Pregnant women’s hepatitis B vaccination coverage in Nigeria: a national pilot cross-sectional study

Objective: To determine the hepatitis B vaccination coverage, full-dose (⩾3) coverage and the associated factors affecting uptake among pregnant women. Methods: This was a cross-sectional study among pregnant women attending antenatal care in six tertiary hospitals across all the geopolitical zones of Nigeria. Pregnant women who consented to the study completed screening questions about their hepatitis B vaccination status and coverage. The main outcome measures were hepatitis B vaccination coverage rate, dose, and factors affecting uptake. Bivariate analysis was performed by the chi-square test and conditional logistic regression analysis was used to determine variables associated with uptake of the vaccination. Odds ratios (ORs) and adjusted odds ratios (aORs) were calculated and statistical significance was accepted when p-value was < 0.05. Results: Of 159 pregnant women who completed the interview questions, 21 [13.2%, 95% confidence interval (CI) 7.9–18.5%] were vaccinated for hepatitis B for one to three doses. The numbers of doses received were: three doses (8/159, 5.0%), two doses (5/159, 3.1%), and one dose (8/159, 5.0%). The reasons for non-uptake of vaccination included: lack of awareness of the vaccine 83/138 (60.1%), inadequate access to vaccine 11/138 (8.0%), and positivity to hepatitis B virus 10/138 (7.2%). The uptake of hepatitis B vaccination was significantly affected by the level of education (OR 0.284, 95% CI 0.08–1.01, p = 0.041), but in multivariable logistic regression, adjusted for confounders, the association between hepatitis B vaccination and participants’ level of education (aOR 3.09; 95% CI 0.95–10.16; p = 0.061) did not remain significant. Conclusions: In Nigeria, the national hepatitis B vaccination coverage among pregnant women appears poor, with the full-dose coverage even poorer. The level of education was not positively associated with uptake of hepatitis B vaccination, while lack of awareness of the vaccine was the commonest reason for non-uptake. Funding: TETFund National Research Fund 2019 (grant number TETFund/DR&D/CE/NRF/STI/33).

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Social and obstetric inequalities and vaccination in pregnant women

Revista Brasileira de Enfermagem ◽

10.1590/0034-7167-2019-0099 ◽

2020 ◽

Vol 73 (suppl 4) ◽

Author(s):

Sara de Carvalho Oliveira ◽

Thales Philipe Rodrigues da Silva ◽

Gustavo Velásquez-Melendez ◽

Larissa Loures Mendes ◽

Eunice Francisca Martins ◽

...

Keyword(s):

Hepatitis B ◽

Pregnant Women ◽

Skin Color ◽

Cross Sectional Study ◽

Hepatitis B Vaccination ◽

Paid Work ◽

Sectional Study ◽

Job Market ◽

Cross Sectional ◽

Independent Variables

ABSTRACT Objectives: to analyze the association of socioeconomic level and obstetric characteristics with vaccine registration of pregnant women. Methods: cross-sectional study, performed with 480 women in puerperal. Vaccination of pregnant women was considered a dependent variable and as independent variables were age, skin color, education, steady union, paid work, and number of prenatal consultations. Association between variables was verified by the Poisson’s regression model. Results: from 480 pregnant women’s health cards, 10.63% had information on hepatitis B vaccination; 31.46% for tetanus; and 90% of the health cards had not register for influenza. There was an association of paid work and number of prenatal consultations with hepatitis B vaccination. Conclusions: lower percentages in absence of vaccination occurred in women who were in the job market and had a higher number of prenatal consultations. This suggests that socioeconomic inequalities may interfere with the vaccination of pregnant women in health services.

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Hepatitis B Vaccination Coverage Rates and Associated Factors: A Community-Based, Cross-Sectional Study Conducted in Beijing, 2019–2020

Vaccines ◽

10.3390/vaccines9101070 ◽

2021 ◽

Vol 9 (10) ◽

pp. 1070

Author(s):

Yan Liang ◽

Xinxin Bai ◽

Xinyao Liu ◽

Zheng Zhang ◽

Xinghuo Pang ◽

...

Keyword(s):

Logistic Regression ◽

Hepatitis B ◽

Vaccination Coverage ◽

Associated Factors ◽

Cross Sectional Study ◽

Hepatitis B Vaccination ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Multivariable Logistic Regression ◽

Coverage Rates

Hepatitis B vaccination coverage rates are low throughout most populations in China. Factors influencing low coverage rates, including population-specific hepatitis B vaccination barriers, may inform policies that promote vaccination. A cross-sectional survey of residents from 43 communities assessed their vaccination status and identified associated factors via uni- and multivariable logistic regression and subgroup analyses. In total, 11,280 of 36,007 respondents received a hepatitis B vaccine, indicating a 31.33% coverage rate. Multivariable logistic regression revealed non-Beijing (odds ratio (OR) = 0.81; 95% confidence interval (CI): 0.76–0.85) and residents who self-rated their health as very healthy (OR = 0.82; 95% CI: 0.68–0.99) were unlikely to be vaccinated. Farmers (OR = 1.68; 95% CI: 1.51–1.86), commerce and service workers (OR = 1.82; 95% CI, 1.63–2.04), government employees (OR = 1.56; 95% CI: 1.38–1.77), professionals and technicians (OR = 1.85; 95% CI: 1.63–2.09), and students (OR = 1.69; 95% CI: 1.10–2.59) had increased hepatitis B vaccination rates. The multivariable assessment revealed hepatitis B vaccination coverage rates are associated with confirmed or suspected family cases, vaccination unwillingness or uncertainty, and unawareness of its prevention of the hepatitis B virus. Low hepatitis B vaccination coverage rates among Beijing subpopulations highlight the need for improved strategies, including those that target specific populations.

