scholarly journals Comparison of birth weights of neonates of mothers receiving vs. not receiving zinc supplement at pregnancy

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hassan Boskabadi ◽  
Gholamali Maamouri ◽  
Javad Akhondian ◽  
Farah Ashrafzadeh ◽  
Abbas Boskabadi ◽  
...  
Keyword(s):  
Birth Weight ◽  
Essential Element ◽  
Serum Zinc ◽  
Zinc Level ◽  
Maternal Serum ◽  
Control Group ◽  
Serum Zinc Level ◽  
Zinc Supplement ◽  
Neonatal Birth Weight ◽  
Zinc Supplements

Abstract Background Zinc is an essential element for normal embryogenesis and embryonic and neonatal development. Therefore, we compared the birth weights of neonates born to mothers who consumed zinc supplement during pregnancy with that of neonates born to mothers who did not. Methods In a cross-sectional study, we divided 200 pregnant mothers into two groups: case group (mothers receiving zinc supplement during pregnancy) and control group (mothers not receiving zinc supplement during pregnancy) Then, the neonate’s cord zinc level and mother’s serum level were measured and neonate’s growth charts (weight, height and head circumference)were completed. Results In this study, both groups of mothers were observed to have zinc deficiency; 35% of the mothers who consumed zinc supplements and 81% of the mothers who did not consume zinc supplements (P < 0.001). Based on the results, maternal serum of zinc (P < 0.001), neonatal birth weight (P = 0.008), maternal age (P < 0.001) and parity (P < 0.01) in zinc-supplemented group were higher. Neonatal birth weight was associated moderately with mother’s zinc serum levels and poorly with neonatal serum zinc levels. Conclusion Zinc consumption during pregnancy increases serum zinc level of mother and neonatal weight. Neonatal weight has a higher correlation to maternal serum zinc level.

scholarly journals Zinc Serum Maternal Levels as a Risk Factor for Preeclampsia

2021 ◽  
Vol 5 (4) ◽  
pp. 1110-1118
Author(s):  
Abarham Martadiansyah ◽  
Peby Maulina ◽  
Putri Mirani ◽  
Tia Kaprianti ◽  
Theodorus
Keyword(s):  
Pregnant Women ◽  
Dietary Habits ◽  
Serum Zinc ◽  
Zinc Level ◽  
Maternal Serum ◽  
Control Group ◽  
Case Group ◽  
Serum Zinc Level ◽  
Zinc Levels ◽  
Serum Zinc Levels

Background. Preeclampsia is defined as gestational hypertension and proteinuria which can be measured by the elevation of liver transaminases to twice normal concentration, and the symptoms of increased intracranial pressure such as dizziness, blurred vision, and seizures. Zinc is an essential mineral for many biological functions and one of the trace elements that is directly involved in the oxidative/antioxidant balance, a pathogenesis process in preeclampsia that is highly dependent on dietary habits and supplements. This study was aimed to assess the association between serum zinc level with preeclampsia (PE). Methods: This observational, case-control study was performed on 90 women with singleton pregnancies at 28 to 42 weeks of gestation which were referred to the Department of Obstetrics and Gynecology, Dr. Mohammad Hoesin General Hospital, Palembang, between August 2020 to November 2020. 30 pregnant women with PE were selected as cases and 60 healthy pregnant women were selected as controls. Maternal serum zinc samples were collected. The collected data were entered into the master table. Tabulation, coding, and statistical data analysis were performed using SPSS version 20.0 for Windows. Results: The mean serum zinc levels in the case group and control group were 43,90 ± 15,79 µg/dL (ranged from 15 to 86 µg/dL) and 48,77 ± 10,54 µg/dL (ranged from 22 to 83 µg/dL), respectively. A value of serum zinc levels with the best sensitivity and specificity was 45,5 µg/dL. Conclusion: There was a significant association between maternal serum zinc level with PE. The risk of PE was 3,2 times higher in pregnant women with serum zinc levels of ≤45,5 mcg/dL compared to pregnant women with serum zinc levels of >45,5 mcg/dL. In this case it is necessary to supplement zinc earlier in pregnancy to reduce the risk of preeclampsia.

