scholarly journals Measuring Differential Volume Using the Subtraction Tool for Three-Dimensional Breast Volumetry: A Proof of Concept Study

2020 ◽  
pp. 155335062094556
Author(s):  
Faith Hyun Kyung Jeon ◽  
Michelle Griffin ◽  
Aurora Almadori ◽  
Jajini Varghese ◽  
Stephanie Bogan ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Computer Software ◽  
Patient Positioning ◽  
Volumetric Analysis ◽  
Volumetric Assessment ◽  
Alternative Approach ◽  
Significant Difference ◽  
Actual Volume ◽  
Novel Method ◽  
The Subject

Background. Three-dimensional (3D) photography provides a promising means of breast volumetry. Sources of error using a single-captured surface to calculate breast volume include inaccurate designation of breast boundaries and prediction of the invisible chest wall generated by computer software. An alternative approach is to measure differential volume using subtraction of 2 captured surfaces. Objectives. To explore 3D breast volumetry using the subtraction of superimposed images to calculate differential volume. To assess optimal patient positioning for accurate volumetric assessment. Methods. Known volumes of breast enhancers simulated volumetric changes to the breast (n = 12). 3D photographs were taken (3dMDtorso) with the subject positioned upright at 90° and posteriorly inclined at 30°. Patient position, breathing, distance and camera calibration were standardised. Volumetric analysis was performed using 3dMDvultus software. Results. A statistically significant difference was found between actual volume and measured volumes with subjects positioned at 90° ( P < .05). No statistical difference was found at 30° ( P = .078), but subsequent Bland–Altman analysis showed evidence of proportional bias ( P < .05). There was good correlation between measured and actual volumes in both positions (r = .77 and r = .85, respectively). Univariate analyses showed breast enhancer volumes of 195 mL and 295 mL to incur bias. The coefficient of variation was 5.76% for single observer analysis. Conclusion. Positioning the subject at a 30° posterior incline provides more accurate results from better exposure of the inferior breast. The subtraction tool is a novel method of measuring differential volume. Future studies should explore methodology for application into the clinical setting.

scholarly journals Role of multislice computed tomography 3D volumetric analysis in the assessment of the therapeutic response of hepatocellular carcinoma after transarterial chemoembolization

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Mohamed Fouad Osman ◽  
Ahmed Shawky Ali Farag ◽  
Haney Ahmed Samy ◽  
Tamer Mahmoud El-Baz ◽  
Shaima Fattouh Elkholy
Keyword(s):  
Hepatocellular Carcinoma ◽  
Transarterial Chemoembolization ◽  
Therapeutic Response ◽  
Interventional Procedure ◽  
Liver Volume ◽  
Three Dimensional ◽  
Volumetric Analysis ◽  
Three Dimensions ◽  
Locoregional Therapy ◽  
Significant Difference

Abstract Background Volumetric analysis is a novel radiological technique used in the measurement of target lesions in three dimensions in order to estimate the lesion’s volume. Recently, it has been used for evaluation of the remaining liver volume after partial hepatectomy and also for evaluation of the response of tumours to treatment. It has been proven to be more accurate than the standard one or two-dimensional measurements, and it is especially useful for the evaluation of complex tumours after radiological interventional methods when the use of standard methods is limited. In the current study, our aim was to evaluate the value of the three-dimensional (3D) volumetric method “Response Evaluation Criteria in Solid Tumours (vRECIST)” and to compare it with the non–three-dimensional methods (RECIST) and modified RECIST (mRECIST) in the assessment of the therapeutic response of hepatocellular carcinoma (HCC) after transarterial chemoembolization (TACE). Results A retrospective study was conducted on 50 patients with confirmed radiological or pathological diagnosis of hepatocellular carcinoma (HCC) who underwent TACE as the only interventional procedure and follwed up by triphasic CT 1 and 4 months after treatment. The study revealed a significant difference between mRECIST and vRECIST in the assessment of the therapeutic response of HCC after TACE, a weak agreement was found between both methods in the detection of complete response (CR), partial response (PR), stable disease (SD) or progressive disease (PD). Also, there was no significant agreement between mRECIST and vRECIST regarding the assessment by classifying the patients into responders or nonresponders. Conclusion Volumetric analysis is an effective method for measuring the HCC lesions and evaluating its response to locoregional treatment with a significant difference between vRECIST and mRECIST in the assessment of therapeutic response, which in turn help the interventional radiologist to decide the future treatments and change the therapeutic plans. Based on these results, we recommend vRECIST to be an essential part of the assessment of therapeutic response after locoregional therapy.

Stage IA to IIB mediastinal Hodgkin's disease: three-dimensional volumetric assessment of response to treatment.

