scholarly journals Post-operative blood pressure and 3-year major adverse cardiac events in Chinese patients undergoing PCI

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Lijun Gan ◽  
Dandan Sun ◽  
Yuntao Cheng ◽  
Deyang Wang ◽  
Fen Wang ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Inflection Point ◽  
Major Adverse Cardiac Events ◽  
Occurrence Rate ◽  
Curvilinear Relationship ◽  
Cardiac Events ◽  
Average Systolic Blood Pressure ◽  
Adverse Cardiac Events

Abstract Background There is no clear evidence for the target value of blood pressure control after Percutaneous coronary intervention (PCI). Therefore, our study was designed to explore the relationship between blood pressure after PCI and major adverse cardiac events (MACE) during 3-year follow-up. Methods This study is a prospective study. We included the patients who were diagnosed with acute coronary syndrome and underwent PCI stent implantation operation. The study initially collected information of 552 patients. The start and end times of the study are from January 1, 2017 to December 31, 2020. The independent variables of this study are the average systolic blood pressure and the average diastolic blood pressure after PCI. The dependent variable is the occurrence of MACE events in patients within 3 years after PCI. MACE is defined as acute myocardial infarction, recurring chest pain, heart failure, stroke, revascularization and cardiac death. Results A total of 514 subjects met the inclusion criteria. The average age of the study subjects is 61.92 ± 9.49 years old, of which 67.12% are male. 94 subjects had a MACE event within 3 years, and the occurrence rate was 18.29%. There is no significant non-linear or linear relationship between diastolic blood pressure and MACE events. There is a curvilinear relationship between the average systolic blood pressure of patients after PCI and MACE events within 3 years and the inflection point is 121. On the left side of the inflection point, the effect size and 95% CI are 1.09 and 1.01–1.18, respectively (P = 0.029). The impact size and 95% CI at the right inflection point were 1.00 and 0.98–1.02(P = 0.604), respectively. Conclusion There is a curvilinear relationship between systolic blood pressure and prognosis of patients after PCI. Under the premise of ensuring the safety of patients, maintaining lower blood pressure after surgery is beneficial to improve the prognosis of patients.

scholarly journals Post-Operative Blood Pressure in 24 Hours and 3-Year Major Adverse Cardiac Events in Chinese Patients Undergoing PCI

2021 ◽  
Author(s):  
Lijun Gan ◽  
Dandan Sun ◽  
Yuntao Cheng ◽  
Deyang Wang ◽  
Fen Wang ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Linear Relationship ◽  
Diastolic Blood Pressure ◽  
Inflection Point ◽  
Major Adverse Cardiac Events ◽  
Cardiac Events ◽  
Average Systolic Blood Pressure ◽  
Adverse Cardiac Events ◽  
Non Linear

Abstract Background: There is no clear evidence for the target value of blood pressure control within 24 hours after Percutaneous coronary intervention (PCI). Therefore, our study was designed to explore the relationship between blood pressure within 24 hours after PCI and major adverse cardiac events (MACE) during 3-year follow-up. Methods: This study is a prospective study. The study initially collected information of 552 patients. The start and end times of the study are from January 1, 2017 to December 31, 2020. The independent variables of this study are the average systolic blood pressure and the average diastolic blood pressure within 24 hours after PCI. The dependent variable is the occurrence of MACE events in patients within 3 years after PCI. Results: A total of 514 subjects met the inclusion criteria. The average age of the study subjects is 61.92 ± 9.49 years old, of which 67.12% are male. 94 subjects had a MACE event within 3 years, and the occurrence rate was 18.29%. There is no significant non-linear or linear relationship between diastolic blood pressure and MACE events. There is a curvilinear relationship between the average systolic blood pressure within 24 hours of patients after PCI and MACE events within 3 years and the inflection point is 134. On the left side of the inflection point, the effect size and 95% CI are 1.22 and 1.04-1.43, respectively (P=0.017). The impact size and 95% CI at the right inflection point were 0.96 and 0.83-1.11, respectively (P=0.604). Conclusion: There is a non-linear relationship between systolic blood pressure and the occurrence of MACE events in 3 years, and its inflection point is 134mmHg. In the case of ensuring patient safety, we should control the patient's systolic blood pressure within 24 hours after surgery.

