scholarly journals Conservative Treatment for Plantar Fasciitis

2018 ◽  
Vol 3 (2) ◽  
pp. 2473011418S0000
Author(s):  
Carlos Jasmin Alfredo Lobo
Keyword(s):  
Plantar Fasciitis ◽  
Diclofenac Sodium ◽  
Randomized Study ◽  
Local Infiltration ◽  
Group Iii ◽  
Muscle Stretching ◽  
Group I ◽  
Evaluation Group ◽  
Group Ii ◽  
Night Splints

Category: Hindfoot Introduction/Purpose: The objective of this study was to compare the results obtained in the treatment of plantar fasciitis, by: group I, muscle stretching (plantar and gastrocnemius); Group II, use of the dorsiflexion night splints; and group III, permanent elevation use of shoe heel, 2 cm or more, in relation to forefoot. Methods: One hundred and fifty patients participated in the prospective and randomized study. After randomizing the method, the patients received treatment orientation. Prescription: 150 mg diclofenac sodium, single daily dose, for 7 days. Group II, they underwent daily physiotherapy with plantar stretching and electrotherapy, associated to the use of the night splints. The evaluations were at 30 and 60 days. In the first evaluation, eight patients underwent local infiltration of betamethasone dipropionate, betamethasone disodium phosphate: five from Group I and three from Group II. All patients were evaluated on the AOFAS score of the hindfoot. Results: First evaluation: group I, 52% showed little improvement (AOFAS: initial 53.5, 30 days 56.6); Group II, 38% were dissatisfied and uncomfortable with the night splints (AOFAS: initial 55.6, 30 days 63.3). In group III, 22% of the patients reported pain arising in the morning and after periods of sitting (AOFAS: initial 57.7, 30 days 81.6). Second evaluation: Group I, AOFAS 56.9; Group II AOFAS 72.2; group III AOFAS 88.6. Conclusion: heel elevation presented a satisfactory result, superior to the other methods used; difficulty for patient’s adhesion because it eliminates usage of shoes with no heels; AOFAS / scale close to all patients treated.

scholarly journals Study on Efficacy of Nalbuphine Hydrochloride as Pre-Emptive Analgesic – Comparison With Diclofenac Sodium after Open Cholecystectomy

2009 ◽  
Vol 20 (2) ◽  
pp. 39-44
Author(s):  
Md Quamrul Islam ◽  
Hasina Begum ◽  
AKM Akhtaruzzaman ◽  
UH Shahera Khatun
Keyword(s):  
Muscle Relaxation ◽  
Open Cholecystectomy ◽  
Diclofenac Sodium ◽  
Randomized Study ◽  
Afferent Input ◽  
P Value ◽  
Group Iii ◽  
Central Processing ◽  
Group I ◽  
Group Ii

Preemptive analgesia is an antinociceptive treatment that prevents establishment of altered central processing of afferent input from sites of injury. The aim of this study was to evaluate the effects of preemptively used nalbuphine and diclofenac on postoperative pain and opioid consumption. Seventy five patients scheduled for open cholecystectomy were investigated by randomized study. Patients were divided into three groups. In group I, patients received Inj. Nalbuphine Hydrochloride (0.3 mg/kg bw IV) before induction. In group II, patients received Inj. Diclofenac Sodium (1 mg/kg bw IV) before induction and in group III patients received placebo before induction. General Anesthesia was given in all groups with Inj. Thiopental sodium 5mg/kg and Inj. Succninylcholine 1.5mg/kg to facilitate endotracheal intubation. Anesthesia was maintained with halothane 0.5% and nitrous oxide 66% in oxygen. Muscle relaxation was maintained by Inj.Vecuronium 0.1 mg/kg. Intraoperative proper hydration was maintained by lactate ringer's solution.In post operative period patients in all three groups received Inj. Pethidine 10mg IV till the patients got relieved from pain. The minimum interval of giving pethidine was 10 minutes. Through our study we have found that, pethidine consumption in 24 hours in group-I (Nalbuphine group) was 54.00±1.0, in group-II (Diclofenac group) was 74.00±1.0 and in group-III (Placebo group) was 112.0±2.0 and p-value <0.001, which is highly significant (measured in mg). Time of first pethidine demand in group-I was 45.83±10.93, in group-II was 34.20±5.44and in group-III was 16.21±3.62 and p-value<0.001 which is also highly significant (measured in minute). Overall patients satisfaction was high in nalbuphine group. Under the condition of present study, we can conclude that preemptively used nalbuphine hydrochloride decreases post operative pain and opioid demand. Journal of BSA, Vol. 20, No. 2, July 2007 p.39-44

scholarly journals THE EFFECT OF SILODOSIN AND SODIUM DICLOFENAC TO REDUCE PAIN AFTER DJ STENT REMOVAL IN SOETOMO HOSPITAL: DOUBLE-BLINDED RANDOMIZED-CONTROLLED TRIAL

