scholarly journals Post-concussion states: How do we improve our patients’ outcomes? An Australian perspective

2020 ◽  
Vol 4 ◽  
pp. 205970022096031
Author(s):  
Elizabeth Thomas ◽  
Melinda Fitzgerald ◽  
Gill Cowen

There is limited data surrounding incidence and prevalence of concussion and the resulting post-concussion states. This creates difficulty when investigating ways to optimise patient management. It is proposed that a registry of patients presenting with symptoms and signs after a concussion, as part of a large scale TBI registry across Australia, would provide a starting point for future research with a view to improving the outcomes of patients experiencing symptoms and signs after concussion.

Author(s):  
Jana Groß Ophoff ◽  
Sandra Schladitz ◽  
Markus Wirtz

The ability to purposefully access, reflect on, and use evidence from educational research (Educational Research Literacy, ERL) are key competencies of future professionals in educational practice. Based on the conceptual framework presented in this paper, a test instrument was developed to assess ERL, consisting of the competence facets Information Literacy, Statistical Literacy, and Evidence-based Reasoning. This contribution aims to delve deeper into the question of whether Educational Science students differ in their overall ERL proficiency depending on their study program and university. This comparison is based on a large-scale study of 1,213 Educational Science students (Teacher Training and Educational Studies) at six German universities in the winter semester of 2012/13 and in the summer semester of 2013. The results indicate that students seem to profit from their studies at the different universities. Moreover, the ERL competence facets differentiate to some extent between universities and degree programs, which can serve as the starting point for curricular quality development measures. Subsequently, the results are critically discussed, and the desiderata for future research are stated, e.g., the identification of predictors that cause the reported differences.


Facilities ◽  
2018 ◽  
Vol 36 (11/12) ◽  
pp. 546-570
Author(s):  
Abdelkrim Benammar ◽  
Karima Anouche ◽  
Hasnia Lesgaa ◽  
Yamina Hamza Cherif

PurposeThis paper aims to examine the impact of an open-plan office (OPO) space organisation on a user’s attitude in the Algerian context; more specifically, it investigates gender differences in the occupants’ perception of such working environment. It, principally, aims to explore the employees’ reaction towards OPO and sees how much such local office type complies with indoor environment quality (IEQ) and psychological comfort.Design/methodology/approachThe theoretical framework of the study is mainly related to environmental psychology referring to the interaction between users and their environment. Post-occupancy evaluation was carried out using exploratory study and questionnaires, followed by statistical analyses. It was performed on a large-scale sample of employees (296 employees) working in recently built OPO situated in Oran (Algeria).FindingsFundamentally, women appear to show more concern regarding comfort. They do not show much reluctance to be mixed with men in a large office space as opposed to more conservative reaction towards mixing up in outdoor public space environment. As for environmental factors (IEQ), indicators have shown the inadequacy of most buildings in terms of thermal, light or noise comfort. The study has also revealed that a majority of users recognise the professional advantages of the OPO, although it is suggested that their preferred type would be the individual office.Originality/valueThe paper provides a concise starting point for future research interested in developing Algerian context OPO design in terms of both indoor environmental and psychological comfort.


2019 ◽  
Vol 10 (1) ◽  
pp. 39-57 ◽  
Author(s):  
Jinsu Byun ◽  
Becca Leopkey ◽  
Dana Ellis

PurposeThe purpose of this paper is to present a theoretical analysis that examines joint bids that unite multiple cities or nations in a bid for hosting international large-scale sport events from the perspective of strategic alliances.Design/methodology/approachUsing previous strategic alliance research and examples of joint sport event bids, this study discusses how joint event bids can be understood as strategic alliances.FindingsMotivations of bidders and driving forces behind the formation of joint bids are identified and analyzed. By integrating theories used in the area of strategic alliances, this study provides an agenda for moving research on joint bids forward as the practice continues to expand.Originality/valueAs a conceptual paper, the findings of this study can be a starting point for future research not only on joint bids but also on inter-organizational relationships in the context of sport event bidding.