ASSESSING THE OUTCOMES OF TREATMENT AND MANAGEMENT, 400 HYPERTENSIVE PATIENTS IN BONG SON GENERAL HOSPITAL, BINH DINH PROVINCE

2016 ◽  
pp. 31-40
Author(s):  
Long Nhon Phan ◽  
Van Minh Huynh ◽  
Thi Kim Nhung Hoang ◽  
Van Nham Truong
Keyword(s):  
Blood Pressure ◽  
Risk Stratification ◽  
Hypertensive Patient ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Blood Pressure Target ◽  
Average Risk ◽  
Hypertensive Patients ◽  
Average Systolic Blood Pressure ◽  
Complications Of Stroke

Objective: To evaluate the results of treatment achieved blood pressure goal (BP goal) and results of hypertensive patient management. Subjects and methods: A study of 400 hypertensive patient intervention, treatment and management after 2 year. To assess the results of BP target, monitor the use of medicines, the situation of hospitalization and complications of stroke. Results: Treatment: -100% of patients using diuretics and angiotensin-converting enzyme inhibitors (ACEIs), 33% of patients using angiotensin receptor blockers (ARBs), 46.25% of patients using calcium channel blockers (CCBs) and 19.5% of patients using beta-blocker. After 24 months of treatment: 50.5% of patients using 1 antihypertensive drug, 22% of patients using 2 drugs, 20.5% of patients using 3 drugs and 7% of patients taking more than 3 drugs. After 24 months of treatment: 91.75% achieved BP target and 8.25% fail. -Average risk stratification: 97.32% achieved BP target, hight risk stratification: 95.91% and very hight risk stratification: 73.03%. After 24 months of treatment. -Stage 1: 88.48% achieved BP target, stage 2: 92.85% achieved BP target and stage 3: 71.08% achieved BP target. After 24 months of treatment. -Hypertesive results before treatment were: 159.80 ± 20,22mmHg average systolic blood pressure and 82.97 ± 5,82mmHg average diastolic blood pressure. After treatment: average systolic blood pressure 125.38 ± 6,88mmHg and average diastolic blood pressure 79.83 ± 1,79mmHg. No adverse change in the index of tests about lipidemia, liver, kidney, glucomia and no recorded cases of drug side effects. Management of patients: -There were 89% non-medical examinational patients 1 month, 5.25% non-medical examinational patients 2 months, 4.25% non-medical examinational patients 3 months and 1.5% non-medical examinational patients 4 months. There were 93.5% drop pill 1 month, 3.25% drop pill 2 months, 4.25% drop pill 3 months and no patient drop pill over 3 months. In 24 months follow-up, 47% hospitalized inpatients <5 times, 44.5% hospitalized inpatients 5-10 times, 3% hospitalized inpatients 11-15 times, 4.75% hospitalized inpatients from 16-20 times and 0.75% hospitalized inpatients > 20 times. -There were 32.75% hospitalized inpatients for reasons of hypertension and 63.75% hospitalized inpatients for other common diseases. -There were a total of 11592 contacts directly by phone for medical advice, medical reminders and examinational reminders during 24 months of management. -There were 0.5% of patients stroked during 24 months of treatment and management. Conclusion: Treatment by protocol and management by phone directly for medical taking and re-examinational reminders is the best resulted method of achieving blood pressure target and reducing complications of stroke for hypertensive patients. Key word: : blood pressure target; risk stratification; treatment; management; stage; phone.

Effects of Aging on the Variability of Arterial Pressure in Essential Hypertensive Patients

1982 ◽  
Vol 63 (s8) ◽  
pp. 411s-414s ◽  
Author(s):  
Jun Ogawa ◽  
Shigeo Takata ◽  
Gakuji Nomura ◽  
Shiro Arai ◽  
Takayuki Ikeda ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Stroke Volume ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Pulse Pressure ◽  
Baroreflex Sensitivity ◽  
Peripheral Resistance ◽  
Resistance Index ◽  
Average Systolic Blood Pressure ◽  
Effects Of Aging

