scholarly journals Effects of Iron and Amloki (EmblicaOfficinalis) on Serum Zinc Level in Anaemia with Pregnancy

2021 ◽  
Vol 49 (1) ◽  
pp. 33-37
Author(s):  
Tahmina Akter ◽  
Qazi Shamima Akther ◽  
Saima Haque Lisa ◽  
Mst Ariza Sultana ◽  
Farhana Sultana ◽  
...  
Keyword(s):  
Side Effects ◽  
Iron Deficiency Anaemia ◽  
Iron Supplementation ◽  
Serum Zinc ◽  
Zinc Level ◽  
Control Group ◽  
Serum Zinc Level ◽  
Deficiency Anaemia ◽  
Medical College ◽  
And Control

Pregnancy is associated with several trace elements deficiency in developing countries. Supplementation of iron in iron deficiency anaemia (IDA) has several side effects including alterations of serum zinc level. Traditionally, amloki is used as a well known supplement in pregnancy, which is rich in trace elements.To determine the effects of iron and amloki on serum zinc level in IDA with pregnancy. The study was a non blind, non random sampling interventional type of clinical trial. This study was performed in the Department of Physiology, Dhaka Medical College, Dhaka on 43 pregnant women between 13th to 20th weeks of gestation with IDA from July 2016 to June 2017.  They were recruited from Outpatient Department of Obstetrics and Gynaecology of Dhaka Medical College Hospital. Anaemic pregnant women supplemented with oral iron and amloki were considered as study group (A) and control group (B) were with only iron supplementation for 45 days. Serum zinc level was estimated in the laboratory of the Department of Soil, Water and Environment, University of Dhaka, Bangladesh.  For statistical analysis, Paired Student’s‘t’ test and Unpaired Student’s‘t’ test were considered using SPSS 22.0 version. Significant decrease (p<0.001) of serum zinc level was observed after intervention of iron in both groups. In this study, there was no significant difference in serum zinc level in between study and control group. It can be concluded that oral iron supplementation causes decrease in serum zinc level in IDA with pregnancy. Amloki shows no significant role in preventing decrease of serum zinc level in this study.  Emblicaofficinalis (amloki) is traditionally used to treat iron deficiency anaemia. It can increase haemoglobin concentration and decrease side effects of iron supplementation. Bangladesh Med J. 2020 Jan; 49 (1): 33-37

scholarly journals Effects of Iron and Amloki (Emblica Officinalis) on Serum Zinc Level in Anaemia with Pregnancy

2021 ◽  
Vol 33 (1) ◽  
pp. 61-64
Author(s):  
Tahmina Akter ◽  
Qazi Shamima Akther ◽  
Saima Haque Lisa ◽  
Mst Ariza Sultana ◽  
Sunjida Akter Suma ◽  
...  
Keyword(s):  
Trace Elements ◽  
Iron Supplementation ◽  
Serum Zinc ◽  
Zinc Level ◽  
Control Group ◽  
Serum Zinc Level ◽  
Medical College ◽  
Student’S T ◽  
And Control ◽  
Student’S T Test

Introduction: Pregnancy is associated with several trace elements deficiency in developing countries. Supplementation of iron in iron deficiency anaemia (IDA) has several side effects including alterations of serum zinc level. Traditionally, amloki is used as a well known supplement in pregnancy, which is rich in trace elements. Aims were to determine the effects of iron and amloki on serum zinc level in IDA with pregnancy. Materials and Methods: This Prospective, longitudinal and interventional study was done by non blinded, non randomized sampling followed by inclusion and exclusion criteria. This study was performed in the Department of Physiology, Dhaka Medical College, Dhaka on 43 pregnant women between 13th to 20th weeks of gestation with IDA from July 2016 to June 2017. They were recruited from Outpatient Department of Obstetrics and Gynaecology of Dhaka Medical College Hospital. Anaemic pregnant women supplemented with oral iron and amloki were considered as study group (A) and control group (B) were with only iron supplementation for 45 days. Serum zinc level was estimated in the laboratory of the Department of Soil, Water and Environment, University of Dhaka, Dhaka. For statistical analysis, Paired Student’s ‘t’ test and Unpaired Student’s ‘t’ test were considered using SPSS 22.0 version. Results: Significant decrease (p<0.001) of serum zinc level was observed after intervention of iron in both groups. In this study, there was no significant difference in serum zinc level in between study and control group. Conclusion: It can be concluded that oral iron supplementation causes decrease in serum zinc level in IDA with pregnancy. Amloki shows no significant role in preventing decrease of serum zinc level in this study. Medicine Today 2021 Vol.33(1): 61-64

