scholarly journals Effect of Body Lotions on Capillary Blood Glucose Measurement – Interference of Hydroquinone-containing Body Lotion with Capillary Glucose Measurement

2018 ◽  
Vol 14 (1) ◽  
pp. 44
Author(s):  
Andrea MA Omengue ◽  
Eugène Sobngwi ◽  
Mesmin Dehayem ◽  
Eric V Balt ◽  
Anne MO Boli ◽  
...  

The reliability of capillary blood glucose measurements is tremendously important for patients’ care and follow-up. Some factors independent of glucose control could however affect readings during ambulatory monitoring of capillary glucose levels in patients with diabetes mellitus. We sought to evaluate the impact of three body lotions commonly used in Cameroon on different strata of glycaemia. We explored their influence over time on measured capillary glucose values. We enrolled 16 participants. Eligible individuals were adult patients with diabetes (n=12) stratified into three levels of capillary glucose values (100 ± 40 mg/dL [5.55 ± 2.22 mmol/L], 200 ± 40 mg/dL [11.1 ± 2.22 mmol/L] and 300 ± 40 mg/dL [16.65 ± 2.22 mmol/L]) and normoglycaemic individuals (n=4). We measured capillary blood glucose before application, immediately after, then 5, 30 and 60 minutes after application of sweet almond oil, corticosteroid cream and hydroquinone lotion. The measurements made on impregnated body lotion-permeated fingers were compared to that of a clean finger. We observed a significant increase (delta [95% confidence interval, CI]: 119.5% [77.4–222.1]) of capillary glucose level immediately after administration of hydroquinone-containing body lotion (p<0.001). Capillary glucose values after the use of corticoid cream and sweet almond oil was stable 5, 30 and 60 minutes after application (p=0.875 and p=0.883 respectively). In the case of the hydroquinone-containing body lotion, there was a significant difference between capillary glucose level at 5 minutes (delta [95%CI]: 81.6% [55.3–214.2]; p<0.001), 30 minutes (delta [95%CI]: 71.6% [21.8–134.6]; p<0.001) and 60 minutes (delta [95%CI]: 58.3% [2.8–133.3]; p=0.013) after application compared to the value obtained from the clean finger. We observed from our study that there were significant variations in capillary blood glucose measurements induced by the use of hydroquinone lotion.

Jurnal NERS ◽  
2020 ◽  
Vol 14 (2) ◽  
pp. 224
Author(s):  
Muflih Muflih ◽  
Suwarsi Suwarsi ◽  
Fajarina Lathu Asmarani

ABSTRACTIntroduction: The examination of patients with diabetes mellitus (DM) can be done by reviewing their complaints and through a capillary blood glucose level test to determine the value of their Random Blood Glucose Level. QRMA (Quantum Resonance Magnetic Analyzer) is claimed to be able to check the patient’s bodily condition (including blood glucose) with an accuracy of 85%. The purpose of this study was to verify the validity of the QRMA tool and its accuracy by comparing the results of the anamnesis and the examination conducted using the capillary blood glucose test method.Methods: The research method used was a cross-sectional design. The total sample consisted of 44 respondents in the working area of the Community Health Centers in Yogyakarta with the risk factor being blood sugar level instability. The sampling technique used was purposive sampling. The main variable in this study was the value of the blood sugar level measured based on the coefficient value of the QRMA tool and the value of Random Blood Glucose obtained through the capillary blood glucose test.Results: The blood glucose value was not correlated significantly with the coefficient value of QRMA. The value of blood glucose when examined alongside the result of the respondent's anamnesis showed there to be a significant difference. The value of the QRMA coefficient when examined against the results from the history of the respondents showed no significant difference. Linear regression showed that the variables of height, body weight, and IMT had a correlation with the QRMA coefficient value.Conclusion: The QRMA tool was not able to provide a picture of the actual condition of the blood glucose level of the respondents when compared with the results of the anamnesis and the blood glucose value from the capillary blood glucose test. Non-invasive health measurement devices such as QRMA are not used by nurses as a standard for determining the health status of DM patients.


