scholarly journals The Shared Pleasure Paradigm: A study in an observational birth cohort in South Africa

2022 ◽  
Author(s):  
Anusha Lachman ◽  
Esme R. Jordaan ◽  
Micky Stern ◽  
Kirsten A. Donald ◽  
Nadia Hoffman ◽  
...  
Keyword(s):  
South Africa ◽  
Child Health ◽  
Birth Cohort ◽  
Infant Development ◽  
Infant Health ◽  
Health Study ◽  
Birth Cohort Study ◽  
Linear Regression Models ◽  
Middle Income ◽  
Infant Birth

AbstractMother–infant dyads in low- and middle-income countries (LMICs) may be exposed to a range of factors associated with suboptimal development. Optimal infant development is likely supported by synchronicity in the early mother–infant relationship, but limited corroborative research is available in LMICs. The Drakenstein Child Health Study (DCHS) provided an opportunity to study this synchronicity and its associations in South Africa. A South African birth cohort study investigating early-life determinants of child health in a LMIC context provided participants. The Shared Pleasure (SP) paradigm helped assess early mother–infant synchronicity in videos of a sub-set of 291 mother–infant dyads at their 14-week well baby visit. General linear regression models investigated the relationship between selected maternal and infant characteristics and the presence of Shared Pleasure moments. Out of a possible 291 dyads, 82% (n = 239) yielded Shared Pleasure moments. The mean age of mothers was 27 years, while infant sex distribution comprised 54% females and 46% males. The shortest single Shared Pleasure moment lasted at least 0.5 s and the longest 28 s. Shared Pleasure moments were associated with higher gestation age at delivery (p = 0.008) and higher infant birth weight (p = 0.006), but were not related to mother's mental health and infant health outcomes at 14 weeks. The high frequency of positive Shared Pleasure moments in reciprocal dyadic interactions in this sample suggests that significant disruption in shared pleasure may be present only in extreme cases (e.g. mothers with severe mental disorders). Further work is needed to investigate the mechanisms underlying the associations between early mother–infant synchronicity and better outcomes noted here, and to assess whether SP may serve as a culturally appropriate screen for assessing connectedness.

scholarly journals Prevalence and Correlates of Vitamin D Deficiency among Young South African Infants: A Birth Cohort Study

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1500
Author(s):  
Jabulani R. Ncayiyana ◽  
Leonardo Martinez ◽  
Elizabeth Goddard ◽  
Landon Myer ◽  
Heather J. Zar
Keyword(s):  
Vitamin D ◽  
Child Health ◽  
Vitamin D Deficiency ◽  
Birth Cohort ◽  
Early Life ◽  
Vitamin D Supplementation ◽  
Sub Saharan Africa ◽  
Health Study ◽  
Birth Cohort Study ◽  
Young Infants

Early-life vitamin D deficiency is associated with adverse child health outcomes, but the prevalence of vitamin D deficiency and its correlates in infants remains underexplored, particularly in sub-Saharan Africa. We aimed to investigate the prevalence of vitamin D deficiency and its correlates among young infants in South Africa. This study included 744 infants, aged 6–10 weeks from the Drakenstein Child Health Study, a population-based birth cohort. Infants were categorized into distinct categories based on serum 25(OH)D concentration level including deficient (<50 nmol/L), insufficient (50–74 nmol/L), and sufficient (≥75 nmol/L). Using multivariable Tobit and logistic regression models, we examined the correlates of serum 25(OH)D3 levels. The overall prevalence of vitamin D deficiency was 81% (95% confidence intervals (CI]) 78–83). Multivariable regression analysis showed that serum 25(OH)D3 concentration was independently associated with study site, socioeconomic status, and sex. Birth in winter and breastfeeding were the strongest predictors of lower serum 25(OH)D3 concentration levels. Compared to non-breastfed children, children breastfed were at higher risk of vitamin D deficiency (AOR, 1.96; 95% CI, 1.04–3.67) and breastfeeding for more than one month was associated with greater likelihood of vitamin D deficiency (AOR, 5.40; 95% CI, 2.37–12.32) and lower vitamin D concentrations (−16.22 nmol/L; 95% CI, −21.06, −11.39). Vitamin D deficiency in infants is ubiquitous, under-recognised, and strongly associated with season of birth and breastfeeding in this setting. Nutritional interventions with vitamin D supplementation in national health programs in low- and middle-income countries are urgently needed to improve early-life vitamin D status in infants.

scholarly journals Snus in pregnancy and infant birth size: a mother–child birth cohort study

2019 ◽  
Vol 5 (4) ◽  
pp. 00255-2019
Author(s):  
Ina Kreyberg ◽  
Katarina Hilde ◽  
Karen Eline S. Bains ◽  
Kai-Håkon Carlsen ◽  
Berit Granum ◽  
...  
Keyword(s):  
Linear Regression ◽  
Birth Cohort ◽  
Early Pregnancy ◽  
Population Based ◽  
Birth Cohort Study ◽  
Birth Size ◽  
Linear Regression Models ◽  
Child Birth ◽  
Gestational Age At Birth ◽  
Infant Birth