scholarly journals ROLE OF SERUM ZINC LEVEL IN CHILDREN WITH FEBRILE CONVULSIONS

2019 ◽  
Vol 3 (9) ◽  
Author(s):  
Dr. Laxminarayan Nagal ◽  
Dr Jagdish Dabi ◽  
Dr. Harish Kumar Mourya
Keyword(s):  
Febrile Seizure ◽  
Tertiary Care ◽  
Serum Zinc ◽  
Zinc Level ◽  
Control Group ◽  
Serum Zinc Level ◽  
Tertiary Care Centre ◽  
Febrile Convulsions ◽  
Zinc Levels ◽  
And Control

Background: The aim of the present study was to determine whether there were any changes in serum zinc level in children with febrile seizure in comparison with febrile children without seizure. Methods: A prospective observational study was done on 100 children, admitted in a tertiary care centre. Of these 50 children were diagnosed to have febrile convulsions. The other 50 were febrile children without seizures. Serum zinc levels were measured in all 100 subjects using calorimetric methods. Data was analyzed using SPSS version 22. Results: In present study, we studied 50 children (36 males, 14 females) with febrile seizure and a control group of 50 patients (37 male, 13 female). The mean ages of patients in the febrile seizure and control group were 25.01±14.07 months and 26.07±13.6 months, respectively. Mean zinc level was 69.78±13.13mcg/dl and 80.72±10.21 mcg/dl in study and control groups respectively and this difference was found statistically highly significant (p<0.001). Conclusion: Our findings revealed that serum zinc level was significantly lower in children with febrile seizure in comparison with children without seizure. Keywords: febrile seizure, children, epilepsy.

scholarly journals Growth Status and Serum Zinc Level in Patients with Haemoglobin –E-? Thalassemia

2012 ◽  
Vol 36 (2) ◽  
pp. 76-81
Author(s):  
AKM Amirul Morshed ◽  
Shahnoor Islam ◽  
Afiqul Islam
Keyword(s):  
Serum Zinc ◽  
Zinc Level ◽  
Control Group ◽  
Healthy Children ◽  
Serum Zinc Level ◽  
Blood Samples ◽  
Growth Status ◽  
Significant Difference ◽  
Hb E ◽  
And Control

Background: Hb- E - ? thalassemia is a major congenital hematological disease of Bangladesh. These patients have poor growth and delayed maturation mainly due to iron overload but zinc deficiency also has been suggested as a contributing factor. Objectives: To investigate and compare the serum zinc of Hb E ? thalassemia patients and normal children and to see the relationship between serum zinc and growth status. Methods: This cross sectional study on Hb –E ? thalassemia was under taken in the out patient department of Paediatric Haematology and Oncology department of Bangabandhu Sheikh Mujib Medical University from July 2009- May 2010. Total 31 children with Hb- E- ? thalassemia were enrolled for this study and matched 30 healthy children were taken as control. History of the cases were taken thoroughly and examination were done by the investigator himself. Anthropometry were measured properly and plotted in Centre for Disease Control (CDC) chart. Three ml (3 ml) of venous blood samples were drawn from both patient and control. Later on the blood samples were centrifuged and serum was stored at – 20c till analysis for serum sinc level. Serum level of zinc was measured by using Flame Atomic Absorption Spectrophotometry following standard proceduve. Results: Mean serum zinc level in thalassemic group and control group were 97.4?g/dl (SD-18.4) and 99.6?g/dl (SD-18.7) respectively. There was no significant difference between two groups (p=.47). Mean percent of 50th centile of weight achieved was 75.9% in cases and 81% in control. Similarly mean percent of 50th centile of height achieved was 89% in cases and 93% in control. There was significant difference in height for age between both the groups (p=.05). Conclusion: Serum zinc level did not significantly changed in thalassemic group and control group children. But there were significant stunting in Hb –E ? thalassemia patients and no significant difference was found between these children in terms of weight for age. DOI: http://dx.doi.org/10.3329/bjch.v36i2.13083 Bangladesh J Child Health 2012; Vol 36 (2): 76-81