2019 ◽  
Vol 26 (1) ◽  
Author(s):  
Hasroni Fathurrahman ◽  
Doddy M Soebadi ◽  
Lukman Hakim
Keyword(s):  
Controlled Trial ◽  
Diclofenac Sodium ◽  
Pain Scale ◽  
Test Results ◽  
Group Iii ◽  
Stent Removal ◽  
Group I ◽  
Dj Stent ◽  
Group Ii ◽  
Double Blinded

Objective: To analyze, measure, compare, prove, and evaluate effectiveness of silodosin, diclofenac sodium, and the combination of both drugs in pain management after stent removal. Materials & Methods: Thirty-three patients were divided into three groups. Group I was given diclofenac Sodium 50 mg, group II was given silodosin 8 mg and group III was given the combination of diclofenac sodium 50 mg and silodosin 8 mg. The Wong Baker Pain Scale (WBPS) was assessed serially: two hours before the DJ stent removal, during DJ stent removal, and after the DJ stent removal (2 hours and 24 hours after). The data was analyzed by ANOVA and Kruskal-Wallis test. Results: In this study, 33 patients who underwent DJ stent removal were obtained. Wong Baker was presented in median (min-max) form. The WBPS study in each group did not differ statistically significant. Lowest WBPS during DJ stent removal was found in group III. Group III was better and statistically significant in reducing pain compared to group I and group II (p<0.05). WBPS two hours after removal in each group decreased and group III was better and statistically significant in reducing pain compared to group II, whereas group III compared to group I had an equivalent effectiveness. While the WBPS 24 hours after removal had the same value and did not differ significantly. No side effects or adverse events were found in the use of diclofenac sodium, silodosin, and their combinations. Conclusion: Single oral dose of diclofenac sodium combined with silodosin is effective to reduce pain after DJ stent removal.

Listening to Music during Outpatient Cystoscopy Reduces Pain and Anxiety and Increases Satisfaction: Results from a Prospective Randomized Study

2021 ◽  
pp. 1-7
Author(s):  
Jan-Niclas Mumm ◽  
Lennert Eismann ◽  
Severin Rodler ◽  
Theresa Vilsmaier ◽  
Alaleh Zati Zehni ◽  
...  
Keyword(s):  
Statistical Analysis ◽  
Pain Score ◽  
Classical Music ◽  
Randomized Study ◽  
Rank Correlation ◽  
Control Group ◽  
Group Iii ◽  
Group I ◽  
Group Ii ◽  
Satisfaction Rates

<b><i>Background:</i></b> This study investigates the effect of classical music, music of patients’ own choice, or no music on pain reduction during elective cystoscopy. <b><i>Objectives:</i></b> The aim of the study was to describe the effect of listening to classical music, music of patients’ own choice, or no music on patient’s pain and satisfaction rates when carrying out an elective cystoscopy and the effect on the assessment capability of the performing urologist. <b><i>Design, Setting, and Participants:</i></b> This randomized trial included 127 patients undergoing elective cystoscopy at the Urological Department of the University Clinic of Munich between June 2019 and March 2020. <b><i>Outcome Measurements and Statistical Analysis:</i></b> Patients were assigned randomly to 3 groups: group I: listening to standardized classical music (<i>n</i> = 35), group II: listening to music according to the patients’ choice (<i>n</i> = 34), and control group III: no music (<i>n</i> = 44). Prior to cystoscopy, anxiety levels were assessed by the Beck Anxiety Inventory (BAI). The Visual Analog Scale (VAS, range 1–100) was used for a self-assessment of pain, discomfort, and satisfaction. Statistical analysis was done with Spearman’s rank correlation and <i>t</i>-tests. <b><i>Results and Limitations:</i></b> The median age was 63 (range 27–91) years. The duration of cystoscopy was 5.7 (1–30) min. Patients had undergone a median of 2.3 cystoscopies in the past. Between giving informed consent and cystoscopy, patients had to wait for a median of 64 (0–260) min. The median VAS pain score was significantly lower in group I at 1.7 and group II at 2.3 versus 5.2 in the control group III (<i>p</i> &#x3c; 0.001). The control group III had significantly worse pain and patient satisfaction rates compared with groups I and II. Group I had a significant lower VAS pain score than groups II and III (<i>p</i> &#x3c; 0.001). Classical music also increased the assessment capability of the preforming urologist. <b><i>Conclusions:</i></b> Listening to music during elective cystoscopy significantly reduces pain and distress and leads to higher patient and surgeon satisfaction. We recommend listening to classical music or music chosen by the patients during outpatient flexible/rigid cystoscopy in daily clinical routine. <b><i>Patient Summary:</i></b> In this study, we found that patients who listened to classical music or music of their own choice while undergoing a cystoscopy showed significant reduction of pain and distress.

