scholarly journals Adult lung function and long-term air pollution exposure. ESCAPE: a multicentre cohort study and meta-analysis

2014 ◽  
Vol 45 (1) ◽  
pp. 38-50 ◽  
Author(s):  
Martin Adam ◽  
Tamara Schikowski ◽  
Anne Elie Carsin ◽  
Yutong Cai ◽  
Benedicte Jacquemin ◽  
...  
Keyword(s):  
Air Pollution ◽  
Lung Function ◽  
Meta Analysis ◽  
Ambient Air ◽  
Coarse Fraction ◽  
Forced Expiratory Volume ◽  
Ambient Air Pollution ◽  
Longitudinal Change ◽  
Pollution Effects

The chronic impact of ambient air pollutants on lung function in adults is not fully understood. The objective of this study was to investigate the association of long-term exposure to ambient air pollution with lung function in adult participants from five cohorts in the European Study of Cohorts for Air Pollution Effects (ESCAPE).Residential exposure to nitrogen oxides (NO2, NOx) and particulate matter (PM) was modelled and traffic indicators were assessed in a standardised manner. The spirometric parameters forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) from 7613 subjects were considered as outcomes. Cohort-specific results were combined using meta-analysis.We did not observe an association of air pollution with longitudinal change in lung function, but we observed that a 10 μg·m−3 increase in NO2 exposure was associated with lower levels of FEV1 (−14.0 mL, 95% CI −25.8 to −2.1) and FVC (−14.9 mL, 95% CI −28.7 to −1.1). An increase of 10 μg·m−3 in PM10, but not other PM metrics (PM2.5, coarse fraction of PM, PM absorbance), was associated with a lower level of FEV1 (−44.6 mL, 95% CI −85.4 to −3.8) and FVC (−59.0 mL, 95% CI −112.3 to −5.6). The associations were particularly strong in obese persons.This study adds to the evidence for an adverse association of ambient air pollution with lung function in adults at very low levels in Europe.

scholarly journals Chronic effects of air pollution on lung function after lung transplantation in the Systems prediction of Chronic Lung Allograft Dysfunction (SysCLAD) study

2016 ◽  
Vol 49 (1) ◽  
pp. 1600206 ◽  
Author(s):  
Meriem Benmerad ◽  
Rémy Slama ◽  
Karine Botturi ◽  
Johanna Claustre ◽  
Antoine Roux ◽  
...  
Keyword(s):  
Air Pollution ◽  
Lung Function ◽  
Lung Transplantation ◽  
Air Pollutants ◽  
Chronic Exposure ◽  
Ambient Air ◽  
Forced Expiratory Volume ◽  
Ambient Air Pollution ◽  
Lung Transplant Recipients

An irreversible loss in lung function limits the long-term success in lung transplantation. We evaluated the role of chronic exposure to ambient air pollution on lung function levels in lung transplant recipients (LTRs).The lung function of 520 LTRs from the Cohort in Lung Transplantation (COLT) study was measured every 6 months. The levels of air pollutants (nitrogen dioxide (NO2), particulate matter with an aerodynamic cut-off diameter of x µm (PMx) and ozone (O3)) at the patients' home address were averaged in the 12 months before each spirometry test. The effects of air pollutants on forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) in % predicted were estimated using mixed linear regressions. We assessed the effect modification of macrolide antibiotics in this relationship.Increased 12-month levels of pollutants were associated with lower levels of FVC % pred (−2.56%, 95% CI −3.86–−1.25 for 5 µg·m−3of PM10; −0.75%, 95% CI −1.38–−0.12 for 2 µg·m−3of PM2.5and −2.58%, 95% CI −4.63–−0.53 for 10 µg·m−3of NO2). In patients not taking macrolides, the deleterious association between PM and FVC tended to be stronger and PM10was associated with lower FEV1.Our study suggests a deleterious effect of chronic exposure to air pollutants on lung function levels in LTRs, which might be modified with macrolides.

Ambient air pollution exposure and lung function assessment of filling station attendants in Ibadan, Nigeria

2019 ◽  
Vol 34 (2) ◽  
pp. 211-218
Author(s):  
Toluwanimi Mobolade Oni ◽  
Godson R.E.E. Ana
Keyword(s):  
Air Pollution ◽  
Lung Function ◽  
Air Pollutants ◽  
Ambient Air ◽  
Forced Expiratory Volume ◽  
Ambient Air Pollution ◽  
World Health ◽  
Health Administration ◽  
Cross Sectional ◽  
Filling Station