RationaleWhile recent studies show that maternal use of snus during pregnancy is increasing, the potential effects on infant birth size is less investigated, with conflicting results.ObjectivesWe aimed to determine if maternal use of snus during pregnancy influences the infant anthropometric and proportional size measures at birth.MethodsIn 2313 mother–child pairs from the population-based, mother–child birth cohort PreventADALL (Preventing Atopic Dermatitis and ALLergies) in Norway and Sweden, we assessed nicotine exposure by electronic questionnaire(s) at 18 and 34 weeks of pregnancy, and anthropometric measurements at birth. Associations between snus exposure and birth size outcomes were analysed by general linear regression.ResultsBirthweight was not significantly different in infants exposed to snus in general, and up to 18 weeks of pregnancy in particular, when adjusting for relevant confounders including maternal age, gestational age at birth, pre-pregnancy body mass index, parity, fetal sex and maternal gestational weight gain up to 18 weeks. We found no significant effect of snus use on the other anthropometric or proportional size measures in multivariable linear regression models. Most women stopped snus use in early pregnancy.ConclusionExposure to snus use in early pregnancy, with most women stopping when knowing about their pregnancy, was not associated with birth size. We were unable to conclude on effects of continued snus use during pregnancy because of lack of exposure in our cohort.

Birth to ten: child health in South Africa in the 1990s. Rationale and methods of a birth cohort study

1991 ◽  
Vol 5 (2) ◽  
pp. 211-233 ◽  
Author(s):  
D. Yach ◽  
N. Cameron ◽  
N. Padayachee ◽  
L. Wagstaff ◽  
L. Richter ◽  
...  
Keyword(s):  
South Africa ◽  
Cohort Study ◽  
Child Health ◽  
Birth Cohort ◽  
Birth Cohort Study

Birth to ten: child health in South Africa in the 1990s. Rationale and methods of a birth cohort study

1992 ◽  
Vol 5 (2) ◽  
pp. 211-233
Author(s):  
D. Yach ◽  
N. Cameron ◽  
N. Padayachee ◽  
L. Wagstaff ◽  
L. Richter ◽  
...  
Keyword(s):  
South Africa ◽  
Cohort Study ◽  
Child Health ◽  
Birth Cohort ◽  
Birth Cohort Study

scholarly journals Free and Total Amino Acids in Human Milk in Relation to Maternal and Infant Characteristics and Infant Health Outcomes: The Ulm SPATZ Health Study

Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 2009
Author(s):  
Joris H.J. van Sadelhoff ◽  
Linda P. Siziba ◽  
Lisa Buchenauer ◽  
Marko Mank ◽  
Selma P. Wiertsema ◽  
...  
Keyword(s):  
Amino Acids ◽  
Health Outcomes ◽  
Human Milk ◽  
Infant Development ◽  
Infant Health ◽  
Child Growth ◽  
Health Study ◽  
Maternal Characteristics ◽  
Tract Infections ◽  
Total Amino Acids

Free amino acids (FAAs) are important regulators of key pathways necessary for growth, development, and immunity. Data on FAAs in human milk (HM) and their roles in infant development are limited. We investigated the levels of FAAs and total amino acids (TAA, i.e., the sum of conjugated amino acids and FAAs) in HM in relation to infant and maternal characteristics and immunological conditions. FAA and TAA levels in HM sampled at 6 weeks (n = 671) and 6 months (n = 441) of lactation were determined using high-performance liquid chromatography. Child growth was ascertained at 4–5 weeks and at 6–7 months of age. Child allergy and lower respiratory tract infections were assessed in the first years of life. Associations of amino acid (AA) levels in HM with child growth and health outcomes were determined by Spearman correlation and modified Poisson regression, respectively. Free glutamine, glutamate, and serine in 6-week HM positively correlated with infant weight gain in the first 4–5 weeks of age. Maternal pre-pregnancy weight and body mass index (BMI) were negatively correlated with free glutamine and asparagine in 6-week and 6-month HM and positively correlated with the sum of TAAs in 6-month HM, but significance was lost following confounder adjustment. Free glutamine was lower in 6-month HM of mothers with an allergy (either active or non-active). No consistent associations were found between FAAs in HM and child health outcomes. However, potential negative associations were observed between specific FAAs and the risk of food allergy. These results suggest that specific FAAs play a role in infant growth. Moreover, these findings warrant further investigations into the relation of FAAs in HM with infant health outcomes and maternal allergy.

scholarly journals Association between In Utero arsenic exposure, placental gene expression, and infant birth weight: a US birth cohort study

