scholarly journals Histologic identification of intraocular Cytauxzoon felis in three cats

2018 ◽  
Vol 4 (2) ◽  
pp. 205511691881324
Author(s):  
Jessica Meekins ◽  
Ada G Cino-Ozuna
Keyword(s):  
Blood Vessels ◽  
Clinical Signs ◽  
Case Series ◽  
Clinical Findings ◽  
Ocular Involvement ◽  
State University ◽  
Diagnostic Laboratory ◽  
Uveal Tract ◽  
Cytauxzoon Felis ◽  
Kansas State University

Case series summary A 5-month-old male intact domestic shorthair (DSH) cat (cat 1), a 1-year-old male neutered DSH cat (cat 2) and a 1.5-year-old female spayed DSH cat (cat 3) were submitted for gross necropsy after acute death, with the clinical suspicion of cytauxzoonosis. All three cats displayed signs of rapidly progressive clinical deterioration, including lethargy, anorexia, and hyper- or hypothermia. Cat 1 was euthanized owing to the grave prognosis for survival, whereas cats 2 and 3 were found dead 1–4 days after the onset of clinical signs. Remains were submitted to the Kansas State University Veterinary Diagnostic Laboratory for gross necropsy. In all three cats, general examination findings included icterus of the mucous membranes, multifocal pulmonary parenchymal hemorrhages, and splenic reddening and enlargement. Histologic examination revealed macrophages laden with protozoal schizonts diffusely distributed within blood vessels and vascular spaces of all affected organs, including the blood vessels of the uveal tract. The ciliary body within the anterior uveal tract was most affected. Relevance and novel information This is the first description of cytauxzoonosis affecting the eyes of infected cats. This report confirms involvement of ocular blood vessels similar to the classic lesions of the lungs, spleen and liver. In cats presenting with a history and clinical findings suggestive of cytauxzoonosis, complete ophthalmic examination is indicated to confirm or rule out ocular involvement.

scholarly journals Clinical features of cats with aqueous tear deficiency: a retrospective case series of 10 patients (17 eyes)

2018 ◽  
Vol 21 (10) ◽  
pp. 944-950 ◽  
Author(s):  
Lisa K Uhl ◽  
Akihiko Saito ◽  
Hiroko Iwashita ◽  
David J Maggs ◽  
Jonathan P Mochel ◽  
...  
Keyword(s):  
Clinical Features ◽  
Ocular Surface ◽  
Clinical Signs ◽  
Case Series ◽  
Reference Interval ◽  
Clinical Findings ◽  
Response To Therapy ◽  
Ocular Surface Disease ◽  
Retrospective Case ◽  
Schirmer Tear Test

Objectives The aim of this study was to describe the clinical findings, diagnostic test results and response to therapy of cats with Schirmer tear test 1 (STT-1) values below the reference interval. Methods The medical records of three institutions were searched for cats with ocular surface disease and STT-1 values <9 mm/min, confirmed at two or more separate visits. Results Ten cats (17 eyes) were included. The mean ± SD (range) age and STT-1 values in affected eye(s) were 6.1 ± 5.7 (0.2–16) years and 2.4 ± 3.1 (0–8) mm/min, respectively. Concurrent ocular surface disease was bilateral in 5/10 cats. Clinical signs included conjunctivitis (14/17 eyes), corneal ulceration (6/17 eyes), non-ulcerative keratitis (4/17 eyes), symblepharon (4/17 eyes), eosinophilic keratitis (3/17 eyes), corneal sequestrum (3/17 eyes), corneal fibrosis (2/17 eyes) and meibomitis (2/17 eyes). Management included: topically applied lacrimomimetics, antiviral drugs, corticosteroids or immunomodulatory drugs; orally administered famciclovir; or surgical procedures, in various combinations. Response to therapy (defined as an increase in STT-1 value of ⩾5 mm/min) was transient (seen at a single reassessment) in 65% of eyes and sustained (seen at ⩾2 consecutive reassessments) in 18% of eyes. Conclusions and relevance Clinical features seen in cats with low STT-1 values are described, although the association between aqueous deficiency and the reported ocular changes is unknown at this time. We encourage clinicians to assess the tear film in cats with ocular surface disease, and initiate therapy with lacrimomimetics if STT-1 values are repeatedly below normal. Such information will further define aqueous tear deficiency in cats, providing a better understanding of disease prevalence, pathogenesis and treatment.

