Painful catamenial vulvar lesions misleading gynecologist

Endometriosis usually presents as cyclical pain in the pelvis but may also present as painful cutaneous lesions. Many diseases may mimic hidradenitis suppurativa (HS) since HS, a chronic inflammatory painful skin disease, is a clinical diagnosis. A 32-year-old woman presented with painful lumps on her vulva and groin accompanied with bloody discharge during menstruation. She was followed up with preliminary diagnosis of endometriosis. Previous excision without definitive diagnosis resulted in temporary relief. She was prescribed oral contraceptive pills that alleviated her symptoms but quitted due to headache. Surgical excision was performed for definitive diagnosis and therapeutic relief. Pathology report revealed HS. She was prescribed oral doxycycline. She responded well to the therapy and has symptom-free for the last 2 years. She delivered one healthy girl via cesarian section 2 years after the treatment. Endometriosis and HS should be included in the differential diagnosis when women present with menstrual painful lesions around external genitalia for diagnosis and treatment.

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The Role of Oral Contraceptive Pills in Hidradenitis Suppurativa: A Cohort Study

Life ◽

10.3390/life11070697 ◽

2021 ◽

Vol 11 (7) ◽

pp. 697

Author(s):

Trinidad Montero-Vilchez ◽

Andrea Valenzuela-Amigo ◽

Carlos Cuenca-Barrales ◽

Salvador Arias-Santiago ◽

Ana Leyva-García ◽

...

Keyword(s):

Oral Contraceptive ◽

Menstrual Cycle ◽

Hidradenitis Suppurativa ◽

Prospective Observational Study ◽

Disease Duration ◽

Concomitant Therapy ◽

Oral Contraceptive Pills ◽

Contraceptive Pills ◽

First Time

There is a need to establish the role of antiandrogens as an alternative or concomitant therapy for hidradenitis suppurativa (HS). Thus, the objectives of this study are (1) to assess the effectiveness of oral contraceptive pills (OCPs) at week 12 in HS women, and (2) to describe the clinical profile of patients receiving oral contraceptive pills (OCPs). A prospective observational study was designed. This study included 100 participants, 50 women with HS who started OCPs for the first time at our HS Clinic and 50 participants without OCP treatment. The main outcome of interest was the percentage of reduction in total abscess and inflammatory nodule (AN) count at week 12. Thirty-three women received combined OCPs and 17 non-combined OCP. HS patients with OCPs treatment were younger (31.7 vs. 40.9 years, p < 0.001), thinner (28.62 vs. 33.35 kg/m2), and have a higher number of areas affected (2.32 vs. 1.38, p = 0.02) than those without OCPs. After 12-weeks of treatment, it was observed that the percentage of AN reduction was higher in HS women receiving OCP than in patients without OCP (53.9% vs. 38.42%, p = 0.049). It was observed that OCP prescription (β = 3.79, p = 0.034) and concomitant therapy (β = 3.91, p = 0.037) were independently associated with a higher % AN when controlling for disease duration, concomitant therapy, and treatment with/without OCP (R^2 = 0.67). The factors potentially associated with the percentage AN reduction at week 12 in HS women treated with OCPs were disease duration (β = −1.327, p = 0.052), concomitant therapy (β = 11.04, p = 0.079), and HS worsening with the menstrual cycle (β = 10.55, p = 0.087). In conclusion, OCPs might be effective for improving AN count in women with HS. Women whose HS worsens in relation to the menstrual cycle and have a shorter disease may benefit more from the therapeutic effect of OCPs.

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Study the Relationship Between Estrogen Hormone and Calcium in Normal Females Before and After Menopause in Baghdad / Iraq

Al-Kitab Journal for Pure Sciences ◽

10.32441/kjps.v2i1.152 ◽

2018 ◽

Vol 2 (1) ◽

Author(s):

Sameerah Mustafa ◽

Asal Tawfeeq ◽

Hadeel Hasan

Keyword(s):

