scholarly journals Effects of a commercial product containing guaraná on psychological well-being, anxiety and mood: a single-blind, placebo-controlled study in healthy subjects

2013 ◽  
Vol 12 (1) ◽  
Author(s):  
Gianluca Ivan Silvestrini ◽  
Franca Marino ◽  
Marco Cosentino
Keyword(s):  
Healthy Subjects ◽  
Well Being ◽  
Commercial Product ◽  
Controlled Study ◽  
Psychological Well Being ◽  
Single Blind

The interaction of GHRH with TRH in acromegaly: a controlled study

1991 ◽  
Vol 125 (4) ◽  
pp. 337-341 ◽  
Author(s):  
Bert-Jan Looij ◽  
Ferdinand Roelfsema ◽  
Marijke Frölich ◽  
Arie C. Nieuwenhuijzen Kruseman
Keyword(s):  
Healthy Subjects ◽  
Bolus Injection ◽  
Controlled Study ◽  
Healthy Individuals ◽  
Tsh Secretion ◽  
Single Blind ◽  
Modest Effect

Abstract. In a single-blind placebo-controlled study, the effect of an iv bolus injection of 100 μg GHRH(1–29)NH2 on the response to 200 μg TRH was assessed in 10 untreated patients with acromegaly to determine whether GHRH interacts with TRH in acromegaly, as previously described in healthy subjects. The combination of GHRH(1–29)NH2 with TRH resulted in a larger increment of peak and of integrated plasma TSH and PRL levels than after TRH alone. GHRH alone had no effect on TSH secretion and only a modest effect on PRL secretion. These findings suggest that in acromegaly, like in healthy individuals, GHRH potentiates the TSH response to TRH and that the effects of GHRH and TRH on PRL secretion are additive.

Psychological well-being in out-patients with eating disorders: A controlled study

2013 ◽  
Vol 47 (3) ◽  
pp. 252-258 ◽  
Author(s):  
Elena Tomba ◽  
Emanuela Offidani ◽  
Lucia Tecuta ◽  
Romana Schumann ◽  
Donatella Ballardini
Keyword(s):  
Eating Disorders ◽  
Well Being ◽  
Controlled Study ◽  
Psychological Well Being

scholarly journals Social Functioning and Psychological Well-Being of 347 Young Adults with Epilepsy Only?Population-Based, Controlled Study from Finland

Epilepsia ◽  
2007 ◽  
Vol 48 (5) ◽  
pp. 907-912 ◽  
Author(s):  
Anne Koponen ◽  
Ullamaija Seppälä ◽  
Kai Eriksson ◽  
Pirkko Nieminen ◽  
Antti Uutela ◽  
...  
Keyword(s):  
Young Adults ◽  
Social Functioning ◽  
Well Being ◽  
Population Based ◽  
Controlled Study ◽  
Psychological Well Being

Psychological well-being and social participation assessment in visually impaired subjects playing Torball: A controlled study

2013 ◽  
Vol 34 (4) ◽  
pp. 1204-1209 ◽  
Author(s):  
A. Di Cagno ◽  
E. Iuliano ◽  
G. Aquino ◽  
G. Fiorilli ◽  
C. Battaglia ◽  
...  
Keyword(s):  
Social Participation ◽  
Visually Impaired ◽  
Well Being ◽  
Controlled Study ◽  
Psychological Well Being

scholarly journals Yoga in correctional settings: A randomized controlled study. Frontiers in Psychiatry. 2017 Oct 16; 8:204

2021 ◽  
Vol 2 (2) ◽  
pp. 69
Author(s):  
Kalyan Maity
Keyword(s):  
Positive Affect ◽  
Prison Population ◽  
Meta Analysis ◽  
Holistic Approach ◽  
Well Being ◽  
Positive Outcome ◽  
Controlled Study ◽  
Psychological Well Being ◽  
Specific Effects ◽  
As Stress

Yoga is a holistic approach and it is quite difficult to understand the specific effects of Yoga for its many aspects such as Asana, Pranayama, Meditation, etc. Inspite of these challenges, scientific study on Yoga has been grown optimally. Several studies have shown the positive outcome of Yoga on various psychological and physiological parameters such as stress, anxiety, depression, memory, aggressiveness, etc. ( , ). Prison population is vulnerable to different psychiatric morbidities and often represent antisocial behavior ( , ). A randomized control trial has shown a significant improvement in perceived stress, positive affect, and psychological distress in prisoners after 10 weeks of Yoga practice ( ). A few meta-analysis has also suggested the positive effect of Yoga and meditation on psychological well-being and behavioral functioning in the prison population. The study has revealed that 10 weeks Yoga was associated with increased positive affect, impulse control, psychological well-being, sleep quality, and decreased aggressiveness, stress, and negative affect.

scholarly journals A Return-to-Work Intervention for Prematurely Retired Depression or Anxiety Disorder Patients

2021 ◽  
Vol 12 ◽  
Author(s):  
Eva Behrens-Wittenberg ◽  
Felix Wedegaertner
Keyword(s):  
Return To Work ◽  
Repeated Measures ◽  
Well Being ◽  
Controlled Study ◽  
Control Group ◽  
Depression And Anxiety ◽  
Psychological Well Being ◽  
Novel Approach ◽  
Work Intervention