scholarly journals Zinc Serum Maternal Levels as a Risk Factor for Preeclampsia

2021 ◽  
Vol 5 (7) ◽  
pp. 693-701
Author(s):  
Abarham Martadiansyah ◽  
Peby Maulina ◽  
Putri Mirani ◽  
Tia Kaprianti ◽  
Theodorus
Keyword(s):  
Pregnant Women ◽  
Dietary Habits ◽  
Serum Zinc ◽  
Zinc Level ◽  
Maternal Serum ◽  
Control Group ◽  
Case Group ◽  
Serum Zinc Level ◽  
Zinc Levels ◽  
Serum Zinc Levels

Background. Preeclampsia is defined as gestational hypertension and proteinuria which can be measured by the elevation of liver transaminases to twice normal concentration, and the symptoms of increased intracranial pressure such as dizziness, blurred vision, and seizures. Zinc is an essential mineral for many biological functions and one of the trace elements that is directly involved in the oxidative/antioxidant balance, a pathogenesis process in preeclampsia that is highly dependent on dietary habits and supplements. This study was aimed to assess the association between serum zinc level with preeclampsia (PE). Methods: This observational, case-control study was performed on 90 women with singleton pregnancies at 28 to 42 weeks of gestation which were referred to the Department of Obstetrics and Gynecology, Dr. Mohammad Hoesin General Hospital, Palembang, between August 2020 to November 2020. 30 pregnant women with PE were selected as cases and 60 healthy pregnant women were selected as controls. Maternal serum zinc samples were collected. The collected data were entered into the master table. Tabulation, coding, and statistical data analysis were performed using SPSS version 20.0 for Windows. Results: The mean serum zinc levels in the case group and control group were 43,90 ± 15,79 µg/dL (ranged from 15 to 86 µg/dL) and 48,77 ± 10,54 µg/dL (ranged from 22 to 83 µg/dL), respectively. A value of serum zinc levels with the best sensitivity and specificity was 45,5 µg/dL. Conclusion: There was a significant association between maternal serum zinc level with PE. The risk of PE was 3,2 times higher in pregnant women with serum zinc levels of ≤45,5 mcg/dL compared to pregnant women with serum zinc levels of >45,5 mcg/dL. In this case it is necessary to supplement zinc earlier in pregnancy to reduce the risk of preeclampsia.

scholarly journals Preterm Delivery: Role of Zinc

1970 ◽  
Vol 5 (1) ◽  
pp. 27-33 ◽  
Author(s):  
Masuda Sultana ◽  
Nasim Jahan ◽  
Nayma Sultana ◽  
Shamshad Begum Quraishi ◽  
Tasrina Rabeya Chowdhury
Keyword(s):  
Birth Weight ◽  
Preterm Delivery ◽  
Serum Zinc ◽  
Zinc Level ◽  
Full Term ◽  
Preterm Neonates ◽  
Control Group ◽  
Serum Zinc Level ◽  
Cross Sectional ◽  
Term Neonates

Background: Preterm delivery is a very challenging obstetric complication in Bangladesh. Reducedserum zinc (Zn) concentration of the pregnant mother may have some role in causing preterm delivery.Objectives: To measure serum zinc level in preterm delivery mother and their respective neonates toobserve their status. Methods: This cross sectional study was carried out in the Department ofPhysiology, Sir Salimullah Medical College, Mitford Hospital, Dhaka, during the period of 1st Januaryto 31st December 2009. A total 136 subjects were included in this study, of whom 27 were full termdelivery mother with their respective neonates (group B), treated as control group and another 27were preterm delivery mothers with their respective neonates (group C), treated as study group. Ageranged of preterm and full term mother were from 20-40 years. Again, 28 non pregnant women with agerange from 20-30 years were taken as reference value (groupa A). Statistical analysis was done byusing appropriate method as applicable. Results: Mean serum zinc level was significantly (p<0.001)lower in preterm mother in comparison to that of full term mother and also in preterm neonates thanthat of full term neonates. Serum total protein and albumin were significantly (p<0.001) lower inpreterm mother than those of full term mother and also in preterm neonates than those of theirrespective mothers and full term neonates. Again, maternal serum zinc level showed positive correlationwith birth weight of neonates and also with zinc concentration of neonatal blood. Conclusions: Thepresent study revealed a lower level of serum zinc in pre-term delivery mother and their neonates.These hypozincemia may be responsible for low birth weight of the fetus.Key Words: Zinc; pretermDOI: 10.3329/jbsp.v5i1.5415J Bangladesh Soc Physiol. 2010 June; 5(1): 27-33

