Copper Alginate-Cotton Cellulose (CACC) Fibers with Excellent Antibacterial Properties

The present work describes synthesis of copper alginate-cotton cellulose (CACC) composite fibers and detailed investigation of antimicrobial action against the model bacteria E.coli. The CACC fibers were prepared by immersing cotton fibers in aqueous solution of sodium alginate, followed by ionic crosslinking of alginate chains within the cotton cellulose fibers with Cu(II) ions to yield CACC composite fibers. The resulting CACC fibers were investigated for their biocidal action against E.coli, by using zone inhibition and colonies counting method. Finally, CACC fibers were reduced with sodium borohydride to yield copper nanoparticles-loaded composite fibers and investigated for biocidal action. It was found that CACC fibers possessed both, the fair mechanical strength and antibacterial action. The extent of biocidal action was found to depend upon the amount of Cu(II) loaded and concentration of alginate into cotton- cellulose fibers. The fibers showed higher Cu(II) release in physiological fluid as compared to distilled water. Copper alginate-cotton cellulose (CACC) fibers show fair mechanical strength and release copper ions in the presence of physiological fluid and protein solution. These fibers have great potential to be used as dressing materials.

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Copper (II) ions and copper nanoparticles-loaded chemically modified cotton cellulose fibers with fair antibacterial properties

Journal of Applied Polymer Science ◽

10.1002/app.29890 ◽

2009 ◽

Vol 113 (2) ◽

pp. 757-766 ◽

Cited By ~ 79

Author(s):

Grace Mary ◽

S. K. Bajpai ◽

Navin Chand

Keyword(s):

Copper Nanoparticles ◽

Antibacterial Properties ◽

Cellulose Fibers ◽

Cotton Cellulose ◽

Chemically Modified

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Green Synthesis and Incorporation of Sericin Silver Nanoclusters into Electrospun Ultrafine Cellulose Acetate Fibers for Anti-Bacterial Applications

Polymers ◽

10.3390/polym13091411 ◽

2021 ◽

Vol 13 (9) ◽

pp. 1411

Author(s):

Mujahid Mehdi ◽

Huihui Qiu ◽

Bing Dai ◽

Raja Fahad Qureshi ◽

Sadam Hussain ◽

...

Keyword(s):

Electron Microscopy ◽

Green Synthesis ◽

Cellulose Acetate ◽

Antibacterial Properties ◽

Vital Role ◽

Silver Nanoclusters ◽

Composite Fibers ◽

E Coli ◽

Antibacterial Performance ◽

Field Emission Electron Microscopy

Fiber based antibacterial materials have gained an enormous attraction for the researchers in these days. In this study, a novel Sericin Encapsulated Silver Nanoclusters (sericin-AgNCs) were synthesized through single pot and green synthesis route. Subsequently these sericin-AgNCs were incorporated into ultrafine electrospun cellulose acetate (CA) fibers for assessing the antibacterial performance. The physicochemical properties of sericin-AgNCs/CA composite fibers were investigated by transmission electron microscopy (TEM), field emission electron microscopy (FE-SEM), Fourier transform infrared spectroscopy (FTIR) and wide X-ray diffraction (XRD). The antibacterial properties of sericin-AgNCs/CA composite fibers against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) were systematically evaluated. The results showed that sericin-AgNCs incorporated in ultrafine CA fibers have played a vital role for antibacterial activity. An amount of 0.17 mg/mL sericin-AgNCs to CA fibers showed more than 90% results and elevated upto >99.9% with 1.7 mg/mL of sericin-AgNCs against E. coli. The study indicated that sericin-AgNCs/CA composite confirms an enhanced antibacterial efficiency, which could be used as a promising antibacterial product.

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Microstructure and antibacterial properties of AISI 420 stainless steel implanted by copper ions

Thin Solid Films ◽

10.1016/j.tsf.2005.06.100 ◽

2005 ◽

Vol 492 (1-2) ◽

pp. 93-100 ◽

Cited By ~ 95

Author(s):

Z.G. Dan ◽

H.W. Ni ◽

B.F. Xu ◽

J. Xiong ◽

P.Y. Xiong

Keyword(s):

Stainless Steel ◽

Copper Ions ◽

Antibacterial Properties ◽

Aisi 420

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Preparation and Characterization of Alginate/Polyvinyl Alcohol Composite Fibers Containing Copper Ions

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.652-654.1562 ◽

2013 ◽

Vol 652-654 ◽

pp. 1562-1565 ◽

Cited By ~ 1

Author(s):

Jing Guo ◽

Qian He Chen ◽

Yu Yan Zhang ◽

Yu Mei Gong ◽

Hong Zhang

Keyword(s):

Tensile Strength ◽

Polyvinyl Alcohol ◽

Copper Ions ◽

Fiber Surface ◽

Coagulation Bath ◽

Wet Spinning ◽

Composite Fibers ◽

Pseudoplastic Fluid ◽

Cu Ions

Alginate/polyvinyl alcohol (PVA) composite fibers containing copper ions were prepared by wet spinning. The spinning solution and manufacturing process were researched. The composite fibers were characterized by Tensile Strength Tester, SEM and TGA. This report shows that the spinning solution is a typical kind of pseudoplastic fluid. Adding boric acid to coagulation bath and putting Cu ions into composite fibers can improve the strength. The structure of composite fibers with Cu ions is denser and there are grooves on the fiber surface. In addition, the thermal property of composite fibers is steady.

