scholarly journals Effect of lycopene on cell viability and cell cycle progression in human cancer cell lines

2012 ◽  
Vol 12 (1) ◽  
pp. 36 ◽  
Author(s):  
Anderson Teodoro ◽  
Felipe Oliveira ◽  
Nathalia Martins ◽  
Guilherme de Maia ◽  
Renata Martucci ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cell Viability ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cell Cycle Progression ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Cycle Progression ◽  
Human Cancer Cell Lines

scholarly journals Characterization of 2,3,6,7,10,11-hexahydroxytriphenylene and its effects on cell viability in human cancer cell lines

2016 ◽  
Vol 94 (2) ◽  
pp. 205-211 ◽  
Author(s):  
Karine P. Naidek ◽  
Cristiane R. Zuconelli ◽  
Otavio M. Cruz ◽  
Ronny Ribeiro ◽  
Sheila M.B. Winnischofer ◽  
...  
Keyword(s):  
Cell Viability ◽  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Annexin V ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Paramagnetic Resonance ◽  
Human Cancer Cell Lines

We synthesized 2,3,6,7,10,11-hexahydroxytriphenylene (HHTP), characterized it by electrochemistry, spectroelectrochemistry, and electron paramagnetic resonance techniques, and evaluated its cytotoxicity to human cancer cell lines. The results revealed that HHTP has accessible higher-oxidation states, especially the tris-semiquinone monoradical. This species is stable and is formed after being stored for months. HHTP exhibited cytotoxic effects on 5 human cancer cell lines, including glioma and lung cancer cells. The cytotoxic effect was evaluated based on the decrease in cell viability, increases in the percentage of cells with fragmented DNA, and elevated numbers of annexin V–PI-positive cells after HHTP treatment.

scholarly journals BRG1 mutations found in human cancer cell lines inactivate Rb-mediated cell-cycle arrest

2011 ◽  
Vol 226 (8) ◽  
pp. 1989-1997 ◽  
Author(s):  
Christopher Bartlett ◽  
Tess J. Orvis ◽  
Gary S. Rosson ◽  
Bernard E. Weissman
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines ◽  
Cycle Arrest

scholarly journals INDUCTION OF CELL CYCLE ARREST AND APOPTOSIS BY ORMENIS ERIOLEPIS A MORROCAN ENDEMIC PLANT IN VARIOUS HUMAN CANCER CELL LINES

2017 ◽  
Vol 14 (2) ◽  
pp. 356-373 ◽  
Author(s):  
Lamiae Belayachi ◽  
Clara Aceves-Luquero ◽  
nawel Merghoub ◽  
Silvia Fernandez de Mattos ◽  
Saaid Amzazi ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Endemic Plant ◽  
Human Cancer Cell Lines ◽  
Cycle Arrest

scholarly journals A Warp-Knitted Light-Emitting Fabric-Based Device for In Vitro Photodynamic Therapy: Description, Characterization, and Application on Human Cancer Cell Lines

Cancers ◽  
2021 ◽  
Vol 13 (16) ◽  
pp. 4109
Author(s):  
Elise Thécua ◽  
Laurine Ziane ◽  
Guillaume Paul Grolez ◽  
Alexandre Fagart ◽  
Abhishek Kumar ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cell Viability ◽  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Light Emitting ◽  
Human Cancer Cell Lines

Photodynamic therapy (PDT) appears to be a promising strategy in biomedical applications. However, the complexity of its parameters prevents wide acceptance. This work presents and characterizes a novel optical device based on knitted light-emitting fabrics and dedicated to in vitro PDT involving low irradiance over a long illumination period. Technical characterization of this device, called CELL-LEF, is performed. A cytotoxic study of 5-ALA-mediated PDT on human cancer cell lines is provided as a proof of concept. The target of delivering an irradiance of 1 mW/cm2 over 750 cm2 is achieved (mean: 0.99 mW/cm2; standard deviation: 0.13 mW/cm2). The device can maintain a stable temperature with the mean thermal distribution of 35.1 °C (min: 30.7 °C; max: 38.4 °C). In vitro outcomes show that 5-ALA PDT using CELL-LEF consistently and effectively induced a decrease in tumor cell viability: Almost all the HepG2 cells died after 80 min of illumination, while less than 60% of U87 cell viability remained. CELL-LEF is suitable for in vitro PDT involving low irradiance over a long illumination period.

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