1989 ◽  
Vol 15 (5) ◽  
pp. 435-439 ◽  
Author(s):  
Johnm. Amatruda ◽  
Barbara B. Vallone ◽  
Todd Schuster ◽  
Roberta. Mooney

Precision and accuracy of capillary blood glucose measure ments performed by general staff nurses were assessed before and after a modest reeducation pro gram both with and without the use of reflectance meters. A total of 380 capillary glucose determinations were performed by nurses and the hospital laboratory on the same samples. Prior to reeducation, nurses using meters were more accurate than those reading visually, but no difference was found in precision. Reeducation improved precision equally in both groups while improving accuracy only in the group using meters. While glucose readings with the use of reflectance meters were statistically more accurate than those read visually, the percentage of readings within 10 % and 20 % of the laboratory readings was the same. Thus, the increased accuracy observed with meters may have little practical significance, suggesting that their use might better be based on other consider ations, such as user confidence, convenience, cost, and quality control. Periodic education is, however, an essential component of any quality assurance program.


Author(s):  
Biagio Rapone ◽  
Elisabetta Ferrara ◽  
Luigi Santacroce ◽  
Skender Topi ◽  
Ilaria Converti ◽  
...  

Background: Diabetes is known to be one of the major global epidemic diseases, significantly associated with mortality and morbidity worldwide, conferring a substantial burden to the health care system. The epidemiological transition of this chronic disease tends to worsen unless preventive health strategies are implemented. Appropriate screening devices and standardized methods are crucial to prevent this potentially inauspicious life condition. Currently, the glucometer is the conventional device employed for blood glucose level determination that outputs the blood glucose reading. Glucometer performed in the dental office may be an important device in screening diabetes, so it can be addressed during a periodontal examination. Because gingival blood is a useful source to detect the glucose level, the focus is placed on the opportunity that might provide valuable diagnostic information. This study aimed to compare gingival crevicular blood with finger-stick blood glucose measurements using a self-monitoring glucometer, to evaluate whether gingival crevicular blood could be an alternative to allow accurate chairside glucose testing. Methods: A cross-sectional comparative study was performed among a 31–67-year-old population. Seventy participants with diagnosed type 2 diabetes and seventy healthy subjects, all with positive bleeding on probing, were enrolled. The gingival crevicular blood was collected using a glucometer to estimate the blood glucose level and compared with finger-stick blood glucose level. Results: The mean capillary blood glucose and gingival crevicular blood levels from all samples were, respectively, 160.42 ± 31.31 mg/dL and 161.64 ± 31.56 mg/dL for diabetic participants and 93.51 ± 10.35 mg/dL and 94.47 ± 9.91 mg/dL for healthy patients. In both groups, the difference between gingival crevicular blood and capillary blood glucose levels was non-significant (P < 0.05). The highly significant correlation between capillary blood glucose and gingival crevicular blood (r = 0.9834 for diabetic patients and r = 0.8153 for healthy participants) in both the groups was found. Conclusions: Gingival crevicular blood test was demonstrated as a feasible and useful primary screening tool test for detecting diabetes and for glucose estimation in non-diabetic patients. Use of gingival crevicular blood for screening is an attractive way of identifying a reasonable option of finger-stick blood glucose measurement under the appropriate circumstances. Rapid assessment may precede diagnostic evaluation in diabetic as well as healthy patients with acute severe bleeding. In addition, gingival crevicular blood levels may be needed to monitor the diabetic output.