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Evaluating the antibacterial properties of chitosan fibres embedded with copper ions for wound dressing applications

Journal of Industrial Textiles ◽

10.1177/1528083713483782 ◽

2013 ◽

Vol 44 (2) ◽

pp. 232-244 ◽

Cited By ~ 3

Author(s):

John Barnabas ◽

Mohsen Miraftab ◽

Yimin Qinand ◽

Zhu Changjun

Keyword(s):

Wound Dressing ◽

Copper Ions ◽

Antibacterial Properties

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Preparation of grafted cationic polymer/silver chloride modified cellulose fibers and their antibacterial properties

Journal of Applied Polymer Science ◽

10.1002/app.42092 ◽

2015 ◽

Vol 132 (25) ◽

pp. n/a-n/a ◽

Cited By ~ 3

Author(s):

Xiaoqin Chen ◽

Bojian Hu ◽

Xiaodong Xing ◽

Zuliang Liu ◽

Yan Zuo ◽

...

Keyword(s):

Silver Chloride ◽

Antibacterial Properties ◽

Cellulose Fibers ◽

Cationic Polymer ◽

Modified Cellulose

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Technique for Measuring the Oxygen Index of Fibrous and Powdered Cellulose Derivatives

Journal of Fire Sciences ◽

10.1177/073490418400200307 ◽

1984 ◽

Vol 2 (3) ◽

pp. 248-254 ◽

Cited By ~ 3

Author(s):

Brenda J. Trask ◽

John V. Beninate ◽

George L. Drake

Keyword(s):

Oxygen Index ◽

Cellulose Fibers ◽

Cotton Cellulose ◽

Cellulose Derivatives ◽

Flame Resistance ◽

Fiber Density ◽

Powdered Cellulose ◽

Flammability Test ◽

Experimental Treatments ◽

Derivatives Of

A technique to assess the flame resistance of small quantities of fibrous or powdered derivatives of cotton cellulose was developed. The procedure is an adaptation of the oxygen index (OI) fabric flammability test. Cellulose fibers or powders were pressed into 0.5-g discs, 1 1/4 in. in diameter which were used to measure the OI's in the instrument employed for fabric OI determinations. Comparison of OI's of discs and fabrics representing untreated and conven tionally treated FR cottons resulted in a linear relationship; disc OI values were higher due to higher fiber density and lower accessibility of oxygen to the substrate. Among the experimental treatments of cotton cellulose, OI values of fibrous and powdered celluloses were uniformly low with increasing tritylation, peaked and dropped with increasing tosyl concentration and rose with increas ing mesylation. Some derivatives would be considered flame resistant.

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Silver/chitosan/cellulose fibers foam composites: From synthesis to antibacterial properties

Journal of Colloid and Interface Science ◽

10.1016/j.jcis.2012.10.057 ◽

2013 ◽

Vol 393 ◽

pp. 411-420 ◽

Cited By ~ 55

Author(s):

Eric Guibal ◽

Simon Cambe ◽

Sandrine Bayle ◽

Jean-Marie Taulemesse ◽

Thierry Vincent

Keyword(s):

Antibacterial Properties ◽

Cellulose Fibers

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Copper Complexation Screen Reveals Compounds with Potent Antibiotic Properties against Methicillin-Resistant Staphylococcus aureus

Antimicrobial Agents and Chemotherapy ◽

10.1128/aac.02316-13 ◽

2014 ◽

Vol 58 (7) ◽

pp. 3727-3736 ◽

Cited By ~ 34

Author(s):

Mehri Haeili ◽

Casey Moore ◽

Christopher J. C. Davis ◽

James B. Cochran ◽

Santosh Shah ◽

...

Keyword(s):

Staphylococcus Aureus ◽

High Throughput ◽

Copper Ions ◽

Antibacterial Properties ◽

Rare Event ◽

Innate Immune ◽

Release Mechanism ◽

Immune Functions ◽

Methicillin Resistant ◽

Copper Complexation

ABSTRACTMacrophages take advantage of the antibacterial properties of copper ions in the killing of bacterial intruders. However, despite the importance of copper for innate immune functions, coordinated efforts to exploit copper ions for therapeutic interventions against bacterial infections are not yet in place. Here we report a novel high-throughput screening platform specifically developed for the discovery and characterization of compounds with copper-dependent antibacterial properties toward methicillin-resistantStaphylococcus aureus(MRSA). We detail how one of the identified compounds, glyoxal-bis(N4-methylthiosemicarbazone) (GTSM), exerts its potent strictly copper-dependent antibacterial properties on MRSA. Our data indicate that the activity of the GTSM-copper complex goes beyond the general antibacterial effects of accumulated copper ions and suggest that, in contrast to prevailing opinion, copper complexes can indeed exhibit species- and target-specific activities. Based on experimental evidence, we propose that copper ions impose structural changes upon binding to the otherwise inactive GTSM ligand and transfer antibacterial properties to the chelate. In turn, GTSM determines target specificity and utilizes a redox-sensitive release mechanism through which copper ions are deployed at or in close proximity to a putative target. According to our proof-of-concept screen, copper activation is not a rare event and even extends to already established drugs. Thus, copper-activated compounds could define a novel class of anti-MRSA agents that amplify copper-dependent innate immune functions of the host. To this end, we provide a blueprint for a high-throughput drug screening campaign which considers the antibacterial properties of copper ions at the host-pathogen interface.

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