scholarly journals Tiotropium might improve survival in subjects with COPD at high risk of mortality

2014 ◽  
Vol 15 (1) ◽  
pp. 64 ◽  
Author(s):  
Pierre-Régis Burgel ◽  
Jean-Louis Paillasseur ◽  
Daniel Dusser ◽  
Nicolas Roche ◽  
Dacheng Liu ◽  
...  
Keyword(s):  
High Risk ◽  
Risk Of Mortality

scholarly journals Fecal impaction and colon obstruction

2021 ◽  
Vol 8 (3) ◽  
pp. 988
Author(s):  
Haitham A. Saimeh
Keyword(s):  
Gastrointestinal Tract ◽  
High Risk ◽  
Dietary Fiber ◽  
Water Intake ◽  
Early Recognition ◽  
Fecal Impaction ◽  
Lower Gastrointestinal Tract ◽  
Mortality And Morbidity ◽  
Risk Of Mortality ◽  
Lethal Complications

Fecal impaction is an important cause of lower gastrointestinal tract obstruction and carries high risk of mortality and morbidity, it is highly emphasized to early identify it to minimize any risk of complication. Recurrence is common, therefore preventive modalities as increasing the dietary fiber content to 30 gm/day, water intake, or discontinuation of medications that contribute to colon hypomotility. In this paper, I am pointing off the early recognition and treatment of fecal impaction to avoid lethal complications, therefore physicians should have higher level of suspicions because if fecal impaction goes unrecognized this will lead to fatal morbidity and mortality.

scholarly journals Inguinal abscess in twin infants

2020 ◽  
Vol 7 (5) ◽  
pp. 1704
Author(s):  
Meghmala Sadhukhan ◽  
Baikuntha N. Mishra ◽  
Ranjit K. Joshi ◽  
Prabin Prakash Pahi
Keyword(s):  
Immune System ◽  
High Risk ◽  
Normal Flora ◽  
Delayed Treatment ◽  
Quick Recovery ◽  
Risk Of Mortality ◽  
Haematogenous Spread ◽  
Groin Swelling ◽  
Immature Immune System ◽  
In Infants And Children

Inguinal abscess is uncommon in infants and children. Majority of cases in the infantile period is primary and they present as leg or groin swelling, limitation of limb movement and pain. The source of microorganism is from the haematogenous spread of normal flora of the skin due to immature immune system. Ultrasound is the investigation of choice which confirms the diagnosis and delineates the areas of collection. Antibiotic alone is insufficient in most cases and drainage is required. Delayed treatment and inadequate drainage carry a high risk of mortality and sequelae due to damage to the underlying joint. We present 2 cases of primary inguinal abscess in twin infants who presented at 1 month and 2 months of age correspondingly, in whom early diagnosis and management lead to quick recovery.

scholarly journals OUTCOMES IN THE COREVALVE US HIGH-RISK PIVOTAL TRIAL IN PATIENTS WITH A SOCIETY OF THORACIC SURGEONS PREDICTED RISK OF MORTALITY LESS THAN OR EQUAL TO 7

2016 ◽  
Vol 67 (13) ◽  
pp. 121
Author(s):  
Michael J. Reardon ◽  
David Adams ◽  
Neal Kleiman ◽  
G. Michael Deeb ◽  
Steven Yakubov ◽  
...  
Keyword(s):  
High Risk ◽  
Pivotal Trial ◽  
Risk Of Mortality ◽  
Predicted Risk

Percutaneous device closure of a large complex aortic root pseudoaneurysm

2020 ◽  
Vol 13 (9) ◽  
pp. e235545
Author(s):  
Patrick Tran ◽  
Jamal Nasir Khan ◽  
David Hildick-Smith ◽  
Martin Been
Keyword(s):  
High Risk ◽  
Aortic Valve ◽  
Significant Risk ◽  
Unique Case ◽  
Risk Of Mortality ◽  
Percutaneous Device ◽  
Procedural Complication ◽  
Endovascular Approach ◽  
A Minor ◽  
Percutaneous Device Closure

Pseudoaneurysm of the aorta is a rare and high-risk complication of native aortic valve endocarditis and can develop following cardiac surgery for aortic valve and root disease. If left untreated, there is a significant risk of aortic wall rupture and fatality. Given the high risk of mortality associated with traditional open surgical repair of aortic pseudoaneurysms, endovascular approach is a potentially favourable alternative. We describe a unique case of a young woman with a large and complex paraprosthetic pseudoaneurysm with multiple communicating fistulae which was successfully percutaneously treated with two occluder devices. In this technically challenging case, a minor but unique procedural complication is also illustrated.