2021 ◽  
Vol 13 (17) ◽  
pp. 9813
Author(s):  
Ju Young Lee ◽  
Sandra Waddock

The challenges that are associated with the 17 United Nations sustainable development goals are wickedly complex and interconnected in nature. Because they require transformational changes at the systems level, the pace of change has, so far, been nowhere near fast enough to meet the goals by 2030. In this paper, we analyze the catalytic actions of a novel form of organizing that could potentially facilitate the timely achievement of transformational aspirations such as the SDGs: the transformation catalyst (TC). By identifying 27 TCs and analyzing their vision, mission, values, and their practices represented on their websites, we elaborate the following four key ways that TCs are distinctive from other entities, and therefore potentially more capable of facilitating transformational changes at the systems level: (1) TCs have transformation agendas that target systems-level solutions to bring about large-scale and fundamental changes in the relevant system(s), as opposed to more incremental or fragmented approaches; (2) TCs engage in catalytic actions, such as connecting, cohering, and amplifying the work of partners and collaborators; (3) TCs clearly acknowledge the current status quo, attributions, and urgency (i.e., sensemaking) of the issues on which they focus; and finally, (4) TCs embody systems orientation. In exploring how TCs work, we hope to build a solid conceptual framework for understanding the nature of transformative catalytic action on societal issues, and consolidate our understanding of what elements are needed if TCs are to work, providing a starting point for future research.


2017 ◽  
Vol 5 (1) ◽  
pp. 70-82
Author(s):  
Soumi Paul ◽  
Paola Peretti ◽  
Saroj Kumar Datta

Building customer relationships and customer equity is the prime concern in today’s business decisions. The emergence of internet, especially social media like Facebook and Twitter, changed traditional marketing thought to a great extent. The importance of customer orientation is reflected in the axiom, “The customer is the king”. A good number of organizations are engaging customers in their new product development activities via social media platforms. Co-creation, a new perspective in which customers are active co-creators of the products they buy and use, is currently challenging the traditional paradigm. The concept of co-creation involving the customer’s knowledge, creativity and judgment to generate value is considered not only an upcoming trend that introduces new products or services but also fitting their need and increasing value for money. Knowledge and innovation are inseparable. Knowledge management competencies and capacities are essential to any organization that aspires to be distinguished and innovative. The present work is an attempt to identify the change in value creation procedure along with one area of business, where co-creation can return significant dividends. It is on extending the brand or brand category through brand extension or line extension. This article, through an in depth literature review analysis, identifies the changes in every perspective of this paradigm shift and it presents a conceptual model of company-customer-brand-based co-creation activity via social media. The main objective is offering an agenda for future research of this emerging trend and ensuring the way to move from theory to practice. The paper acts as a proposal; it allows the organization to go for this change in a large scale and obtain early feedback on the idea presented. 


2019 ◽  
Vol 22 (5) ◽  
pp. 346-354
Author(s):  
Yan A. Ivanenkov ◽  
Renat S. Yamidanov ◽  
Ilya A. Osterman ◽  
Petr V. Sergiev ◽  
Vladimir A. Aladinskiy ◽  
...  

Aim and Objective: Antibiotic resistance is a serious constraint to the development of new effective antibacterials. Therefore, the discovery of the new antibacterials remains one of the main challenges in modern medicinal chemistry. This study was undertaken to identify novel molecules with antibacterial activity. Materials and Methods: Using our unique double-reporter system, in-house large-scale HTS campaign was conducted for the identification of antibacterial potency of small-molecule compounds. The construction allows us to visually assess the underlying mechanism of action. After the initial HTS and rescreen procedure, luciferase assay, C14-test, determination of MIC value and PrestoBlue test were carried out. Results: HTS rounds and rescreen campaign have revealed the antibacterial activity of a series of Nsubstituted triazolo-azetidines and their isosteric derivatives that has not been reported previously. Primary hit-molecule demonstrated a MIC value of 12.5 µg/mL against E. coli Δ tolC with signs of translation blockage and no SOS-response. Translation inhibition (26%, luciferase assay) was achieved at high concentrations up to 160 µg/mL, while no activity was found using C14-test. The compound did not demonstrate cytotoxicity in the PrestoBlue assay against a panel of eukaryotic cells. Within a series of direct structural analogues bearing the same or bioisosteric scaffold, compound 2 was found to have an improved antibacterial potency (MIC=6.25 µg/mL) close to Erythromycin (MIC=2.5-5 µg/mL) against the same strain. In contrast to the parent hit, this compound was more active and selective, and provided a robust IP position. Conclusion: N-substituted triazolo-azetidine scaffold may be used as a versatile starting point for the development of novel active and selective antibacterial compounds.