Background: Depression and anxiety disorders are the most common cause for premature retirement of people of middle age. These people are expelled from the workforce. The following social disintegration can have an additional detrimental effect on subjects' psychological well-being which further reduces the chance to re-enter the workforce. Depression and anxiety in general need not be regarded as irreversible causes of disability. Therefore, long-term disability should be avoidable in many cases. This two-arm prospective controlled study tests a novel approach for those who have become economically inactive due to their illness with the goal to improve psychological well-being and return to work. Forty-one subjects were followed-up on over a period of 12 months and compared to 41 control cases. ANOVA for repeated measures showed that experimental subjects' psychological well-being and work ability was much better after the intervention than in the control group. These findings show that an individually tailored return-to-work intervention can be a useful therapeutic tool even after retirement.

scholarly journals STIMULATORY EFFECT OF ACUTE SINGLE DOSE OF DRIED WHOLE COFFEE CHERRY POWDER ON NRF2 ACTIVITY IN FRESHLY ISOLATED BLOOD CELLS. A SINGLE-BLIND, PLACEBO CONTROLLED CROSS-OVER PILOT CLINICAL STUDY

2016 ◽  
pp. 1-8
Author(s):  
T. Reyes-Izquierdo ◽  
B. Nemzer ◽  
R. Argumedo ◽  
M. Cervantes ◽  
Z. Pietrzkowski
Keyword(s):  
Single Dose ◽  
Blood Cells ◽  
Healthy Subjects ◽  
Oxidant Stress ◽  
Controlled Study ◽  
Related Factor ◽  
Blood Samples ◽  
Additional Testing ◽  
Pilot Clinical Study ◽  
Single Blind

Abstract: Background: NF-E2-related factor 2 (Nrf2) is a transcription factor that participates in the regulation of antioxidant expression during increased oxidant stress. Several phytochemicals and food products have shown to trigger Nrf2 activity. In this pilot placebo-controlled study the effects of a single dose of dried whole coffee cherry powder (“WCCP”) on Nrf2 levels were tested. Objectives: To characterize a blend of WCCP and evaluate the potential effects on mTOR and Nrf2 in healthy subjects. Design: In this cross over study, subjects were given placebo or a single dose of 1000mg WCCP on day 1 and 2. Blood was collected for four time points. Participants served as their own controls. Setting: After supplementation, blood samples were processed for mTOR and Nrf2 analysis. Blood ATP, glucose and lactate were also measured. Participants: Ten healthy subjects, ages ranging from 22 to 35 years and BMI ranging from 24.1 to 30 kg/m² were selected to participate. Results: One 1000 mg dose of WCCP resulted in an average 44% increase of NRf2 levels 180 minutes after ingestion (p=0.03 ). Phosphorylated mTOR (Ser 2448) was reduced at 180 minutes after supplement; when compared to placebo. Correlation (“Corr”) analyses revealed that increases in Nrf2 appear to be associated with mTOR reduction. Blood glucose and extracellular ATP levels were not changed. Conclusions: WCCP increased Nrf2 3 hours after ingestion. Additional testing is required to verify the potency of WCCP on Nrf2, as well as any potential correlation between mTOR (S2448) reduction and increased levels of Nrf2 after supplementation.

scholarly journals Customized Arch Support Insoles Improve Physical Functional Performance in Children: A Randomized Controlled Study

2021 ◽  
Author(s):  
Ying-Chen Kuo ◽  
Ru-Lan Hsieh ◽  
Wen-Chung Lee
Keyword(s):  
Physical Function ◽  
Effect Size ◽  
Functional Performance ◽  
Well Being ◽  
Controlled Study ◽  
Control Group ◽  
Psychological Well Being ◽  
Randomized Controlled ◽  
Arch Support ◽  
Physical Functional Performance

Abstract The effectiveness of arch-support insoles on children remains controversial. We evaluated the short-term therapeutic effects of arch-support insoles on the physical functional performance, physical function, and psychological well-being of healthy children under the International Classification of Functioning, Disability, and Health (ICF) framework. It was a prospective double-blind randomized controlled study. The participants were randomized into 2 groups, the treatment group (with customized arch-support insoles) and the control group (without insoles) for a 12-week intervention period. The walking speed test, stairs ascent and descent tests, the Five Times Sit-to-Stand test, and the Timed Up and Go test for physical functional performance, and the Pediatric Outcome Data Collection Instrument-Parent (PODCI) and the Child Health Questionnaire-Parent Form (CHQ-PF28) for the physical function and psychological well-being of children were assessed. Forty-five children completed the study. Compared with the control group, after 12 weeks of wearing customized insoles, the treatment group exhibited significant improvement in physical functional performance in terms of fastest walking speed (effect size: .515, P = .046), stairs ascent time (effect size: .658, P = .023), and stairs descent time (effect size: .718, P = .012). No significant difference was found between PODCI and CHQ-PF28 scores.Conclusions: Children wearing customized arch-support insoles for 12 weeks improved their physical functional performance which belonged to the domain of activity in the ICF. However, using insoles did not affect the physical function and psychological well-being of children.ClinicalTrials.gov (NCT03198299), date of registration: June 2017, retrospectively registered.

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