Identifying Older Adults at High Risk of Mortality Using the Medicare Health Outcomes Survey

2012 ◽  
Vol 35 (4) ◽  
pp. 277-291 ◽  
Author(s):  
Judy H. Ng ◽  
Marc N. Elliott ◽  
Sarah Hudson Scholle ◽  
Kazi Ahmed ◽  
Rachel L. Collins ◽  
...  
Keyword(s):  
Older Adults ◽  
High Risk ◽  
Health Outcomes ◽  
Risk Of Mortality

The effect of gaps in chemotherapy on survival in patients with high-risk stage II and stage III colon cancer.

2012 ◽  
Vol 30 (34_suppl) ◽  
pp. 180-180
Author(s):  
Yvonne Sada ◽  
Zhigang Duan ◽  
Hashem El-Serag ◽  
Jessica Davila
Keyword(s):  
Colon Cancer ◽  
High Risk ◽  
Stage Ii ◽  
Stage Iii ◽  
Clinical Factors ◽  
Stage Iii Colon Cancer ◽  
Risk Of Mortality ◽  
Increased Risk ◽  
Multivariable Regression ◽  
The Impact

180 Background: Current guidelines recommend six months of chemotherapy (CT) for stage III colon cancer and consideration for high-risk stage II colon cancer. No previous studies have examined the impact of CT gaps on survival. This retrospective study examines determinants of CT gaps and the effect of gaps on survival. Methods: Using national Surveillance, Epidemiology, and End Results registry-Medicare linked data, high-risk stage II and stage III colon cancer patients diagnosed between 2000-2007 who received surgery and CT were identified. CT duration and gaps were calculated. CT gap was defined as 30 to 90 days between two CT claims. Data on demographics, clinical factors (comorbidity, tumor grade), and treatment factors (time to CT initiation, toxicity, hospitalization) were collected. Multivariable regression was used to examine factors associated with gaps. Cox proportional hazards analysis examined the effect of gaps on risk of mortality. Results: 7,371 patients were identified. Median age was 75 (IQR: 71-79); 47% were male. Among all patients, 1,803 (24%) had a gap. 2,674 patients (36%) received 5 to 7 months of CT, of which 469 (18%) had a gap. Multivariable regression analysis showed that patients who were black (OR 1.3, 95% CI: 1.1-1.7), stage III (1.2, 1.0-1.3), had toxicity (1.3, 1.1-1.4), or had 3 to 4 months of CT (vs. 5-7 months, 2.6, 2.3-3.0) were more likely to have a gap, while patients with a more recent diagnosis in 2007(vs. 2000, 0.6, 0.5-0.8) were less likely to have a gap. 3-year cancer-specific survival was the same in all patients with CT gaps compared with no gaps (80%, 95% CI: 78%-82% vs. 81%, 95% CI: 80%-82%). Cox proportional hazard models showed that patients with gaps did not have increased risk of mortality (HR 0.99, 0.89-1.1) adjusting for patient and clinical factors. Among those who received 5 to 7 months of CT, 3-year survival was 8% lower in patients with gaps compared to those with no gaps (80%, 95% CI: 75%-83% vs. 88%, 95% CI: 87%-90%). Conclusions: Nearly 25% of high-risk stage II and III patients who received CT had a gap. CT gaps were associated with worse survival in patients who received 5 to 7 months of CT. Interventions to improve CT toxicity management and reduce gaps are needed to maximize the benefit of CT.

Institution-Wide QT Alert System Identifies Patients With a High Risk of Mortality

2013 ◽  
Vol 88 (4) ◽  
pp. 315-325 ◽  
Author(s):  
Kristina H. Haugaa ◽  
J. Martijn Bos ◽  
Robert F. Tarrell ◽  
Bruce W. Morlan ◽  
Pedro J. Caraballo ◽  
...  
Keyword(s):  
High Risk ◽  
Alert System ◽  
Risk Of Mortality
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