scholarly journals Ossifying Lipoma in Costal Arches That Suggest Extensive Pulmonary Involvement: Case Report

2020 ◽  
Vol 13 ◽  
pp. 2632010X2090616
Author(s):  
Angélica Tobón ◽  
Nhora M Silva ◽  
Mauricio Velásquez ◽  
Eliana Morales ◽  
Saveria Sangiovanni ◽  
...  
Keyword(s):  
Subcutaneous Tissue ◽  
Clinical Manifestations ◽  
Pulmonary Involvement ◽  
Soft Tissue Tumors ◽  
The Body ◽  
Benign Tumors ◽  
Laboratory Findings ◽  
Benign Soft Tissue Tumors ◽  
Costal Arch ◽  
Ossifying Lipoma

Background: Lipomas are the most common benign soft tissue tumors in the general population. These lesions can appear on any part of the body and usually develop in the subcutaneous superficial tissue. Lipomas that show ossifying changes are very rare, representing less than 1% of the reported lipomas. They usually manifest as hard nodular lesions in the head and neck, the extremities, the sternoclavicular region, and the subcutaneous tissue in general; they are rare in the costal arches. Case presentation: We report the case of a patient with a history of multiple diseases and 2 tumor-like lesions with internal lytic areas detected in the fourth right costal arch and in the eighth left costal arc; we describe his clinical manifestations, radiological and laboratory findings as well as the pathological results and outcome. Conclusions: Ossifying lipomas are rare benign tumors with asymptomatic clinical presentation. It is important to perform an adequate radiological differentiation from other more aggressive lesions such as liposarcomas.

scholarly journals Histopathological study of soft tissue tumours in a tertiary health centre in southern part of Assam

2021 ◽  
Vol 9 (11) ◽  
pp. 3391
Author(s):  
Khadija S. Tapadar ◽  
Manoj K. Deka ◽  
R. N. Chaubey ◽  
Shah A. Sheikh ◽  
Gargi R. Choudhury ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Malignant Tumors ◽  
Soft Tissue Tumors ◽  
The Body ◽  
World Health ◽  
Vascular Tumors ◽  
Benign Tumors ◽  
Peripheral Nerve Sheath Tumors ◽  
Pleomorphic Sarcoma ◽  
Younger Age

Background: Soft tissue tumors are defined as mesenchymal proliferations which occur in the extraskeletal non-epithelial tissues of the body, excluding the viscera, coverings of brain and   lymphoreticular system. The objective of this study was to study the histopathological features of soft tissue tumors and to study the occurrence of soft tissue tumors in relation to age, sex and anatomical site.Methods: This study comprised of 89 cases studied over a period of two years. All soft tissue tumors, their gross features, microscopic findings were analysed in detail. Soft tissue tumors were divided into benign and malignant categories and further sub typing were done according to World Health Organization (WHO) classification. The distribution of soft tissue tumors according to the age, sex and site of occurrence was studied.Results: Out of 89 cases of soft tissue tumors, 76 cases were benign, 4 cases belonged to intermediate category and 9 cases were malignant. Adipocytic tumors formed the largest group constituting 39 cases. Vascular tumors were the second commonest (26 cases) followed by peripheral nerve sheath tumors (11 cases). The benign tumors were seen in younger age as compared to malignant tumors. Malignant soft tissue tumors was seen to be more common in male than female and pleomorphic sarcoma and liposarcoma was commonest (3 cases each).Conclusions: Benign tumors were more common than malignant. The most common benign tumors were lipoma followed by hemangioma and schwannoma. The most common malignant tumor was pleomorphic sarcoma. The benign tumors were seen in younger age as compared to malignant tumors.

scholarly journals Magnetic Resonance Imaging Appearance of Schwannomas from Head to Toe: A Pictorial Review

2017 ◽  
Vol 7 ◽  
pp. 38 ◽  
Author(s):  
Jamie Crist ◽  
Jacob R Hodge ◽  
Matthew Frick ◽  
Fiona P Leung ◽  
Eugene Hsu ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Soft Tissue ◽  
Neurofibromatosis Type ◽  
Soft Tissue Tumors ◽  
The Body ◽  
Resonance Imaging ◽  
Pictorial Review ◽  
Benign Soft Tissue Tumors ◽  
Mri Characteristics

