Salivary Proteins Interact with Dietary Constituents to Modulate Tooth Staining

2005 ◽  
Vol 84 (1) ◽  
pp. 73-78 ◽  
Author(s):  
G.B. Proctor ◽  
R. Pramanik ◽  
G.H. Carpenter ◽  
G.D. Rees
Keyword(s):  
Red Wine ◽  
Black Tea ◽  
Salivary Protein ◽  
Salivary Proteins ◽  
Parotid Saliva ◽  
Grape Skin ◽  
Dietary Components ◽  
Black Tea Polyphenols ◽  
Proline Rich Protein

Dietary components rich in polyphenols—for example, tea and red wine—are thought to cause tooth staining. In the present study, hydroxyapatite was used as a model of enamel for study of the influence of salivary proteins on the binding of different polyphenols to hydroxyapatite in vitro. Neither salivary protein pellicles nor salivary proteins in solution significantly altered the binding of the small polyphenol epigallocatechin to hydroxyapatite. However, hydroxyapatite binding of anthocyanin, a small grape-skin-derived polyphenol, or the larger polyphenols of black tea was increased by the presence of salivary proteins, either as a pellicle or in solution. Proline-rich proteins were enriched from parotid saliva and found to increase binding of anthocyanin and black tea polyphenols to hydroxyapatite, while enriched histatins did not increase binding. It is concluded that some salivary proteins, including proline-rich protein, can mediate increased staining of enamel by red-wine- and black-tea-derived polyphenols.

scholarly journals Anti-trichomonad activities of different compounds from foods, marine products, and medicinal plants: a review

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Mendel Friedman ◽  
Christina C. Tam ◽  
Luisa W. Cheng ◽  
Kirkwood M. Land
Keyword(s):  
Trichomonas Vaginalis ◽  
Transmitted Disease ◽  
Black Tea ◽  
Farm Animals ◽  
Grape Skin ◽  
Plant Essential Oils ◽  
Beneficial Effects ◽  
Medicinal Plant Extracts ◽  
Pure Compounds

Abstract Human trichomoniasis, caused by the pathogenic parasitic protozoan Trichomonas vaginalis, is the most common non-viral sexually transmitted disease that contributes to reproductive morbidity in affected women and possibly to prostate cancer in men. Tritrichomonas foetus strains cause the disease trichomoniasis in farm animals (cattle, bulls, pigs) and diarrhea in domestic animals (cats and dogs). Because some T. vaginalis strains have become resistant to the widely used drug metronidazole, there is a need to develop alternative treatments, based on safe natural products that have the potential to replace and/or enhance the activity of lower doses of metronidazole. To help meet this need, this overview collates and interprets worldwide reported studies on the efficacy of structurally different classes of food, marine, and medicinal plant extracts and some of their bioactive pure compounds against T. vaginalis and T. foetus in vitro and in infected mice and women. Active food extracts include potato peels and their glycoalkaloids α-chaconine and α-solanine, caffeic and chlorogenic acids, and quercetin; the tomato glycoalkaloid α-tomatine; theaflavin-rich black tea extracts and bioactive theaflavins; plant essential oils and their compounds (+)-α-bisabolol and eugenol; the grape skin compound resveratrol; the kidney bean lectin, marine extracts from algae, seaweeds, and fungi and compounds that are derived from fungi; medicinal extracts and about 30 isolated pure compounds. Also covered are the inactivation of drug-resistant T. vaginalis and T. foetus strains by sensitized light; anti-trichomonad effects in mice and women; beneficial effects of probiotics in women; and mechanisms that govern cell death. The summarized findings will hopefully stimulate additional research, including molecular-mechanism-guided inactivations and human clinical studies, that will help ameliorate adverse effects of pathogenic protozoa.

scholarly journals In Vitro Bioconversion of Polyphenols from Black Tea and Red Wine/Grape Juice by Human Intestinal Microbiota Displays Strong Interindividual Variability