1988 ◽  
Vol 6 (5) ◽  
pp. 819-824 ◽  
Author(s):  
C G Willett ◽  
R M Linggood ◽  
J C Leong ◽  
L M Miketic ◽  
M A Stracher ◽  
...  
Keyword(s):  
Hodgkin's Disease ◽  
Hodgkin’S Disease ◽  
Three Dimensional ◽  
Volumetric Analysis ◽  
Response To Treatment ◽  
Initial Volume ◽  
Volumetric Assessment ◽  
Mediastinal Disease ◽  
Stage Ia ◽  
The Mean

From 1979 to 1986, the response to treatment of 53 patients with stage IA to IIB mediastinal Hodgkin's disease was evaluated by three-dimensional volumetric analysis using thoracic computed tomographic (CT) scans. The mean initial volume of mediastinal disease in 34 patients treated with mantle and para-aortic irradiation was 166 mL, whereas for 19 patients treated with two to six cycles of multiagent chemotherapy and mantle and para-aortic irradiation the mean initial volume was 446 mL. Preliminary data suggested that patients with mediastinal volumes of less than 200 mL had a lower mediastinal relapse rate (13%) than patients with volumes greater than 200 mL (32%). For 12 patients receiving six cycles of nitrogen mustard, vincristine, procarbazine, and prednisone (MOPP), those with a greater than 85% reduction in volume 1 to 2 months after chemotherapy had a lower incidence of mediastinal relapse (zero of six, 0%) compared with patients having 85% or less reduction in volume (four of six, 67%). The primary value of this technique is that it provides a sensitive assessment of response to treatment and may aid in monitoring the effectiveness of a given treatment.

scholarly journals Templating in shoulder arthroplasty – A comparison of 2D CT to 3D CT planning software: A systematic review

2019 ◽  
Vol 12 (5) ◽  
pp. 303-314
Author(s):  
Oluwatobi R Olaiya ◽  
Ibrahim Nadeem ◽  
Nolan S Horner ◽  
Asheesh Bedi ◽  
Timothy Leroux ◽  
...  
Keyword(s):  
Systematic Review ◽  
Shoulder Arthroplasty ◽  
Preoperative Planning ◽  
Total Shoulder Arthroplasty ◽  
Three Dimensional ◽  
Computer Software ◽  
3D Ct ◽  
Radiographic Outcomes ◽  
Significant Difference ◽  
2D And 3D

Background Computed tomography (CT) utilizing computer software technology to generate three-dimensional (3D) rendering of the glenoid has become the preferred method for preoperative planning. It remains largely unknown what benefits this software may have to the intraoperative placement of the components and patient outcomes. Purpose The purpose of this systematic review is to compare 2D CT to 3D CT planning in total shoulder arthroplasty. Study design Systematic review. Methods A systematic database search was conducted for relevant studies evaluating the role of 3D CT planning in total shoulder arthroplasty. The primary outcome was component placement variability, and the secondary outcomes were intra- and inter-observer reliability in the context of preoperative planning. Results Following title-abstract and full-text screening, six eligible studies were included in the review (n = 237). The variability in glenoid measurements between 3D CT and 2D CT planning ranged from no significant difference to a 5° difference in version and 1.7° difference in inclination (p<0.05). Posterior bone loss was underestimated in 52% of the 2D measured patients relative to 3D CT groups. Irrespective of 2D and 3D planning (39% and 43% of cases respectively), surgeons elected to implant larger components than those templated. There was no literature identified comparing differences in time, cost, functional outcomes, complications, or patient satisfaction. Conclusion The paucity of evidence exploring clinical parameters makes it difficult to comment on clinical outcomes using different methods of templating. More studies are required to identify how improved radiographic outcomes translate into improvements that are clinically meaningful to patients.

scholarly journals A novel method for volumetric assessment of tooth wear using three-dimensional reverse-engineering technology: A preliminary report

2014 ◽  
Vol 84 (4) ◽  
pp. 687-692 ◽  
Author(s):  
Jina Park ◽  
Dong-Soon Choi ◽  
Insan Jang ◽  
Hyun-Tae Yook ◽  
Paul-Georg Jost-Brinkmann ◽  
...  
Keyword(s):  
Reverse Engineering ◽  
Preliminary Report ◽  
Three Dimensional ◽  
Tooth Wear ◽  
Engineering Technology ◽  
Volumetric Assessment ◽  
Novel Method

scholarly journals Multiple Representation-Based Learning through Cognitive Dissonance Strategy to Reduce Student’s Misconceptions in Volumetric Analysis

TEM Journal ◽  
2021 ◽  
pp. 1263-1273
Author(s):  
Hayuni Retno Widarti ◽  
Anna Permanasari ◽  
Sri Mulyani ◽  
Deni Ainur Rokhim ◽  
Habiddin Habiddin
Keyword(s):  
Cognitive Dissonance ◽  
Mixed Method ◽  
Volumetric Analysis ◽  
Mixed Method Research ◽  
Multiple Representation ◽  
Chemistry Students ◽  
Symbolic Representations ◽  
Significant Difference ◽  
Effective Reduction ◽  
The Subject

