scholarly journals Environmental exposures and their genetic or environmental contribution to depression and fatigue: a twin study in Sri Lanka

2010 ◽  
Vol 10 (1) ◽  
Author(s):  
Harriet A Ball ◽  
Sisira H Siribaddana ◽  
Athula Sumathipala ◽  
Yulia Kovas ◽  
Nick Glozier ◽  
...  
2012 ◽  
Vol 83 (10) ◽  
pp. e1.10-e1
Author(s):  
H Ball ◽  
R Dutta ◽  
A Sumathipala ◽  
S Siribaddana ◽  
M Hotopf ◽  
...  

2008 ◽  
Vol 8 (1) ◽  
Author(s):  
Sisira H Siribaddana ◽  
Harriet A Ball ◽  
Suwin N Hewage ◽  
Nick Glozier ◽  
Yulia Kovas ◽  
...  

2009 ◽  
Vol 195 (6) ◽  
pp. 504-509 ◽  
Author(s):  
Harriet A. Ball ◽  
Athula Sumathipala ◽  
Sisira H. Siribaddana ◽  
Yulia Kovas ◽  
Nick Glozier ◽  
...  

BackgroundSusceptibility to depression results from genetic and non-familially shared environmental influences in high-income, Western countries. Environments may play a different role for populations in different contexts.AimsTo examine heritability of depression in the first large, population-based twin study in a low-income country.MethodLifetime depression and a broader measure of depression susceptibility (D-probe) were assessed in 3908 adult twins in Sri Lanka (the CoTASS study).ResultsThere were gender differences for the broad definition (D-probe), with a higher genetic contribution in females (61%) than males (4%). Results were similar for depression, but the prevalence was too low to estimate heritability for males.ConclusionsGenetic influences on depression in women appear to be at least as strong in this Sri Lankan sample as in higher-income countries. Conclusions are less clear for men but suggest a larger role for environments rather than genes. The nature as well as the magnitude of environmental influences may also differ across populations.


2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Kaushalya Jayaweera ◽  
Lisa Aschan ◽  
Gayani Pannala ◽  
Anushka Adikari ◽  
Nicholas Glozier ◽  
...  

2006 ◽  
Vol 9 (6) ◽  
pp. 808-810 ◽  
Author(s):  
Kazuo Hayakawa ◽  
Kenji Kato ◽  
Miyuki Onoi ◽  
Cai Yang-Ping ◽  
Masao Kanamori ◽  
...  

AbstractThe Osaka University Aged Twin Registry (OUATR) is the largest adult twin registry in Japan. Since its establishment in 1974, the OUATR has conducted a number of studies with particular focus on the environmental contribution to physical–cognitive–mental aging, longevity and aging-dependent diseases in later adulthood. The registry consists of 12,000 pairs of Japanese twins born between 1900 and 1935. Two hundred and fifty pairs of twins have undergone comprehensive medical examination to date. Follow-up questionnaires have been mailed out on a regular basis, for the purpose of checking current vital statuses, health conditions, and so forth. The main objective of this longitudinal twin study is to contribute to the prevention of lifestyle-related diseases and the promotion of successful aging.


2015 ◽  
Vol 21 ◽  
pp. 114-115
Author(s):  
Kavinga Gunawardane ◽  
Noel Somasundaram ◽  
Neil Thalagala ◽  
Pubudu Chulasiri ◽  
Sudath Fernando

Crisis ◽  
2010 ◽  
Vol 31 (1) ◽  
pp. 30-35 ◽  
Author(s):  
Sudath Samaraweera ◽  
Athula Sumathipala ◽  
Sisira Siribaddana ◽  
S. Sivayogan ◽  
Dinesh Bhugra

Background: Suicidal ideation can often lead to suicide attempts and completed suicide. Studies have shown that Sri Lanka has one of the highest rates of suicide in the world but so far no studies have looked at prevalence of suicidal ideation in a general population in Sri Lanka. Aims: We wanted to determine the prevalence of suicidal ideation by randomly selecting six Divisional Secretariats (Dss) out of 17 in one district. This district is known to have higher than national average rates of suicide. Methods: 808 participants were interviewed using Sinhala versions of GHQ-30 and Beck’s Scale for Suicidal Ideation. Of these, 387 (48%) were males, and 421 (52%) were female. Results: On Beck’s Scale for Suicidal Ideation, 29 individuals (4%) had active suicidal ideation and 23 (3%) had passive suicidal ideation. The active suicidal ideators were young, physically ill and had higher levels of helplessness and hopelessness. Conclusions: The prevalence of suicidal ideation in Sri Lanka is lower than reported from the West and yet suicide rates are higher. Further work must explore cultural and religious factors.


Crisis ◽  
2002 ◽  
Vol 23 (3) ◽  
pp. 104-107 ◽  
Author(s):  
Murad M. Khan

Summary: The Indian subcontinent comprises eight countries (India, Pakistan, Bangladesh, Nepal, Sri Lanka, Afghanistan, Bhutan, and the Maldives) and a collective population of more than 1.3 billion people. 10% of the world's suicides (more than 100,000 people) take place in just three of these countries, viz. India, Sri Lanka, and Pakistan. There is very little information on suicides from the other four countries. Some differences from suicides in Western countries include the high use of organophosphate insecticides, larger numbers of married women, fewer elderly subjects, and interpersonal relationship problems and life events as important causative factors. There is need for more and better information regarding suicide in the countries of the Indian subcontinent. In particular, studies must address culture-specific risk factors associated with suicide in these countries. The prevention of this important public health problem in an area of the world with myriad socio-economic problems, meager resources, and stigmatization of mental illness poses a formidable challenge to mental health professionals, policy makers, and governments of these countries.


1998 ◽  
Vol 53 (7) ◽  
pp. 771-777 ◽  
Author(s):  
John D. Rogers ◽  
Jonathan Spencer ◽  
Jayadeva Uyangoda

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