scholarly journals Serum Zinc Level at Term Pregnancy and Newborn Anthropometry

2016 ◽  
Author(s):  
Irma Seriana ◽  
Yusrawati Yusrawati ◽  
Gustina Lubis
Keyword(s):  
Birth Weight ◽  
Head Circumference ◽  
Serum Zinc ◽  
Zinc Level ◽  
Birth Length ◽  
Anthropometric Measurement ◽  
Term Pregnancy ◽  
Serum Zinc Level ◽  
Average Birth Weight ◽  
Newborn Anthropometry

Objective: To determine the relationship between serum zinc level at term pregnancy and newborn anthropometry. Methods: This study is an observational study with cross-sectional design. Serum zinc level at term pregnancy was measured and then anthropometric measurement was done to the newborn, including birth weight, birth length and head circumference at birth. The data were statistically analyzed using regression correlation test. Results: Mean serum zinc level at term pregnancy is 36.01 μg/dl (SD=18.34 μg/dl), the average birth weight is 3158 gr (SD=480.4 gr), the average birth length is 48.42 cm (SD=1.75 cm) and the average head circumference at birth is 33.13 cm (SD=1.14 cm). There was no statistically significant relationship between serum zinc levels at term pregnancy and birth weight (p-value=0.152). Meanwhile, there are statistically significant relationships between serum zinc level at term pregnancy with birth length and head circumference with pvalue 0.026 and 0.012, respectively. Conclusion: Serum zinc level at term pregnancy is correlated with birth length and head circumference, but is not correlated with birth weight. [Indones J Obstet Gynecol 2015; 3-4: 190-195] Keywords: birth length, birth weight, head circumference at birth, serum zinc level, term pregnancy

scholarly journals Effects of Iron and Amloki (EmblicaOfficinalis) on Serum Zinc Level in Anaemia with Pregnancy

2021 ◽  
Vol 49 (1) ◽  
pp. 33-37
Author(s):  
Tahmina Akter ◽  
Qazi Shamima Akther ◽  
Saima Haque Lisa ◽  
Mst Ariza Sultana ◽  
Farhana Sultana ◽  
...  
Keyword(s):  
Side Effects ◽  
Iron Deficiency Anaemia ◽  
Iron Supplementation ◽  
Serum Zinc ◽  
Zinc Level ◽  
Control Group ◽  
Serum Zinc Level ◽  
Deficiency Anaemia ◽  
Medical College ◽  
And Control

Pregnancy is associated with several trace elements deficiency in developing countries. Supplementation of iron in iron deficiency anaemia (IDA) has several side effects including alterations of serum zinc level. Traditionally, amloki is used as a well known supplement in pregnancy, which is rich in trace elements.To determine the effects of iron and amloki on serum zinc level in IDA with pregnancy. The study was a non blind, non random sampling interventional type of clinical trial. This study was performed in the Department of Physiology, Dhaka Medical College, Dhaka on 43 pregnant women between 13th to 20th weeks of gestation with IDA from July 2016 to June 2017.  They were recruited from Outpatient Department of Obstetrics and Gynaecology of Dhaka Medical College Hospital. Anaemic pregnant women supplemented with oral iron and amloki were considered as study group (A) and control group (B) were with only iron supplementation for 45 days. Serum zinc level was estimated in the laboratory of the Department of Soil, Water and Environment, University of Dhaka, Bangladesh.  For statistical analysis, Paired Student’s‘t’ test and Unpaired Student’s‘t’ test were considered using SPSS 22.0 version. Significant decrease (p<0.001) of serum zinc level was observed after intervention of iron in both groups. In this study, there was no significant difference in serum zinc level in between study and control group. It can be concluded that oral iron supplementation causes decrease in serum zinc level in IDA with pregnancy. Amloki shows no significant role in preventing decrease of serum zinc level in this study.  Emblicaofficinalis (amloki) is traditionally used to treat iron deficiency anaemia. It can increase haemoglobin concentration and decrease side effects of iron supplementation. Bangladesh Med J. 2020 Jan; 49 (1): 33-37

scholarly journals Study on serum zinc and copper levels in pulmonary tuberculosis patients before starting Directly Observed Treatment, Short-course

