scholarly journals Battle of the Clones: Somatic Genetic Rescue of Pediatric Patients With MDS Teaches Us About MDS Biology in 2021 and a Platform for the Future

2022 ◽  
Vol 19 (1) ◽  
Author(s):  
Amy DeZern
2019 ◽  
Author(s):  
Mehdi Chihi ◽  
Oliver Gembruch ◽  
Marvin Darkwah Oppong ◽  
Bixia Chen ◽  
Thiemo Florian Dinger ◽  
...  

2021 ◽  
Vol 12 (9) ◽  
pp. 66-68
Author(s):  
Anjana Karmacharya ◽  
Dashrath Kafle

Background: Mesiodens are supernumerary teeth present in the midline of the maxilla. Aims and Objective: The present study was conducted to know the prevalence of mesiodens among children aged 5 to 14 years in Pokhara, Nepal. Materials and Methods: Data was collected from 1194 orthodontic patients coming to the department of Dentistry, in Manipal Teaching Hospital from 2009 till 2019. The files were reviewed to know the prevalence, demography and the complications associated with the presence of mesiodens. Results: Our results showed that the prevalence of mesiodens was 2.84% in our population. The prevalence was significantly more among males. Children aged 10-14 years presented more than the children aged 5-10 years. Though, there were complications associated with the presence of mesiodens, none of them were symptomatic. Conclusions: Mesiodens is the most common form of supernumerary teeth in the pediatric patients which occurs as a result of genetic and environmental factors. Their early diagnosis can reduce the treatment required and therefore prevent development of associated problems in the future.


PEDIATRICS ◽  
1975 ◽  
Vol 55 (6) ◽  
pp. 896-896
Author(s):  
Simeon David

There has been a recent trend to treating more and more pediatric patients with chronic diseases on an ambulatory basis. This is true of both hemophilia1,2 and cystic fibrosis. In a recent report Drs. Rucker and Harrison3 presented data on 62 patients who received a total of 127 outpatient intravenous antibiotic courses for bronchopulmonary infections. Despite their success in keeping slightly more than two thirds of their patients out of the hospital, I think that they might be more successful in the future if the following points are considered.


2006 ◽  
Vol 17 (10) ◽  
pp. 722-732 ◽  
Author(s):  
Daniel L. Monin ◽  
Ken Kazahaya ◽  
Kevin H. Franck

Crystal Device Integrity Testing System (CITS), the first commercially available testing system of its type, allows rapid assessment of cochlear implant function by measuring averaged electrode voltages—the scalp-recorded fields generated by electrode currents. We describe our experience performing routine integrity tests on 44 pediatric cochlear implant patients using the CITS. We present our findings focusing on the monopolar and common ground scans to provide a framework from which CITS scans can be evaluated in the future. We also describe selected cases in which abnormal results using the CITS influenced clinical treatment, demonstrating the utility of performing routine integrity tests.


Open Medicine ◽  
2018 ◽  
Vol 13 (1) ◽  
pp. 366-373 ◽  
Author(s):  
Liang Chen ◽  
Jun Zhang ◽  
Guoshi Pan ◽  
Xia Li ◽  
Tianwu Shi ◽  
...  

AbstractBackgroundCuffed and uncuffed endotracheal tubes are commonly used for pediatric patients in surgery and emergency situations. It is still controversial which approach should be adopted. The purpose of the study was to compare the application of cuffed and uncuffed endotracheal tubes in pediatric patients.MethodsWe searched PubMed, Web of Science and Cochrane Library for clinical trials, which compared the two applications in children. The study characteristics and clinical data were summarized by two independent reviewers. Meta-analysis of the data was done using Revman 5.3 software.Results6 studies with 4141 cases were included in this meta-analysis. The pooling analysis showed that more patients need tube changes in uncuffed than cuffed tubes (OR: 0.07, 95% CI: 0.05-0.10, P < 0.00001). However, there were no differences on intubation duration, reintubation occurrence, accidental extubation rate, croup occurrence and racemic epinephrine use during the intubation process. Also we didn’t find any differences on laryngospasm and stridor occurrence after extubation.ConclusionsOur study demonstrated that uncuffed endotracheal tubes increased the need for tube changes. Other incidences or complications between the two groups had no differences. Cuffed tubes may be an optimal option for pediatric patients. But more trials are needed in the future.


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