scholarly journals Complete Blood Count before and after Total Hip or Knee Arthroplasty

2015 ◽  
Vol 23 (2) ◽  
pp. 209-212 ◽  
Author(s):  
Devin M Jagow ◽  
Shahan V Yacoubian ◽  
Stephan V Yacoubian
Keyword(s):  
Knee Arthroplasty ◽  
Blood Count ◽  
Complete Blood Count ◽  
Total Hip ◽  
Before And After

scholarly journals Path of least resistance: how computerised provider order entry can lead to (and reduce) wasteful practices

2018 ◽  
Vol 7 (2) ◽  
pp. e000345 ◽  
Author(s):  
Joseph Choi ◽  
Cori Rebecca Atlin
Keyword(s):  
Blood Count ◽  
Complete Blood Count ◽  
Clinical Care ◽  
Work Flow ◽  
Quality Improvement Initiative ◽  
Order Entry ◽  
Clinical Value ◽  
Careful Planning ◽  
Order Sets ◽  
Before And After

BackgroundComputerised provider order entry (CPOE) is rapidly becoming the mainstay in clinical care and has the potential to improve provider efficiency and accuracy. However, this hinges on careful planning and implementation. Poorly planned CPOE order sets can lead to undetected errors and waste. In our emergency department (ED), lactate dehydrogenase (LDH) was bundled into various blood work panels but had little clinical value.ObjectivesThis quality improvement initiative aimed to reduce unnecessary LDH testing in the ED.MethodsA group of ED physicians reviewed CPOE blood work panels and uncoupled LDH in conditions where it was deemed not to provide any clinically useful information. We measured the daily number of LDH tests performed before and after its removal. We tracked the frequency of other serum tests as controls. We also analysed the number of add-on LDH (ie, to add LDH to samples already sent to the lab) as a balancing measure, since this can disrupt work flow and delay care.ResultsThrough this intervention, we reduced the number of LDH tests performed by 69%, from an average of 75.1 tests per day to 23.2 (P<0.0005). The baseline controls did not differ after the intervention (eg, a complete blood count was performed 197.7 and 196.1 times per day preintervention and postintervention, respectively (P=0.7663)). There was less than one add-on LDH per day on average.ConclusionsCPOE care templates can be powerful in shaping behaviours and reducing variability. However, close oversight of these panels is necessary to prevent errors and waste.

scholarly journals Response to Letter to the Editor on “When Should Complete Blood Count Tests Be Performed in Primary Total Hip Arthroplasty Patients?”

2019 ◽  
Vol 34 (5) ◽  
pp. 1040-1041
Author(s):  
Beau J. Kildow ◽  
Elizabeth P. Howell ◽  
Vasili Karas ◽  
William T. Baumgartner ◽  
Daniel J. Cunningham ◽  
...  
Keyword(s):  
Total Hip Arthroplasty ◽  
Hip Arthroplasty ◽  
Blood Count ◽  
Complete Blood Count ◽  
Total Hip ◽  
Letter To The Editor ◽  
Primary Total Hip Arthroplasty

Presenteeism and Absenteeism Before and After Total Hip and Knee Arthroplasty

2020 ◽  
Author(s):  
Mark A. Fontana ◽  
Wasif Islam ◽  
Michelle A. Richardson ◽  
Cathlyn K. Medina ◽  
Alexander S. McLawhorn ◽  
...  
Keyword(s):  
Knee Arthroplasty ◽  
Total Hip ◽  
Before And After ◽  
Hip And Knee Arthroplasty

scholarly journals The Efficiency of Rectal Fluid Therapy in Moderately Dehydrated Horses

2018 ◽  
Vol 75 (1) ◽  
pp. 73
Author(s):  
Patricia AȘTELEAN ◽  
Eva DIUGAN ◽  
Cristian MOLNAR ◽  
Orsolya SÁRPATAKI ◽  
Răzvan CODEA ◽  
...  
Keyword(s):  
Fluid Therapy ◽  
Blood Count ◽  
Animal Species ◽  
Complete Blood Count ◽  
Rectal Administration ◽  
Response To Therapy ◽  
Blood Samples ◽  
Before And After ◽  
Life Threatening ◽  
Laboratory Investigations

Dehydration and hydro-electrolytic imbalances are relatively common and life threatening conditions in many animal species including horses. In the present study, we highlighted the efficacy of rectal rehydration in horses, nowadays less commonly used. The study was performed on eight non-pregnant mares (Romanian semigreus and Lipiţan breeds), from Beclean horse stud farm, affected by mild dehydration. The method consists in rectal administration in the form of a high enema of a balanced polyionic solution by using an esophageal tube; the solution contains water, sodium chloride and potassium chloride. Blood samples were collected on EDTA and procoagulant vacutainers, before and after fluid therapy. Laboratory investigations include complete blood count and electrolytes measurement, total protein, albumin, and creatinine. Expectedly, dehydrated animals shown borderline elevated hematocrit associated with mild relative hyperproteinemia and hypernatremia, and elevated uremia levels. In all cases, the parameters were restored in response to therapy, and no side effects were recorded.

scholarly journals Investigating the genetic architecture of disease resilience in pigs by genome-wide association studies of complete blood count traits collected from a natural disease challenge model