1. We studied the effects of aging on the variability of blood pressure in mild to moderate essential hypertensive subjects. 2. Cardiac index was greater and total peripheral resistance index was less in patients under 40 years (by an average of 1.06 litres min−1 m−2 and 9.23 mmHg 1−1 min−1 m−2) than in those over 40 respectively (P < 0.001 for each). 3. Pulse pressure/stroke volume was less by an average of 0.345 mmHg/ml in patients under 40 years than that in those over 40 (P < 0.001). Pulse pressure/stroke volume was correlated with age (r = 0.621), average systolic blood pressure (r = 0.623) and inversely with baroreflex sensitivity (r = −0.494). 4. Baroreflex sensitivity was less by an average of 3.1 ms/mmHg in patients over 30 years than in those under 30 (P < 0.025). Baroreflex sensitivity was inversely correlated with age (r = −0.617) and average systolic blood pressure (r = −0.589). 5. Beat by beat variability of systolic blood pressure was correlated with age (r = 0.460), particularly when the data of those in their twenties were excluded (r = 0.618), and significantly with pulse pressure/stroke volume (r = 0.650), average systolic blood pressure (r = 0.618) and inversely with baroreflex sensitivity (r = −0.477). These relationships were not observed for diastolic blood pressure. 6. Maximum difference in systolic blood pressure in a day was correlated with pulse pressure/stroke volume (r = 0.482) and average systolic blood pressure (r = 0.648) but not with baroreflex sensitivity. These relationships were not observed for diastolic blood pressure. 7. Variability of systolic blood pressure in patients over 30 years gradually increased with age. In contrast, those of systolic and diastolic blood pressures in subjects in their twenties were relatively large. This might be related to factors other than aging, presumably those which underlie the hyperdynamic circulatory state.

The Association of Febuxostat Compared With Allopurinol on Blood Pressure and Major Adverse Cardiac Events Among Adult Patients With Hyperuricemia: A Meta-analysis

2020 ◽  
Vol 76 (4) ◽  
pp. 461-471 ◽  
Author(s):  
Marie Barrientos-Regala ◽  
Renelene A. Macabeo ◽  
Rosemarie Ramirez-Ragasa ◽  
Noemi S. Pestaño ◽  
Felix E. R. Punzalan ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Meta Analysis ◽  
Adult Patients ◽  
Major Adverse Cardiac Events ◽  
Cardiac Events ◽  
Adverse Cardiac Events

scholarly journals The Effect of Methylphenidate and Atomoxetine on Heart Rate and Systolic Blood Pressure in Young People and Adults with Attention-Deficit Hyperactivity Disorder (ADHD): Systematic Review, Meta-Analysis, and Meta-Regression

2018 ◽  
Vol 15 (8) ◽  
pp. 1789 ◽  
Author(s):  
Edwin F. Liang ◽  
Samuel Z. Lim ◽  
Wilson W. Tam ◽  
Cyrus S. Ho ◽  
Melvyn W. Zhang ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Systolic Blood Pressure ◽  
Attention Deficit ◽  
Meta Analysis ◽  
Cardiac Events ◽  
Adverse Cardiac Events ◽  
Adolescents And Adults ◽  
Meta Regression ◽  
Pre Treatment

Objectives: This meta-analysis aims to study the effects of atomoxetine and methylphenidate on heart rate (HR), systolic blood pressure (SBP), and a number of adverse cardiac events on patients receiving treatment for attention-deficit hyperactive disorder (ADHD) in comparison to placebo and between atomoxetine and methylphenidate. Methods: We searched the following databases: PubMed, EMBASE, and ScienceDirect. Meta-analysis was performed on studies that examined the relationships between methylphenidate or atomoxetine and HR, SBP, as well as a number of adverse cardiac events. These studies were either placebo-controlled or comparison studies between methylphenidate and atomoxetine. Meta-regression identified patient- and treatment-related factors that may contribute to heterogeneity. Results: Twenty-two studies were included and the total number of participants was 46,107. Children/adolescents and adults treated with methylphenidate had more significant increases in post- vs. pre-treatment HR (p < 0.001) and SBP (p < 0.001) than those treated by placebo. Children and adolescents treated with atomoxetine had more significant increases post- vs. pre-treatment HR (p = 0.025) and SBP (p < 0.001) than those treated with methylphenidate. Meta-regression revealed mean age of participants, mean dose, and duration of atomoxetine and methylphenidate as significant moderators that explained heterogeneity. There were no differences in the number of adverse cardiac events between participants with methylphenidate treatment and placebo or atomoxetine. Conclusions: Children/adolescents and adults treated with methylphenidate resulted in significant increases in post- vs. pre-treatment HR and SBP as compared to placebo. Similarly, children and adolescents treated with atomoxetine had significant increases in post- vs. pre-treatment HR and SBP than those treated with methylphenidate. These findings have potential implications for continuous monitoring of HR and SBP throughout the course of treatment although the risk for adverse cardiac events were insignificant.

