scholarly journals Vestibular Characteristics of Patients with Chronic Rhinosinusitis

OTO Open ◽  
2018 ◽  
Vol 2 (4) ◽  
pp. 2473974X1880499
Author(s):  
Sabrina Brody-Camp ◽  
John A. Risey ◽  
Edward D. McCoul
Keyword(s):  
Chronic Rhinosinusitis ◽  
Preliminary Report ◽  
Vestibular Function ◽  
Subjective Symptom ◽  
Common Disease ◽  
Disease Entity ◽  
Limited Data ◽  
Wide Range ◽  
The Relationship ◽  
Prospective Database

Chronic rhinosinusitis (CRS) is a common disease entity with symptoms that may extend beyond the sinonasal tract. Limited data exist regarding the relationship between CRS and the vestibular system, and no previous study has investigated the association between objective vestibular findings on videonystagmography (VNG) and the diagnosis of CRS. We analyzed a prospective database of 3078 patients who underwent VNG at our institution over an 8-year period, which included 70 subjects who had a diagnosis of CRS assigned by an otolaryngologist. Overall, the VNG findings for patients with CRS were similar to those of the general population, with 50% exhibiting normal vestibular function. Peripheral lesions were the most common abnormal VNG finding, with a wide range of subjective symptom descriptions. This preliminary report of the prevalence of objective vestibular findings in patients with CRS may form the basis for future study.

scholarly journals Intraoperative Applications of Topical Corticosteroid Therapy for Chronic Rhinosinusitis

2020 ◽  
pp. 014556132097010
Author(s):  
Matthew J. Lelegren ◽  
Randall A. Bloch ◽  
Kent K. Lam
Keyword(s):  
Topical Corticosteroid ◽  
Chronic Rhinosinusitis ◽  
Corticosteroid Therapy ◽  
Calcium Alginate ◽  
Sinus Surgery ◽  
Efficacy And Safety ◽  
Limited Data ◽  
Wide Range ◽  
Comprehensive Search ◽  
Ocular Safety

Objectives: To provide an overview of recent techniques and technologies for the application of topical corticosteroid therapy immediately following endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS). Methods: A comprehensive search in the PubMed and Google Scholar databases was conducted to identify publications between January 2000 and December 2019 detailing clinical trials that have evaluated the efficacy and safety of intraoperative applications of topical corticosteroids for CRS. Results: A total of 21 articles, all of which highlight a variety of corticosteroid-infused products, including Propel corticosteroid-eluting stents, NasoPore, Merocel, SinuBand, calcium alginate, and bioresorbable gel-type products, are included for review. Propel stents are the only devices that have achieved level 1A evidence in terms of efficacy and have data to support their safety. The remaining products have shown mixed results in terms of efficacy and safety. Conclusion: A wide range of techniques and technologies have been introduced to enhance the topical delivery of corticosteroids into the neosinuses after ESS for CRS. Regarding efficacy, there is level 1A evidence to support the use of Propel stents. Most of the remaining strategies show some degree of efficacy. Direct comparisons across the different strategies are limited owing to the varied uses of delivery vectors, corticosteroid choices, and doses of corticosteroids. Propel stents and SinuBand have sufficient data to support systemic and ocular safety, whereas the remaining products have limited data to support their safety.

scholarly journals Biofilms and nasal wound healing in postsurgical patients with chronic rhinosinusitis - A review of literature

2015 ◽  
Vol 5 (20) ◽  
pp. 203-208
Author(s):  
Veronica Trombitas ◽  
Alina Anda Nagy ◽  
Diana Vlad ◽  
Ilea Aranka ◽  
Silviu Albu
Keyword(s):  
Chronic Rhinosinusitis ◽  
Focal Point ◽  
Treatment Strategies ◽  
Signs And Symptoms ◽  
Bacterial Biofilm ◽  
Sinus Surgery ◽  
Common Disease ◽  
Favourable Evolution ◽  
The Relationship ◽  
Sinus Mucosa

AbstractChronic rhinosinusitis (CRS), fairly common disease in the field of otorhinolaryngology, is the focal point of thorough study of the pathophysiology and treatment strategies for a favourable evolution of patients with this problem. Although there have been important advances in the treatment of CRS, signs and symptoms still remain long after functional endoscopic sinus surgery (FESS), indicating the persistence of the biofilm infection on the sinus mucosa. This review aims to highlight the relationship between bacterial biofilm and CRS, and also the available treatment strategies of the latter.