scholarly journals Clinical Coccidiosis in a Boar Stud

2003 ◽  
Vol 15 (4) ◽  
pp. 387-389 ◽  
Author(s):  
Michael J. Yaeger ◽  
Andrew Holtcamp ◽  
Julie A. Jarvinen
Keyword(s):  
Small Intestine ◽  
Antibiotic Therapy ◽  
Laboratory Tests ◽  
Clinical Course ◽  
Clinical Signs ◽  
State University ◽  
Iowa State University ◽  
Diagnostic Laboratory ◽  
Fecal Samples ◽  
History Of

This report describes an outbreak of coccidiosis in a boar stud. A live, untreated, adult boar with a history of diarrhea was submitted to the Iowa State University Veterinary Diagnostic Laboratory, Ames, IA. For a 3-month period, approximately 40% of the boars in this stud had developed gray to brown diarrhea that lasted 1–3 days. Affected boars did not lose condition, and antibiotic therapy did not appear to affect the clinical course of the disease. At necropsy, the distal ileum was palpably thickened and covered by a thick, yellow-green, fibrinous exudate. Microscopic changes in the ileum consisted of an erosive enteritis associated with the presence of numerous coccidia within mid to superficial villus enterocytes. The mucosa was covered by a fibrinous exudate admixed with numerous nonsporulated coccidian oocysts. A light growth of Salmonella enterica serovar Derby was isolated from the small intestine of this animal, but laboratory tests were negative for Lawsonia and Brachyspira spp. Individual or paired fecal samples were obtained from 6 additional boars experiencing similar clinical signs. Numerous Eimeria spinosa oocysts were identified in these samples. Neither Salmonella nor Brachyspira spp. were cultured from submitted fecal samples. Necropsy of a live boar and examination of feces from 6 additional animals confirmed that the mild, sporadic, transient diarrhea in this boar stud was due to coccidiosis.

Tuberculosis Uveitis: Clinical Findings, Diagnosis, and Treatment

2019 ◽  
pp. 290-299
Keyword(s):  
Imaging Techniques ◽  
Clinical Signs ◽  
Clinical Manifestations ◽  
Clinical Findings ◽  
Classification Systems ◽  
Ocular Involvement ◽  
New Classification ◽  
Duration Of Treatment ◽  
High Index Of Suspicion ◽  
Microbiological Confirmation

Tuberculosis (TB) is a chronic systemic infectious disease that primarily affects lungs but may also affect extrapulmonary organs including the eye. TB uveitis is the most common presentation of ocular involvement and has variable clinical features. Active systemic TB may not always accompany the ocular disease. A high index of suspicion based on typical clinical manifestations is important in diagnosis. In recent years new classification systems including, clinical signs, microbiological confirmation, immunological evidence, and imaging techniques have been suggested for diagnosing intraocular TB. Longer duration of treatment with ATT results in good clinical response.

scholarly journals Detection of Mycobacterium avium Subspecies Paratuberculosis from Intestinal and Nodal Tissue of Dogs and Cats

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Kate S. KuKanich ◽  
Javier Vinasco ◽  
H. Morgan Scott
Keyword(s):  
Gastrointestinal Disease ◽  
Mycobacterium Avium Subspecies Paratuberculosis ◽  
Clinical Signs ◽  
Rural Environment ◽  
State University ◽  
Tissue Samples ◽  
Gastrointestinal Pathology ◽  
Gastrointestinal Inflammation ◽  
Kansas State University ◽  
Nodal Tissue

