Voxel-based structural magnetic resonance imaging (MRI) study of patients with early onset schizophrenia

The role of magnetic resonance imaging (MRI) in predicting disability in multiple sclerosis (MS) remains unclear. In this study 21 patients with primary and secondary progressive MS were reviewed 5 years following a serial MRI study of 6 months duration. In the secondary progressive group (n=11) there was a significant relationship between the occurrence of enhancing lesions and clinical relapses during the initial 6 months and increase in diability 5 years later. For both groups change in disability over the initial study period was predictive of outcome. These results suggest that the presence and frequency of gadolinium enhancement (a marker of inflammation) and changes in disability over a short period are predictive of future deterioration in progressive patients.

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Incidental Findings in Paranasal Sinuses and Mastoid Cells: A Cross-Sectional Magnetic Resonance Imaging (MRI) Study in a Pediatric Radiology Department

RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren ◽

10.1055/s-0032-1312861 ◽

2012 ◽

Vol 184 (07) ◽

pp. 629-634 ◽

Cited By ~ 11

Author(s):

T. von Kalle ◽

C. Fabig-Moritz ◽

H. Heumann ◽

P. Winkler

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Paranasal Sinuses ◽

Pediatric Radiology ◽

Incidental Findings ◽

Radiology Department ◽

Resonance Imaging ◽

Cross Sectional ◽

Magnetic Resonance Imaging Mri ◽

Mri Study

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Cavum septum pellucidum in schizophrenia, affective disorder and healthy controls: a magnetic resonance imaging study

Psychological Medicine ◽

10.1017/s0033291700028403 ◽

1993 ◽

Vol 23 (2) ◽

pp. 319-322 ◽

Cited By ~ 43

Author(s):

George J. Jurjus ◽

Henry A. Nasrallah ◽

Stephen C. Olson ◽

Steven B. Schwarzkopf

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Imaging Study ◽

Septum Pellucidum ◽

Healthy Controls ◽

Resonance Imaging ◽

Cavum Septum Pellucidum ◽

Clinical Difference ◽

Magnetic Resonance Imaging Mri ◽

Mri Study

SynopsisMany structural brain abnormalities have been described in schizophrenia, consistent with a neurodevelopmental model for this disease. We report here a study of the cavum septum pellucidum (CSP) in schizophrenia compared to control groups, as well as the clinical correlates of this congenital anomaly in schizophrenia. We conducted a magnetic resonance imaging (MRI) study to compare rates of CSP in schizophrenia (N = 67) v. psychiatric controls (bipolar and schizoaffective, N = 60) and healthy controls (N = 37). Of the controls 18·9 %, and of all psychotic subjects 18·1 % had a CSP of any size and there was no difference in the frequency of large CSP among the groups. Males had higher rates of CSP than females (25% v. 9·7%, P = 0·01) in all groups. Schizophrenics had higher CSP rates than affective patients (25%, v. 10%, P = 0·02). No clinical difference was found between schizophrenics with or without CSP.

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