Abstract Background There is an increasing range of adverse health effects associated with air pollution at very low concentrations. Few studies have assessed respiratory parameters among filling station attendants. Objectives This study assessed air pollutants; particulate matter (PM10) and total volatile organic compounds (TVOC) concentrations at filling stations as well as determined forced expiratory volume in one second (FEV1) and peak expiratory flow rate (PEFR) levels among filling station attendants. Methods A cross-sectional study was conducted to assess PM10 and TVOC concentrations at 20 systematically selected filling stations in Ibadan North Local Government Area, Ibadan for 2 months using a Thermo Scientific pDR 1500 PM10 monitor and SF2000-TVOC meter. FEV1 and PEFR levels were measured in order to assess the effect of exposure to PM10 and TVOC on lung function of 100 filling station attendants using a PIKO-1 Electronic peakflow/FEV1 meter. Results Total mean PM10 concentrations (μg/m3) in the morning (43.7±16.5) and afternoon (27.8±7.9) were significantly lower (p<0.01) than the World Health Organization (WHO) guideline limit (50 μg/m3). Total mean TVOC concentrations (ppm) in the morning (12.0±3.4) and afternoon (5.6±2.4) were however significantly higher (p<0.01) than the Occupational Safety and Health Administration (OSHA) guideline limit (3 ppm). Mean FEV1 for filling station attendants was 1.63±0.39 and PEFR was 171.7±45.9. Conclusion Filling stations are hotspots for the emission of VOCs and PM10. However, filling station attendants in this study are at risk of exposure to high concentrations of VOCs but not PM10. FEV1 and PEFR values among filling station attendants were very low which could possibly be attributed to extended exposure to air pollutants. Regular medical examinations should also be conducted on filling station attendants in order to aid early detection of deviations in their health status.

scholarly journals Long term exposure to ambient air pollution and incidence of acute coronary events: prospective cohort study and meta-analysis in 11 European cohorts from the ESCAPE Project

BMJ ◽  
2014 ◽  
Vol 348 (jan21 3) ◽  
pp. f7412-f7412 ◽  
Author(s):  
G. Cesaroni ◽  
F. Forastiere ◽  
M. Stafoggia ◽  
Z. J. Andersen ◽  
C. Badaloni ◽  
...  
Keyword(s):  
Air Pollution ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Meta Analysis ◽  
Ambient Air ◽  
Ambient Air Pollution ◽  
Coronary Events

Long-Term Effects of Ambient Air Pollution on Lung Function

Epidemiology ◽  
2008 ◽  
Vol 19 (5) ◽  
pp. 690-701 ◽  
Author(s):  
Thomas Götschi ◽  
Joachim Heinrich ◽  
Jordi Sunyer ◽  
Nino Künzli
Keyword(s):  
Air Pollution ◽  
Lung Function ◽  
Ambient Air ◽  
Ambient Air Pollution ◽  
Long Term Effects

scholarly journals Long-term exposure to ambient air pollution and incidence of brain tumor: the European Study of Cohorts for Air Pollution Effects (ESCAPE)

2017 ◽  
Vol 20 (3) ◽  
pp. 420-432 ◽  
Author(s):  
Zorana J Andersen ◽  
Marie Pedersen ◽  
Gudrun Weinmayr ◽  
Massimo Stafoggia ◽  
Claudia Galassi ◽  
...  
Keyword(s):  
Air Pollution ◽  
Brain Tumor ◽  
Ambient Air ◽  
Ambient Air Pollution ◽  
European Study ◽  
Pollution Effects ◽  
Air Pollution Effects

Long-Term Exposure to Ambient Air Pollution and Myocardial Infarction-A systematic review and meta-analysis

2020 ◽  
Author(s):  
Wenning Fu ◽  
Li Zou ◽  
Hongbin Xu ◽  
Xiantao Zeng ◽  
Shijiao Yan ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Systematic Review ◽  
Air Pollution ◽  
Cohort Studies ◽  
Meta Analysis ◽  
Ambient Air ◽  
Ambient Air Pollution ◽  
Pm 2.5 ◽  
Pm 10

Abstract Background and Objective: An increasing amount of epidemiological original studies suggested that long-term exposure to particulate matter (PM 2.5 and PM 10 ) could be associated with the risk of myocardial infarction(MI), but the results were inconsistent. We aimed to synthesized available cohort studies to identify the association between ambient air pollution (PM 2.5 and PM 10 ) and MI risk by a meta-analysis. Methods: PubMed and Embase were searched through September 2019 to identify studies that met predetermined inclusion criterion. Reference lists from retrieved articles were also reviewed. A random-effects model was used to calculate the pooled relative risk ( RR ) and 95% confidence intervals ( CI ). Results: Twenty-two cohort studies involving 6,567,314 participants and 865,98 patients with MI were included in this systematic review. The pooled results showed that higher levels of ambient air pollution (PM 2.5 and PM 10 ) exposure were significantly associated with the risk of MI. The pooled relative ratio ( RR) for each 10-μg/m 3 increment in PM 2.5 and PM 10 were 1.20 (95% CI : 1.11–1.29), and1.03 (95% CI :1.00-1.07) respectively. Exclusion of any single study did not materially alter the combined risk estimate. Conclusions: Integrated evidence from cohort studies supports the hypothesis that long-term exposure to PM 2.5 and PM 10 as a risk factor for MI.

Long-term Exposure to Ambient Air Pollution and Incidence of Brain Tumor in 12 European Cohorts: the European Study of Cohorts for Air Pollution Effects (ESCAPE)

2016 ◽  
Vol 2016 (1) ◽  
Author(s):  
Zorana Jovanovic Andersen* ◽  
Marie Pedersen ◽  
Gudrun Weinmayr ◽  
Claudia Galassi ◽  
Massimo Stafoggia ◽  
...  
Keyword(s):  
Air Pollution ◽  
Brain Tumor ◽  
Ambient Air ◽  
Ambient Air Pollution ◽  
European Study ◽  
Pollution Effects ◽  
Air Pollution Effects
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