Schwannomas are benign soft-tissue tumors that arise from peripheral nerve sheaths throughout the body and are commonly encountered in patients with neurofibromatosis Type 2. The vast majority of schwannomas are benign, with rare cases of malignant transformation reported. In this pictorial review, we discuss the magnetic resonance imaging (MRI) appearance of schwannomas by demonstrating a collection of tumors from different parts of the body that exhibit similar MRI characteristics. We review strategies to distinguish schwannomas from malignant soft-tissue tumors while exploring the anatomic and histologic origins of these tumors to discuss how this correlates with their imaging findings. Familiarity with the MRI appearance of schwannomas can help aid in the differential diagnosis of soft-tissue masses, especially in unexpected locations.

scholarly journals A case of colonic intussusception and obstruction secondary to giant colonic lipoma

2020 ◽  
Vol 2020 (10) ◽  
Author(s):  
Yi Ying Law ◽  
Rhea Patel ◽  
Marianne Cusick ◽  
Jeffrey L Van Eps
Keyword(s):  
Bowel Obstruction ◽  
Large Bowel ◽  
Transverse Colon ◽  
Right Hemicolectomy ◽  
Large Bowel Obstruction ◽  
Soft Tissue Tumors ◽  
The Body ◽  
Common Location ◽  
Benign Soft Tissue Tumors ◽  
Colonic Lipoma

Abstract Lipomas are benign soft tissue tumors found throughout the body including the gastrointestinal (GI) tract. Colonic lipomas are typically asymptomatic, incidentally identified during endoscopy or at the time of autopsy. However, giant lipomas larger than 4 cm usually manifest symptoms such as abdominal pain, obstruction, melena or intussusception. The transverse colon is the least common location for colonic lipoma. We report on a 54-year-old man with acute large bowel obstruction secondary to a long segment colo-colonic intussusception from a giant lipoma originating in the transverse colon. The diagnosis was suggested by advanced imaging and confirmed on endoscopy. He was treated successfully by laparoscopic extended right hemicolectomy with ileocolonic anastomosis. This case highlights the complexity of presentation and surgical management of large bowel obstruction and colonic intussusception, as well as the rare entity of giant colonic lipoma.

scholarly journals PEComa: A Perivascular Epithelioid Cell Tumor in the Liver—A Case Report and Review of the Literature

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Faseeh Khaja ◽  
Allison Carilli ◽  
Said Baidas ◽  
Aravindhan Sriharan ◽  
Shanedelle Norford
Keyword(s):  
Malignant Tumors ◽  
Mtor Inhibitors ◽  
Epithelioid Cell ◽  
Soft Tissue Tumors ◽  
Cell Tumor ◽  
The Body ◽  
Benign Tumors ◽  
Review Of The Literature ◽  
Perivascular Epithelioid Cell ◽  
Perivascular Epithelioid Cell Tumors

Perivascular epithelioid cell tumors are soft tissue tumors that can occur in various locations in the body whose incidence is rising. Hepatic PEComas are quite rare and diagnosis involves positivity of Melan-A and HMB45 on immunohistochemistry. Usual treatment is surgery for benign tumors and chemotherapy including mTOR inhibitors for malignant tumors. Here we discuss the radiological and pathological diagnosis, evaluation, and management of a hepatic PEComa. We describe a 51-year-old patient who was diagnosed incidentally after unusual physical exam findings.

scholarly journals A young woman with multiple soft tissue tumors in various parts of the body, (Extra Abdominal Fibromatosis and Lymphangioma in both Axillas)

1970 ◽  
Vol 1 (1) ◽  
pp. 29-32
Author(s):  
MD A Kalam ◽  
F Ahmad ◽  
M Hassan ◽  
Md Nasiruddin ◽  
SA Rahman ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Lymphatic System ◽  
Soft Tissue Tumors ◽  
The Body ◽  
Soft Tissue Tumours ◽  
Benign Soft Tissue Tumors ◽  
History Of ◽  
Infiltrative Growth Pattern ◽  
Well Differentiated ◽  
Aggressive Clinical Behavior

