Anti-inflammatory Activity of Piper Magnibaccum (Piperaceae)
2008 ◽
Vol 3
(10)
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pp. 1934578X0800301
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Keyword(s):
Anti-inflammatory activity of a crude extract of Piper magnibaccum (Piperaceae) and of compounds isolated from it was established using the TPA-induced mouse ear edema model and an in vitro quantitative lipoxygenase inhibition assay. Five compounds were isolated from P. magnibaccum [β-sitosterol, N-isobutyl-(2 E,4 E)-tetradecadienamide, linoleic acid, 13-(4′, 5′-dimethoxytridecanoyl)piperidine, and piperine]. The light petroleum extract of the plant exhibited significant anti-inflammatory activity in both models. N-isobutyl-(2 E,4 E)-tetradecadienamide showed significant activity, with an IE % value of 70.2 + 5.4 in the TPA-induced mouse ear edema model and 87.2 + 0.11 in the in vitro quantitative lipoxygenase inhibition assay.
2018 ◽
Vol 49
(3)
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pp. 331-336
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2015 ◽
Vol 10
(11)
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pp. 1934578X1501001
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2017 ◽
Vol 45
(2)
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pp. 101-109
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2015 ◽
Vol 2015
◽
pp. 1-7
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2014 ◽
Vol 23
(2)
◽
pp. 426-433
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