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Influenza, Pneumococcal, and Hepatitis B Vaccination coverage and its determinants among diabetic patients at KAUH: A Single Center Cross-Sectional Study

International Journal of Medicine in Developing Countries ◽

10.24911/ijmdc.51-1602525612 ◽

2021 ◽

pp. 797-802

Author(s):

Sarah Alkhateeb ◽

Rafeef Bahafzalla ◽

Hanan Bamanie ◽

Nouran Farag ◽

Razan Alharbi ◽

...

Keyword(s):

Hepatitis B ◽

Vaccination Coverage ◽

Cross Sectional Study ◽

Hepatitis B Vaccination ◽

Diabetic Patients ◽

Sectional Study ◽

Single Center ◽

Cross Sectional

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Knowledge of preeclampsia and its associated factors among pregnant women: a possible link to reduce related adverse outcomes

BMC Pregnancy and Childbirth ◽

10.1186/s12884-019-2623-x ◽

2019 ◽

Vol 19 (1) ◽

Cited By ~ 4

Author(s):

Linda A. Fondjo ◽

Vivian E. Boamah ◽

Adelaide Fierti ◽

Dorcas Gyesi ◽

Eddie-Williams Owiredu

Keyword(s):

Logistic Regression ◽

Pregnant Women ◽

Multivariate Logistic Regression Analysis ◽

Knowledge Score ◽

Cross Sectional Study ◽

Adverse Outcomes ◽

University Hospital ◽

Cross Sectional ◽

Level Of Education ◽

Adequate Knowledge

Abstract Background Pre-eclampsia (PE) is one of the leading causes of maternal morbidity and mortality globally. Adequate knowledge about a disorder contributes greatly to its prevention, control and management. This study assessed the level of knowledge of PE and evaluated the factors associated with knowledge adequacy among pregnant women attending antenatal care at a University Hospital in Kumasi-Ghana. Methods This cross-sectional study was conducted at the University Hospital in Kumasi, Ghana. A validated closed-ended questionnaire was used to collect socio-demographic information and history of PE. Knowledge of PE was assessed based on a series of questions regarding the awareness, signs/symptoms, risk factors and complications of PE. Responses were scored percentage-wise and grouped into low (< 60%), moderate (60–80%) and high (80–100%). Knowledge score was then re-stratified into adequate (% score of ≥60%) and inadequate knowledge of PE (% score of < 60%). Results The prevalence of inadequate and adequate knowledge of PE was 88.6% (mean score = 55.5 ± 4.3%) and 11.4% (mean score = 76.3 ± 5.9%), respectively. For participants with adequate knowledge of PE, 9.1% (mean score = 67.4 ± 6.9%) and 2.3% (mean score = 85.2 ± 5.1%) had moderate and high knowledge, respectively. Using univariate logistic regression models, being older (> 35 years old) [cOR = 3.09, 95%CI (0.88–10.88), p = 0.049] and having a higher level of education (> SHS education) [cOR = 4.45, 95%CI (2.18–9.10), p < 0.0001] were significantly associated with greater odds of having adequate knowledge of PE. After controlling for potential confounders in multivariate logistic regression analysis, we found higher level of education to be independently associated with adequate knowledge of PE [aOR = 2.87, 95%CI (1.31–6.30), p = 0.008]. Conclusion The knowledge of PE among pregnant women in Ghana is low. The prominent factor that facilitates adequacy of knowledge of PE is higher level of education.

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Hepatitis B vaccination uptake in hard-to-reach populations in London: a cross-sectional study

BMC Infectious Diseases ◽

10.1186/s12879-019-3926-2 ◽

2019 ◽

Vol 19 (1) ◽

Cited By ~ 4

Author(s):

Josephine E. B. Taylor ◽

Julian Surey ◽

Jennifer MacLellan ◽

Marie Francis ◽

Ibrahim Abubakar ◽

...

Keyword(s):

Hepatitis B ◽

Cross Sectional Study ◽

Hepatitis B Vaccination ◽

Sectional Study ◽

Cross Sectional ◽

Vaccination Uptake ◽

Hard To Reach Populations

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Correlates of hepatitis B awareness and disease-specific knowledge among pregnant women in Northern and Central Uganda: a cross-sectional study

Hepatology Medicine and Policy ◽

10.1186/s41124-018-0043-6 ◽

2018 ◽

Vol 3 (1) ◽

Cited By ~ 2

Author(s):

Joan Nankya-Mutyoba ◽

Jim Aizire ◽

Fredrick Makumbi ◽

Lynn Atuyambe ◽

Ponsiano Ocama ◽

...

