scholarly journals HIV virological non-suppression and its associated factors in children on antiretroviral therapy at a major treatment centre in Southern Ghana: a cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Adwoa K. A. Afrane ◽  
Bamenla Q. Goka ◽  
Lorna Renner ◽  
Alfred E. Yawson ◽  
Yakubu Alhassan ◽  
...  
Keyword(s):  
Viral Load ◽  
Previous History ◽  
Female Gender ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated ◽  
Study Recruitment ◽  
History Of ◽  
Study Participants

Abstract Background Children living with human immunodeficiency virus (HIV) infection require lifelong effective antiretroviral therapy (ART). The goal of ART in HIV-infected persons is sustained viral suppression. There is limited information on virological non-suppression or failure and its associated factors in children in resource limited countries, particularly Ghana. Methods A cross-sectional study of 250 children aged 8 months to 15 years who had been on ART for at least 6 months attending the Paediatric HIV clinic at Korle Bu Teaching hospital in Ghana was performed. Socio-demographic, clinical, laboratory and ART Adherence related data were collected using questionnaires as well as medical records review. Blood samples were obtained for viral load and CD4+ count determination. Viral load levels > 1000 copies/ml on ART was considered virological non-suppression. Logistic regression was used to identify factors associated with virological non-suppression. Results The mean (±SD) age of the study participants was 11.4 ± 2.4 years and the proportion of males was 53.2%. Of the 250 study participants, 96 (38.4%) had virological non-suppression. After adjustment for significant variables, the factors associated with non-suppressed viral load were female gender (AOR 2.51 [95% CI 1.04–6.07], p = 0.041), having a previous history of treatment of tuberculosis (AOR 4.95 [95% CI 1.58–15.5], p = 0.006), severe CD4 immune suppression status at study recruitment (AOR 24.93 [95% CI 4.92–126.31], p < 0.001) and being on a nevirapine (NVP) based regimen (AOR 7.93 [95% CI 1.58–1.15], p = 0.005). Conclusion The prevelance of virological non-suppression was high. Virological non-suppression was associated with a previous history of TB treatment, female gender, severe CD4 immune suppression status at study recruitment and being on a NVP based regimen. Early initiation of ART and phasing out NVP-based regimen might improve viral load suppression in children. In addition, children with a history of TB may need focused measures to maximize virological suppression.

scholarly journals HIV virological non-suppression and its associated factors amongst children on antiretroviral therapy at a major paediatric treatment centre in Southern Ghana: a cross-sectional study

2021 ◽  
Author(s):  
Adwoa K. A. Afrane ◽  
Bamenla Q. Goka ◽  
Lorna Renner ◽  
Alfred Edwin Yawson ◽  
Yakubu Alhassan ◽  
...  
Keyword(s):  
Viral Load ◽  
Previous History ◽  
Female Gender ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated ◽  
Study Recruitment ◽  
History Of ◽  
Study Participants

Abstract Background Children with human immunodeficiency virus (HIV) infection require lifelong effective Antiretroviral Therapy (ART). The aim of ART in HIV-infected persons is sustained viral suppression. There is limited information on virological non-suppression or failure and its associated factors in children in resource limited countries, particularly Ghana. Methods A cross-sectional study of 250 children aged 8 months to 15 years who had been on ART for at least 6 months attending the Paediatric HIV clinic at Korle Bu Teaching hospital in Ghana was performed. Socio-demographic, clinical, laboratory and ART Adherence related data were collected using questionnaires as well as medical records. Blood samples were obtained for viral load and CD4+ count determination. Viral load levels > 1000 copies/ml on ART was considered virological non-suppression. Logistic regression was used to identify factors associated with virological non-suppression. Results The mean (± SD) age of the study participants was 11.4 ± 2.4 years and the proportion of males was 53.2%. Of the 250 study participants, 96 (38.4%) had virological non-suppression. After adjustment for significant variables, the factors associated with non-suppressed viral load were female gender (AOR 2.51 [95% CI 1.04–6.07], p = 0.041), having a previous history of treatment of tuberculosis (AOR 4.95 [95% CI 1.58–15.5], p = 0.006), severe CD4 immune suppression status (CD4% < 15% / CD4+ count < 200 cells/mm 3) at study recruitment (AOR 24.93 [95% CI 4.92-126.31], p < 0.001) and being on a Nevirapine based regimen (AOR 7.93 [95% CI 1.58–1.15], p = 0.005). Conclusion The prevelance of virological non-suppression was high. Virological non-suppression was associated with a previous history of TB treatment, female gender, severe CD4 immune suppression status (CD4% <15% / CD4+ count < 200 cells/mm3), at study recruitment and being on a Nevirapine based regimen. Early initiation of ART and phasing out Nevirapine based regimen might improve viral load suppression in children. In addition, children with a history of TB may need focused measures to maximize virological suppression.