scholarly journals Comparison of Propofol, Propofol-Remifentanil, and Propofol-Fentanyl Administrations with Each Other Used for the Sedation of Patients to Undergo ERCP

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Candan Haytural ◽  
Bahar Aydınlı ◽  
Berna Demir ◽  
Elif Bozkurt ◽  
Erkan Parlak ◽  
...  
Keyword(s):  
Total Dose ◽  
Rating Scale ◽  
Numerical Rating Scale ◽  
Randomized Study ◽  
Anesthetic Agent ◽  
Group Iii ◽  
Group I ◽  
Numerical Rating ◽  
Group Ii ◽  
High Doses

Introduction. Using single anesthetic agent in endoscopic retrograde cholangiopancreatography (ERCP) may lead to inadequate analgesia and sedation. To achieve the adequate analgesia and sedation the single anesthetic agent doses must be increased which causes undesirable side effects. For avoiding high doses of single anesthetic agent nowadays combination with sedative agents is mostly a choice for analgesia and sedation for ERCP.Aim. The aim of this study is to investigate the effects of propofol alone, propofol + remifentanil, and propofol + fentanyl combinations on the total dose of propofol to be administered during ERCP and on the pain scores after the process.Materials and Method. This randomized study was performed with 90 patients (ASA I-II-III) ranging between 18 and 70 years of age who underwent sedation/analgesia for elective ERCP. The patients were administered only propofol (1.5 mg/kg) in Group Ι, remifentanil (0.05 μg/kg) + propofol (1.5 mg/kg) combination in Group II, and fentanyl (1 μg/kg) + propofol (1.5 mg/kg) combination in Group III. All the patients’ sedation levels were assessed with the Ramsey Sedation Scale (RSS). Their recovery was assessed with the Aldrete and Numerical Rating Scale Score (NRS) at 10 min intervals.Results. The total doses of propofol administered to the patients in the three groups in this study were as follows: 375 mg in Group I, 150 mg in Group II, and 245 mg in Group III.Conclusion. It was observed that, in the patients undergoing ERCP, administration of propofol in combination with an opioid provided effective and reliable sedation, reduced the total dose of propofol, increased the practitioner satisfaction, decreased the pain level, and provided hemodynamic stability compared to the administration of propofol alone.

scholarly journals Silodosin versus Tamsulosin as Medical Expulsive Therapy for Children with Lower-Third Ureteric Stones: Prospective Randomized Placebo-Controlled Study

2021 ◽  
pp. 1-6
Author(s):  
Mohamed G. Soliman ◽  
Osama El-Gamal ◽  
Samir El-Gamal ◽  
Ali Abdel Raheem ◽  
Ahmed Abou-Ramadan ◽  
...  
Keyword(s):  
Randomized Study ◽  
Study Groups ◽  
Controlled Study ◽  
Expulsion Rate ◽  
Medical Expulsive Therapy ◽  
Group Iii ◽  
Group I ◽  
Younger Age ◽  
Significant Difference ◽  
Group Ii