Oral Contraceptive ◽

Healthy Controls ◽

Serum Samples ◽

Oral Contraceptive Pills ◽

Contraceptive Pills ◽

Menopausal Women ◽

Before And After ◽

Group A ◽

Group B ◽

Age Range

This study involved the collection of (90) samples of women serum which included (30) serum samples collected from women before menopause (reproductive women) in the age range of (22-43) years and were considered as (group A- control). While, (group B) included (30) serum samples collected from women using oral contraceptive pills between the ages of (22-43) years old. Whereas, another (30) serum samples were collected from women after menopause between the ages of (43-54) years and were considered as (group C). All of the collected serum samples were subjected to a number of serological and chemical tests for the measurement of (E2, HDL, LDL and Ca). Then, the obtained data were statistical analyzed and results showed a significant decrease (p˂ 0.05) in (E2 ,Ca and HDL) levels in menopausal women compared to that of the normal healthy controls. While, there were non-significant decrease (p> 0.05) in (E2, Ca and HDL) levels in women taking oral contraceptive when compared to the normal healthy controls. On the other hand, a significant increase (p˂ 0.05) was recorded in LDL level in menopausal women compared to that of the normal healthy controls whereas, no-significant increase (p˃ 0.05) in the LDL level in women taking oral contraceptives when compared to the control women.

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Faculty Opinions recommendation of Comparative study of the therapeutic effects of oral contraceptive pills containing desogestrel, cyproterone acetate, and drospirenone in patients with polycystic ovary syndrome.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717978515.793471100 ◽

2013 ◽

Author(s):

Richard Anderson ◽

Raymond Li

Keyword(s):

Oral Contraceptive ◽

Polycystic Ovary Syndrome ◽

Comparative Study ◽

Cyproterone Acetate ◽

Polycystic Ovary ◽

Therapeutic Effects ◽

Ovary Syndrome ◽

Oral Contraceptive Pills ◽

Contraceptive Pills

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Effect of short-term use of oral contraceptive pills on intraocular pressure

Pakistan Journal of Ophthalmology ◽

10.36351/pjo.v35i3.871 ◽

2020 ◽

Vol 35 (3) ◽

Author(s):

Tayyaba Gul Malik ◽

Hina Nadeem ◽

Eiman Ayesha ◽

Rabail Alam

Keyword(s):

Oral Contraceptive ◽

Childbearing Age ◽

Short Term ◽

Oral Contraceptive Pills ◽

Contraceptive Pills ◽

Time Period ◽

Significant Difference ◽

Group A ◽

Group B ◽

Short Time

Objective: To study the effect of short-term use of oral contraceptive pills on intra-ocular pressures of women of childbearing age. Methods: It was a comparative observational study, conducted at Arif memorial teaching hospital and Allied hospital Faisalabad for a period of six months. Hundred female subjects were divided into two groups of 50 each. Group A, included females, who had been taking oral contraceptive pills (OCP) for more than 6 months and less than 36 months. Group B, included 50 age-matched controls, who had never used OCP. Ophthalmic and systemic history was taken. Careful Slit lamp examination was performed and intraocular pressures (IOP) were measured using Goldman Applanation tonometer. Fundus examination was done to rule out any posterior segment disease. After collection of data, we analyzed and compared the intra ocular pressures between the two groups by using ANOVA in SPSS version 21. Results: Average duration of using OCP was 14.9 months. There was no significant difference of Cup to Disc ratios between the two groups (p= 0.109). However, significant difference was noted between the IOP of OCP group and controls. (p=0.000). Conclusion: OCP significantly increase IOP even when used for short time period.

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Antiticiombin III Deficiency In A Large Family with 41 Affected Members

10.1055/s-0038-1653102 ◽

1981 ◽

Author(s):

J Stibbe ◽

S Adhin ◽

G L Ong ◽

R S Panday ◽

S H Peters ◽

...

Keyword(s):

