scholarly journals The Utility of Echocardiography for Non-ST-Segment Elevation Myocardial Infarction: A Retrospective Study

2019 ◽  
Vol 36 (2) ◽  
pp. 121-129
Author(s):  
Edward T. Ha ◽  
Marc Cohen ◽  
Paul J. Fields ◽  
Jessie Van Daele ◽  
Theodore J. Gaeta
Keyword(s):  
Myocardial Infarction ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Primary Diagnosis ◽  
Integrative Approach ◽  
St Segment Elevation ◽  
Segment Elevation Myocardial Infarction ◽  
St Segment ◽  
Demographic Attributes ◽  
The Impact

Objective: The objectives were to assess factors associated with a higher likelihood of predicting acute coronary atherothrombosis (ACA) in non-ST-segment elevation myocardial infarction (NSTEMI), evaluate the impact of adding echocardiographic data, and develop an algorithm that would reduce overutilization of emergent angiography. Methods: Data were retrospectively analyzed on a patient cohort presenting to an emergency department of an urban community hospital with NSTEMI from October 1, 2015, to July 31, 2018. The inclusion criterion was any adult patient with a first-time, primary diagnosis of NSTEMI without high-risk features. The main outcome variables were the presence of ACA on angiography. Results: Seventy-three patients with NSTEMI were included in this study. Logistic regression analysis identified the following independent variables useful for predicting ACA: age, wall motion abnormality on echo, and levels of low-density lipoprotein. The model’s overall fit was highly significant ( P = .0012). Conclusion: An integrative approach was demonstrated for the management of patients with NSTEMI presenting to the hospital. Although the positive predictive value of echo in predicting ACA was limited, when combined with demographic attributes and risk factors, it proved to be successful in determining the need for angiography in patients with NSTEMI.

scholarly journals Profil lipid pada wanita dengan sindrom koroner akut

2016 ◽  
Vol 8 (2) ◽  
Author(s):  
Ronaldi . ◽  
Ike Adriana ◽  
Monique Rotty ◽  
Reginald L. Lefrandt ◽  
Agnes L. Panda
Keyword(s):  
Myocardial Infarction ◽  
High Density Lipoprotein ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Low Density ◽  
St Segment Elevation ◽  
Segment Elevation Myocardial Infarction ◽  
St Segment ◽  
St Elevation ◽  
The Mean

Abstract: Females with acute coronary syndrome (ACS) display different characteristics from the opposite gender. Currently, only limited data were available regarding the characteristic of ACS in females, especially in Manado. This study aimed to obtain the lipid profile of females with ACS at Prof. Dr. R. D. Kandou Hospital Manado in 2012-2013. This was a descriptive retrospective study with a cross sectional design. Subjects were all female patients with ACS who were admitted to Prof. Dr. R. D. Kandou Hospital Manado from January 2012 to December 2013. Data were collected based on the medical record. Exclusion criteria included incomplete data and non-ACS as the main diagnosis. There were 81 women as subjects in this study. The mean age was 61.59±10.78 years. Unstable angina pectoris, non-ST elevation myocardial infarction, ST elevation myocardial infarction were found in 38 (46.9%), 15 (18.5%), and 28 (34.6%) patients consecutively. Mean value of total cholesterol, low density lipoprotein (LDL), high density lipoprotein (HDL), and trygliserida levels were as follows: 218.17±48.88, 145.91±47.30, 39.72±15.99, and 153±65.55 mg/dl. High level of total cholesterol, LDL, and trygliserida were found in 52 (64.2%), 50 (61.7%), 14 (17.3%) patients consecutively meanwhile low HDL level was found in 51(63%) patients. Diabetes mellitus and hypertension were found in 24 (29.6%) and 58 (71.6%) patients. The mean length of stay was 8.44±4.36 days.Keywords: female, lipid profile, acute coronary syndromeAbstrak: Wanita dengan sindrom koroner akut (SKA) menampilkan karakteristik yang berbeda daripada laki-laki dengan SKA. Sampai saat ini, masih tersedia sedikit data mengenai karakteristik SKA pada wanita. Penelitian ini bertujuan mendapatkan gambaran profil lipid pada wanita dengan SKA yang dirawat di RSUP Prof. Dr. R. D. Kandou. Jenis penelitian ini deskriptif retrospektif dengan desain potong lintang. Subyek penelitian ialah pasien wanita dengan SKA yang dirawat di RSUP Prof. Dr. R. D. Kandou, Manado dari Januari 2012-Desember 2013. Data dikumpulkan dari rekam medis. Kriteria eksklusi meliputi data yang tidak lengkap dan diagnosis selain SKA sebagai diagnosis utama. Hasil penelitian mendapatkan subyek 81 pasien wanita dengan usia rata-rata 61,59±10,78 tahun. Angina pektoris tak stabil ditemukan pada 38 pasien (46,9%), non-ST segment elevation myocardial infarction pada 15 pasien (18,5%), dan ST segment elevation myocardial infarction pada 28 pasien (34,6%). Kadar rerata kolesterol total, low density lipoprotein (LDL), high density lipoprotein (HDL), dan trigliserida ialah berturut-turut 218,17±48,88, 145,91±47,30, 39,72±15,99, dan 153±65,55 mg/dl. Kadar kolesterol total, LDL, trigliserida yang tinggi ditemukan berturut-turut pada 52 pasien (64,2%), 50 pasien (61,7%), dan 14 pasien (17,3%) sedangkan kadar HDL yang rendah ditemukan pada 51 pasien (63%). Diabetes melitus dan hipertensi ditemukan pada 24 pasien (29,6%) dan 58 pasien (71,6%). Rerata lama perawatan di rumah sakit ialah 8,44±4,36 hari.Kata kunci: wanita, profil lipid, sindrom koroner akut