BMC Genomics ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Xuechun Bai ◽  
Tianfu Yang ◽  
Austin M. Putz ◽  
Zhiquan Wang ◽  
Changxi Li ◽  
...  
Keyword(s):  
Blood Cell ◽  
Genetic Architecture ◽  
Blood Count ◽  
Complete Blood Count ◽  
Association Studies ◽  
Genome Wide Association ◽  
Genome Wide Association Studies ◽  
Genome Wide ◽  
Before And After ◽  
Genomic Regions

Abstract Background Genetic improvement for disease resilience is anticipated to be a practical method to improve efficiency and profitability of the pig industry, as resilient pigs maintain a relatively undepressed level of performance in the face of infection. However, multiple biological functions are known to be involved in disease resilience and this complexity means that the genetic architecture of disease resilience remains largely unknown. Here, we conducted genome-wide association studies (GWAS) of 465,910 autosomal SNPs for complete blood count (CBC) traits that are important in an animal’s disease response. The aim was to identify the genetic control of disease resilience. Results Univariate and multivariate single-step GWAS were performed on 15 CBC traits measured from the blood samples of 2743 crossbred (Landrace × Yorkshire) barrows drawn at 2-weeks before, and at 2 and 6-weeks after exposure to a polymicrobial infectious challenge. Overall, at a genome-wise false discovery rate of 0.05, five genomic regions located on Sus scrofa chromosome (SSC) 2, SSC4, SSC9, SSC10, and SSC12, were significantly associated with white blood cell traits in response to the polymicrobial challenge, and nine genomic regions on multiple chromosomes (SSC1, SSC4, SSC5, SSC6, SSC8, SSC9, SSC11, SSC12, SSC17) were significantly associated with red blood cell and platelet traits collected before and after exposure to the challenge. By functional enrichment analyses using Ingenuity Pathway Analysis (IPA) and literature review of previous CBC studies, candidate genes located nearby significant single-nucleotide polymorphisms were found to be involved in immune response, hematopoiesis, red blood cell morphology, and platelet aggregation. Conclusions This study helps to improve our understanding of the genetic basis of CBC traits collected before and after exposure to a polymicrobial infectious challenge and provides a step forward to improve disease resilience.

scholarly journals Investigating the genetic architecture of disease resilience in pigs by genome-wide association studies of complete blood count traits collected from a natural disease challenge model

2020 ◽  
Author(s):  
Xuechun Bai ◽  
Tianfu Yang ◽  
Austin Putz ◽  
Zhiquan Wang ◽  
Changxi Li ◽  
...  
Keyword(s):  
Blood Cell ◽  
Genetic Architecture ◽  
Blood Count ◽  
Complete Blood Count ◽  
Association Studies ◽  
Genome Wide Association ◽  
Genome Wide Association Studies ◽  
Genome Wide ◽  
Before And After ◽  
Genomic Regions

Abstract BackgroundGenetic improvement for disease resilience is anticipated to be a practical method to improve efficiency and profitability of the pig industry, as resilient pigs maintain a relatively undepressed level of performance in the face of infection. However, multiple biological functions are known to be involved in disease resilience and this complexity means that the genetic architecture of disease resilience remains largely unknown. Here, we conducted genome-wide association studies (GWAS) of 465,910 autosomal SNPs for complete blood count (CBC) traits that are important in an animal’s disease response. The aim was to identify the genetic control of disease resilience.ResultsUnivariate and multivariate single-step GWAS were performed on fifteen CBC traits measured from the blood samples of 2743 crossbred (Landrace × Yorkshire) barrows drawn at 2-weeks before, and at 2 and 6-weeks after exposure to a polymicrobial infectious challenge. Overall, at a genome-wise false discovery rate of 0.05, five genomic regions located on Sus scrofa chromosome (SSC) 2, SSC4, SSC9, SSC10, and SSC12, were significantly associated with white blood cell traits in response to the polymicrobial challenge, and nine genomic regions on multiple chromosomes (SSC1, SSC4, SSC5, SSC6, SSC8, SSC9, SSC11, SSC12, SSC17) were significantly associated with red blood cell and platelet traits collected before and after exposure to the challenge. By functional enrichment analyses using Ingenuity Pathway Analysis (IPA) and literature review of previous CBC studies, candidate genes located nearby significant single-nucleotide polymorphisms were found to be involved in immune response, hematopoiesis, red blood cell morphology, and platelet aggregation.ConclusionsThis study helps to improve our understanding of the genetic basis of CBC traits collected before and after exposure to a polymicrobial infectious challenge and provides a step forward to improve disease resilience.

Chronic Prescription Opioid Use Before and After Total Hip and Knee Arthroplasty in Patients Younger Than 65 Years

2019 ◽  
Vol 34 (10) ◽  
pp. 2319-2323 ◽  
Author(s):  
Eric Y. Chen ◽  
Rachel Lasky ◽  
William A. Dotterweich ◽  
Ruijia Niu ◽  
David J. Tybor ◽  
...  
Keyword(s):  
Knee Arthroplasty ◽  
Prescription Opioid ◽  
Opioid Use ◽  
Total Hip ◽  
Before And After ◽  
Hip And Knee Arthroplasty ◽  
Prescription Opioid Use
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