Objective. To determine prevalence of MAP in intestinal and nodal tissue from dogs and cats at necropsy at Kansas State University and to determine if an association existed between presence of MAP and gastrointestinal inflammation, clinical signs, or rural exposure. Procedures. Tissue samples were collected from the duodenum, ileum, and mesenteric and colic nodes of adult dogs (73) and cats (37) undergoing necropsy for various reasons. DNA was extracted and analyzed for insertion sequence 900 using nested PCR. Positive samples were confirmed with DNA sequencing. An online mapping system was used to determine if patients lived in an urban or rural environment based on the home address. Medical records were reviewed for clinical signs and histological findings at necropsy. Results. MAP was identified from 3/73 (4.1%) dogs and 3/37 (8.1%) cats. There was no documented association between presence of MAP and identification of histologic-confirmed gastrointestinal inflammation, gastrointestinal clinical signs, or exposure to a rural environment. Conclusion and Clinical Relevance. MAP-specific DNA can be identified within the intestinal and nodal tissue of dogs and cats that do not have pathological lesions or clinical signs consistent with gastrointestinal disease. The significance of this organism’s presence without associated gastrointestinal pathology is unknown.

scholarly journals Prevalence of erosive wear lesions in Gastro-Esophageal Reflux Disease patients – A case series

2021 ◽  
Vol 28 ◽  
pp. 1-7
Author(s):  
Prema Sukumaran ◽  
Siti Nurshakina Abdul Kamar ◽  
Nur Azwa Nadia M Zalani ◽  
Divya Nambiar ◽  
Rathna Devi Vaithilingam ◽  
...  
Keyword(s):  
Reflux Disease ◽  
Clinical Signs ◽  
Case Series ◽  
Erosive Wear ◽  
Clinical Findings ◽  
Esophageal Reflux ◽  
Anterior Teeth ◽  
Dental Practitioners ◽  
Tooth Surfaces ◽  
Mandibular Teeth

Extra esophageal manifestation of Gastro-esophageal reflux disease (GERD) include erosive wear dental lesions. Early erosive wear lesions in this group of patients can be easily missed as they are accompanied by few clinical signs and hardly any symptoms. This case series aims to report the prevalence and severity of erosive wear lesions amongst a sample of GERD patients in Malaysia. Eleven subjects with well characterized GERD, diagnosed based on modified Reflux Disease Questionnaire (RDQ) or via endoscopy, were included in this case series. A standardized intra oral clinical examination was performed to assess presence and severity of erosive wear lesions on tooth surfaces using Basic Erosive Wear Examination (BEWE) index. Majority of BEWE score 1 lesions were distributed in maxillary anterior teeth, followed by maxillary posterior and mandibular teeth. BEWE score 2 lesions were most prevalent in maxillary anterior teeth and there were no BEWE score 3 lesions observed. Based on the clinical findings, more erosive wear lesions were found on the buccal surfaces of maxillary and mandibular teeth in GERD patients. This case series further confirms the link between GERD and erosive wear lesions. The authors would like to highlight the need for both medical and dental practitioners to be aware of early clinical presentations of GERD and erosive wear lesions. Early diagnoses allow for intervention and conservative management of these conditions.

scholarly journals PSI-5 Effects of rest period prior to processing on anthelmintic response during the receiving period in feedlot heifers

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 225-226
Author(s):  
Nicole Stafford ◽  
A J Tarpoff ◽  
Miles Theurer ◽  
Tom Jones ◽  
Cassandra K Jones
Keyword(s):  
Animal Health ◽  
Rest Period ◽  
Parasite Prevalence ◽  
Feedlot Cattle ◽  
State University ◽  
Diagnostic Laboratory ◽  
Fecal Samples ◽  
Randomized Design ◽  
Kansas State University ◽  
The Impact

