cases of recurrence. Although there was no correlation between recurrence and the perioperative MAF of BRAF V600E, tumor diameter was correlated with the MAF (p = 0.024), and the MAF increased with time in two patients from whom additional samples were obtained prior to recurrence. In this study, we identified a correlation between the pathological tumor diameter and the MAF, but it was difficult to predict recurrence by measuring cfDNA with BRAF V600E mutation in the perioperative period of radical resection of CRC.

scholarly journals The Relationship between Long Working Hours and Industrial Accident

2014 ◽  
Vol 23 (1) ◽  
pp. 39-46 ◽  
Author(s):  
Ju-Young Lee ◽  
Eunhi Choi ◽  
Sung-Ho Lim ◽  
Hyoung-Ah Kim ◽  
Hye-Sun Jung
Keyword(s):  
Working Hours ◽  
Industrial Accident ◽  
Long Working Hours ◽  
The Relationship

scholarly journals Shift work, long working hours, and later risk of dementia: A long-term follow-up of the Copenhagen Male Study

2017 ◽  
Author(s):  
Kirsten Nabe-Nielsen ◽  
Anne Helene Garde ◽  
Kazi Ishtiak-Ahmed ◽  
Finn Gyntelberg ◽  
Erik Lykke Mortensen ◽  
...  
Keyword(s):  
Shift Work ◽  
Working Hours ◽  
Long Working Hours ◽  
Long Term Follow Up

Factors Associated with Pathological Dissociation in the General Population

2005 ◽  
Vol 39 (5) ◽  
pp. 387-394 ◽  
Author(s):  
Päivi Maaranen ◽  
Antti Tanskanen ◽  
Kirsi Honkalampi ◽  
Kaisa Haatainen ◽  
Jukka Hintikka ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
General Population ◽  
Prospective Study ◽  
Population Sample ◽  
Dissociative Experiences Scale ◽  
Factors Associated ◽  
Dissociative Experiences ◽  
A Prospective Study ◽  
Prospective Study Design ◽  
The Relationship

Objective: This study assessed the prevalence of pathological dissociation in the general population, and the relationship between pathological dissociation and sociodemographic and several psychiatric variables. Method: The stratified population sample consisted of 2001 subjects. The study questionnaires included the Dissociative Experiences Scale, the Dissociative Experiences Scale-Taxon, the Toronto Alexithymia Scale, the Beck Depression Inventory, and sociodemographic background. Results: The prevalence of pathological dissociation (DES-T ≥ 20) was 3.4% in the general population and did not differ significantly between genders. Men scored higher than women in the amnesia subscale, and women in the absorption and imaginative involvement subscale. The relationship between pathological dissociation, alexithymia, depression and suicidality was strong. The likelihood of pathological dissociation was nearly nine-fold higher among depressive subjects, more than seven-fold higher among alexithymic subjects, and more than four-fold higher among suicidal subjects than among the others. Frequent alcohol consumption also associated significantly with pathological dissociation. Conclusions: A significant relationship between pathological dissociation, depression, alexithymia, and suicidality was found in the general population. The importance of these factors should be examined in a prospective study design to determine causality.

scholarly journals Associations between working environment and weight control efforts among workers with obesity in Korea

2018 ◽  
Vol 46 (6) ◽  
pp. 2307-2316 ◽  
Author(s):  
Hye Sun Hyun ◽  
Yunyoung Kim
Keyword(s):  
Working Conditions ◽  
Weight Control ◽  
Workplace Health Promotion ◽  
Working Hours ◽  
Working Environment ◽  
Multivariable Logistic Regression Analysis ◽  
Personal Factors ◽  
Regular Employment ◽  
Individual Variables ◽  
The Relationship

Objective The aim of this study was to investigate the relationship between working environment and weight control efforts among obese workers in Korea. Methods This study was based on the 2011 3rd Korean Working Conditions Survey, which was conducted on workers aged 15 years or older. A sample of 484 obese workers was included in the study. Multivariable logistic regression analysis was used to investigate the relationship between working environment and weight control efforts after controlling for individual variables. Adjusted odds ratios (ORs) and 95% confidence intervals were calculated. Results Of the participants, 63.4% reported that they made efforts to control their weight. After controlling for personal factors, the OR of weight control efforts for individuals working 40–49 hours per week was 2.4 times that for individuals working 60 hours or more per week. The OR of regular employment workers was 2.2 times that of non-regular workers. Conclusion We established that working hours and employment type were significantly related to weight control efforts. Therefore, we recommend that working conditions should be considered in designing effective workplace health promotion programs.

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