<b><i>Aim:</i></b> To compare the efficacy and safety of silodosin versus tamsulosin as medical expulsive therapy for stones of lower-third ureter in children. <b><i>Patients and Methods:</i></b> This prospective single-blind placebo-controlled randomized study included 167 pediatric patients who presented with distal ureteric stone (DUS) less than 1 cm. Patients were randomized into 3 groups; group I received silodosin 4 mg once daily, and group II received tamsulosin 0.4 mg while those in group III had placebo. The side effects of the used drugs, both rate and time of stone expulsion, and number of pain episodes were compared among the study groups for a maximum of 4 weeks. <b><i>Results:</i></b> Follow-up data of our patients after treatment revealed that the stone expulsion rate was significantly higher and the time to stone expulsion was significantly shorter in group I (89.3%, 12.4 ± 2.3 days) and group II (74.5%, 16.2 ± 4.2 days) compared to group III (51.8%, 21.2 ± 5.6). However, a statistically significant difference between silodosin and tamsulosin groups in favor of the former one was reported regarding the 2 studied items. Meanwhile, pain episodes requiring analgesia were statistically fewer in group I and II in contrast to placebo group. Adverse events were comparable among all groups. <b><i>Conclusion:</i></b> Silodosin provides significantly better stone expulsion rate and shorter expulsion time than tamsulosin for treatment of DUS. Both medications showed good safety profiles in children. However, further studies are required on a larger scale to confirm our results. Assessment of drug safety on younger age-group is still needed.

scholarly journals Studies in A-scan echoencephalography: evaluation of a proposed two phase shift

1969 ◽  
Vol 27 (3) ◽  
pp. 199-206
Author(s):  
Helio Lemmi ◽  
Amin A. Faris ◽  
Joseph Belluomini
Keyword(s):  
Phase Shift ◽  
Midline Shift ◽  
Two Phase ◽  
Group Iii ◽  
Group I ◽  
Evaluation Group ◽  
Group Ii

A series of 440 patients studied by echoencephalography is reported. Rather than dividing the patients in the classic two groups of less than 3 mm and more than 3 mm deviation of the midline, the patients in this study were divided into three groups, correlating the degree of midline shift to the presence of intracranial pathology. Group I, showing 0 to 2.5 mm shift proves to be normal with a "miss" rate of only 10%. Group II, showing 2.5 to 3.5 mm shift is regarded as a borderline group with an incidence of significant intracranial pathology of 46%, clearly indicating the need for further evaluation. Group III, demonstrating greater than 3.5 mm shift from the midline, is designated with confidence as abnormal, with a yield of significant intracranial pathology of 100% in this study.

scholarly journals [NO TITLE AVAILABLE]

1998 ◽  
Vol 13 (1) ◽  
pp. 37-43 ◽  
Author(s):  
José Guilherme Minossi ◽  
Celso Vieira de Souza Leite ◽  
Luiz Eduardo Naresse ◽  
Maria Aparecida M. Rodrigues ◽  
Paulo Roberto Curi ◽  
...  
Keyword(s):  
Tensile Strength ◽  
Wistar Rats ◽  
Diclofenac Sodium ◽  
Group Iv ◽  
Clinical Parameters ◽  
Control Groups ◽  
Group Iii ◽  
Group I ◽  
Group Ii ◽  
Tensile Strenght

The effect of the diclofenac sodium (DS) on the healing of anastomosis carried- out in the ileum of rats was studied. Five- hundred and nineteen Wistar rats were randomly assigned to the 4 experimental groups: Group I included 52 rats treated with 3 mg/kg/day of saline, administered intramusculary during 4 days, group II included 110 rats submitted to ileal anastomosis and treated with saline as described previously, group III included 52 rats treated with DS in a dose of 3 mg/kg/day, administered IM during 4 days, and group IV included 295 rats submitted to ileal anastomosis and treated with DS as prior described. In all rats from the 4 experimental groups clinical parameters and measurements of tensile strength, tissue collagen and histological analyses were documented at 4, 7, 14, and 21 postoperative days. There are no clinical alterations in group I rats all over the study. Diarrhoea was observed in 8 rats (15,4%) from group III. In this group both tensile strenght and tissue collagen were descrease when compared with group I rats. Mortality in DS treated rats submitted to ileal anastomosis was higher than those of control groups. In group IV we also observed reard in the healing, with intense PMN inflamatory response, decrease of macrophages and of tissue collagen, and mucosae regeneration. We concluded that DS is deleterious on the healing of anastomosis performed in the ileum of rats

scholarly journals Midazolam and Thiopentone as Co-Induction

2009 ◽  
pp. 23-27
Author(s):  
Md Habibur Rahman ◽  
Mahbub Hassan ◽  
Md Monirul Islam
Keyword(s):  
Blood Pressure ◽  
Induction Time ◽  
Randomized Study ◽  
Induction Agent ◽  
Double Blind ◽  
Group Iii ◽  
Midazolam Group ◽  
Thiopentone Sodium ◽  
Group I ◽  
Group Ii