2010 ◽  
Vol 58 (18) ◽  
pp. 10236-10246 ◽  
Author(s):  
Gabriele Gross ◽  
Doris M. Jacobs ◽  
Sonja Peters ◽  
Sam Possemiers ◽  
John van Duynhoven ◽  
...  
Keyword(s):  
Intestinal Microbiota ◽  
Red Wine ◽  
Interindividual Variability ◽  
Grape Juice ◽  
Black Tea ◽  
Wine Grape ◽  
Human Intestinal Microbiota

scholarly journals In Vitro Salivary Protein Adsorption Profile on Titanium and Ceramic Surfaces and the Corresponding Putative Immunological Implications

2020 ◽  
Vol 21 (9) ◽  
pp. 3083 ◽  
Author(s):  
Chen-Xuan Wei ◽  
Michael Francis Burrow ◽  
Michael George Botelho ◽  
Henry Lam ◽  
Wai Keung Leung
Keyword(s):  
Immune Responses ◽  
Interaction Network ◽  
Salivary Protein ◽  
Microbial Interactions ◽  
Salivary Proteins ◽  
Material Surface ◽  
Go Annotation ◽  
Implant Abutment ◽  
Adsorbed Proteins

Immune responses triggered by implant abutment surfaces contributed by surface-adsorbed proteins are critical in clinical implant integration. How material surface-adsorbed proteins relate to host immune responses remain unclear. This study aimed to profile and address the immunological roles of surface-adsorbed salivary proteins on conventional implant abutment materials. Standardized polished bocks (5 × 5 × 1 mm3) were prepared from titanium and feldspathic ceramic. Salivary acquired pellicle formed in vitro was examined by liquid chromatography-tandem mass spectrometry and gene ontology (GO) analysis to identify and characterize the adsorbed proteins. Out of 759 proteins identified from pooled saliva samples, 396 were found to be attached to the two materials tested—369 on titanium and 298 on ceramic, with 281 common to both. GO annotation of immune processes was undertaken to form a protein–protein interaction network, and 14 hub proteins (≥6 interaction partners) (coding genes: B2M, C3, CLU, DEFA1, HSP90AA1, HSP90AB1, LTF, PIGR, PSMA2, RAC1, RAP1A, S100A8, S100A9, and SLP1) were identified as the key proteins connecting multiple (6–9) immune processes. The results offered putative immunological prospects of implant abutment material surface-adsorbed salivary proteins, which could potentially underpin the dynamic nature of implant–mucosal/implant–microbial interactions.

scholarly journals Influence of supplementation with two specific inactivated dry yeast and grape-skin extract on the color and composition of red wine

2019 ◽  
Vol 12 ◽  
pp. 02004
Author(s):  
J. Gombau ◽  
P. Pons ◽  
D. Fernández ◽  
J.M. Heras ◽  
N. Sieczkowski ◽  
...  
Keyword(s):  
Red Wine ◽  
Salivary Proteins ◽  
Cabernet Sauvignon ◽  
Skin Extract ◽  
Grape Skin ◽  
Released Polysaccharides ◽  
Grape Skin Extract

Wines from grapes of Cabernet Sauvignon of the AOC Tarragona were elaborated with supplementation or not of two specific inactivated dry yeasts (Optired® and Optimum Red®; Lallemand Inc.) or with an experimental grape-skin extract. All the wines treated were significantly less astringent than the control wine because both inactivated dry yeast and the skin extract released polysaccharides which probably inhibit interactions between salivary proteins and tannins, and because their presence decrease the proportion of seed tannins and increase the proportion of skin tannins in the final wines.

Prevention of diet-induced obesity by dietary black tea polyphenols extract in vitro and in vivo

Nutrition ◽  
2011 ◽  
Vol 27 (3) ◽  
pp. 287-292 ◽  
Author(s):  
Satoshi Uchiyama ◽  
Yoshimasa Taniguchi ◽  
Akiko Saka ◽  
Aruto Yoshida ◽  
Hiroaki Yajima
Keyword(s):  
Black Tea ◽  
Tea Polyphenols ◽  
Diet Induced Obesity ◽  
Black Tea Polyphenols
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