Snus in pregnancy and infant birth size: a mother–child birth cohort study

RationaleWhile recent studies show that maternal use of snus during pregnancy is increasing, the potential effects on infant birth size is less investigated, with conflicting results.ObjectivesWe aimed to determine if maternal use of snus during pregnancy influences the infant anthropometric and proportional size measures at birth.MethodsIn 2313 mother–child pairs from the population-based, mother–child birth cohort PreventADALL (Preventing Atopic Dermatitis and ALLergies) in Norway and Sweden, we assessed nicotine exposure by electronic questionnaire(s) at 18 and 34 weeks of pregnancy, and anthropometric measurements at birth. Associations between snus exposure and birth size outcomes were analysed by general linear regression.ResultsBirthweight was not significantly different in infants exposed to snus in general, and up to 18 weeks of pregnancy in particular, when adjusting for relevant confounders including maternal age, gestational age at birth, pre-pregnancy body mass index, parity, fetal sex and maternal gestational weight gain up to 18 weeks. We found no significant effect of snus use on the other anthropometric or proportional size measures in multivariable linear regression models. Most women stopped snus use in early pregnancy.ConclusionExposure to snus use in early pregnancy, with most women stopping when knowing about their pregnancy, was not associated with birth size. We were unable to conclude on effects of continued snus use during pregnancy because of lack of exposure in our cohort.

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Maternal diabetes in early pregnancy, and psychotic experiences and depressive symptoms in 10-year-old offspring: A population-based birth cohort study

Schizophrenia Research ◽

10.1016/j.schres.2018.12.016 ◽

2019 ◽

Vol 206 ◽

pp. 52-57 ◽

Cited By ~ 3

Author(s):

Syudo Yamasaki ◽

Shuntaro Ando ◽

Marcus Richards ◽

Stephani L. Hatch ◽

Shinsuke Koike ◽

...

Keyword(s):

Cohort Study ◽

Depressive Symptoms ◽

Birth Cohort ◽

Early Pregnancy ◽

Maternal Diabetes ◽

Population Based ◽

Birth Cohort Study ◽

Psychotic Experiences

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The Shared Pleasure Paradigm: A study in an observational birth cohort in South Africa

Archives of Women s Mental Health ◽

10.1007/s00737-021-01199-0 ◽

2022 ◽

Author(s):

Anusha Lachman ◽

Esme R. Jordaan ◽

Micky Stern ◽

Kirsten A. Donald ◽

Nadia Hoffman ◽

...

Keyword(s):

South Africa ◽

Child Health ◽

Birth Cohort ◽

Infant Development ◽

Infant Health ◽

Health Study ◽

Birth Cohort Study ◽

Linear Regression Models ◽

Middle Income ◽

Infant Birth

AbstractMother–infant dyads in low- and middle-income countries (LMICs) may be exposed to a range of factors associated with suboptimal development. Optimal infant development is likely supported by synchronicity in the early mother–infant relationship, but limited corroborative research is available in LMICs. The Drakenstein Child Health Study (DCHS) provided an opportunity to study this synchronicity and its associations in South Africa. A South African birth cohort study investigating early-life determinants of child health in a LMIC context provided participants. The Shared Pleasure (SP) paradigm helped assess early mother–infant synchronicity in videos of a sub-set of 291 mother–infant dyads at their 14-week well baby visit. General linear regression models investigated the relationship between selected maternal and infant characteristics and the presence of Shared Pleasure moments. Out of a possible 291 dyads, 82% (n = 239) yielded Shared Pleasure moments. The mean age of mothers was 27 years, while infant sex distribution comprised 54% females and 46% males. The shortest single Shared Pleasure moment lasted at least 0.5 s and the longest 28 s. Shared Pleasure moments were associated with higher gestation age at delivery (p = 0.008) and higher infant birth weight (p = 0.006), but were not related to mother's mental health and infant health outcomes at 14 weeks. The high frequency of positive Shared Pleasure moments in reciprocal dyadic interactions in this sample suggests that significant disruption in shared pleasure may be present only in extreme cases (e.g. mothers with severe mental disorders). Further work is needed to investigate the mechanisms underlying the associations between early mother–infant synchronicity and better outcomes noted here, and to assess whether SP may serve as a culturally appropriate screen for assessing connectedness.

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