scholarly journals How Much Accuracy of Interstitial Glucose Measurement Is Enough? Is There a Need for New Evidence?

2016 ◽  
Vol 11 (2) ◽  
pp. 296-298 ◽  
Author(s):  
Norbert Hermanns ◽  
Dominic Ehrmann ◽  
Bernhard Kulzer
Keyword(s):  
Blood Glucose ◽  
Point Of Care ◽  
Glucose Monitoring ◽  
Blood Glucose Measurement ◽  
Capillary Blood ◽  
Glucose Measurement ◽  
Capillary Blood Glucose ◽  
Measurement Systems ◽  
Interstitial Glucose ◽  
New Evidence

This analytical comment discusses what standards are needed for the evaluation of the accuracy of glucose measurement systems continuously measuring glucose in the interstitial fluid. Since accuracy standards for continuous glucose monitoring (CGM)/flash glucose monitoring (FGM) systems are currently based on modeling studies or consensus of experts, we raised the question whether non-inferiority trials evaluating the safety and efficacy of CGM/FGM measurements compared to capillary blood glucose measurement with point-of-care devices could help to establish clarity about the needed accuracy standards of CGM/FGM. Such trials could also support the replacement of capillary blood glucose measurements by modern CGM/FGM systems.

Comparison of Glucose Values of Blood Samples Taken in Three Different Ways

2017 ◽  
Vol 28 (4) ◽  
pp. 436-455 ◽  
Author(s):  
Tulay Sagkal Midilli ◽  
Eda Ergın ◽  
Ebru Baysal ◽  
Zeki Arı
Keyword(s):  
Blood Glucose ◽  
Venous Blood ◽  
Middle Finger ◽  
Blood Glucose Measurement ◽  
Capillary Blood ◽  
Glucose Measurement ◽  
Capillary Blood Glucose ◽  
Blood Samples ◽  
Left Hand ◽  
The Right

The purpose of the study was to determine differences and correlations between the blood glucose values of venous blood and the first and second drops of capillary blood samples taken in three different ways. Blood samples were (a) venous blood, (b) the first and second drops of capillary blood from the middle finger of the right hand (only washed with soap and water), and (c) the first and second drops of capillary blood from the middle finger of the left hand (washed with soap and water and cleaned with alcohol). It was concluded that the fasting capillary blood glucose values could be used in place of venous blood glucose values, that only washing the hands with neutral soap and water for 30 s could be sufficient for capillary blood glucose measurement, and that the first or second blood drop from a clean hand could be used for capillary blood glucose measurement.

scholarly journals Glucose Management during Insulinoma Resection Using Real-Time Subcutaneous Continuous Glucose Monitoring

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Yuki Sugiyama ◽  
Chiaki Kiuchi ◽  
Maiko Suzuki ◽  
Yuki Maruyama ◽  
Ryo Wakabayashi ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Real Time ◽  
Continuous Glucose Monitoring ◽  
Glucose Monitoring ◽  
Blood Glucose Measurement ◽  
Glucose Measurement ◽  
Glucose Loading ◽  
Before And After ◽  
Interstitial Glucose ◽  
Glucose Management

Insulinoma is a rare neuroendocrine tumor that causes hypoglycemia due to unregulated insulin secretion. Blood glucose management during insulinoma resection is therefore challenging. We present a case in which real-time subcutaneous continuous glucose monitoring (SCGM) in combination with intermittent blood glucose measurement was used for glycemic control during surgery for insulinoma resection. The SCGM system showed the trends and peak of interstitial glucose in response to glucose loading and the change of interstitial glucose before and after insulinoma resection. These data were helpful for adjusting the glucose infusion; therefore, we think that an SCGM system as a supportive device for glucose monitoring may be useful for glucose management during surgery.

Accuracy of Nurses in Performing Capillary Blood Glucose Monitoring

Diabetes Care ◽  
1989 ◽  
Vol 12 (4) ◽  
pp. 298-301 ◽  
Author(s):  
P. A. Lawrence ◽  
M. C. Dowe ◽  
E. K. Perry ◽  
S. Strong ◽  
G. P. Samsa
Keyword(s):  
Blood Glucose ◽  
Glucose Monitoring ◽  
Capillary Blood ◽  
Blood Glucose Monitoring ◽  
Capillary Blood Glucose