Mediscope ◽  
2021 ◽  
Vol 8 (2) ◽  
pp. 122-127
Author(s):  
Prithwy Shankar Biswas ◽  
Abu Md Mayeenuddin Al Amin ◽  
Syed Didarul Haque
Keyword(s):  
Serum Zinc ◽  
Zinc Level ◽  
Serum Copper ◽  
Copper Level ◽  
Control Group ◽  
Case Group ◽  
Serum Zinc Level ◽  
Mean Values ◽  
Short Course ◽  
Directly Observed Treatment

Background: Tuberculosis is a major public health concern throughout the world including Bangladesh. The prevalence of tuberculosis (TB) is increasing day by day. Around one-third of world population is infected with M. tuberculosis. Still pulmonary tuberculosis (PTB) remains one of the important causes of mortality throughout the world with economic burden. Objective: To evaluate levels of the serum zinc and serum copper in smear positive PTB patients before starting Directly Observed Treatment, Short-course (DOTs) therapy. Methods: This was a cross-sectional type of observational study. A total of 100 subjects were included in this study. Among them 50 were smear positive PTB patients denoted as case group and 50 were apparently healthy individuals denoted as control group. Biochemical tests were carried out in the department of biochemistry of Mymensingh Medical College, Mymensingh. All the statistical analyses were performed by using SPSS version 21. Results were evaluated by using Student’s t-test. Results: After careful evaluation there was significant decrease in serum zinc level along with significant increase in serum copper level among the case group when compared with the control group. The mean values of serum zinc level were 93.96±10.04 μg/dl and 72.84±7.73 μg/dl in control and case group respectively. Serum zinc level decreased significantly (p <0.001) in PTB patients. The mean values of serum copper were 111.81±21.26 μg/dl and 125.99±27.93 μg/dl in control and case group respectively. There was significant (p <0.001) rise of serum copper level in PTB patients. Mediscope 2021;8(2): 122-127

scholarly journals Nutritional Assessment and Serum Zinc Level in Children with Acute Lymphoblastic Leukaemia

2017 ◽  
Vol 40 (1) ◽  
pp. 12-16 ◽  
Author(s):  
Akma Morshed ◽  
Ikram Soma ◽  
TR Choudhury ◽  
Shahnoor Islam ◽  
Md Salim ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukaemia ◽  
Lymphoblastic Leukaemia ◽  
Serum Zinc ◽  
Zinc Level ◽  
Control Group ◽  
Case Group ◽  
Z Score ◽  
Serum Zinc Level ◽  
The Mean ◽  
Height For Age

Background: Acute lymphoblastic leukaemia (ALL) is a common malignancy in children which may cause significant nutritional problem as well as micronutrient deficiency like zinc. These deficiencies ultimately affect the outcome of the patient.Objective: The present study was done to identify the relationship of height, weight and serum zinc with acute lymphocytic leukemia in pediatric patients.Methods: This observational study was carried out in the Department of Pediatric Haematology and Oncology, Dhaka Medical College Hospital, Dhaka over a period of one year from July 2013 to June 2014. All children ranging from 1-10 years with newly diagnosed acute lymphocytic leukaemia were enrolled as case. An equal number of healthy children of similar age and sex were also included as control. The outcome measures were weight for height (wasting) and height for age (stunting) in children 5 or below 5 years of age and BMI in children > 5 years of age. The serum zinc level was also studied as a measure of micronutrient status.Result: Majority (80%) of the cases and 60% of the controls were 5 or < 5 years old. The mean ages of the children of cases and controls were almost similar (4.2 ± 2.3 vs. 4.8 ± 1.8 years, p >0.05). The groups were significantly different in terms of sex with male children being more prone to develop leukaemia than the females (p <0.05). Anaemia was invariably present. Majority (83.3%) of the children in the case group was wasted (weight for height Z-score lie below -2SD) as opposed 22.2% in the control group (p < 0.001). About 37% the children in the case group were stunted (height for age Z-score lies -2SD) as opposed to 16.7% in the control group (p< 0.05). The mean BMI was significantly lower in the case group than that in the control group (8.8 ± 2.7 vs. 17.1 ± 1.8, p < 0.001). Serum zinc level was also significantly lower in the former group than that in the latter group (0.7 ± 0.1 vs. 1.5 ± 0.5 mg/dl, p< 0.05).Conclusion: A good number leukaemia patients present with wasting and stunting and low BMI. Serum zinc level is significantly reduced which, in turn, may hamper various enzymatic functions in the body thereby reducing growth.Bangladesh J Child Health 2016; VOL 40 (1) :12-16

