Parent- and child-reported anxiety disorders differentiating major depressive disorder and dysthymic disorder in children and adolescents

2020 ◽  
pp. 103985622096036
Author(s):  
Alasdair Vance ◽  
Jo Winther
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Anxiety Disorders ◽  
Children And Adolescents ◽  
Early Recognition ◽  
Cross Sectional Study ◽  
Dysthymic Disorder ◽  
Post Traumatic Stress ◽  
Major Depressive ◽  
Cross Sectional

Objective: To date, specific parent- and child-defined anxiety disorders associated with dysthymic disorder (DD; DSM-5 persistent depressive disorder equivalent) with and without major depressive disorder (MDD) have not been investigated in children and adolescents. Method: In a cross-sectional study, we compared point prevalence rates of parent- and child-reported anxiety disorders in DD alone ( N = 154), MDD alone ( N = 29), comorbid DD and MDD ( N = 130) and anxiety disorders alone ( N = 126) groups. Results: DD alone and MDD alone did not differ with respect to comorbid anxiety disorders from parent and child reports, while parent-reported panic disorder (PD) was significantly increased in the DD and MDD group compared to the other three groups as was child-reported post-traumatic stress disorder (PTSD) compared to the MDD alone and anxiety disorders alone groups. In contrast, specific phobia (SpPh) was significantly increased in the anxiety disorders alone group compared to the DD and MDD group. Conclusion: The findings suggest that specific fear-related anxiety disorders, especially parent-reported PD and child-reported PTSD, may aid the early recognition of DD and MDD.

scholarly journals Major depression subtypes are differentially associated with migraine subtype, prevalence and severity

Cephalalgia ◽  
2019 ◽  
Vol 40 (4) ◽  
pp. 347-356 ◽  
Author(s):  
Claudia Pisanu ◽  
Emma Lundin ◽  
Martin Preisig ◽  
Mehdi Gholam-Rezaee ◽  
Enrique Castelao ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Migraine With Aura ◽  
Migraine Without Aura ◽  
Population Based ◽  
Cross Sectional Study ◽  
High Rate ◽  
Major Depressive ◽  
Cross Sectional ◽  
Depression Subtypes

Objective Migraine and major depressive disorder show a high rate of comorbidity, but little is known about the associations between the subtypes of major depressive disorder and migraine. In this cross-sectional study we aimed at investigating a) the lifetime associations between the atypical, melancholic, combined and unspecified subtype of major depressive disorder and migraine with and without aura and b) the associations between major depressive disorder and its subtypes and the severity of migraine. Methods A total of 446 subjects with migraine (migraine without aura: n = 294; migraine with aura: n = 152) and 2511 controls from the population-based CoLaus/PsyCoLaus study, Switzerland, were included. Associations between major depressive disorder subtypes and migraine characteristics were tested using binary logistic or linear regression. Results Melancholic, combined and unspecified major depressive disorder were associated with increased frequency of migraine with aura, whereas only melancholic major depressive disorder was associated with increased frequency of migraine without aura. Lifetime and unspecified major depressive disorder were associated with severe migraine intensity among subjects with migraine with aura but not migraine without aura, while combined major depressive disorder was associated with higher migraine frequency independently from migraine subtype. Conclusion This study suggests that melancholic but not atypical major depressive disorder is associated with migraine and migraine subtypes. Future studies exploring pathophysiological mechanisms shared between melancholic depression and migraine are warranted.

Investigation of associations between recurrence of major depressive disorder and spinal posture alignment: A quantitative cross-sectional study

2017 ◽  
Vol 52 ◽  
pp. 258-264 ◽  
Author(s):  
Janette Z. Canales ◽  
Juliana T. Fiquer ◽  
Rodolfo N. Campos ◽  
Márcio Gerhardt Soeiro-de-Souza ◽  
Ricardo Alberto Moreno
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Major Depressive ◽  
Cross Sectional ◽  
Spinal Posture

White matter fiber microstructure is associated with prior hospitalizations rather than acute symptomatology in major depressive disorder

2020 ◽  
pp. 1-9
Author(s):  
Susanne Meinert ◽  
Elisabeth J. Leehr ◽  
Dominik Grotegerd ◽  
Jonathan Repple ◽  
Katharina Förster ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Diffusion Tensor ◽  
Mean Diffusivity ◽  
Cross Sectional Study ◽  
Disease State ◽  
Major Depressive ◽  
Cross Sectional ◽  
Course Of Illness ◽  
The Right

Abstract Background Eighty percent of all patients suffering from major depressive disorder (MDD) relapse at least once in their lifetime. Thus, understanding the neurobiological underpinnings of the course of MDD is of utmost importance. A detrimental course of illness in MDD was most consistently associated with superior longitudinal fasciculus (SLF) fiber integrity. As similar associations were, however, found between SLF fiber integrity and acute symptomatology, this study attempts to disentangle associations attributed to current depression from long-term course of illness. Methods A total of 531 patients suffering from acute (N = 250) or remitted (N = 281) MDD from the FOR2107-cohort were analyzed in this cross-sectional study using tract-based spatial statistics for diffusion tensor imaging. First, the effects of disease state (acute v. remitted), current symptom severity (BDI-score) and course of illness (number of hospitalizations) on fractional anisotropy (FA), mean diffusivity (MD), radial diffusivity (RD), and axial diffusivity were analyzed separately. Second, disease state and BDI-scores were analyzed in conjunction with the number of hospitalizations to disentangle their effects. Results Disease state (pFWE < 0.042) and number of hospitalizations (pFWE< 0.032) were associated with decreased FA and increased MD and RD in the bilateral SLF. A trend was found for the BDI-score (pFWE > 0.067). When analyzed simultaneously only the effect of course of illness remained significant (pFWE < 0.040) mapping to the right SLF. Conclusions Decreased FA and increased MD and RD values in the SLF are associated with more hospitalizations when controlling for current psychopathology. SLF fiber integrity could reflect cumulative illness burden at a neurobiological level and should be targeted in future longitudinal analyses.

scholarly journals Projective Technique Testing Approach to the Understanding of Psychological Pain in Suicidal and Non-Suicidal Psychiatric Inpatients

2019 ◽  
Vol 17 (1) ◽  
pp. 284
Author(s):  
Isabella Berardelli ◽  
Salvatore Sarubbi ◽  
Alessandra Spagnoli ◽  
Chiara Fina ◽  
Elena Rogante ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Suicide Risk ◽  
Cross Sectional Study ◽  
Psychological Pain ◽  
Major Depressive ◽  
Clinical Factor ◽  
Cross Sectional ◽  
Significant Difference

Psychological pain is a core clinical factor for understanding suicide, independently from depression. The aim of this study is to assess the role of psychological pain on suicide risk and to evaluate the relationship between psychache and different psychiatric disorders. We conducted the present cross-sectional study on 291 inpatients with a diagnosis of major depressive disorder, bipolar disorder, and schizophrenia. We administered Shneidman’s Psychological Pain Assessment Scale (PPAS) for the assessment of mental pain and the Mini International Neuropsychiatric Interview (MINI) for the assessment of suicide risk. There was a significant association between current psychache and worst-ever psychache and suicide risk in inpatients affected by a depressive disorder, bipolar disorder and schizophrenia. Furthermore, we found a significant difference in current psychache between inpatients with major depressive disorder and inpatients with schizophrenia and in worst-ever psychache between inpatients with bipolar disorder and inpatients with schizophrenia, with lower scores in inpatients with schizophrenia. The assessment of psychache appears to be useful for predicting suicidal risk and should be used routinely for identifying and treating suicide risk in clinical practice.

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