The term fibromatosis refers to a group of benign soft tissue tumors (fibromas), which have certain characteristics in common, including absence of cytologic and clinical malignant features, a histology consistent with proliferation of well-differentiated fibroblasts, an infiltrative growth pattern, and aggressive clinical behavior with frequent local recurrence. Lymphangiomas are malformations of the lymphatic system, which is the network of vessels responsible for returning to the venous system of excess fluid from tissues. Here we report a case of 30 years old lady with history of multiple soft tissue tumours in thigh, axilla and abdomen. On physical examination the swelling of the thigh and abdomen were firm and those of axilla were soft. All the tumours were excised surgically and diagnosis of thigh swelling was fibromatosis and that of axilla was lymphangioma, on histopathology.DOI: http://dx.doi.org/10.3329/bdjps.v1i1.6490Bangladesh Journal of Plastic Surgery (2010) Vol. 1 (1) pp.29-32

scholarly journals The First Case Treated with Larotrectinib of a Novel TMTC2-NTRK3 Fusion Undifferentiated High-Grade Pleomorphic Sarcoma of the Chest

2021 ◽  
Author(s):  
Chujie Bai ◽  
Lu Zhang ◽  
Yaohui Wang ◽  
Taiyan Guo ◽  
Xia You ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Clinical Manifestations ◽  
Soft Tissue Tumors ◽  
The Body ◽  
High Grade ◽  
Pleomorphic Sarcoma ◽  
First Case ◽  
Painless Mass ◽  
Almost All ◽  
Next Generation Sequencing Ngs

Abstract Undifferentiated high-grade pleomorphic sarcoma (UPS) is a rare soft tissue sarcoma (STS) of mesenchymal origin, particularly the extremities and retroperitoneum, meanwhile it has been reported in almost all parts of the body. UPS is highly invasive and has a poor prognosis due to its clinical manifestations of painless mass and deep tumor site, which are usually found at an advanced stage. Patients with UPS tend to have a lower 5-year survival rate than patients with other types of STS. Recently, NTRK fusions were detected in many cancer types, such as thyroid cancer, colorectal cancer, non-small cell lung cancer, soft tissue tumors, uterine sarcomas, and melanomas. However, the mutation frequency of NTRK fusion in all cancers is only 0.1-1%. Targeted therapy with NTRK inhibitors, such as Larotrectinib and Entrectinib, leads to a response in most patients with NTRK1/2/3 gene fusion-positive tumors. Herein, we present a 68-years old man diagnosed with stage IIIA (T2N0M0G3) UPS. Next-generation sequencing (NGS) revealed a novel TMTC2-NTRK3 fusion. The NTRK3 positivity was also detected by immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). He had a response to Larotrectinib. This report broadens the spectrum of NTRK fusions in UPS and highlights a new target for treatment.

scholarly journals Significance of Coagulation and Fibrinolysis Markers for Benign and Malignant Soft Tissue Tumors

2020 ◽  
Author(s):  
Kunihiro Asanuma ◽  
Tomoki Nakamura ◽  
Tomohito Hagi ◽  
Takayuki Okamoto ◽  
Kouji Kita ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Malignant Tumors ◽  
Characteristic Curve ◽  
Soft Tissue Tumors ◽  
Clinicopathological Parameters ◽  
Diagnostic Tools ◽  
Benign Tumors ◽  
Benign Soft Tissue Tumors ◽  
Significant Difference ◽  
Coagulation And Fibrinolysis

