scholarly journals The culture of hope and ethical challenges in clinical trials: A qualitative study of oncologists and haematologists’ views

2019 ◽  
Vol 15 (1) ◽  
pp. 29-38 ◽  
Author(s):  
Tove E Godskesen ◽  
Suzanne Petri ◽  
Stefan Eriksson ◽  
Arja Halkoaho ◽  
Margrete Mangset ◽  
...  
Keyword(s):  
Health Care ◽  
Clinical Trials ◽  
Qualitative Study ◽  
Empirical Research ◽  
Health Care Professionals ◽  
Therapeutic Misconception ◽  
Ethical Challenges ◽  
Know How ◽  
Ethical Concerns ◽  
Clinical Cancer

We do not know how much clinical physicians carrying out clinical trials in oncology and haematology struggle with ethical concerns. To our knowledge, no empirical research exists on these questions in a Nordic context. Therefore, this study aims to learn what kinds of ethical challenges physicians in Sweden, Denmark and Finland (n = 29) face when caring for patients in clinical trials; and what strategies, if any, they have developed to deal with them. The main findings were that clinical cancer trials pose ethical challenges related to autonomy issues, unreasonable hope for benefits and the therapeutic misconception. Nevertheless, some physicians expressed that struggling with such challenges was not of great concern. This conveys a culture of hope where health care professionals and patients uphold hope and mutually support belief in clinical trials. This culture being implicit, physicians need opportunities to deliberately reflect over the characteristics that should constitute this culture.

scholarly journals A Roadmap to Inform Development, Validation and Approval of Digital Mobility Outcomes: The Mobilise-D Approach

2020 ◽  
Vol 4 (1) ◽  
pp. 13-27 ◽  
Author(s):  
Lynn Rochester ◽  
Claudia Mazzà ◽  
Arne Mueller ◽  
Brian Caulfield ◽  
Marie McCarthy ◽  
...  
Keyword(s):  
Health Care ◽  
Clinical Trials ◽  
Health Care Professionals ◽  
Digital Health ◽  
Disease Status ◽  
Proximal Femoral Fracture ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Physical Mobility ◽  
High Level

Health care has had to adapt rapidly to COVID-19, and this in turn has highlighted a pressing need for tools to facilitate remote visits and monitoring. Digital health technology, including body-worn devices, offers a solution using digital outcomes to measure and monitor disease status and provide outcomes meaningful to both patients and health care professionals. Remote monitoring of physical mobility is a prime example, because mobility is among the most advanced modalities that can be assessed digitally and remotely. Loss of mobility is also an important feature of many health conditions, providing a read-out of health as well as a target for intervention. Real-world, continuous digital measures of mobility (digital mobility outcomes or DMOs) provide an opportunity for novel insights into health care conditions complementing existing mobility measures. Accepted and approved DMOs are not yet widely available. The need for large collaborative efforts to tackle the critical steps to adoption is widely recognised. Mobilise-D is an example. It is a multidisciplinary consortium of 34 institutions from academia and industry funded through the European Innovative Medicines Initiative 2 Joint Undertaking. Members of Mobilise-D are collaborating to address the critical steps for DMOs to be adopted in clinical trials and ultimately health care. To achieve this, the consortium has developed a roadmap to inform the development, validation and approval of DMOs in Parkinson’s disease, multiple sclerosis, chronic obstructive pulmonary disease and recovery from proximal femoral fracture. Here we aim to describe the proposed approach and provide a high-level view of the ongoing and planned work of the Mobilise-D consortium. Ultimately, Mobilise-D aims to stimulate widespread adoption of DMOs through the provision of device agnostic software, standards and robust validation in order to bring digital outcomes from concept to use in clinical trials and health care.

Health-care professionals’ perceived trust in and willingness to recommend functional foods: A qualitative study

Appetite ◽  
2007 ◽  
Vol 48 (2) ◽  
pp. 241-247 ◽  
Author(s):  
Eva Landström ◽  
Birgitta Sidenvall ◽  
Ulla-Kaisa Koivisto Hursti ◽  
Maria Magnusson
Keyword(s):  
Health Care ◽  
Qualitative Study ◽  
Health Care Professionals ◽  
Functional Foods ◽  
Perceived Trust ◽  
Willingness To Recommend

Distinguishing between Assisting and Substituting for Vital Organs

2016 ◽  
Vol 41 (9) ◽  
pp. 1-2
Author(s):  
Alfred Cioffi ◽  
Keyword(s):  
Health Care ◽  
End Of Life ◽  
Health Care Professionals ◽  
Moral Obligation ◽  
Life Support ◽  
Vital Organ ◽  
Vital Function ◽  
Know How ◽  
Futile Care ◽  
Extraordinary Means