Medicina ◽  
2021 ◽  
Vol 57 (2) ◽  
pp. 167
Author(s):  
Gyorgy Jermendy ◽  
Agnes Kecskes ◽  
Attila Nagy

Background and Objectives: In patients with diabetes mellitus, hypoglycaemic episodes, especially during night hours, carry a significant risk. Data about the occurrence of nocturnal hypoglycaemia in real-world settings are of clinical importance. The aim of our study was to evaluate the occurrence of nocturnal hypoglycaemia among patients with diabetes using self-monitoring of blood glucose (SMBG) with telemedicine support. Materials and Methods: We retrospectively analysed the central database of an internet-based supportive system between 2010 and 2020 when 8190 SMBG users uploaded nearly 10 million capillary blood glucose values. Nocturnal hypoglycaemia was defined as capillary blood glucose < 3.0 mmol/L measured between 00:00 and 05:59 h. Results: The database contained 914,146 nocturnal blood glucose values from 7298 users; 24,623 (2.7%) glucose values were below the hypoglycaemic threshold and 2363 patients (32.4%) had at least one hypoglycaemic glucose value. Nocturnal hypoglycaemia was more often found in patients with type 1 vs. type 2 diabetes (n = 1890 (80.0%) vs. n = 387 (16.4%), respectively). Hypoglycaemic blood glucose values were most frequently observed in the age group of 10.0–19.9 years (n = 481 (20.4%)). Patients with nocturnal hypoglycaemia were mostly on insulin treatment (1854 (78.5%) patients with 20,727 (84.1%) hypoglycaemic glucose values). Only 356 patients (15.1%) with nocturnal hypoglycaemia performed a retest within 120 min. Within a one-day-long (1440 min) timeframe, the elapsed median time until a retest, yielding a safe blood glucose value (>3.9 mml/L), was 273 min (interquartile range: 157–300 min). Conclusions: Nocturnal hypoglycaemia should be considered as a persisting challenge to antihyperglycaemic treatment in patients living with diabetes. Continuous efforts are needed to improve both antihyperglycaemic treatment and patient education for preventing nocturnal hypoglycaemia, and to act adequately if hypoglycaemic values are detected.


Author(s):  
R P Taylor ◽  
C A Pennock

A comparison has been made between three methods for measuring capillary blood glucose collected on filter paper, including a new method using a Beckman glucose analyser 2. The methods are suitable for use with capillary blood spots collected onto filter paper for monitoring the control of diabetic patients. Their accuracy, precision, and recovery of glucose were similar. Glucose measurement with the Beckman glucose analyser 2 involves elution of the dried blood spots with 2% trichloroacetic acid and injection of a fraction of the eluate into the analyser. The method provides a simple and rapid alternative procedure for laboratories that do not have a heavy workload for this type of assay.


2011 ◽  
Vol 9 (1) ◽  
pp. 14-17
Author(s):  
Rogerio Silicani Ribeiro ◽  
Ricardo Botticini Peres ◽  
Magda Tiemi Yamamoto ◽  
Ana Paula Novaes ◽  
Claudia Regina Laselva ◽  
...  

ABSTRACT Objective: To evaluate the impact of screening hyper and hypoglycemia measured by capillary glycemia and standard monitorization of hyperglycemic patients hospitalized in regular care units of Hospital Israelita Albert Einstein. Methods: The capillary glycemia was measured by the Precision PCx (Abbott) glucosimeter, using the PrecisionWeb (Abbott) software. The detection of hyper and hypoglycemia during the months of May/June were compared to those of March/April in 2009 and to the frequency of the diagnosis of diabetes in 2007. Results: There was an increase in the glycemia screening from 27.7 to 77.5% of hospitalized patients (p < 0.001), of hyperglycemia detection (from 9.3 to 12.2%; p < 0.001) and of hypoglycemia (from 1.5 to 3.3%; p < 0.001) during the months of May/June 2009. According to this action 14 patients for each additional case of hyperglycemia and 26 cases for each case of hypoglycemia were identified. The detection of hyperglycemia was significantly higher (p < 0.001) than the frequency of registered diagnosis related do diabetes in the year of 2007. Conclusions: the adoption of an institutional program of glycemia monitorization improves the detection of hyper and hypoglycemia and glycemia control in hospitalized patients in regular care units.