scholarly journals Magnitude and associated factors of caesarean section deliveries among women who gave birth in Southwest Ethiopia: institutional-based cross-sectional study

2021 ◽  
Vol 79 (1) ◽  
Author(s):  
Ayenew Mose ◽  
Haimanot Abebe
Keyword(s):  
Caesarean Section ◽  
Urban Area ◽  
Previous History ◽  
Cross Sectional Study ◽  
Multiple Pregnancies ◽  
Sectional Study ◽  
Cross Sectional ◽  
Southwest Ethiopia ◽  
Factors Associated ◽  
History Of

Abstract Background Caesarean section is a life-saving comprehensive obstetric procedure of women and newborn performed during childbirth-related complications and should be universally accessible for all pregnant mothers globally. Appropriate use of caesarean section can reduce maternal and perinatal mortality. However, inappropriate use of caesarean section can negatively affect infant health, women health, and future pregnancies. The magnitude and factors associated with caesarean section delivery were not consistent and will vary between different hospitals of Ethiopia. Hence, this study aimed at assessing the magnitude and factors associated with caesarean section deliveries in Southwest Ethiopia. Methods and Materials An institutional-based cross-sectional study was conducted from January 1 to February 29, 2020. A systematic random sampling technique was used to select 551 study participants. A pretested, structured, and face-to-face interview was used to collect data. Data were entered into Epi-data version 4.2.0 and exported to SPSS version 23 for analysis. Bivariate and multivariate analyses were used to identify factors associated with caesarean section deliveries. P values < 0.05 result were considered as a statistically significant association. Results The magnitude of caesarean section deliveries was found to be 32.5 % (95 % CI; 28.6%-36.7 %). Mothers resided in an urban area [AOR = 2.58, (95% CI; 1.66–4.01)], multiple pregnancies [AOR = 3.15, (95% CI; 1.89–5.23), malpresentation [AOR = 3.05, (95% CI; 1.77–5.24)], and previous history of caesarean section [AOR = 3.55, (95% CI; 2.23–5.64) were factors associated with caesarean section deliveries. Conclusions Caesarean section deliveries were found high in the study area. Mothers resided in an urban area, multiple pregnancies, malpresentation, and previous history of caesarean section were factors associated with caesarean section deliveries. Therefore, counselling of mothers on the risk of giving birth through elective caesarean section without absolute and relative medical indications and giving enough time for the trial of vaginal birth after caesarean section are recommended.

scholarly journals Burden of Pelvic Girdle Pain During Pregnancy Among Women Attending Ante-Natal Clinic, Ethiopia: A Cross-Sectional Study

2020 ◽  
Author(s):  
Moges Gashaw Getnet ◽  
Solomon Gedlu ◽  
Balamurugan Janakiraman
Keyword(s):  
Pregnant Women ◽  
Maternal Morbidity ◽  
Previous History ◽  
Cross Sectional Study ◽  
Pelvic Girdle ◽  
Pelvic Girdle Pain ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated ◽  
History Of

Abstract Background: Pelvic girdle pain (PGP) is a commonly reported maternal morbidity that negatively impacts the well-being of women during pregnancy and extends long term into the post-partum period. The burden of maternal morbidity; including pregnancy-related PGP; has been overlooked in Ethiopia to date. This study aimed to determine the prevalence and identify factors associated with pelvic girdle pain during pregnancy in North West Ethiopia.Methods: A hospital-based cross-sectional study was conducted among pregnant women visiting the antenatal care clinic in Obstetrics ‘outpatient department at the University of Gondar comprehensive specialized hospital in Gondar. Data were collected by interview method using structured questionnaires, patient medical record reviews, and physical measurements. Univariate and multivariable logistic regression model analyses were used to identify factors associated with PGP. Results: A total of 424 participants with gestational ages ranging from 6 to 39 weeks participated in this study. The age of the study participants ranged from 18 to 44 years with a mean age of (27 ±4.6 years). The overall cumulative prevalence of pelvic girdle pain among pregnant women was 103 (24.3%), 95% CI (20.3, 28.8). The major associated factors with pelvic girdle pain were previous history of pelvic girdle pain (AOR 16.08; 95% CI, 8.47-30.51), previous history of back pain (AOR 1.66; 95% CI, 1.5-4.24) and having children (AOR 1.42; 95% CI, 1.29-3.76).Conclusion: One-quarter of pregnant Ethiopian women reported pelvic girdle pain. Many respondents endured pain on multiple occasions and association with the previous history of PGP might be an episode of relapse. PGP must be considered a major pregnancy-related morbidity, and progress in the intervention of PGP is vital to enhance the quality of life in this population.

