Poor knowledge of peripheral arterial disease among the Saudi population: A cross-sectional study

Vascular ◽  
2016 ◽  
Vol 25 (1) ◽  
pp. 86-91 ◽  
Author(s):  
Saad Bin Ayeed ◽  
Mohamad A Hussain ◽  
Musaad AlHamzah ◽  
Mohammed Al-Omran

Peripheral arterial disease is a marker of severe atherosclerosis with a significantly higher risk of cardiovascular morbidity and mortality. It is often underdiagnosed and undertreated. Public and patients’ perception of peripheral arterial disease is influenced by their knowledge of the condition. In this study, we aimed to evaluate the Saudi public’s knowledge of peripheral arterial disease and its specific characteristics. We conducted an interview-based cross-sectional survey, and collected data on basic demographics, self-reported peripheral arterial disease awareness, and knowledge of clinical features, risk factors, preventative measures, management strategies, and potential complications of peripheral arterial disease. A total of 866 participants completed the survey (response rate, 94%); two-thirds were females. Only 295 (34%) of the surveyed participants indicated awareness of peripheral arterial disease. Overall peripheral arterial disease knowledge was low among the “peripheral arterial disease aware” group, particularly in the clinical features domain. Age > 40 years, female gender, and higher education were predictors of self-reported awareness of peripheral arterial disease. In conclusion, the Saudi public is largely unaware of peripheral arterial disease. Educational programs are important to address this critical knowledge gap.

2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Janaka Weragoda ◽  
Rohini Seneviratne ◽  
Manuj C. Weerasinghe ◽  
Mandika Wijeyaratne ◽  
Anil Samaranayaka

2021 ◽  
Vol 15 (9) ◽  
pp. 2989-2994
Author(s):  
U. Sivakumar ◽  
Rinku Garg ◽  
Sunita Nighute

Objective: COPD has been recognized not only as a lung but also a systemic disease. Smoking is a major cause of COPD, cardiovascular disease, stroke and peripheral arterial disease (PAD). Methods: This was a cross-sectional study conducted at the Department of Physiology, Santosh Medical College diagnosed with COPD using Spirometry was recruited for the study with a sample size of 130 patients. Results: Of the 130 participants, the mean age was 51.73 years of all COPD patients. Thirty-seven (28.46%) were diagnosed to have PAD. Twenty-five patients (19.23%) were overweight, 10 (7.69%) were obese. All the patients included in the study had history of smoking, including current (n= 67, 51.5%) and former (n= 35, 26.9%) smokers. There was no patient with severe respiratory failure in our study. The most common cardiovascular co-morbidity was hypertension (n= 67, 51.5%), followed by diabetes mellitus (n =28, 21.5%), and dyslipidaemia (n= 35, 26.92%). PAD seen in different stages of COPD stage I –IV were 2.94%, 55.88%, 61.76%, 20.58% respectively. Conclusion: The diagnosis of peripheral arterial disease in COPD is important because this is an entity that limits the patient’s physical activity and impairs their quality of life. Lung function was not associated with PAD in patients with COPD. Abnormal ABI results were associated with a higher prevalence of risk factors and more severe lung disease. Keywords: Peripheral Arterial Disease, Smoking, Chronic Obstructive Pulmonary Disease.


2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Janaka Weragoda ◽  
Manuj C. Weerasinghe ◽  
Rohini Seneviratne ◽  
S. M. Wijeyaratne

2015 ◽  
Vol 47 (11) ◽  
pp. 776-782 ◽  
Author(s):  
Andreas Knudsen ◽  
Catarina Anna Evelina Malmberg ◽  
Andreas Kjær ◽  
Anne-Mette Lebech

2010 ◽  
Vol 104 (07) ◽  
pp. 71-77 ◽  
Author(s):  
Elisabetta Favaretto ◽  
Cristina Legnani ◽  
Michela Cini ◽  
Eleonora Conti ◽  
Alfio Amato ◽  
...  

SummaryFew data are available on thrombophilic risk factors and progression of atherosclerotic peripheral arterial disease (PAD). Thrombophilic alterations can be an aggravating factor when arterial stenoses are present. In a cross-sectional study, we evaluated the presence of the thrombophilic factors fibrinogen, homocysteine, factor (F)VIII, lupus anticoagulant (LAC), FII G20210A, and FV R506Q mutations in 181 patients with PAD at Fontaine’s stage II (claudication), in 110 patients with critical limb ischaemia (CLI), and in 210 controls. Fibrinogen was higher in patients with CLI vs. those with claudication and controls (427.9 ± 10.5 vs. 373.1 ± 5.2 vs. 348.9 ± 7.0 p=0.001, respectively). Homocysteine and FVIII were higher in patients with PAD than in controls, but were similar in patients with CLI and claudication. The prevalence of LAC increased in patients with CLI vs. those with claudication and controls (21.4% vs. 7.8% vs. 5.2% p<0.001, respectively). The prevalence of FII 20210A allele was higher in patients with CLI vs. those with claudication and controls. Using a logistic model, FII G20210A mutation (odds ratio [OR] 19.8, confidence interval [CI] 4.5–87.1, p=0.001), LAC (OR 2.7, CI1.1–6.5, p=0.032), and fibrinogen (OR 1.01, CI 1.00–1.01, p=0.001) were associated with CLI, whereas homocysteine, FVIII, and FV R506Q mutation were not. CLI risk increased according to the number of thrombophilic alterations. In conclusion, altered levels of some important thrombophilic risk factors are independently associated with PAD severity. These data suggest that the presence of two or more thrombophilic risk factors raise the likelihood of PAD being more severe, justifying the need for larger longitudinal studies.


2020 ◽  
Author(s):  
Yumeng Shi ◽  
Lihua Hu ◽  
Minghui Li ◽  
Xiao Huang ◽  
Congcong Ding ◽  
...  

Abstract Background: Previous studies have indicated that serum total bilirubin might play an important role in peripheral artery disease (PAD). However, the effects of different levels of serum total bilirubin (TBiL) on PAD development remain uncertain, and there are limited data in male participants. We aimed to examine the prevalence of PAD and TBiL among Chinese male adults with hypertension.Methods: A total of 5129 hypertensive male subjects aged 27-93 years were included in the current study. The outcome was peripheral arterial disease (PAD), defined as present when the ABI of either side was ≤ 0.90.Results: Of 5129 hypertensive male participants, 194 (3.78%) had PAD, and the mean serum total bilirubin was 15.67 (7.76) μmol/L. Compared to participants in Q2-Q3 of LgTBiL, there was a significantly increased prevalence of PAD for participants in both Q1 (OR, 1.49; 95% CI: 1.04-2.14) and Q4 (OR, 1.70; 95% CI: 1.16-2.48). After adjusting for potential confounders, a nonlinear U-shaped relationship was detected between TBiL and the prevalence of PAD, and the inflection point was calculated to be 1.08 (LgTBiL = 1.08, TBiL = 12.02 μmol/L). The ORs (95% CIs) were 0.11 (0.02, 0.83) on the left side of the inflection point and 5.26 (1.59, 17.38) on the right side of the inflection point. Similar results were found in various subgroups.Conclusions: This cross-sectional study showed that there was a U-shaped curve for the prevalence of PAD with TBiL concentration in Chinese males with hypertension, with a turning point at 12.02 μmol/L.


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