When patients approach the end of life, their loved ones often do not know how much treatment is too much and struggle to decide when to stop intervening and allow them to die in peace. Conversely, health care professionals may tend to prescribe extraordinary means of life support, sometimes simply because of legal and fiscal concerns or a family’s request for futile care. It can be useful to refer to the general bioethical principle that, typically, there is no moral obligation to provide a substitute for vital organs. In this context, providing a substitute for a vital organ means wholly replacing the vital function of the dying organ by means of either a transplant or medical machinery. This article seeks to explain how this rule may be applied when a patient and his family are deciding at what point to stop treatment and allow the patient to die in peace.

scholarly journals A Study of awareness, attitude and practice of pharmacovigilance among health care professionals in a tertiary care teaching hospital in Bareilly, India

2017 ◽  
Vol 6 (7) ◽  
pp. 1784
Author(s):  
Krishna Singh ◽  
Kauser Sayedda ◽  
Richa Bhardwaj ◽  
Neha Yadav ◽  
Quazi Shahir Ahmed
Keyword(s):  
Health Care ◽  
Health Care Professionals ◽  
Response Rate ◽  
Tertiary Care ◽  
Faculty Members ◽  
Medical Sciences ◽  
Cross Sectional ◽  
Know How ◽  
Attitude And Practice ◽  
Knowledge And Attitude

Background: Awareness towards Pharmacovigilance among health professionals in any hospital is an important part of health care system. So, the present study was conducted to know the extent of awareness of Pharmacovigilance among health care professionals.Methods: A cross-sectional questionnaire based study about knowledge, attitude and practices towards adverse drugs reaction (ADRs) and Pharmacovigilance was carried out at Shri Ram Murti Smarak Institue of Medical Sciences, Bareilly (U.P). 153 questionnaires were distributed among the Post graduate students, faculties, interns, nurses and pharmacists. 2-3 days time was given to fill the questionnaire.Results: Out of 153 questionnaires distributed, 99 filled forms were turned up for evaluation. Hence, response rate was 64.70%. 73.33% PGs, 100% faculty members, 53.33% interns, 36% nurses and 18.75% pharmacists were aware of adverse drugs reactions (ADRs) and Pharmacovigilance. Regarding reporting of ADRs, 86.66% PGs, 91.66% faculties, 73.33% interns, 88% nurses and 81.25% pharmacists were agreed to report ADR as it is mandatory and related to increased patients’ safety. Regarding discouraging factors for practice of reporting ADRs, 20% PGs, 16.66% faculties, 80% interns, 40% nurses and 68.75% pharmacists found ADR forms difficult to be filled. According to 66% faculties, 80% PGs, 66.66% interns managing patients are more important than reporting ADRs while 93.75% nurses and 76% pharmacists did not know how to report and where to report.Conclusions: The results of our study indicate that the acceptable number of health-care professionals had a good knowledge and attitude towards pharmacovigilance. There was a huge gap between the ADR experienced, and ADR reported by the health-care professionals. So, there is need of conductance of CMEs, workshops and seminars related to pharmacovigilance for all heaith care professionals especially nurses and pharmacists so, that whole community can be benefitted.

scholarly journals Social and Health System Complexities Impacting on Decision-Making for Utilization of Oncology and Palliative Care in an African Context: A Qualitative Study

2019 ◽  
Vol 35 (3) ◽  
pp. 185-191 ◽  
Author(s):  
David A. Agom ◽  
Stuart Allen ◽  
Sarah Neill ◽  
Judith Sixsmith ◽  
Helen Poole ◽  
...  
Keyword(s):  
Health Care ◽  
Decision Making ◽  
Palliative Care ◽  
Qualitative Study ◽  
Health Care System ◽  
Health Care Professionals ◽  
Care Delivery ◽  
Semistructured Interview ◽  
Design Data ◽  
Care System

Background: There is a dearth of research focusing on identifying the social complexities impacting on oncology and palliative care (PC), and no study has explored how the health-care system in Nigeria or other African contexts may be influencing utilization of these services. Aim: This study explored how social complexities and the organization of health-care influenced the decision-making process for the utilization of oncology and PC in a Nigerian hospital. Methods: This qualitative study used an interpretive descriptive design. Data were collected using semistructured interview guides with 40 participants, comprising health-care professionals, patients, and their families. Thematic analysis was conducted to generate and analyze patterns within the data. Findings: Three themes were identified: dysfunctional structural organization of the health-care delivery system, service-users’ economic status, and the influence of social networks. The interrelationship between the themes result in patients and their family members decisions either to present late to the hospital, miss their clinical appointments, or not to seek oncological health care and PC. Conclusion: This article offers insights into the role of the health-care system, as organized currently in Nigeria, as “autoinhibitory” and not adequately prepared to address the increasing burden of cancer. We therefore argue that there is a need to restructure the Nigerian health-care system to better meet the needs of patients with cancer and their families as failure to do so will strengthen the existing inequalities, discourage usage, and increase mortality.

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