A comparison of the relationship between measured acoustic response and porosity in carbonates across different geologic periods, depositional basins, and with variable mineral composition

2018 ◽  
Vol 6 (2) ◽  
pp. T245-T256
Author(s):  
Beth Vanden Berg ◽  
Christophe Nussbaumer ◽  
Amy Noack ◽  
John Thornton ◽  
Ralf J. Weger ◽  
...  
Keyword(s):  
Carbonate Platform ◽  
Order Estimate ◽  
Michigan Basin ◽  
Limited Data ◽  
Data Set ◽  
Paradox Basin ◽  
Great Bahama Bank ◽  
Wide Range ◽  
Basic Relationship ◽  
The Relationship

Recent work has shown that there is a predictable inverse relationship between laboratory-measured sonic velocity response and porosity in carbonates, which can be reasonably approximated using the empirical Wyllie time-average equation (WTA). The relationship was initially identified in late Cretaceous to Cenozoic age samples collected from the Great Bahama Bank and the Maiella Platform, an exhumed Cretaceous carbonate platform in Italy. We have compared older carbonate samples from different basins and different geologic ages to determine the applicability of this relationship and subsequent correlations to key petrophysical properties to other carbonate basins and other geologic time periods. The data set used for the comparison shows this relationship to be relatively consistent in other depositional basins (Michigan Basin, Paradox Basin) and with samples from older geologic periods (Pennsylvanian, Ordovician, and Mississippian). However, this basic relationship is also observed to vary significantly within a reservoir system and within a depositional basin in samples from different geologic periods (e.g., Silurian- versus Ordovician-age rocks in the Michigan Basin). Although the empirical WTA can generally be applied as a first-order estimate across a wide range of sample ages in carbonates, limited data suggest the relationship between velocity and porosity to be moderately more complex. For instance, in unconventional carbonate reservoirs characterized by predominantly micro- to nanoscale porosity, it is observed that the WTA should be applied as an upper data boundary. In addition, this study has shown that the relationship to the dominant pore type is less direct than in a macropore system in which it can be assumed that the dominant pore type also has the greatest effect on the effective permeability.

The Problem of Identifying and Modeling the Relationship between Monetary Factor and Inflation in the Russian Economy

2008 ◽  
pp. 61-76
Author(s):  
A. Porshakov ◽  
A. Ponomarenko
Keyword(s):  
Money Supply ◽  
Money Demand ◽  
Russian Economy ◽  
Long Run ◽  
Complex Approach ◽  
Wide Range ◽  
Long Time ◽  
The Relationship ◽  
Supply Side Factors

The role of monetary factor in generating inflationary processes in Russia has stimulated various debates in social and scientific circles for a relatively long time. The authors show that identification of the specificity of relationship between money and inflation requires a complex approach based on statistical modeling and involving a wide range of indicators relevant for the price changes in the economy. As a result a model of inflation for Russia implying the decomposition of inflation dynamics into demand-side and supply-side factors is suggested. The main conclusion drawn is that during the recent years the volume of inflationary pressures in the Russian economy has been determined by the deviation of money supply from money demand, rather than by money supply alone. At the same time, monetary factor has a long-run spread over time impact on inflation.

scholarly journals Polymorphic Iterable Sequential Effect Systems

2021 ◽  
Vol 43 (1) ◽  
pp. 1-79
Author(s):  
Colin S. Gordon
Keyword(s):  
Algebraic Structure ◽  
Position Effect ◽  
Type Systems ◽  
Sequential Effect ◽  
Prior Work ◽  
Sequential Effects ◽  
Wide Range ◽  
The Relationship ◽  
Categorical Semantics

Effect systems are lightweight extensions to type systems that can verify a wide range of important properties with modest developer burden. But our general understanding of effect systems is limited primarily to systems where the order of effects is irrelevant. Understanding such systems in terms of a semilattice of effects grounds understanding of the essential issues and provides guidance when designing new effect systems. By contrast, sequential effect systems—where the order of effects is important—lack an established algebraic structure on effects. We present an abstract polymorphic effect system parameterized by an effect quantale—an algebraic structure with well-defined properties that can model the effects of a range of existing sequential effect systems. We define effect quantales, derive useful properties, and show how they cleanly model a variety of known sequential effect systems. We show that for most effect quantales, there is an induced notion of iterating a sequential effect; that for systems we consider the derived iteration agrees with the manually designed iteration operators in prior work; and that this induced notion of iteration is as precise as possible when defined. We also position effect quantales with respect to work on categorical semantics for sequential effect systems, clarifying the distinctions between these systems and our own in the course of giving a thorough survey of these frameworks. Our derived iteration construct should generalize to these semantic structures, addressing limitations of that work. Finally, we consider the relationship between sequential effects and Kleene Algebras, where the latter may be used as instances of the former.