Abstract A major stressor affecting feedlot cattle performance is transportation. Knowing when to process cattle and how much rest to provide prior to processing may improve cattle health and response to processing, such as anthelmintic administration. The goal of this project was to determine the impact of time of rest prior to initial processing on parasite prevalence during the receiving period. Eighty mixed-breed heifers (250±4.2 kg BW) were purchased at live auction in Oklahoma City, OK and transported to the Kansas State University Beef Cattle Research Center in Manhattan. Heifers were allotted in a completely randomized design to one of four treatments processed at 0, 6, 24, or 48 hours after arrival. At processing (d 0), fecal samples were collected, and cattle were subcutaneously injected with 1.0 ml/50 kg BW moxidectin (Cydectin®, Bayer Animal Health, Shawnee Mission, KS) and orally dosed with 1.0 mL/50 kg BW oxfendazole (Synanthic®, Boehringer Ingelheim, St. Joseph, MO). Fecal samples were collected again on d 14. Fecal samples were analyzed by the Kansas State University Veterinary Diagnostic Laboratory for qualitative and quantitative fecal float. Time of processing did not impact (P &gt; 0.05) any measured response criteria. On d 0, there was a high prevalence of fecal parasites, which was significantly reduced by d 14 (94.5% vs. 23.1% of cattle with detected fecal parasites on d 0 vs. 14, respectively). On d 0, semi-quantitative density showed the highest concentration of strongyle and eimeria parasites, which were significantly reduced (P &lt; 0.05) by d 14 (315 and 155 vs. 2 and 6.5 eggs/g of feces detected for strongyle vs. eimeria, respectively). In summary, time of rest prior to processing had no detected impact on anthelmintic response, but the dual injection/oral protocol used in this experiment was highly effective at reducing parasite levels within 2 weeks of administration.

Ultrastructural Studies of Bovine Respiratory Disease Complex

1975 ◽  
Vol 33 ◽  
pp. 428-429
Author(s):  
James C.S. Kim
Keyword(s):  
Michigan State University ◽  
State University ◽  
Diagnostic Laboratory ◽  
Ultrastructural Studies ◽  
Bovine Respiratory Diseases ◽  
Etiologic Agents ◽  
Diagnostic Difficulties ◽  
The Subject ◽  
Capillary Walls ◽  
Alveolar Capillary

Bovine respiratory diseases cause serious economic loses and present diagnostic difficulties due to the variety of etiologic agents, predisposing conditions, parasites, viruses, bacteria and mycoplasma, and may be multiple or complicated. Several agents which have been isolated from the abnormal lungs are still the subject of controversy and uncertainty. These include adenoviruses, rhinoviruses, syncytial viruses, herpesviruses, picornaviruses, mycoplasma, chlamydiae and Haemophilus somnus.Previously, we have studied four typical cases of bovine pneumonia obtained from the Michigan State University Veterinary Diagnostic Laboratory to elucidate this complex syndrome by electron microscopy. More recently, additional cases examined reveal electron opaque immune deposits which were demonstrable on the alveolar capillary walls, laminae of alveolar capillaries, subenthothelium and interstitium in four out of 10 cases. In other tissue collected, unlike other previous studies, bacterial organisms have been found in association with acute suppurative bronchopneumonia.

Student and Institutional Achievements during an OIE Veterinary Education Twinning Project Collaboration between Sokoine University of Agriculture and Kansas State University

2020 ◽  
pp. e20190121
Author(s):  
Tesfaalem Tekleghiorghis Sebhatu ◽  
Rudovick Kazwala ◽  
Derek Mosier ◽  
Maulilio Kipanyula ◽  
Amandus Muhairwa ◽  
...  
Keyword(s):  
State University ◽  
Veterinary Education ◽  
Kansas State University

scholarly journals Cultivating Textbook Alternatives From the Ground Up: One Public University’s Sustainable Model for Open and Alternative Educational Resource Proliferation