scholarly journals Association of long-term exposure to PM2.5 with hypertension prevalence and blood pressure in China: a cross-sectional study

BMJ Open ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. e050159
Author(s):  
Jiali Song ◽  
Yan Gao ◽  
Shuang Hu ◽  
Emanuela Medda ◽  
Guigang Tang ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Air Pollution ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Cardiac Events ◽  
Response Curves ◽  
Cross Sectional ◽  
Hypertension Prevalence ◽  
Increased Risk

ObjectiveEvidence of the effects of long-term fine particulate matter (PM2.5) exposure on hypertension and blood pressure is limited for populations exposed to high levels of PM2.5. We aim to assess associations of long-term exposure to PM2.5 with hypertension prevalence and blood pressure, and further explore the subpopulation differences and effect modification by participant characteristics in these associations in China.MethodsWe analysed cross-sectional data from 883 827 participants aged 35–75 years in the China Patient-Centred Evaluative Assessment of Cardiac Events Million Persons Project. Data from the monitoring station were used to estimate the 1-year average concentration of PM2.5. The associations of PM2.5 exposure with hypertension prevalence and blood pressure were investigated by generalised linear models, with PM2.5 included as either linear or spline functions.ResultsThe 1-year PM2.5 exposure of the study population ranged from 8.8 to 93.8 µg/m3 (mean 49.2 µg/m3). The adjusted OR of hypertension prevalence related to a 10 μg/m3 increase in 1-year PM2.5 exposure was 1.04 (95% CI, 1.02 to 1.05). Each 10 μg/m3 increment in PM2.5 exposure was associated with increases of 0.19 mm Hg (95% CI, 0.10 to 0.28) and 0.13 mm Hg (95% CI, 0.08 to 0.18) in systolic blood pressure and diastolic blood pressure, respectively. The concentration–response curves for hypertension prevalence and systolic blood pressure showed steeper slopes at higher PM2.5 levels; while the curve for diastolic blood pressure was U-shaped. The elderly, men, non-current smokers and obese participants were more susceptible to the exposure of PM2.5.ConclusionsLong-term exposure to PM2.5 is associated with higher blood pressure and increased risk of hypertension prevalence. The effects of PM2.5 on hypertension prevalence become more pronounced at higher PM2.5 levels. These findings emphasise the need to reduce air pollution, especially in areas with severe air pollution.

scholarly journals Efektifitas Jus Semangka Dan Jus Pepaya Terhadap Penurunan Tekanan Darah Penderita Hipertensi Di Puskesmas Kembaran 1 Banyumas

2020 ◽  
Vol 5 (2) ◽  
Author(s):  
Tri Oka Regita Cahyani ◽  
Ikhsan Mujahid
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Quantitative Methods ◽  
Statistical Tests ◽  
Public Health Care ◽  
Average Systolic Blood Pressure ◽  
Watermelon Juice ◽  
Significant Difference ◽  
In The Beginning

Objective:  To determine the effectiveness of watermelon juice and papaya juice on blood pressure in patients with hypertension at the Puskesmas (Public Health Care Center) Kembaran I Banyumas.Methods: This research uses quantitative methods with a quasi-experimental design with a pre-post group. The sample selection using a purposive sampling technique obtained 15 respondents in the watermelon juice group and 15 respondents in the papaya juice group. The statistical tests used are Paired t-test and independent t-testResults: The results of the study found that the average systolic blood pressure of the watermelon juice group was from 148.13 in the beginning to 138.93. The average diastolic blood pressure was 85.80 to 80.60. While the average systolic blood pressure of the papaya juice group was from 149.40 in the beginning to 145.67, the average diastolic blood pressure was from 84.20 to 80.80. There were significant differences in systolic and diastolic blood pressure before and after treatment in the watermelon juice and papaya juice groups with p0.05. There is a significant difference in the effectiveness of watermelon juice and papaya juice on the reduction of systolic and diastolic blood pressure with p0.05.Conclusion: Watermelon juice is more effective than papaya juice for reducing blood pressure in patients with hypertension at the Puskesmas Kembaran 1 Banyumas.

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