Age-Dependency of Total Tau in the Cerebrospinal Fluid Is Corrected by Amyloid-β 1–40: A Correlational Study in Healthy Adults

2021 ◽  
pp. 1-8
Author(s):  
Paul Theo Zebhauser ◽  
Achim Berthele ◽  
Marie-Sophie Franz ◽  
Oliver Goldhardt ◽  
Janine Diehl-Schmid ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Amyloid Β ◽  
Healthy Adults ◽  
Tau Proteins ◽  
Clinical Settings ◽  
Inclusion Criteria ◽  
Total Tau ◽  
Potential Marker ◽  
Wide Range ◽  
The Relationship

Background: Tau proteins are established biomarkers of neuroaxonal damage in a wide range of neurodegenerative conditions. Although measurement of total-Tau in the cerebrospinal fluid is widely used in research and clinical settings, the relationship between age and total-Tau in the cerebrospinal fluid is yet to be fully understood. While past studies reported a correlation between age and total-Tau in the cerebrospinal fluid of healthy adults, in clinical practice the same cut-off value is used independently of patient’s age. Objective: To further explore the relationship between age and total-Tau and to disentangle neurodegenerative from drainage-dependent effects. Methods: We analyzed cerebrospinal fluid samples of 76 carefully selected cognitively healthy adults and included amyloid-β 1–40 as a potential marker of drainage from the brain’s interstitial system. Results: We found a significant correlation of total-Tau and age, which was no longer present when correcting total-Tau for amyloid-β 1–40 concentrations. These findings were replicated under varied inclusion criteria. Conclusion: Results call into question the association of age and total-Tau in the cerebrospinal fluid. Furthermore, they suggest diagnostic utility of amyloid-β 1–40 as a possible proxy for drainage-mechanisms into the cerebrospinal fluid when interpreting biomarker concentrations for neurodegenerative diseases.

scholarly journals Modelling the elastic mechanical properties of bioactive glass-derived scaffolds

2020 ◽  
Vol 6 (1) ◽  
pp. 50-56
Author(s):  
Francesco Baino ◽  
Elisa Fiume
Keyword(s):  
Elastic Properties ◽  
Poisson’S Ratio ◽  
Mechanical Performance ◽  
Solid Material ◽  
Poisson's Ratio ◽  
Predictive Capability ◽  
Shear Moduli ◽  
Wide Range ◽  
Constitutive Parameters ◽  
The Relationship

AbstractPorosity is known to play a pivotal role in dictating the functional properties of biomedical scaffolds, with special reference to mechanical performance. While compressive strength is relatively easy to be experimentally assessed even for brittle ceramic and glass foams, elastic properties are much more difficult to be reliably estimated. Therefore, describing and, hence, predicting the relationship between porosity and elastic properties based only on the constitutive parameters of the solid material is still a challenge. In this work, we quantitatively compare the predictive capability of a set of different models in describing, over a wide range of porosity, the elastic modulus (7 models), shear modulus (3 models) and Poisson’s ratio (7 models) of bioactive silicate glass-derived scaffolds produced by foam replication. For these types of biomedical materials, the porosity dependence of elastic and shear moduli follows a second-order power-law approximation, whereas the relationship between porosity and Poisson’s ratio is well fitted by a linear equation.

A Progressive View on Religion and Modern Art

2015 ◽  
Vol 19 (5) ◽  
pp. 488-530
Author(s):  
Cynthia Fowler
Keyword(s):  
Cultural Identity ◽  
Modern Art ◽  
Religious Art ◽  
Wide Range ◽  
Museum Professionals ◽  
The Relationship

This article examines the Religious Art of Today exhibition, originally held in 1944 at Boston’s Institute of Modern Art and then reformulated for the Dayton Art Institute in Ohio. The exhibition was eclectic in that it included a wide range of artists and a diversity of faiths, and engaged the debate held among museum professionals about the relationship between religion and modern art. The article focuses closely on Catholic, Jewish, and Navajo art included in the exhibition. The IMA’s commitment to the figurative tradition afforded artists the opportunity to explore their identities—as Jews, as Catholics, as Navajos—using recognizable religious subjects. That the works in the exhibition were selected as representative of modern art resulted in a convergence of discourses related to modern art with those of religious/cultural identity.

scholarly journals The Effect of Sex and Age on Bone Morphology and Strength in the Metacarpus and Humerus in Beef-Cross-Dairy Cattle

Animals ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 694
Author(s):  
Michaela Gibson ◽  
Rebecca Hickson ◽  
Penny Back ◽  
Keren Dittmer ◽  
Nicola Schreurs ◽  
...  
Keyword(s):  
Dairy Cattle ◽  
Quantitative Computed Tomography ◽  
Live Weight ◽  
Peripheral Quantitative Computed Tomography ◽  
Bone Size ◽  
Limited Data ◽  
Bone Morphology ◽  
Relationship Of ◽  
The Relationship ◽  
Effect Of Age

In cattle, limited data have been reported about the relationship between live weight, bone size, and strength and how this relationship can be altered by factors such as sex and age. The aim of this study was to describe the relationship of peripheral quantitative computed tomography (pQCT)-derived parameters of bone strength and morphology with live weight, age and sex in beef-cross-dairy cattle. All animals were weighed the day before slaughter. The metacarpus and humerus were collected at slaughter and scanned at the mid-diaphysis using pQCT. Live weight was the primary explanatory variable for bone size and strength in all cohorts. However, the effect of age was significant, such that magnitude of response to liveweight was less in the 24-month-old cohort. Sex was significant within cohorts in that bulls had a shorter metacarpus than steers and heifers had a shorter metacarpus than steers at age of slaughter.

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