2021 ◽  
pp. 30-32
Author(s):  
Saunak Nath ◽  
Niladri Sekhar Mukhopadhyay ◽  
Avinab Das

INTRODUCTION: The present study was undertaken to observe the effect of different maintenance uid regimen on intraoperative blood glucose levels in non-diabetic patients undergoing elective major surgery under general anesthesia. AIMS AND OBJECTIVES: This study was conducted to observe the effect of different maintenance uids in intraoperative blood glucose levels of non-diabetic patients undergoing elective major non-cardiac surgery under general anesthesia. MATERIALS AND METHODS: The present study was conducted in the Department of Anesthesiology of Assam Medical College, Dibrugarh for a period of one year. Hospital based observational study. Patients undergoing elective major surgeries at operation theatres of Department of General Surgery of Assam Medical College & Hospital, Dibrugarh. One (1) year from July 2015 to June 2016. RESULT: The mean difference of capillary blood glucose level between baseline and 1.5 hours after intubation for those procedures lasted that long in Group N was 22.87 mg/dl with a 95% condence interval of 103.83-108.61 while in Group R it was 26.82 mg/dl with a 95% condence interval of 108.41-111.59. The mean difference of capillary blood glucose level between baseline and 2 hours after intubation for those procedures lasted that long in Group N was 34.14 mg/dl with a 95% condence interval of 117.29–117.71 while in Group R it was 34.07 with a 95% condence interval of 116.38–118.12. CONCLUSION: This study we can come to a conclusion that though there is a rising trend in change in intraoperative capillary blood glucose level in both the solutions used perioperatively, yet the mean change in intraoperative capillary blood glucose level in non-diabetic patients undergoing major surgeries under general anaesthesia receiving either 0.9% sodium chloride or Ringer's lactate solutions as maintenance uid perioperatively, is comparable, yet needs larger groups of study


2017 ◽  
Vol 28 (4) ◽  
pp. 436-455 ◽  
Author(s):  
Tulay Sagkal Midilli ◽  
Eda Ergın ◽  
Ebru Baysal ◽  
Zeki Arı

The purpose of the study was to determine differences and correlations between the blood glucose values of venous blood and the first and second drops of capillary blood samples taken in three different ways. Blood samples were (a) venous blood, (b) the first and second drops of capillary blood from the middle finger of the right hand (only washed with soap and water), and (c) the first and second drops of capillary blood from the middle finger of the left hand (washed with soap and water and cleaned with alcohol). It was concluded that the fasting capillary blood glucose values could be used in place of venous blood glucose values, that only washing the hands with neutral soap and water for 30 s could be sufficient for capillary blood glucose measurement, and that the first or second blood drop from a clean hand could be used for capillary blood glucose measurement.


Author(s):  
Khaled Aljenaee ◽  
Osamah Hakami ◽  
Colin Davenport ◽  
Gemma Farrell ◽  
Tommy Kyaw Tun ◽  
...  

Summary Measurement of glycated haemoglobin (HbA1c) has been utilised in assessing long-term control of blood glucose in patients with diabetes, as well as diagnosing diabetes and identifying patients at increased risk of developing diabetes in the future. HbA1c reflects the level of blood glucose to which the erythrocyte has been exposed during its lifespan, and there are a number of clinical situations affecting the erythrocyte life span in which HbA1c values may be spuriously high or low and therefore not reflective of the true level of glucose control. In the present case series, we describe the particulars of three patients with diabetes who had spuriously low HbA1c levels as a result of dapsone usage. Furthermore, we discuss the limitations of HbA1c testing and the mechanisms by which it may be affected by dapsone in particular. Learning points: Various conditions and medications can result in falsely low HbA1c. Dapsone can lead to falsely low HbA1c by inducing haemolysis and by forming methaemoglobin. Capillary glucose measurement, urine glucose measurements and fructosamine levels should be used as alternatives to HbA1c for monitoring glycaemic control if it was falsely low or high.


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