Cavum septum pellucidum in schizophrenia, affective disorder and healthy controls: a magnetic resonance imaging study

SynopsisMany structural brain abnormalities have been described in schizophrenia, consistent with a neurodevelopmental model for this disease. We report here a study of the cavum septum pellucidum (CSP) in schizophrenia compared to control groups, as well as the clinical correlates of this congenital anomaly in schizophrenia. We conducted a magnetic resonance imaging (MRI) study to compare rates of CSP in schizophrenia (N = 67) v. psychiatric controls (bipolar and schizoaffective, N = 60) and healthy controls (N = 37). Of the controls 18·9 %, and of all psychotic subjects 18·1 % had a CSP of any size and there was no difference in the frequency of large CSP among the groups. Males had higher rates of CSP than females (25% v. 9·7%, P = 0·01) in all groups. Schizophrenics had higher CSP rates than affective patients (25%, v. 10%, P = 0·02). No clinical difference was found between schizophrenics with or without CSP.

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Cavum septum pellucidum in schizophrenia: A magnetic resonance imaging study

Psychiatry and Clinical Neurosciences ◽

10.1111/j.1440-1819.1996.tb01675.x ◽

1996 ◽

Vol 50 (3) ◽

pp. 125-128 ◽

Cited By ~ 18

Author(s):

TSUYOSHl FUKUZAKO ◽

HIROSHI FUKUZAKO ◽

SATOSHI KOUAMA ◽

TOMO HASHIGUCHI ◽

MORIKUNI TAKIGAWA

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Imaging Study ◽

Septum Pellucidum ◽

Magnetic Resonance Imaging Study ◽

Resonance Imaging ◽

Cavum Septum Pellucidum

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T1672 The Effects of Endogenous GLP-1 On Antro-Duodenal Contractility in the Fasted and Fed State: A Magnetic Resonance Imaging (MRI) Study

Gastroenterology ◽

10.1016/s0016-5085(09)62552-x ◽

2009 ◽

Vol 136 (5) ◽

pp. A-555

Author(s):

Elad Kaufman ◽

Mark Fox ◽

Michael Wyss ◽

Zsofia Forras-Kaufman ◽

Reto Treier ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Resonance Imaging ◽

Fed State ◽

Magnetic Resonance Imaging Mri ◽

Mri Study

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Dorsal Spinal Ligamentum Flavum Thickening: A Magnetic Resonance Imaging Study

Asian Spine Journal ◽

10.4184/asj.2018.12.1.47 ◽

2018 ◽

Vol 12 (1) ◽

pp. 47-51 ◽

Cited By ~ 1

Author(s):

Amarnath Chelladurai ◽

Suhasini Balasubramaniam ◽

Sarenya Preyah Anbazhagan ◽

Sathyan Gnanasihamani ◽

Sukumar Ramaswami

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Ligamentum Flavum ◽

Imaging Study ◽

Mean Value ◽

Resonance Imaging ◽

Magnetic Resonance Imaging Mri ◽

Compressive Myelopathy ◽

Relationship Of ◽

Dorsal Spinal

<sec><title>Study Design</title>A retrospective radiological study of the ligamentum flavum (LF).</sec><sec><title>Purpose</title>We determined the relationship of dorsal spinal LF thickening with age and sex using magnetic resonance imaging (MRI). We also determined whether LF thickening has a predominant tendency to occur at a specific dorsal level and on a specific side.</sec><sec><title>Overview of Literature</title>Many researchers have studied LF thickness at dorsal levels in patients with compressive myelopathy. However, there is a dearth of literature pertaining to the study of dorsal LF thickness in patients without myelopathy.</sec><sec><title>Methods</title>LF thickness was measured at dorsal levels from T1 to T12 on both sides using MRI in 100 individuals. The patients were divided into three groups based on age: 20 to 40, 41 to 60, and >60 years. On axial T2-weighted imaging at the mid-disc level, LF thickness was measured perpendicular to the lamina border, either at half the length of LF or at maximum thickness, whichever was greater.</sec><sec><title>Results</title>We found that LF thickness does not increase significantly with increasing age and there was no significant disparity in LF thickness between the sides and sexes. We also found that there was a significant increase in LF thickness at the T10–T11 level (mean value, 3.27±0.94 mm).</sec><sec><title>Conclusions</title>LF thickness does not appear to have any side/sex dominance. LF thickening has a predominant tendency to occur specifically at the T10–T11 level. This may be due to maximum tensile strength and mobility at this level. Because there is an increased tendency for LF thickening at the T10–T11 level, this may be used as a reference point for counting the vertebral levels.</sec>

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Clinical and Magnetic Resonance Imaging Predictors of Disability in Primary and Secondary Progressive Multiple Sclerosis

Multiple Sclerosis Journal ◽

10.1177/135245859600100406 ◽

1996 ◽

Vol 1 (4) ◽

pp. 218-222 ◽

Cited By ~ 43

Author(s):

NA Losseff ◽

DPE Kingsley ◽

WI McDonald ◽

DH Miller ◽

AJ Thompson

Keyword(s):

Magnetic Resonance Imaging ◽

Multiple Sclerosis ◽

Magnetic Resonance ◽

Initial Study ◽

Progressive Multiple Sclerosis ◽

Resonance Imaging ◽

Secondary Progressive ◽

Short Period ◽

Magnetic Resonance Imaging Mri ◽

Mri Study

The role of magnetic resonance imaging (MRI) in predicting disability in multiple sclerosis (MS) remains unclear. In this study 21 patients with primary and secondary progressive MS were reviewed 5 years following a serial MRI study of 6 months duration. In the secondary progressive group (n=11) there was a significant relationship between the occurrence of enhancing lesions and clinical relapses during the initial 6 months and increase in diability 5 years later. For both groups change in disability over the initial study period was predictive of outcome. These results suggest that the presence and frequency of gadolinium enhancement (a marker of inflammation) and changes in disability over a short period are predictive of future deterioration in progressive patients.

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