This study was undertaken to compare the induction characteristics of conventional thiopentone sodium, midazolam, and a combination of midazolam and thiopentone sodium as co-induction agent. Total one hundred and fifty patients of ASA grade I and II were divided into three groups in a double blind randomized study. Group-I received midazolam 0.25 mgkg-1 intravenously, group-II received thiopentone sodium 5 mgkg-1 intravenously and Group-III received midazolam 0.1 mg/kg-1 IV followed by thiopentone sodium 2.5 mg/kg-1 IV. Induction time was significantly prolonged with midazolam (group-II) compared to thiopentone sodium. The fall in systolic blood pressure (SBP) and diastolic blood pressure (DBP) was clinically insignificant in midazolam group. Induction with midazolam was not smooth and was associated with unwanted movement of limbs. Incidence of apnoea, pain, thrombophlebites were significantly less with midazolam. Co-induction with midazolam and thiopentone significantly reduced the induction time, unwanted movements of limbs, apnoea during induction and cardiovascular stability was also more in co-induction group than thiopenfone sodium group. Incidence and duration of drowsiness was also significantly lesser in coinduction group. These advantages signifies that combination of midazolan and thiopentone is better choice for induction of anaesthesia than the other conventional induction agent like individual midazolam or thiopentone.DOI: http://dx.doi.org/10.3329/jbsa.v17i1.4047 Journal of BSA, Vol. 17, No. 1 & 2, 2004 p.23-27

scholarly journals The Comparison of the Effects of Ellagic Acid and Diclofenac Sodium on Intra-Abdominal Adhesion: An In Vivo Study in the Rat Model

2014 ◽  
Vol 99 (5) ◽  
pp. 543-550 ◽  
Author(s):  
Tulay Diken Allahverdi ◽  
Ertuğrul Allahverdi ◽  
Sadık Yayla ◽  
Turgay Deprem ◽  
Oğuz Merhan ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Ellagic Acid ◽  
Diclofenac Sodium ◽  
Peritoneal Adhesion ◽  
Peritoneal Adhesions ◽  
Group Iii ◽  
Group I ◽  
Anti Inflammatory ◽  
Group Ii

Abstract Peritoneal adhesions are seen frequently after abdominal surgery and can cause serious complications. We aimed to evaluate the effects of the oral use of diclofenac sodium and ellagic acid on formation of postoperative adhesions in rats Studies have shown that agents with anti-inflammatory properties and antioxidant substances can prevent adhesion by decreasing oxidative stress. We compared and evaluated the effects of ellagic acid that has strong antioxidant and anti-inflammatory properties and the nonsteroidal anti-inflammatory diclofenac sodium on peritoneal adhesion development in our experimental study. Laparotomy was performed with a midline incision under general anesthesia and an adhesion model was created on the antimesenteric side of the cecum in Groups I, II, and III. Group I received 85 mg/kg ellagic acid and Group II, 50 mg/kg diclofenac sodium through the nasogastric catheter while Group III received no medication. Only laparotomy was performed in Group IV. The rats were sacrificed at the end of the 14th day. Following macroscopic scoring, tissue samples were removed and subjected to biochemical and histopathologic evaluation. The degree of adhesion and the malondialdehyde level were decreased (P &lt; 0.05), and glutathione level increased (P &lt; 0.05) in Group I compared to Group II and Group III. The effects of ellagic acid on the prevention of peritoneal adhesion were found to be stronger than diclofenac sodium. This can be explained by the fact that ellagic acid is a strong antioxidant and decreases oxidative stress with anti-inflammatory and anti-angiogenic effects.

Ultrastructural Lesions Produced by Alcohol and Sucrose in the Heart and Liver of C57BL Mice

1970 ◽  
Vol 28 ◽  
pp. 208-209
Author(s):  
K.K. SEKHRI ◽  
C.S. ALEXANDER ◽  
H.T. NAGASAWA
Keyword(s):  
Osmium Tetroxide ◽  
Male Mice ◽  
Alcohol Group ◽  
Group Iii ◽  
Group I ◽  
C57bl Mice ◽  
Group Ii

C57BL male mice (Jackson Lab., Bar Harbor, Maine) weighing about 18 gms were randomly divided into three groups: group I was fed sweetened liquid alcohol diet (modified Schenkl) in which 36% of the calories were derived from alcohol; group II was maintained on a similar diet but alcohol was isocalorically substituted by sucrose; group III was fed regular mouse chow ad lib for five months. Liver and heart tissues were fixed in 2.5% cacodylate buffered glutaraldehyde, post-fixed in 2% osmium tetroxide and embedded in Epon-araldite.

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