This study aimed to determine the contribution of multiple representation-based learning through cognitive dissonance strategy and to reduce misconceptions encountered by chemistry students. A mixed method research with the embedded experimental design was employed in this study involving 66 sophomore students enrolled in the Basics of Analytical Chemistry class. This study used a threetier test diagnostic test of 43 questions that had been validated by the education teams and chemists. The analysis was done by using a t-test and N-gain. The results showed a significant difference between the experimental and the control classes and a greater increase in N-gain in the experimental class (68.56%) compared to the control class (42.42%). The most effective reduction of misconceptions occurred in the subject of argentometric titration, from 33.41 to 8.79 %. This indicates that MRCD cannot completely eliminate misconceptions, especially for concepts related to sub-microscopic and symbolic representations.

scholarly journals Three-dimensional semi-automated volumetric assessment of the pulp space of teeth following regenerative dental procedures

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Heeresh Shetty ◽  
Shishir Shetty ◽  
Adesh Kakade ◽  
Aditya Shetty ◽  
Mohmed Isaqali Karobari ◽  
...  
Keyword(s):  
Medical Imaging ◽  
Open Source ◽  
Three Dimensional ◽  
Volume Estimation ◽  
Permanent Teeth ◽  
3D Slicer ◽  
Link Type ◽  
Volumetric Assessment ◽  
Critical Measure ◽  
Significant Difference

AbstractThe volumetric change that occurs in the pulp space over time represents a critical measure when it comes to determining the secondary outcomes of regenerative endodontic procedures (REPs). However, to date, only a few studies have investigated the accuracy of the available domain-specialized medical imaging tools with regard to three-dimensional (3D) volumetric assessment. This study sought to compare the accuracy of two different artificial intelligence-based medical imaging programs namely OsiriX MD (v 9.0, Pixmeo SARL, Bernex Switzerland, https://www.osirix-viewer.com) and 3D Slicer (http://www.slicer.org), in terms of estimating the volume of the pulp space following a REP. An Invitro assessment was performed to check the reliability and sensitivity of the two medical imaging programs in use. For the subsequent clinical application, pre- and post-procedure cone beam computed tomography scans of 35 immature permanent teeth with necrotic pulp and periradicular pathosis that had been treated with a cell-homing concept-based REP were processed using the two biomedical DICOM software programs (OsiriX MD and 3D Slicer). The volumetric changes in the teeth’s pulp spaces were assessed using semi-automated techniques in both programs. The data were statistically analyzed using t-tests and paired t-tests (P = 0.05). The pulp space volumes measured using both programs revealed a statistically significant decrease in the pulp space volume following the REP (P < 0.05), with no significant difference being found between the two programs (P > 0.05). The mean decreases in the pulp space volumes measured using OsiriX MD and 3D Slicer were 25.06% ± 19.45% and 26.10% ± 18.90%, respectively. The open-source software (3D Slicer) was found to be as accurate as the commercially available software with regard to the volumetric assessment of the post-REP pulp space. This study was the first to demonstrate the step-by-step application of 3D Slicer, a user-friendly and easily accessible open-source multiplatform software program for the segmentation and volume estimation of the pulp spaces of teeth treated with REPs.

scholarly journals Applying constrained virtual environments to serious games for heritage

2019 ◽  
Vol 6 (1) ◽  
pp. 93-116 ◽  
Author(s):  
Laurence Hanes ◽  
Robert Stone
Keyword(s):  
Virtual Environments ◽  
Serious Games ◽  
Three Dimensional ◽  
Museum Displays ◽  
3D Environment ◽  
Alternative Approach ◽  
Subsequent Interview ◽  
3D Environments ◽  
Exploratory Experiment ◽  
The Subject

Virtual environments are an important aspect of serious games for heritage. However navigable three-dimensional (3D) environments can be costly and resource-intensive to create and for users to run. In this paper, we propose an alternative approach using “constrained virtual environments”, which present an environment through a series of reduced fidelity two-dimensional (2D) scenes without exhaustive detail. We describe the development of a constrained virtual environment to replicate a 3D environment from a serious game concerning ancient Mesopotamian history. An exploratory experiment discovered that participants experienced a similar sense of presence in the constrained environment to that of the 3D environment and rated the two games to be of similar quality. Participants were equally likely to pursue further information on the subject matter afterwards and collected more information tokens from within the constrained environment. A subsequent interview with a museum expert explored opportunities for such games to be implemented in museum displays, and based on the experiences and issues encountered, a preliminary set of guidelines was compiled for implementing future constrained virtual environments within serious games for heritage.