Daily, Monthly, and Seasonal Pattern of ST-Segment Elevation Myocardial Infarction (STEMI) Occurrence in Western Iran; a CrossSectional Study

2021 ◽  
Author(s):  
Nahid Salehi ◽  
Reza Heidari Moghadam ◽  
Alireza Rai ◽  
Nafiseh Montazeri ◽  
Javad Azimivghar ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Seasonal Pattern ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
P Value ◽  
Cross Sectional ◽  
St Segment Elevation ◽  
Segment Elevation Myocardial Infarction ◽  
St Segment

Introduction: Acute myocardial infarction (AMI) is a leading cause of death and disability worldwide. Determining seasonal pattern of AMI may contribute to disease prevention and better treatment. Objective: The present study was conducted to investigate daily, monthly, and seasonal pattern for symptoms҆ onset in the patients with ST-segment elevation myocardial infarction (STEMI), and also other possible associated factors. Methods: This cross-sectional study was conducted on 777 patients diagnosed with STEMI admitted at the Imam Ali Cardiovascular Hospital affiliated with Kermanshah University of Medical Sciences (KUMS), Kermanshah province, Iran from March 2018 to February 2019. Data were collected using a checklist developed based on the study's objectives. Differences between subgroups were assessed using one-way analysis of variance (ANOVA) followed by Tukeys҆ post‐hoc test and Chi-Square test (or Fishers҆ exact test). Results: Out of 777 patients, 616 (79.3%) of them were male. Mean age of the patients was (mean±SD) equal to 60.93±12.86 years old. Occurrence of STEMI was most common in winter (38.4%), followed by autumn (27.8%), spring (22.9%), and summer (10.9%), respectively. Monthly occurrence of AMI was at the highest level in January (10.8%) and December (9.9%), and it was at the lowest level in July (4.9 %). Most patients were admitted on Fridays (15.8%) and Wednesdays (15.6%). Hypercholesterolemia, prior congestive heart failure (CHF), prior MI, prior stroke, prior atrial fibrillation (AF), low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglycerides, total cholesterol, creatine phosphokinase (CPK), and creatine kinase myocardial band (CK-MB) were significantly associated with seasonal pattern of STEMI (p-value<0.05). Conclusions: Results of the present study on Iranian patients with STEMI revealed that AMI occurred more frequently on Wednesdays and Fridays and during winter from December to January compared to the other days of the week, months, and seasons.