Malaria among migrants in a university hospital in Colombia during 2018: A case series

2020 ◽  
pp. 004947552098130
Author(s):  
Fabián R Carreño-Almánzar ◽  
Adán Coronado-Galán ◽  
Sonia A Cala-Gómez ◽  
Agustín Vega-Vera
Keyword(s):  
Latin American ◽  
Previous History ◽  
Case Series ◽  
Cross Sectional Study ◽  
Imported Malaria ◽  
University Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
History Of ◽  
Clinical Profiles

Imported malaria has increased in Colombia since 2015 and has been attributed to migrants coming from Venezuela. We present a series of malaria cases, nested in a retrospective cross-sectional study between 2017 and 2018, aimed at calculating the prevalence of medical diseases among immigrants in a University Hospital in Colombia. Among 154 immigrants admitted for medical causes between 2017 and 2018, 8 were diagnosed with malaria, all due to Plasmodium vivax. Of these, seven had uncomplicated malaria, five had a previous history of malaria, one was critically ill, but none died. We highlight that, similar to other case series of imported malaria, Latin American migrants were young, with similar clinical profiles, having a low proportion of severe cases, and P. vivax was the most frequent cause.

Factors influencing breast cancer awareness: a cross-sectional study in China

2020 ◽  
Vol 9 (10) ◽  
pp. 679-689
Author(s):  
Na Liu ◽  
Ping Li ◽  
Jie Wang ◽  
Ping-ping Guo ◽  
Xue-hui Zhang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Health Information ◽  
Information Literacy ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cancer Awareness ◽  
Cross Sectional ◽  
Breast Cancer Awareness ◽  
History Of ◽  
Study Participants

Aim: This study aimed to explore the factors that influence breast cancer awareness. Materials & methods: A community-based cross-sectional study was conducted between January and April 2019 in Changchun, Jilin Province, China. Results: A total of 274 women were recruited for this cross-sectional study. Participants had a moderate level of breast cancer awareness (median = 76.50 [68.75, 84.00]). Women in the action/maintenance stages reported higher breast cancer awareness (p = 0.044). Women's breast cancer awareness was positively associated with high health information literacy level, husbands' higher educational degrees, seeing doctors after detecting abnormal breast changes and living within a short distance from the nearest hospital. Conclusion: History of screening and higher health information literacy levels are important positive factors linked to higher breast cancer awareness.

scholarly journals Relationship of ABO and Rh blood groups with history of gastritis in the undergraduate medical and dental students: a cross-sectional study

2017 ◽  
Vol 13 (4) ◽  
pp. 372-377
Author(s):  
Nilu Manandhar ◽  
Kushal Bhattarai
Keyword(s):  
Blood Group ◽  
Cross Sectional Study ◽  
Dental Students ◽  
Blood Groups ◽  
Sectional Study ◽  
Cross Sectional ◽  
History Of ◽  
Second Year ◽  
Study Participants ◽  
Medical And Dental Students

Background & Objectives: The various ABO and Rh blood groups with different distribution frequencies in the general population have been found to be associated with different diseases, most notably gastritis. Many studies have claimed Rh groups to be indifferent to such association. Nonetheless, ABO group is found to linked with chronic gastritis. The aim of this study was to estimate the frequencies of ABO and Rh blood groups and the gastritis amongst the first and second year undergraduate medical and dental students; and to study their relationships. Materials & Methods: In a descriptive, cross-sectional study, 247 study participants were enrolled. After procuring clearance from the institutional review committee and the informed and written consent from the study participants, data collection was done on the variables, year of study (first or second year), gender, blood groups (ABO and Rh) and history of gastritis (present or absent).Results: Blood group O was the commonest (n=99; 40.1%) followed by group B (n=77; 31.2%). Similarly, 239 (96.8%) participants were Rh-positive as compared to 8 (3.2%) Rh-negative. Interestingly, 46 (18.6%) of the participants reported positive history of gastritis. Participants with blood group O had the greatest odds (OR=1.64) of having history of gastritis compared with those with other blood groups combined. Distribution of study participants based on gender and history of gastritis in either systems of blood grouping shoed no significant difference in their proportions (p>0.05). Conclusion: In light of the above findings, further longitudinal studies can be designed to better asses the relationship.