scholarly journals Direct and virtual measurements of abdominal aortic aneurysms: three-dimensional printed models

2021 ◽  
Vol 54 (1) ◽  
pp. 21-26
Author(s):  
Giovanna Ricarte Granja Gomes ◽  
Marcos Cordeiro D’Ornellas ◽  
Gustavo Nogara Dotto
Keyword(s):  
Computed Tomography ◽  
Three Dimensional ◽  
Preoperative Assessment ◽  
Volumetric Analysis ◽  
Aortic Aneurysms ◽  
Three Dimensional Printing ◽  
Volumetric Assessment ◽  
Abdominal Aortic ◽  
Printing System ◽  
The Difference

Abstract Objective: To validate the use of a three-dimensional printing system for metric and volumetric analysis of the segments of an abdominal aortic aneurysm (AAA). Materials and Methods: In patients scheduled to undergo endovascular AAA repair, the computed tomography angiography (CTA) measurements obtained during the preoperative assessment of the patients were compared with those obtained by computed tomography of individualized three-dimensional biomodels. Results: The volumetric assessment showed a discrepancy of 3-12%, and the difference between the areas was 10-16%. Conclusion: Computed tomography measurements of 3D-printed biomodels of AAAs appear to be comparable to those of threedimensional CTA measurements of the same AAAs, in terms of the metric and volumetric dimensions.

scholarly journals Three-dimensional Semi-Automated Volumetric Assessment of the Pulp Space of Teeth with Regenerative Dental Procedures

2021 ◽  
Author(s):  
Heeresh Shetty ◽  
Shishir Shetty ◽  
Adesh Kakade ◽  
Aditya Shetty ◽  
Mohmed Isaqali Karobari ◽  
...  
Keyword(s):  
Open Source ◽  
Three Dimensional ◽  
T Test ◽  
Volume Estimation ◽  
Permanent Teeth ◽  
3D Slicer ◽  
Volumetric Assessment ◽  
Critical Measure ◽  
Significant Difference ◽  
Space Volume

Abstract Volumetric change of the pulp space over time is a critical measure to determine the outcome of regenerative endodontic procedures (REP). There is a paucity in the literature on the accuracy of domain specialized medical imaging tools for three dimensional (3D) volumetric assessment. Thus, the aim of this study was to compare two different medical image computing platforms (OsiriX MD and 3D Slicer) to estimate the volume of pulp space post REP. Pre and post CBCT Scans of 35 immature permanent teeth (n = 35) with necrotic pulp and periradicular pathosis treated with a cell-homing concept-based REP were processed using two biomedical DICOM software programs: OsiriX MD (commercially available, FDA approved) 2) and 3D Slicer (open source). Volumetric changes in the pulp space were assessed using semi-automated techniques in both the programmes. The data were statistically analyzed using t-test and paired t-test (P = 0.05). The pulp space volume measured with both the programmes showed a statistically significant decrease in pulp space volume post REP (P < 0.05), with no significant difference between the two programmes (P > 0.05). The mean decrease in pulp space volume with OsiriX MD and 3D Slicer were 25.06% ± 19.45% and 26.10.% ± 18.90% respectively. The open-source software (3D Slicer) was as accurate as the commercially available software for the volumetric assessment of the pulp space post REP. This study demonstrates the step-by-step application of 3D Slicer, a user-friendly, easily accessible, open-source multiplatform software for the segmentation and volume estimation of the pulp-space of teeth treated with REP.

The removal and morphology of intact biofilms from implanted venous access devices

1995 ◽  
Vol 53 ◽  
pp. 1020-1021
Author(s):  
M.A. Gregory ◽  
G.P. Hadley
Keyword(s):  
Patient Selection ◽  
Surgical Oncology ◽  
Venous Access ◽  
Common Procedure ◽  
Indwelling Catheters ◽  
Careful Patient ◽  
Novel Method ◽  
The Subject ◽  
Vascular Catheters ◽  
Venous Access Devices

The insertion of implanted venous access systems for children undergoing prolonged courses of chemotherapy has become a common procedure in pediatric surgical oncology. While not permanently implanted, the devices are expected to remain functional until cure of the primary disease is assured. Despite careful patient selection and standardised insertion and access techniques, some devices fail. The most commonly encountered problems are colonisation of the device with bacteria and catheter occlusion. Both of these difficulties relate to the development of a biofilm within the port and catheter. The morphology and evolution of biofilms in indwelling vascular catheters is the subject of ongoing investigation. To date, however, such investigations have been confined to the examination of fragments of biofilm scraped or sonicated from sections of catheter. This report describes a novel method for the extraction of intact biofilms from indwelling catheters.15 children with Wilm’s tumour and who had received venous implants were studied. Catheters were removed because of infection (n=6) or electively at the end of chemotherapy.

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