Malnutrition and biological frailty are independent and complementary predictors of one-year mortality in women after primary angioplasty for ST-segment elevation myocardial infarction

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
R Arroyo-Espliguero ◽  
M.C Viana-Llamas ◽  
A Silva-Obregon ◽  
A Estrella-Alonso ◽  
C Marian-Crespo ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Mortality Rate ◽  
Primary Angioplasty ◽  
Prognostic Impact ◽  
St Segment Elevation ◽  
Segment Elevation Myocardial Infarction ◽  
Kaplan Meier ◽  
St Segment ◽  
One Year ◽  
The Impact

Abstract Background Malnutrition and sarcopenia are common features of frailty. Prevalence of frailty among ST-segment elevation myocardial infarction (STEMI) patients is higher in women than men. Purpose Assess gender-based differences in the impact of nutritional risk index (NRI) and frailty in one-year mortality rate among STEMI patients following primary angioplasty (PA). Methods Cohort of 321 consecutive patients (64 years [54–75]; 22.4% women) admitted to a general ICU after PA for STEMI. NRI was calculated as 1.519 × serum albumin (g/L) + 41.7 × (actual body weight [kg]/ideal weight [kg]). Vulnerable and moderate to severe NRI patients were those with Clinical Frailty Scale (CFS)≥4 and NRI&lt;97.5, respectively. We used Kaplan-Meier survival model. Results Baseline and mortality variables of 4 groups (NRI-/CFS-; NRI+/CFS-; NRI+/CFS- and NRI+/CFS+) are depicted in the Table. Prevalence of malnutrition, frailty or both were significantly greater in women (34.3%, 10% y 21.4%, respectively) than in men (28.9%, 2.8% y 6.0%, respectively; P&lt;0.001). Women had greater mortality rate (20.8% vs. 5.2%: OR 4.78, 95% CI, 2.15–10.60, P&lt;0.001), mainly from cardiogenic shock (P=0.003). Combination of malnutrition and frailty significantly decreased cumulative one-year survival in women (46.7% vs. 73.3% in men, P&lt;0.001) Conclusion Among STEMI patients undergoing PA, the prevalence of malnutrition and frailty are significantly higher in women than in men. NRI and frailty had an independent and complementary prognostic impact in women with STEMI. Kaplan-Meier and Cox survival curves Funding Acknowledgement Type of funding source: None

scholarly journals Evaluation of two highly effective lipid-lowering therapies in subjects with acute myocardial infarction

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Aline Klassen ◽  
Andrea Tedesco Faccio ◽  
Carolina Raissa Costa Picossi ◽  
Priscilla Bento Matos Cruz Derogis ◽  
Carlos Eduardo dos Santos Ferreira ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Lipid Lowering ◽  
Low Density Lipoprotein Cholesterol ◽  
Residual Cardiovascular Risk ◽  
St Segment Elevation ◽  
Lipidomic Analysis ◽  
St Segment ◽  
Highly Effective

AbstractFor cardiovascular disease prevention, statins alone or combined with ezetimibe have been recommended to achieve low-density lipoprotein cholesterol targets, but their effects on other lipids are less reported. This study was designed to examine lipid changes in subjects with ST-segment elevation myocardial infarction (STEMI) after two highly effective lipid-lowering therapies. Twenty patients with STEMI were randomized to be treated with rosuvastatin 20 mg QD or simvastatin 40 mg combined with ezetimibe 10 mg QD for 30 days. Fasting blood samples were collected on the first day (D1) and after 30 days (D30). Lipidomic analysis was performed using the Lipidyzer platform. Similar classic lipid profile was obtained in both groups of lipid-lowering therapies. However, differences with the lipidomic analysis were observed between D30 and D1 for most of the analyzed classes. Differences were noted with lipid-lowering therapies for lipids such as FA, LPC, PC, PE, CE, Cer, and SM, notably in patients treated with rosuvastatin. Correlation studies between classic lipid profiles and lipidomic results showed different information. These findings seem relevant, due to the involvement of these lipid classes in crucial mechanisms of atherosclerosis, and may account for residual cardiovascular risk.Randomized clinical trial: ClinicalTrials.gov, NCT02428374, registered on 28/09/2014.

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