Keyword(s):

Hepatitis B ◽

Pregnant Women ◽

Cross Sectional Study ◽

Sectional Study ◽

Specific Knowledge ◽

Cross Sectional ◽

Disease Specific

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Hepatitis B vaccination coverage in patients with diabetes mellitus

Revista da Escola de Enfermagem da USP ◽

10.1590/s0080-623420160000200011 ◽

2016 ◽

Vol 50 (2) ◽

pp. 255-262 ◽

Cited By ~ 5

Author(s):

Clarissa Cordeiro Alves Arrelias ◽

Fernando Bellissimo-Rodrigues ◽

Letícia Cristina Lourenço de Lima ◽

Anderson Soares da Silva ◽

Nereida Kilza da Costa Lima ◽

...

Keyword(s):

Diabetes Mellitus ◽

Hepatitis B ◽

Vaccination Coverage ◽

Educational Level ◽

Health Department ◽

Cross Sectional Study ◽

Hepatitis B Vaccination ◽

Cross Sectional ◽

Patients With Diabetes

Abstract OBJECTIVE Analyze the factors associated with full hepatitis B vaccination (three doses) in patients with diabetes mellitus. METHOD Cross-sectional study, conducted in a health unit in a city in the state of São Paulo, with 255 patients on outpatient follow-up, in 2014. Data were obtained from the computerized system of the Municipal Health Department and via a structured questionnaire. A logistic regression model was used for analysis. RESULTS Full hepatitis B vaccination was noted in 13.7% of the patients and shown to be directly associated with their educational level (OR=1.30; CI: 1.07-1.57) and current or previous work as a health professional (OR=3.21; CI: 1.16-8.89). CONCLUSION Hepatitis B vaccination coverage was found to be low in patients with diabetes mellitus, indicating their vulnerability to this serious and potentially fatal disease. Higher educational level and working in the field of health were associated with better vaccination coverage.

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Vaccination coverage against hepatitis B and prevalence of HBsAg: A cross-sectional study involving 592 persons attending public screening in Abidjan

Clinics and Research in Hepatology and Gastroenterology ◽

10.1016/j.clinre.2011.02.010 ◽

2011 ◽

Vol 35 (6-7) ◽

pp. 506-507 ◽

Cited By ~ 7

Author(s):

C. Assi ◽

A. Ouattara ◽

E. Allah Kouadio ◽

M. Diakite ◽

S. Koné ◽

...

Keyword(s):

Hepatitis B ◽

Vaccination Coverage ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional

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Dry eye, its clinical subtypes and associated factors in healthy pregnancy: A cross-sectional study

PLoS ONE ◽

10.1371/journal.pone.0258233 ◽

2021 ◽

Vol 16 (10) ◽

pp. e0258233

Author(s):

Kofi Asiedu ◽

Samuel Kyei ◽

Madison Adanusa ◽

Richard Kobina Dadzie Ephraim ◽

Stephen Animful ◽

...

Keyword(s):

Logistic Regression ◽

Pregnant Women ◽

Dry Eye ◽

Associated Factors ◽

Cross Sectional Study ◽

Dry Eye Disease ◽

Eye Disease ◽

Sectional Study ◽

Cross Sectional ◽

Evaporative Dry Eye

The study determined the frequency of dry eye, its clinical subtypes and risk factors among pregnant women. This study was a hospital-based cross-sectional study of pregnant women visiting the antenatal clinic of the University of Cape Coast hospital. Clinical dry eye tests were performed along with the administration of a symptom questionnaire. Frequencies, chi-square analysis and logistic regression analyses were conducted to determine the frequency of dry eye disease, its clinical subtypes and associated factors. The prevalence of dry eye disease among the cohort of pregnant women was 82/201 (40.8% 95% confidence interval 34.3%-47.3%). Among the 82 pregnant women with dry eye disease, the frequencies of the clinical subtypes of dry eye were: evaporative dry eye [15/82(18.3%; 95% CI, 12.2%–25.2%)], aqueous deficient dry eye [10/82(12.2.%; 95% CI, 7.3%–18.3)], mixed dry eye [6/82(7.3%; 95% CI, 3.7%–11.0%)], and unclassified dry eye [51/82(62.2%; 95% CI, 52.4%–72.0%)]. Binary logistic regression analysis showed that the following factors were not significantly associated with dry eye: age, BMI, lipid profile, prolactin level, testosterone level, ocular protection index and blink rate. Only gestational age was significantly associated with dry eye disease in pregnancy. In conclusion, the current study showed that dry eye disease occurs frequently in pregnant women ranging from the first to the third trimester and it is associated with increasing gestational age. The evaporative dry eye was more common compared to the aqueous deficient dry eye, but most dry eye could not be classified.

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