Abstract Background: The intimate relationship between coagulation and fibrinolysis in malignant tumors is a well-known phenomena, with the malignant phenotype enhancing coagulation and fibrinolysis. We hypothesized that soft tissue sarcoma (STS) affects the expression of coagulation and fibrinolysis markers, which could be used to distinguish STS from benign soft tissue tumors. We analyzed the correlations between plasma levels of D-dimer (DD), plasmin-α2 plasmin inhibitor complex (PIC), soluble fibrin (SF), and thrombin-antithrombin III complex (TAT) in benign soft tissue tumors and STS to elucidate whether these markers can be used to predict STS.Methods: Plasma DD, PIC, SF and TAT levels in primary soft tissue tumors (benign, 67, STS 68) were measured before biopsy or treatment. The marker levels were analyzed and compared to various clinicopathological parameters.Results: In malignancy (STS), the average DD, PIC and SF levels were significantly higher than in benign tumors. Multivariate logistic analysis of continuous variables indicated that only PIC exhibited a significant difference (OR: 24.5, 95%CI: 3.55-170, p=0.0012). Receiver operating characteristic curve analysis produced area under the curve values for DD: 0.691, PIC: 0.784, SF: 0.734 and TAT: 0.588. Youden’s index was used to establish thresholds of 0.37 (DD), 0.80 (PIC), 0.90 (SF) and 0.82 (TAT). Threshold values for PIC and SF indicated high specificity (0.881, 0.791) and high positive predictive value (0.818, 0.745), respectively The highest accuracy value among the markers was observed for PIC (0.704). Significant differences in multivariate analysis of binary variables were demonstrated by categorizing low and high groups based on their threshold, PIC (≥0.80) (OR: 3.36, 95%CI: 1.19-9.43, p=0.0212) and SF (≥0.90) (OR: 2.63, 95%CI: 1.04-6.66, p=0.0404) . Conclusions: Of the coagulation and fibrinolysis markers studied, increased PIC levels were related to STS and over 0.80 PIC was the most suitable for the prediction of STS, which, along with other diagnostic tools, represents a helpful subsidiary tool for the prediction of STS.

Extensive Lipoma of the Foot

2003 ◽  
Vol 93 (5) ◽  
pp. 402-405 ◽  
Author(s):  
Jane Pontious ◽  
Lorne A. Zielaskowski ◽  
Glenda King
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Tumors ◽  
The Body ◽  
Lateral Aspect ◽  
Benign Soft Tissue Tumors

Although lipomas are the most common benign soft-tissue tumors found in the body, they are not commonly found in the foot. This case study concerns an unusually large lipoma on the plantar lateral aspect of the foot that was successfully excised without any sign of recurrence. (J Am Podiatr Med Assoc 93(5): 402-405, 2003)

scholarly journals Intraoral Lipoma of Palatal Mucosa

2016 ◽  
Vol 6 (2) ◽  
pp. 142-144
Author(s):  
Priyanka Tidke Munde ◽  
Prashant B Munde ◽  
Pradnya Jadhav
Keyword(s):  
Soft Tissue ◽  
Oral Cavity ◽  
Soft Tissue Tumors ◽  
The Body ◽  
Frequency Of Occurrence ◽  
Posterior Aspect ◽  
Benign Soft Tissue Tumors ◽  
Single Well ◽  
Palatal Mucosa

ABSTRACT Lipomas are most common, benign, soft tissue tumors in the body; however, they are rarely seen in the oral cavity. Intraoral lipomas are seen as benign, well-encapsulated swelling without pain with added yellowish tinge. We are presenting a case of an intraoral lipoma where the 22-year-old female presented a single well-encapsulated swelling in the posterior aspect of the palate on left side. The purpose of this report is to emphasize the need for dentists to be aware of frequency of occurrence of intraoral lipoma. How to cite this article Munde PT, Munde PB, Jadhav P. Intraoral Lipoma of Palatal Mucosa. J Contemp Dent 2016;6(2):142-144.

scholarly journals CAPABILITIES OF COMPLEX SONOGRAPHIC IMAGING FOR BENIGN SOFT TISSUE TUMORS OF FOOT AND ANKLE

2010 ◽  
Vol 16 (1) ◽  
pp. 62-67
Author(s):  
E. N. Pugacheva ◽  
N. A. Koryshkov ◽  
L. V. Koryshkova
Keyword(s):  
Soft Tissue ◽  
Ultrasound Examination ◽  
Soft Tissue Tumors ◽  
Benign Tumors ◽  
Diagnostic Efficiency ◽  
Foot And Ankle ◽  
Benign Soft Tissue Tumors ◽  
Ultrasound Findings ◽  
Sonographic Imaging ◽  
Morphological Patterns

The article presents the results of the complex ultrasound examination for 49 patients with benign soft tissue tumors of the foot and ankle. Ultrasound findings of benign tumors have been compared and systematized taking into account their morphological patterns at the additional use of dopplerography. High diagnostic efficiency of this complex ultrasound examination has been shown.

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