scholarly journals Gene expression patterns that predict sensitivity to epidermal growth factor receptor tyrosine kinase inhibitors in lung cancer cell lines and human lung tumors

BMC Genomics ◽  
2006 ◽  
Vol 7 (1) ◽  
Author(s):  
Justin M Balko ◽  
Anil Potti ◽  
Christopher Saunders ◽  
Arnold Stromberg ◽  
Eric B Haura ◽  
...  
Keyword(s):  
Gene Expression ◽  
Receptor Tyrosine Kinase ◽  
Kinase Inhibitors ◽  
Human Lung ◽  
Expression Patterns ◽  
Growth Factor Receptor ◽  
Gene Expression Patterns ◽  
Lung Cancer Cell ◽  
Epidermal Growth ◽  
Receptor Tyrosine Kinase Inhibitors

Chitosan-derived Nanoparticles Impede Signal Transduction for T790M Lung Cancer Therapy

2021 ◽  
Author(s):  
Guojun Huang ◽  
Qi Chen ◽  
Jiawei Hu ◽  
Jianming Mao ◽  
Yunhong He ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Receptor Tyrosine Kinase ◽  
Kinase Inhibitors ◽  
Growth Factor Receptor ◽  
T790m Mutation ◽  
Develop Disease Progression ◽  
Lung Cancer Therapy ◽  
Epidermal Growth ◽  
Egfr Tkis ◽  
Receptor Tyrosine Kinase Inhibitors

Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) treated patients ultimately develop disease progression, about 50% of which involved in the emergence of a T790M mutation acquiring drug resistance. In...

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