2017 ◽  
Vol 18 (4) ◽  
Author(s):  
Jonathan Lashley ◽  
Rebel Cummings-Sauls ◽  
Andrew B. Bennett ◽  
Brian L. Lindshield
Keyword(s):  
Public Universities ◽  
Institutional Support ◽  
Educational Resources ◽  
Educational Resource ◽  
Faculty Participation ◽  
State University ◽  
Methodical Approach ◽  
The Creation ◽  
Kansas State University ◽  
Open Materials

<p class="3">This note from the field reviews the sustainability of an institution-wide program for adopting and adapting open and alternative educational resources (OAER) at Kansas State University (K-State). Developed in consult of open textbook initiatives at other institutions and modified around the needs and expectations of K-State students and faculty, this initiative proposes a sustainable means of incentivizing faculty participation via institutional support, encouraging the creation and maintenance of OAER through recurring funding, promoting innovative realizations of “educational resources” beyond traditional textbooks, and rallying faculty participation in adopting increasingly open textbook alternatives. The history and resulting structure of the initiative raise certain recommendations for how public universities may sustainably offset student textbook costs while also empowering the pedagogies of educators via a more methodical approach to adopting open materials.</p>

scholarly journals Atypical Clinical Presentation of Laryngopharyngeal Reflux: A 5-Year Case Series

2021 ◽  
Vol 10 (11) ◽  
pp. 2439
Author(s):  
Jerome R. Lechien ◽  
Stéphane Hans ◽  
Francois Bobin ◽  
Christian Calvo-Henriquez ◽  
Sven Saussez ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Laryngopharyngeal Reflux ◽  
Case Series ◽  
Clinical Findings ◽  
Aerodigestive Tract ◽  
Common Disease ◽  
Upper Aerodigestive Tract ◽  
Suppurative Otitis Media ◽  
Adequate Treatment ◽  
Atypical Clinical Presentation

Background: Laryngopharyngeal reflux (LPR) is a common disease in otolaryngology characterized by an inflammatory reaction of the mucosa of the upper aerodigestive tract caused by digestive refluxate enzymes. LPR has been identified as the etiological or favoring factor of laryngeal, oral, sinonasal, or otological diseases. In this case series, we reported the atypical clinical presentation of LPR in patients presenting in our clinic with reflux. Methods: A retrospective medical chart review of 351 patients with LPR treated in the European Reflux Clinic in Brussels, Poitiers and Paris was performed. In order to be included, patients had to report an atypical clinical presentation of LPR, consisting of symptoms or findings that are not described in the reflux symptom score and reflux sign assessment. The LPR diagnosis was confirmed with a 24 h hypopharyngeal-esophageal impedance pH study, and patients were treated with a combination of diet, proton pump inhibitors, and alginates. The atypical symptoms or findings had to be resolved from pre- to posttreatment. Results: From 2017 to 2021, 21 patients with atypical LPR were treated in our center. The clinical presentation consisted of recurrent aphthosis or burning mouth (N = 9), recurrent burps and abdominal disorders (N = 2), posterior nasal obstruction (N = 2), recurrent acute suppurative otitis media (N = 2), severe vocal fold dysplasia (N = 2), and recurrent acute rhinopharyngitis (N = 1), tearing (N = 1), aspirations (N = 1), or tracheobronchitis (N = 1). Abnormal upper aerodigestive tract reflux events were identified in all of these patients. Atypical clinical findings resolved and did not recur after an adequate antireflux treatment. Conclusion: LPR may present with various clinical presentations, including mouth, eye, tracheobronchial, nasal, or laryngeal findings, which may all regress with adequate treatment. Future studies are needed to better specify the relationship between LPR and these atypical findings through analyses identifying gastroduodenal enzymes in the inflamed tissue.

Sign in / Sign up

Export Citation Format

Share Document