scholarly journals Low agreement between modified-Schwartz and CKD-EPI eGFR in young adults: a retrospective longitudinal cohort study

2018 ◽  
Vol 19 (1) ◽  
Author(s):  
Michael Webster-Clark ◽  
Byron Jaeger ◽  
Yi Zhong ◽  
Guido Filler ◽  
Ana Alvarez-Elias ◽  
...  
BMJ Open ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. e038471
Author(s):  
Rachel M Taylor ◽  
Lorna A Fern ◽  
Julie Barber ◽  
Javier Alvarez-Galvez ◽  
Richard Feltbower ◽  
...  

ObjectivesIn England, healthcare policy advocates specialised age-appropriate services for teenagers and young adults (TYA), those aged 13 to 24 years at diagnosis. Specialist Principal Treatment Centres (PTC) provide enhanced TYA age-specific care, although many still receive care in adult or children’s cancer services. We present the first prospective structured analysis of quality of life (QOL) associated with the amount of care received in a TYA-PTCDesignLongitudinal cohort study.SettingHospitals delivering inpatient cancer care in England.Participants1114 young people aged 13 to 24 years newly diagnosed with cancer.InterventionExposure to the TYA-PTC defined as patients receiving NO-TYA-PTC care with those receiving ALL-TYA-PTC and SOME-TYA-PTC care.Primary outcomeQuality of life measured at five time points: 6, 12, 18, 24 and 36 months after diagnosis.ResultsGroup mean total QOL improved over time for all patients, but for those receiving NO-TYA-PTC was an average of 5.63 points higher (95% CI 2.77 to 8.49) than in young people receiving SOME-TYA-PTC care, and 4·17 points higher (95% CI 1.07 to 7.28) compared with ALL-TYA-PTC care. Differences were greatest 6 months after diagnosis, reduced over time and did not meet the 8-point level that is proposed to be clinically significant. Young people receiving NO-TYA-PTC care were more likely to have been offered a choice of place of care, be older, from more deprived areas, in work and have less severe disease. However, analyses adjusting for confounding factors did not explain the differences between TYA groups.ConclusionsReceipt of some or all care in a TYA-PTC was associated with lower QOL shortly after cancer diagnosis. The NO-TYA-PTC group had higher QOL 3 years after diagnosis, however those receiving all or some care in a TYA-PTC experienced more rapid QOL improvements. Receipt of some care in a TYA-PTC requires further study.


2017 ◽  
Vol 23 (8) ◽  
pp. 573.e1-573.e7 ◽  
Author(s):  
M.B. van Ravenhorst ◽  
M.W. Bijlsma ◽  
M.A. van Houten ◽  
V.M.D. Struben ◽  
A.S. Anderson ◽  
...  

Allergy ◽  
1996 ◽  
Vol 51 (11) ◽  
pp. 804-810 ◽  
Author(s):  
J. K. Peat ◽  
B. G. Toeile ◽  
J. Dermand ◽  
R. Berg ◽  
W. J. Britton ◽  
...  

2020 ◽  
Author(s):  
Amy Nivette ◽  
Denis Ribeaud ◽  
Aja Louise Murray ◽  
Annekatrin Steinhoff ◽  
Laura Bechtiger ◽  
...  

Background: Do young adults have low compliance rates with public health measures aimed at curbing the spread of Coronavirus disease 2019 (COVID-19)? This paper leverages a prospective-longitudinal cohort study with data before and during the pandemic to examine this question.Methods: Data came from an ongoing cohort study (n=737). Non-compliance with public health measures and concurrent correlates were measured at age 22. Antecedent sociodemographic, social, and psychological factors were measured at ages 15-20.Findings: Young adults generally complied with COVID-19 public health measures, although compliance with some measures (e.g., cleaning/disinfecting mobile phones, standing 1.5-2 meters apart) was relatively lower. Non-compliance, especially with hygiene-related measures, was more prevalent in males, and in individuals with higher education, higher SES, and a non- migrant background. Non-compliance was associated with “antisocial potential,” including pre-pandemic low acceptance of moral rules, legal cynicism, low shame/guilt, low self-control, engagement in delinquent behaviors, and association with delinquent peers. Young adults with low trust, including in the government’s measures for fighting the virus, also complied less.Interpretation: In order to increase voluntary compliance with COVID-19 measures, public health campaigns should implement strategies that foster moral obligation and trust in authorities, or leverage trustworthy individuals in the community to disseminate information. For young adults with low self-control, self-monitoring, environmental restructuring, or nudging may increase compliance. Long-term investments into integrating antisocial youth into society may decrease rule-breaking behaviors, including during pandemics when compliance saves lives.


2021 ◽  
Vol 268 ◽  
pp. 113370 ◽  
Author(s):  
Amy Nivette ◽  
Denis Ribeaud ◽  
Aja Murray ◽  
Annekatrin Steinhoff ◽  
Laura Bechtiger ◽  
...  

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Alison E. Cuellar ◽  
Leah M. Adams ◽  
Lilian de Jonge ◽  
Virginia Espina ◽  
Laurette Espinoza ◽  
...  

Abstract Background Young adulthood is a period of increasing independence for the 40% of young adults enrolled in U.S. colleges. Previous research indicates differences in how students’ health behaviors develop and vary by gender, race, ethnicity, and socioeconomic status. George Mason University is a state institution that enrolls a highly diverse student population, making it an ideal setting to launch a longitudinal cohort study using multiple research methods to evaluate the effects of health behaviors on physical and psychological functioning, especially during the COVID-19 pandemic. Results Mason: Health Starts Here was developed as a longitudinal cohort study of successive waves of first year students that aims to improve understanding of the natural history and determinants of young adults’ physical health, mental health, and their role in college completion. The study recruits first year students who are 18 to 24 years old and able to read and understand English. All incoming first year students are recruited through various methods to participate in a longitudinal cohort for 4 years. Data collection occurs in fall and spring semesters, with online surveys conducted in both semesters and in-person clinic visits conducted in the fall. Students receive physical examinations during clinic visits and provide biospecimens (blood and saliva). Conclusions The study will produce new knowledge to help understand the development of health-related behaviors during young adulthood. A long-term goal of the cohort study is to support the design of effective, low-cost interventions to encourage young adults’ consistent performance of healthful behaviors, improve their mental health, and improve academic performance.


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