scholarly journals Coinfection of Swiss cattle with bovine parainfluenza virus 3 andMycoplasma bovisat acute and chronic stages of bovine respiratory disease complex

2019 ◽  
Vol 31 (5) ◽  
pp. 674-680 ◽  
Author(s):  
Kemal Mehinagic ◽  
Paola Pilo ◽  
Beatriz Vidondo ◽  
Nadine Stokar-Regenscheit
Keyword(s):  
Respiratory Disease ◽  
Defense Mechanisms ◽  
Bovine Respiratory Disease ◽  
Parainfluenza Virus ◽  
Detection Methods ◽  
Single Infection ◽  
Disease Complex ◽  
Bovine Respiratory Disease Complex ◽  
Syncytial Virus ◽  
Bovine Parainfluenza Virus

Viral agents such as bovine respiratory syncytial virus (BRSV) and bovine parainfluenza virus 3 (BPIV-3) are considered primary infectious agents in bovine respiratory disease complex (BRDC). Information regarding the pathogenesis of BRDC is scarce, especially at an advanced chronicity stage, in addition to ongoing coinfection with other primary agents such as Mycoplasma bovis. Based on a retrospective review of histology slides from 104 autopsy cases, we classified cases according to type of pneumonia and chronicity. We performed immunohistochemistry (IHC) for BRSV, BPIV-3, and M. bovis as well as real-time PCR (rtPCR) for M. bovis on lung tissue of all 104 cases and correlated results with the morphologic type of pneumonia. Histomorphologically, 79 cases were classified as bronchopneumonia, 16 as bronchointerstitial pneumonia, and 9 as interstitial pneumonia. In 89 cases, at least 1 of the investigated agents was detected by IHC; 44 of these cases had a coinfection. BPIV-3 was the predominant agent present, as a single infection in 39 cases, and in coinfection with M. bovis in 39 cases. Comparing the detection methods for M. bovis, rtPCR was more specific and sensitive than IHC. The combination of both methods provided a good visual tool for assessing severity and distribution of M. bovis antigen within the tissue. Unlike BRSV, BPIV-3 and M. bovis persisted in chronic BRDC, suggesting ongoing impairment of defense mechanisms in the lung.

scholarly journals Seroprevalence and associated factors of viral agents of the bovine respiratory disease complex in buffaloes of Colombia

2022 ◽  
Vol 52 (8) ◽  
Author(s):  
Misael Enrique Oviedo Pastrana ◽  
Erly Carrascal-Triana ◽  
Matiluz Doria Ramos ◽  
Diego Ortiz Ortega
Keyword(s):  
Respiratory Disease ◽  
Bovine Respiratory Disease ◽  
Diarrhea Virus ◽  
Disease Complex ◽  
High Prevalence ◽  
Bovine Respiratory Disease Complex ◽  
Syncytial Virus ◽  
Viral Diarrhea Virus ◽  
Bovine Parainfluenza Virus ◽  
Transversal Study

ABSTRACT: The bovine respiratory disease complex causes sizable losses for livestock producers. Its presentation involves the interaction among multiple viral and bacterial pathogens. Viral agents include: bovine viral diarrhea virus (BVDV), bovine alphaherpesvírus 1 (BoHV-1), bovine parainfluenza virus (bPI3v) and bovine respiratory syncytial virus (BRSV); so far, these viruses have been little studied in the buffalo population. This study is aimed to assess the presence of these viruses in buffalo populations of the department of Córdoba, Colombia. A transversal study was conducted upon assessment of 37 farms and 861 buffaloes. Seroprevalence in animals were as follows: 21.7% (BVDV), 51.5% (BoHV-1), 73.6% (bPI3v) and 58.9% (BSRV), while seroprevalence in farms stood at: 94.6% (BVDV), 100% (BoHV-1), 100% (bPI3v) and 100% (BSRV). Conversely, the multiple seropositivity in buffaloes or past coinfection of viral agents amounted to 23.3% for a single virus, 31.8% for two viruses, 29.4% for three viruses and 7.1% for four viruses; only 8.4% of buffaloes were seronegative for four viruses. This is the first regional epidemiological study in the buffalo populations of Colombia and the results showed viral circulation and multiple seropositivity in animals; in addition, the high prevalence found pose a concerning epidemiological threat.

scholarly journals Identification and molecular characterisation of bovine parainfluenza virus-3 and bovine respiratory syncytial virus - first report from Turkey