Comparison of two glucose-monitoring systems for use in horses

2022 ◽  
pp. 1-7
Author(s):  
Caitlin E. Malik ◽  
David M. Wong ◽  
Katarzyna A. Dembek ◽  
Katherine E. Wilson
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Concentration ◽  
Point Of Care ◽  
Glucose Monitoring ◽  
Glucose Absorption ◽  
Monitoring Systems ◽  
Oral Glucose ◽  
Clinically Normal ◽  
Freestyle Libre ◽  
Interstitial Glucose

Abstract OBJECTIVE To determine the accuracy of 2 interstitial glucose-monitoring systems (GMSs) for use in horses compared with a point-of-care (POC) glucometer and standard laboratory enzymatic chemistry method (CHEM). ANIMALS 8 clinically normal adult horses. PROCEDURES One of each GMS device (Dexcom G6 and Freestyle Libre 14-day) was placed on each horse, and blood glucose concentration was measured via POC and CHEM at 33 time points and compared with simultaneous GMS readings. An oral glucose absorption test (OGAT) was performed on day 2, and glucose concentrations were measured and compared. RESULTS Glucose concentrations were significantly correlated with one another between all devices on days 1 to 5. Acceptable agreement was observed between Dexcom G6 and Freestyle Libre 14-day when compared with CHEM on days 1, 3, 4, and 5 with a combined mean bias of 10.45 mg/dL and 1.53 mg/dL, respectively. During dextrose-induced hyperglycemia on day 2, mean bias values for Dexcom G6 (10.49 mg/dL) and FreeStyle Libre 14-day (0.34 mg/dL) showed good agreement with CHEM. CLINICAL RELEVANCE Serial blood glucose measurements are used to diagnose or monitor a variety of conditions in equine medicine; advances in near-continuous interstitial glucose monitoring allow for minimally invasive glucose assessment, thereby reducing stress and discomfort to patients. Data from this study support the use of the Dexcom G6 and Freestyle Libre 14-day interstitial glucose-monitoring systems to estimate blood glucose concentrations in horses.

scholarly journals Effect of Body Lotions on Capillary Blood Glucose Measurement – Interference of Hydroquinone-containing Body Lotion with Capillary Glucose Measurement

2018 ◽  
Vol 14 (1) ◽  
pp. 44
Author(s):  
Andrea MA Omengue ◽  
Eugène Sobngwi ◽  
Mesmin Dehayem ◽  
Eric V Balt ◽  
Anne MO Boli ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Glucose Level ◽  
Capillary Blood ◽  
Glucose Measurement ◽  
Capillary Blood Glucose ◽  
Almond Oil ◽  
Patients With Diabetes ◽  
Capillary Glucose ◽  
The Impact ◽  
Sweet Almond

The reliability of capillary blood glucose measurements is tremendously important for patients’ care and follow-up. Some factors independent of glucose control could however affect readings during ambulatory monitoring of capillary glucose levels in patients with diabetes mellitus. We sought to evaluate the impact of three body lotions commonly used in Cameroon on different strata of glycaemia. We explored their influence over time on measured capillary glucose values. We enrolled 16 participants. Eligible individuals were adult patients with diabetes (n=12) stratified into three levels of capillary glucose values (100 ± 40 mg/dL [5.55 ± 2.22 mmol/L], 200 ± 40 mg/dL [11.1 ± 2.22 mmol/L] and 300 ± 40 mg/dL [16.65 ± 2.22 mmol/L]) and normoglycaemic individuals (n=4). We measured capillary blood glucose before application, immediately after, then 5, 30 and 60 minutes after application of sweet almond oil, corticosteroid cream and hydroquinone lotion. The measurements made on impregnated body lotion-permeated fingers were compared to that of a clean finger. We observed a significant increase (delta [95% confidence interval, CI]: 119.5% [77.4–222.1]) of capillary glucose level immediately after administration of hydroquinone-containing body lotion (p<0.001). Capillary glucose values after the use of corticoid cream and sweet almond oil was stable 5, 30 and 60 minutes after application (p=0.875 and p=0.883 respectively). In the case of the hydroquinone-containing body lotion, there was a significant difference between capillary glucose level at 5 minutes (delta [95%CI]: 81.6% [55.3–214.2]; p<0.001), 30 minutes (delta [95%CI]: 71.6% [21.8–134.6]; p<0.001) and 60 minutes (delta [95%CI]: 58.3% [2.8–133.3]; p=0.013) after application compared to the value obtained from the clean finger. We observed from our study that there were significant variations in capillary blood glucose measurements induced by the use of hydroquinone lotion.

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