scholarly journals Decrease in Shiga toxin expression using a minimal inhibitory concentration of rifampicin followed by bactericidal gentamicin treatment enhances survival of Escherichia coli O157:H7-infected BALB/c mice

2011 ◽  
Vol 10 (1) ◽  
pp. 34 ◽  
Author(s):  
Elias A Rahal ◽  
Natalie Kazzi ◽  
Ahmad Sabra ◽  
Alexander M Abdelnoor ◽  
Ghassan M Matar
Author(s):  
Christina Ahlstrom ◽  
Petra Muellner ◽  
Geraldine Lammers ◽  
Meghan Jones ◽  
Sophie Octavia ◽  
...  

1993 ◽  
Vol 21 (2) ◽  
pp. 151-155
Author(s):  
Gustaw Kerszman

The toxicity of the first ten MEIC chemicals to Escherichia coli and Bacillus subtilis was examined. Nine of the chemicals were toxic to the bacteria, with the minimal inhibitory concentration (MIC) ranging from 10-3 to 4.4M. The sensitivities of both organisms were similar, but the effect on E. coli was often bactericidal, while it was bacteriostatic for B. subtilis. Digoxin was not detectably toxic to either bacterial species. Amitriptyline and FeSO4 were relatively less toxic to the bacteria than to human cells. For seven chemicals, a highly significant linear regression was established between log MIC in bacteria and log of blood concentration, giving lethal and moderate/mild toxicity in humans, as well as with toxicity to human lymphocytes.


2018 ◽  
Vol 9 ◽  
Author(s):  
Audrey Segura ◽  
Pauline Auffret ◽  
Delphine Bibbal ◽  
Marine Bertoni ◽  
Alexandra Durand ◽  
...  

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