scholarly journals Leptin and Ghrelin in Excessive Gestational Weight Gain—Association between Mothers and Offspring

2019 ◽  
Vol 20 (10) ◽  
pp. 2398 ◽  
Author(s):  
Jolanta Patro-Małysza ◽  
Marcin Trojnar ◽  
Katarzyna E. Skórzyńska-Dziduszko ◽  
Żaneta Kimber-Trojnar ◽  
Dorota Darmochwał-Kolarz ◽  
...  
Keyword(s):  
Weight Gain ◽  
Birth Weight ◽  
Gestational Weight Gain ◽  
Body Length ◽  
Head Circumference ◽  
Maternal Serum ◽  
Control Group ◽  
Gestational Weight ◽  
Neonatal Birth Weight ◽  
Serum Ghrelin

Two-thirds of pregnant women exceed gestational weight gain recommendations. Excessive gestational weight gain (EGWG) appears to be associated with offspring’s complications induced by mechanisms that are still unclear. The aim of this study was to investigate whether umbilical cord leptin (UCL) and ghrelin (UCG) concentrations are altered in full-term neonates born to EGWG mothers and whether neonatal anthropometric measurements correlate with UCL and UCG levels and maternal serum ghrelin and leptin as well as urine ghrelin concentrations. The study subjects were divided into two groups, 28 healthy controls and 38 patients with EGWG. Lower UCL and UCG levels were observed in neonates born to healthy mothers but only in male newborns. In the control group UCG concentrations correlated positively with neonatal birth weight, body length and head circumference. In the control group maternal serum ghrelin levels correlated negatively with neonatal birth weight, body length and head circumference as well as positively with chest circumference. In the EGWG group UCG concentrations correlated negatively with neonatal birth weight and birth body length. UCL correlated positively with birth body length in EGWG group and negatively with head circumference in the control group. In conclusion, EGWG is associated with disturbances in UCL and UCG concentrations.

scholarly journals Association of Serum Zinc Level with Febrile Seizures in Children

2021 ◽  
pp. 200-203
Author(s):  
Maryum Naveed ◽  
Rimsha Mohsin ◽  
Palwasha Khan
Keyword(s):  
Febrile Seizure ◽  
Serum Zinc ◽  
Febrile Convulsion ◽  
Febrile Seizures ◽  
Cross Sectional Study ◽  
Zinc Level ◽  
Control Group ◽  
Case Group ◽  
Serum Zinc Level ◽  
Cross Sectional

Introduction: Febrile seizure (FS), previously known as febrile convulsion, is the most common seizure in children. FS usually occurs between six months and five years of age. Aims and objectives: The main objective of the study is to find the association of serum zinc level with febrile seizures in children of Pakistan. Material and methods: This cross sectional study was conducted at Mayo Hospital, Lahore during June 2020 to January 2021. The data was collected from 164 patients of both genders. Results: The data was collected from 164 patients. In the case group, 46 children were male (53.3%), and 36 children (46.7%) were female. In the control group 44 children were male (43.3%) and 38 children were female (56.7%). The age of all participants was between one months and six years. Conclusion: It is concluded that low serum zinc levels are fairly un-sufficient to support the hypothesis that Zinc deficiency could not be a potential risk factor for febrile seizure in children.

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