2013 ◽  
Vol 12 (1) ◽  
Author(s):  
Dennis Liang Fei ◽  
Devin C Koestler ◽  
Zhigang Li ◽  
Camilla Giambelli ◽  
Avencia Sanchez-Mejias ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cohort Study ◽  
Birth Weight ◽  
Birth Cohort ◽  
Arsenic Exposure ◽  
In Utero ◽  
Birth Cohort Study ◽  
Infant Birth

scholarly journals Delirium symptoms are associated with decline in cognitive function between ages 53 to 69: findings from a British birth cohort study

2017 ◽  
Author(s):  
A Tsui ◽  
D Kuh ◽  
M Richards ◽  
D Davis
Keyword(s):  
Birth Cohort ◽  
Verbal Memory ◽  
Regression Models ◽  
Cognitive Outcomes ◽  
Birth Cohort Study ◽  
Linear Regression Models ◽  
Cognitive Domains ◽  
Time Period ◽  
Search Speed ◽  
Addenbrooke’S Cognitive Examination

AbstractINTRODUCTIONFew population studies have investigated whether longitudinal decline after delirium in mid-to-late life might affect specific cognitive domains.METHODSParticipants from a birth cohort completing assessments of search speed, verbal memory and the Addenbrooke’s Cognitive Examination at age 69 were asked about delirium symptoms between ages 60-69. Linear regression models estimated associations between delirium symptoms and cognitive outcomes.RESULTSPeriod prevalence of delirium between 60 and 69 was 4% (95% CI 3.2%,4.9%). Self-reported symptoms of delirium over the seventh decade were associated with worse scores in the Addenbrooke’s Cognitive Examination (−1.7 points, 95% CI −3.2, −0.1, p=0.04). In association with delirium symptoms, verbal memory scores were initially lower, with subsequent decline in search speed by age 69. These effects were independent of other Alzheimer’s risk factors.DISCUSSIONDelirium symptoms may be common even at relatively younger ages, and their presence may herald cognitive decline, particularly in search speed, over this time period.

scholarly journals An association between maternal weight change in the year before pregnancy and infant birth weight: ELFE, a French national birth cohort study

PLoS Medicine ◽  
2019 ◽  
Vol 16 (8) ◽  
pp. e1002871 ◽  
Author(s):  
Marion Lecorguillé ◽  
Madalina Jacota ◽  
Blandine de Lauzon-Guillain ◽  
Anne Forhan ◽  
Marie Cheminat ◽  
...  
Keyword(s):  
Cohort Study ◽  
Birth Weight ◽  
Birth Cohort ◽  
Weight Change ◽  
Birth Cohort Study ◽  
Maternal Weight ◽  
Infant Birth

scholarly journals Cohort profile: the Maternal and Child Health and Nutrition in Acre, Brazil, birth cohort study (MINA-Brazil)

BMJ Open ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. e034513
Author(s):  
Marly A Cardoso ◽  
Alicia Matijasevich ◽  
Maira Barreto Malta ◽  
Barbara Hatzlhoffer Lourenco ◽  
Suely G A Gimeno ◽  
...  
Keyword(s):  
Child Health ◽  
Birth Cohort ◽  
Maternal And Child Health ◽  
Retention Rate ◽  
Epidemiological Data ◽  
Childhood Development ◽  
Birth Cohort Study ◽  
Health And Nutrition ◽  
And Child Health

PurposeMaternal and Child Health and Nutrition in Acre, Brazil (MINA-Brazil) is a longitudinal, prospective population-based birth cohort, set-up to understand the effects of early environmental exposures and maternal lifestyle choices on growth and development of the Amazonian children.ParticipantsMother–baby pairs (n=1246) were enrolled at delivery from July 2015 to June 2016 in Cruzeiro do Sul, Acre, Brazil. Mothers of 43.7% of the cohort were recruited in the study during pregnancy from February 2015 to January 2016. Study visits took place during pregnancy, delivery, at 1 month, 6 months, 1 year and 2 years after delivery. In addition to clinical and epidemiological data, samples collected by the MINA-Brazil study include plasma, serum and extracted DNA from blood and faeces, which are stored in a biobank.Findings to dateKey baseline reports found a high prevalence of gestational night blindness (11.5%; 95% CI 9.97% to 13.25%) and maternal anaemia (39.4%; 95% CI 36.84% to 41.95%) at delivery. Antenatal malaria episodes (74.6% ofPlasmodium vivax) were diagnosed in 8.0% of the women and were associated with an average reduction in birth weight z-scores of 0.35 (95% CI 0.14 to 0.57) and in birth length z-scores of 0.31 (95% CI 0.08 to 0.54), compared with malaria-free pregnancies. At 2-year follow-up, data collection strategies combined telephone calls, WhatsApp, social media community and home visits to minimise losses of follow-up (retention rate of 79.5%).Future plansA 5-year follow-up visit is planned in 2021 with similar interviews and biospecimens collection. The findings from this prospective cohort will provide novel insights into the roles of prenatal and postnatal factors in determining early childhood development in an Amazonian population.

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