Autosomal Dominant ◽

Large Family ◽

Clinical Information ◽

Impedance Plethysmography ◽

Age Group ◽

Oral Contraceptive Pills ◽

Contraceptive Pills ◽

At Iii ◽

L 51 ◽

First Time

Hereditary Antithrombin III (AT III) deficiency was found in a large Hindustani family, living partly in the Netherlands, partly in Suriname. Of 201 members investigated 35 were found to affected: AT III activity (chromogenic substrate) and AT III antigen (immuno-electrophoresis according to Laurell) were about 45 %. Analysis of this fanily clearly demonstrated the autosomal dominant inheritance of the condition. Six non-investigated members (1 living, 5 non-living) were diagnosed as being affected on the basis of affected offspring.Seventeen affected members had no signs of thrombo-embolic(TE) processes (age group 0-10 years old, n=2; 11-20, n=5; 21-30, n=4; 31-40, n=4; 41-50, n=2). Thirteen showed clinical or proven signs of TE processes (first time in age group 0-10 years old, n=0; 11-20, n=l; 21-30, n=G; 31-40, n=4; 41-50,n=l; 51-60, n=0; 61-70, n=l). No clinical information is yet available on the remaining affected members. Deep venous thrombosis (DVT) occurred in 9 patients (age group 21-30, n=5; 31-40, n=3; 61-70, n=l). Triggering factors were none 4, surgery 1, oral contraceptives and preg- nancy4. Pulmonary embolism occurred in 6 patients (2 clinical, 4 proven) and was fatal in 4; ages were 19, 21, 26, 37, 48 and 68 years old. Pregnancy was uncomplicated in 3 women (total of 4 pregnancies), one of these women was treated prophylactically with anticoagulants during pregnancy (1 pregnancy). Two women (9 pregnancies) had a thrombotic episode (1st and 3rd pregnancy respectively) and 1 woman died suddenly 7 days after her 7th childbirth. DVT occurred in 2 of 4 women who used oral contraceptive pills.In some symptomless patients (age 22, 26, 32, 33, 40 years old) impedance plethysmography (n=5), 125I-fibrinogen leg scanning (n=3), 125I-fibrinogen T½(n=3) and 51C-platelet survival (n=l) were normal

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Post-operative analgesia following minor surgical excision of cutaneous lesions: How much is necessary?

International Journal of Surgery ◽

10.1016/j.ijsu.2011.07.313 ◽

2011 ◽

Vol 9 (7) ◽

pp. 559

Author(s):

Saikat Ray ◽

Krishna Rao

Keyword(s):

Surgical Excision ◽

Cutaneous Lesions

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Missed oral contraceptive pills: Correction to Handbook of Contraceptive Practice, 1990 edition.

Drug and Therapeutics Bulletin ◽

10.1136/dtb.29.7.28 ◽

1991 ◽

Vol 29 (7) ◽

pp. 28-28

Keyword(s):

Oral Contraceptive ◽

Health Trends ◽

Oral Contraceptive Pills ◽

Contraceptive Pills ◽

Contraceptive Practice

We note an important correction to which the CMO, Health Trends and Prescribers Journal have already drawn attention. The first sentence of section 2.3.14 (p 37) should read “If any pill is omitted from the 21 days of active pills, additional contraception (barriers and spermicides) should be used for the 7 days after the pill(s) has been missed”.

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Knowledge, attitude and practice of contraceptive use among female students of Dilla secondary and preparatory school, Dilla town, South Ethiopia, 2014

Healthcare in Low-resource Settings ◽

10.4081/hls.2016.5680 ◽

2016 ◽

Vol 4 (1) ◽

Author(s):

Samuel Kusheta Katama ◽

Desalegn Tsegaw Hibstu

Keyword(s):

Oral Contraceptive ◽

Contraceptive Use ◽

Female Students ◽

Preparatory School ◽

Oral Contraceptive Pills ◽

South Ethiopia ◽

Attitude And Practice ◽

Contraceptive Pills ◽

Knowledge Attitude And Practice ◽

Injectable Form

Family planning is known not only as a fundamental intervention for improving the health of women but also as a human right. The aim of this study was to assess the current knowledge, attitude and practice of contraceptive use among female students in Dilla secondary and preparatory school, Dilla, South Ethiopia, 2014. A cross sectional study was conducted among 288 female students in Dilla secondary and preparatory school, south Ethiopia, June 19- 29/2014. A simple random sampling technique was used to select the study subjects. The data was collected using a self-administered structured questionnaire. The data was analyzed by SPSS 20. Chi-square test was used to identify associated factors. A total of 263 female students were involved in this study, of which 249 (94.7%) had good knowledge about contraception. The three most frequently identified methods were injectable form (83.9%), oral contraceptive pills (72.7%) and condom (48.6%). A total of 15.7% respondents ever used contraceptive. Among the users, 56.4% used oral contraceptive pills, and 23.1 and 10.2% used injectable form and condom, respectively. In spite of the fact that most respondents had good knowledge of contraception, their attitude and practice was low. Emphasis needs to be given on disseminating health information concerning the attitude and practice of contraceptive method.

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