scholarly journals Factors associated with the consumption of chlorine dioxide to prevent and treat COVID-19 in the Peruvian population: a cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
David R. Soriano-Moreno ◽  
Daniel Fernandez-Guzman ◽  
Fabricio Ccami-Bernal ◽  
Cristhian Rojas-Miliano ◽  
Wendy Nieto-Gutierrez
Keyword(s):  
Chlorine Dioxide ◽  
Medical Information ◽  
Cross Sectional Study ◽  
Consumption Pattern ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated ◽  
Information Strategies ◽  
The Family ◽  
History Of

Abstract Background Chlorine dioxide has been promoted as an alternative for the prevention and treatment of COVID-19, especially in Peru, despite the lack of evidence to support its efficacy. This study aimed to evaluate the factors associated with chlorine dioxide consumption in the Peruvian population. Methods Analytical cross-sectional study. An adult Peruvian population was evaluated where chlorine dioxide consumption was divided into two groups according to the purpose of use: as prevention (individuals without COVID-19 history) and as treatment (individuals with COVID-19 history). The associated factors in each group were evaluated using Poisson regressions with the bootstrapping resampling method. Results Of 3610 participants included, 3213 reported no history of COVID-19, and 397 had been infected. The prevalence of chlorine dioxide consumption to prevent or treat COVID-19 was 8 and 16%, respectively. Factors either positively or negatively associated with chlorine dioxide consumption for prevention were male sex (aPR: 1.36; 95% CI: 1.09–1.71), being an adult or older adult (aPR: 0.54; 95% CI: 0.35–0.82), having a health sciences student within the family unit (aPR: 1.38; 95% CI: 1.02–1.87), using medical information as the main source of information of COVID-19 (aPR: 0.57; 95% CI: 0.40–0.80), having comorbidities for COVID-19 (aPR: 1.36; 95% CI: 1.01–1.82), considering COVID-19 dangerous and deadly (aPR: 0.57; 95% CI: 0.45–0.74), using medications (aPR: 1.59; 95% CI: 1.25–2.06) and plants to prevent COVID-19 (aPR: 1.69; 95% CI: 1.21–2.36), considering chlorine dioxide ineffective (aPR: 0.18; 95% CI: 0.18–0.24), and being uninformed of its efficacy (aPR: 0.21; 95% CI: 0.16–0.28). In addition, factors associated with chlorine dioxide consumption for treatment were considering COVID-19 dangerous and deadly (aPR: 0.56; 95% CI: 0.33–0.96), considering chlorine dioxide ineffective (aPR: 0.22; 95% CI: 0.12–0.42), and being uninformed of its efficacy (aPR: 0.15; 95% CI: 0.07–0.32). Conclusions The prevalence of chlorine dioxide consumption to treat COVID-19 was higher than prevent. It is important to apply information strategies, prioritizing population groups with certain characteristics that are associated with a higher consumption pattern.

scholarly journals Depression in Acute Coronary Syndrome Patients: A Cross-sectional Study in Malaysia

2020 ◽  
Author(s):  
Wan Nor Asyikeen Wan Adnan ◽  
Siti Azrin Ab Hamid ◽  
Zatul Rathiah Sulong ◽  
Mohd Hashairi Fauzi
Keyword(s):  
Acute Coronary Syndrome ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Female Gender ◽  
Cross Sectional Study ◽  
Ischemic Heart ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated ◽  
Coronary Syndrome