2019 ◽  
Vol 63 (2) ◽  
pp. 167-173 ◽  
Author(s):  
Mehmet Ozkan Timurkan ◽  
Hakan Aydin ◽  
Ahmet Sait
Keyword(s):  
Respiratory Syncytial Virus ◽  
Respiratory Disease ◽  
Bovine Respiratory Disease ◽  
Bovine Respiratory Syncytial Virus ◽  
Parainfluenza Virus ◽  
Molecular Characterisation ◽  
Rt Pcr ◽  
First Report ◽  
Syncytial Virus ◽  
Bovine Parainfluenza Virus

AbstractIntroduction:Bovine parainfluenza virus-3 (BPIV3) and bovine respiratory syncytial virus (BRSV) are the cause of respiratory disease in cattle worldwide. With other pathogens, they cause bovine respiratory disease complex (BRDC) in ruminants. The aim of the study was the detection and molecular characterisation of BPIV3 and BRSV from nasal swabs and lung samples of cows in and around the Erzurum region of eastern Turkey.Material and Methods:In total, 155 samples were collected. Of animals used in the study 92 were males and 63 females. The age of the animals was between 9 months and 5 years, mean 1.4 years. Most males were in the fattening period and being raised in open sheds; females were in the lactating period and kept in free stall barns. All samples were tested for the presence of viral genes using RT-PCR. Gene-specific primers in a molecular method (RT-PCR) identified BRSV (fusion gene) and BPIV3 (matrix gene) strains at the genus level.Results:RNA from BRSV and BPIV3 was detected in two (1.29%) and three (1.93%) samples, respectively, one of each of which was sequenced and the sequences were aligned with reference virus strains. Phylogenetic analyses clustered the strains in genotype C/BPIV3 and subgroup III/BRSV.Conclusion:The results indicate that BRSV and BPIV3 contribute to bovine respiratory disease cases in Turkey. This is the first report on their detection and molecular characterisation in ruminants in Turkey.

scholarly journals Tissue Tropism in Host Transcriptional Response to Members of the Bovine Respiratory Disease Complex

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Susanta K. Behura ◽  
Polyana C. Tizioto ◽  
JaeWoo Kim ◽  
Natalia V. Grupioni ◽  
Christopher M. Seabury ◽  
...  
Keyword(s):  
Respiratory Disease ◽  
Bovine Respiratory Disease ◽  
Transcriptional Response ◽  
Tissue Tropism ◽  
Disease Complex ◽  
Bovine Respiratory Disease Complex

0288 Calculation of genomic predicted transmitting abilities for bovine respiratory disease complex in Holsteins

2016 ◽  
Vol 94 (suppl_5) ◽  
pp. 136-137
Author(s):  
C. P. VanTassell ◽  
G. Spangler ◽  
D. M. Bickhart ◽  
G. R. Wiggans ◽  
J. B. Cole ◽  
...  
Keyword(s):  
Respiratory Disease ◽  
Bovine Respiratory Disease ◽  
Disease Complex ◽  
Bovine Respiratory Disease Complex

scholarly journals Serological Evidence of Influenza D Virus Circulation Among Cattle and Small Ruminants in France

Viruses ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 516 ◽  
Author(s):  
Justine Oliva ◽  
Amit Eichenbaum ◽  
Jade Belin ◽  
Maria Gaudino ◽  
Jean Guillotin ◽  
...  
Keyword(s):  
Respiratory Disease ◽  
Bovine Respiratory Disease ◽  
Small Ruminants ◽  
Serological Evidence ◽  
Disease Complex ◽  
High Prevalence ◽  
Bovine Respiratory Disease Complex ◽  
The Usa

Influenza D virus (IDV) has first been identified in 2011 in the USA and was shown to mainly circulate in cattle. While IDV is associated with mild respiratory signs, its prevalence is still unknown. In the present study we show that IDV has been circulating throughout France in cattle and small ruminants, with 47.2% and 1.5% seropositivity, respectively. The high prevalence and moderate pathogenicity of IDV in cattle suggest that it may play an initiating role in the bovine respiratory disease complex.

Validating loci associated with bovine respiratory disease complex in pre‐weaned Holstein calves

2019 ◽  
Vol 51 (1) ◽  
pp. 91-94
Author(s):  
J.N. Kiser ◽  
M.A. Cornmesser ◽  
R. Blackburn ◽  
S.M. McGuirk ◽  
J.F. Taylor ◽  
...  
Keyword(s):  
Respiratory Disease ◽  
Bovine Respiratory Disease ◽  
Disease Complex ◽  
Bovine Respiratory Disease Complex ◽  
Holstein Calves
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