2019 ◽  
Vol 15 (1) ◽  
pp. 54-56
Author(s):  
Stelina Alkagiet ◽  
Konstantinos Tziomalos

Primary aldosteronism (PA) is not only a leading cause of secondary and resistant hypertension, but is also quite frequent in unselected hypertensive patients. Moreover, PA is associated with increased cardiovascular risk, which is disproportionate to BP levels. In addition, timely diagnosis of PA and prompt initiation of treatment attenuate this increased risk. On the other hand, there are limited data regarding the usefulness of screening for PA in all asymptomatic or normokalemic hypertensive patients. More importantly, until now, no well-organized, large-scale, prospective, randomized controlled trial has proved the effectiveness of screening for PA for improving clinical outcome. Accordingly, until more relevant data are available, screening for PA should be considered in hypertensive patients with spontaneous or diuretic-induced hypokalemia as well as in those with resistant hypertension. However, screening for PA in all hypertensive patients cannot be currently recommended.


Author(s):  
Xu Pei-Zhen ◽  
Lu Yong-Geng ◽  
Cao Xi-Min

Background: Over the past few years, the subsynchronous oscillation (SSO) caused by the grid-connected wind farm had a bad influence on the stable operation of the system and has now become a bottleneck factor restricting the efficient utilization of wind power. How to mitigate and suppress the phenomenon of SSO of wind farms has become the focus of power system research. Methods: This paper first analyzes the SSO of different types of wind turbines, including squirrelcage induction generator based wind turbine (SCIG-WT), permanent magnet synchronous generator- based wind turbine (PMSG-WT), and doubly-fed induction generator based wind turbine (DFIG-WT). Then, the mechanisms of different types of SSO are proposed with the aim to better understand SSO in large-scale wind integrated power systems, and the main analytical methods suitable for studying the SSO of wind farms are summarized. Results: On the basis of results, using additional damping control suppression methods to solve SSO caused by the flexible power transmission devices and the wind turbine converter is recommended. Conclusion: The current development direction of the SSO of large-scale wind farm grid-connected systems is summarized and the current challenges and recommendations for future research and development are discussed.


Author(s):  
Matilda A. Haas ◽  
Harriet Teare ◽  
Megan Prictor ◽  
Gabi Ceregra ◽  
Miranda E. Vidgen ◽  
...  

AbstractThe complexities of the informed consent process for participating in research in genomic medicine are well-documented. Inspired by the potential for Dynamic Consent to increase participant choice and autonomy in decision-making, as well as the opportunities for ongoing participant engagement it affords, we wanted to trial Dynamic Consent and to do so developed our own web-based application (web app) called CTRL (control). This paper documents the design and development of CTRL, for use in the Australian Genomics study: a health services research project building evidence to inform the integration of genomic medicine into mainstream healthcare. Australian Genomics brought together a multi-disciplinary team to develop CTRL. The design and development process considered user experience; security and privacy; the application of international standards in data sharing; IT, operational and ethical issues. The CTRL tool is now being offered to participants in the study, who can use CTRL to keep personal and contact details up to date; make consent choices (including indicate preferences for return of results and future research use of biological samples, genomic and health data); follow their progress through the study; complete surveys, contact the researchers and access study news and information. While there are remaining challenges to implementing Dynamic Consent in genomic research, this study demonstrates the feasibility of building such a tool, and its ongoing use will provide evidence about the value of Dynamic Consent in large-scale genomic research programs.


Electronics ◽  
2021 ◽  
Vol 10 (14) ◽  
pp. 1670
Author(s):  
Waheeb Abu-Ulbeh ◽  
Maryam Altalhi ◽  
Laith Abualigah ◽  
Abdulwahab Ali Almazroi ◽  
Putra Sumari ◽  
...  

Cyberstalking is a growing anti-social problem being transformed on a large scale and in various forms. Cyberstalking detection has become increasingly popular in recent years and has technically been investigated by many researchers. However, cyberstalking victimization, an essential part of cyberstalking, has empirically received less attention from the paper community. This paper attempts to address this gap and develop a model to understand and estimate the prevalence of cyberstalking victimization. The model of this paper is produced using routine activities and lifestyle exposure theories and includes eight hypotheses. The data of this paper is collected from the 757 respondents in Jordanian universities. This review paper utilizes a quantitative approach and uses structural equation modeling for data analysis. The results revealed a modest prevalence range is more dependent on the cyberstalking type. The results also indicated that proximity to motivated offenders, suitable targets, and digital guardians significantly influences cyberstalking victimization. The outcome from moderation hypothesis testing demonstrated that age and residence have a significant effect on cyberstalking victimization. The proposed model is an essential element for assessing cyberstalking victimization among societies, which provides a valuable understanding of the prevalence of cyberstalking victimization. This can assist the researchers and practitioners for future research in the context of cyberstalking victimization.


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