Metal ion concentrations after metal-on-metal hip arthroplasty are not correlated with habitual physical activity levels

2018 ◽  
Vol 29 (6) ◽  
pp. 638-646 ◽  
Author(s):  
Jetse Jelsma ◽  
Martijn GM Schotanus ◽  
Rachel Senden ◽  
Ide C Heyligers ◽  
Bernd Grimm

Introduction: Metal-on-metal (MoM) hip arthroplasties have shown high clinical failure rates with many patients at risk for a revision and under surveillance for high metal ion concentrations. Implant wear releasing such ions is assumed to be a function of use, i.e. the patient’s physical activity. This study aimed to assess whether habitual physical activity levels of MoM patients are correlated with metal ion concentrations and are higher in patients with high (at risk) than in patients with low (safe) metal ion concentrations. Methods: A cohort study was conducted of patients with any type of MoM hip prosthesis. Metal ion concentrations were determined using ICP-MS. Habitual physical activity of subjects was measured in daily living using an acceleration-based activity monitor. Outcome consisted of quantitative and qualitative activity parameters. Results: In total, 62 patients were included. Mean age at surgery was 60.8 ± 9.3 years and follow-up was 6.3 ± 1.4 years. Cobalt concentrations were highly elevated overall (112.4 ± 137.9 nmol/L) and significantly more in bilateral (184.8 ± 106.5 nmol/L) than in unilateral cases (87.8 ± 139.4 nmol/L). No correlations were found between physical activity parameters and metal ion concentrations. Subgroup analysis of patients with low versus high cobalt concentration showed no significant differences in habitual physical activity. Discussion: No correlation was found between physical activity levels and metal ion concentrations. Implant use by normal habitual activities of daily living seems not to influence metal ion concentrations.

2020 ◽  
Vol 15 (8) ◽  
pp. 1-12
Author(s):  
Chelsea E Moore ◽  
Costas Tsakirides ◽  
Zoe Rutherford ◽  
Michelle G Swainson ◽  
Karen M Birch ◽  
...  

Background/aims The primary aim of this study was to evaluate the effectiveness of two 30-minute dietary education sessions, within cardiac rehabilitation, as a means to optimise nutrient and energy intakes. A secondary aim was to evaluate patients' habitual physical activity levels. Methods Thirty patients (males: n=24, 61.8±11.2 years; females: n=6, 66.7±8.5 years) attended a 6-week early outpatient cardiac rehabilitation programme in the UK and received two 30-minute dietary education sessions emphasising Mediterranean diet principles. Energy intakes and nutrient intakes were measured through completion of 3-day food diaries in weeks one and six (before and after the dietary education sessions) to assess the impact of these sessions on nutrient intakes. At the same time-points, a sub-group (n=13) of patients had their physical activity levels assessed via accelerometery to assess the impact of the cardiac rehabilitation programme on physical activity. Results Estimated energy requirements at week one (1988±366 kcal d−1) were not matched by actual energy intakes (1785±561 kcal d−1) (P=0.047, d=−0.36). Energy intakes reduced to 1655±470 kcal d−1 at week six (P=0.66, d=−0.33) whereas estimated energy requirements increased as a function of increased activity (cardiac rehabilitation sessions). Nutrient intakes remained suboptimal, while no significant increases were observed in healthy fats and fibre, which are core elements of a Mediterranean diet. Statistically significant increases were not observed in physical activity; however, patients decreased sedentary time by 11±12% in week six compared with week one (P=0.009; d=−0.54). Conclusions The present study findings suggest that two 30-minute dietary education sessions did not positively influence energy intakes and nutrient intakes, while habitual physical activity levels were not significantly increased as a result of the cardiac rehabilitation programme. Future research should explore means of optimising nutrition and habitual physical activity within UK cardiac rehabilitation.


2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Shelley E. Keating ◽  
Helen M. Parker ◽  
Toby G. Pavey ◽  
Michael K. Baker ◽  
Ian D. Caterson ◽  
...  

Objective. Epidemiologic studies suggest an inverse relationship between nonalcoholic fatty liver disease (NAFLD), visceral adipose tissue (VAT), and self-reported physical activity levels. However, subjective measurements can be inaccurate and prone to reporter bias. We investigated whether objectively quantified physical activity levels predicted liver fat and VAT in overweight/obese adults.Methods. Habitual physical activity was measured by triaxial accelerometry for four days (n=82). Time spent in sedentary behavior (MET < 1.6) and light (MET 1.6 < 3), moderate (MET 3 < 6), and vigorous (MET 6 < 9) physical activity was quantified. Magnetic resonance imaging and spectroscopy were used to quantify visceral and liver fat. Bivariate correlations and hierarchical multiple regression analyses were performed.Results. There were no associations between physical activity or sedentary behavior and liver lipid. Sedentary behavior and moderate and vigorous physical activity accounted for just 3% of variance for VAT (p=0.14) and 0.003% for liver fat (p=0.96). Higher levels of VAT were associated with time spent in moderate activity (r=0.294,p=0.007), but there was no association with sedentary behavior. Known risk factors for obesity-related NAFLD accounted for 62% and 40% of variance in VAT and liver fat, respectively (p<0.01).Conclusion. Objectively measured levels of habitual physical activity and sedentary behavior did not influence VAT or liver fat.


2016 ◽  
Vol 88 ◽  
pp. 53-58 ◽  
Author(s):  
Mats Hallgren ◽  
Olivia Aya Nakitanda ◽  
Örjan Ekblom ◽  
Matthew P. Herring ◽  
Neville Owen ◽  
...  

2015 ◽  
Vol 7 (1) ◽  
pp. 29-41
Author(s):  
ADEEL NAZIR AHMAD ◽  
KIMBERLEY L. EDWARDS

Background: People with asthma believe their condition prevents them from undertaking physical activity. The objective was to determine the association between habitual physical activity levels and the quality of life in adults with asthma and meeting the physical activity guidelines. Material/Methods: A cross-sectional survey of adults (aged >18) with asthma was conducted in three general practices in Nottingham, UK (n = 128). A self-reported short form International Physical Activity Questionnaire, mini Asthma Quality of Life Questionnaire and a demographic questionnaire (age, gender, ethnicity and BMI) were used to collect data. Physical activity was provided in minutes for different activities to enable the habitual weekly MET-minutes to be calculated, and the quality of life score was determined. Results: Among 128 respondents, 22% met the physical activity guidelines. Mostly younger, white, male, normal weight participants had higher physical activity levels and better asthma quality of life. Mean total asthma quality of life score was 4.5. Linear regression modelling showed a positive association between the total physical activity and the quality of life score (p < 0.001); thus higher physical activity levels were associated with less/no asthma quality of life impairment (higher score). Conclusions: The majority of asthmatics in this study had low physical activity levels, did not meet the recommended physical activity guidelines and had impaired quality of life. A strong positive association between physical activity and asthma quality of life supports the view that adults with asthma should be encouraged to be sufficiently physically active, which could be associated with a better asthma related quality of life.


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