Background and purpose: Linked with high mortality rate, depression is common among acute coronary syndrome (ACS) patients. The current study sought to identify the factors associated with depression among ACS patients in Malaysia. Materials and Methods: A cross-sectional study was conducted on 400 ACS patients in two Malaysian hospitals: Hospital Universiti Sains Malaysia (USM), Kelantan and Hospital Sultanah Nur Zahirah (HSNZ), Terengganu. ACS patients were included if they were above 18 years of age, able to read and/or write in Bahasa Melayu language and had informed consent. Patients were excluded if they were intubated, had an altered mental status, mental retardation and had psychological problems prior to ACS. Depression in this study was defined as having dysphoria, hopelessness, devaluation of life, self-deprecation, lack of interest or involvement, anhedonia, and inertia among ACS patients. A questionnaire was distributed to all 400 ACS patients. Simple and multiple logistic regressions were used for data analysis. Results: The mean (standard deviation) age of ACS patients was 60.4 (11.3) years at Hospital USM and 61.2 (10.4) years at HSNZ. Nearly all of the depressive-ACS patients were Malay (79.4%), 85.9% were male, and 79.7% were married. Approximately 87.7% of depressive-ACS patients had ischemic heart disease, 87.1% had stroke, 83.4% had hyperlipidaemia, 81.8% had diabetes mellitus, and 80.7% had hypertension. The factors associated with depression were female gender (adjusted odd ratio (OR): 2.48, 95% confidence interval (CI): 1.50, 4.10, p<0.001) and ischemic heart disease (adjusted OR: 2.44, 95% CI: 1.41, 4.25, p=0.002). Conclusion: The results showed that female gender and ischemic heart disease were the most significant associated factors of depression among ACS patients.

scholarly journals Risk factors associated with hospital emergency visits among asthmatic schoolboys in Saudi Arabia

2002 ◽  
Vol 08 (01) ◽  
pp. 31-41
Author(s):  
K. M. Al Dawood
Keyword(s):  
Cross Sectional Study ◽  
Emergency Room Visits ◽  
Sectional Study ◽  
Hospital Emergency ◽  
Cross Sectional ◽  
Emergency Visits ◽  
Positive History ◽  
Factors Associated ◽  
Hospital Emergency Room ◽  
History Of

This cross-sectional study was carried out to determine the prevalence of a positive history of hospital emergency visits [HHEV] among asthmatic Saudi schoolboys. Data were collected using self-administered questionnaires to parents. The prevalence rate for positive HHEV among questionnaire-diagnosed asthmatic boys [QDAs] was 65.0%. Factors associated with positive HHEV among QDAs were determined. Modifying the preventable factors associated with the total number of hospital emergency room visits is expected to decrease the severity and the disability of this disease.

scholarly journals THE EPIDEMIOLOGICAL PATTERN OF FACTORS ASSOCIATED WITH ISCHEMIC STROKE IN PATIENTS UNDER 50 YEARS OF AGE: A CROSS-SECTIONAL STUDY

2021 ◽  
Vol 11 (3) ◽  
pp. 9-13
Author(s):  
Nourollah Ramroodi ◽  
Seyed Mehdi Hashemi ◽  
Mehrdad Ramroudi
Keyword(s):  
Blood Pressure ◽  
Heart Disease ◽  
Ischemic Stroke ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated ◽  
History Of ◽  
Epidemiological Pattern ◽  
The Mean

Objective: The aim of the present study was to investigate the epidemiological pattern of factors associated with ischemic stroke among patients under 50 years old. Methods: The present cross-sectional study was performed on 197 Stroke patients. Individuals with confirmed ischemic stroke based on of CT scan were included in the study. Demographic information included age, sex, history of smoking, place of residence, season of disease incidence, history of contraceptive use in women, history of hypertension, having high blood pressure at the onset of diabetes, hyperlipidemia, heart disease and patient weight. Finally, the collected data was analyzed using SPSS ver. 22. Results: The mean age of participants was 40.18 years. The mean weight, height, body mass index (BMI) were 79.83, 168.63, and 28.12, respectively. A total of 60.4% of the participants were male and 39.6% were female. Moreover, 66.9% were urban residents, 38.6% had complications in winter, 67% were smokers, and 50% used contraceptives. The history of hypertension, diabetes, hyperlipidemia, and heart disease was seen in 69%, 49.7, 66%, and 73.6% of cases, respectively. Also, 53.8% of patients had high blood pressure upon admission. Conclusion: The present study showed that a history of heart disease and a history of hypertension in the past and nicotine use are very common in people with stroke. Considering the above mentioned epidemiological factors, it is recommended to prioritize the mentioned factors when identifying new cases

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