scholarly journals A study to assess the effectiveness of honey dates amla mix on biochemical markers among adolescent girls with Iron deficiency anaemia

2020 ◽  
Vol 11 (2) ◽  
pp. 2288-2293
Author(s):  
Bhuvaneswari G.
Keyword(s):  
Iron Deficiency ◽  
Adolescent Girls ◽  
Biochemical Markers ◽  
Serum Iron ◽  
Iron Deficiency Anaemia ◽  
Control Group ◽  
Deficiency Anaemia ◽  
Post Test ◽  
And Control ◽  
Experimental Group

WHO Global Database on Anaemia for 1993-2005, covering almost half of the world’s population, estimated the prevalence of anaemia worldwide at 25 per cent.The aim of the study is to determine the effectiveness of honey dates amla mix on biochemical markers among adolescent girls with Iron deficiency anaemia. Quantitative experimental and control group pre and post-test design was used in this study. The study was conducted among adolescent girls in two different residential homes. Total study population is 170 adolescent girls were selected by simple random sampling technique. 85 adolescents girls were assigned to the experimental group and 85 participants in control group. For experimental group honey dates amla mix was given for 3 months whereas in  the control group iron and folic acid supplementation were provided. The study results shows that pre and post-test intervention scores of control and experimental group were compared by Wilcoxon scores rank test. Comparison of pre-test and post-test scores of severity of anemia, clinical variables, and level of fatigue and level of satisfaction, bio chemical parameters (reticulocytes, MCV, haematocrite, serum iron, serum ferritin, TIBC) were assessed in both experimental and control group. Between the experimental and control group (unpaired‘t’ test) reticulocytes, mcv, heamatocrite, serum iron serum ferritin showed significant changes in the pre test and post-test but there is no changes in TIBC. The study concluded that alternative nutritional therapy was effective for enhancing the blood heamoglobin & biochemical paramteres level, decreased the clinical variables and fatigue level among the adolescent girls with iron deficiency anemia.

scholarly journals Study on serum zinc and copper levels in pulmonary tuberculosis patients before starting Directly Observed Treatment, Short-course

Mediscope ◽  
2021 ◽  
Vol 8 (2) ◽  
pp. 122-127
Author(s):  
Prithwy Shankar Biswas ◽  
Abu Md Mayeenuddin Al Amin ◽  
Syed Didarul Haque
Keyword(s):  
Serum Zinc ◽  
Zinc Level ◽  
Serum Copper ◽  
Copper Level ◽  
Control Group ◽  
Case Group ◽  
Serum Zinc Level ◽  
Mean Values ◽  
Short Course ◽  
Directly Observed Treatment

Background: Tuberculosis is a major public health concern throughout the world including Bangladesh. The prevalence of tuberculosis (TB) is increasing day by day. Around one-third of world population is infected with M. tuberculosis. Still pulmonary tuberculosis (PTB) remains one of the important causes of mortality throughout the world with economic burden. Objective: To evaluate levels of the serum zinc and serum copper in smear positive PTB patients before starting Directly Observed Treatment, Short-course (DOTs) therapy. Methods: This was a cross-sectional type of observational study. A total of 100 subjects were included in this study. Among them 50 were smear positive PTB patients denoted as case group and 50 were apparently healthy individuals denoted as control group. Biochemical tests were carried out in the department of biochemistry of Mymensingh Medical College, Mymensingh. All the statistical analyses were performed by using SPSS version 21. Results were evaluated by using Student’s t-test. Results: After careful evaluation there was significant decrease in serum zinc level along with significant increase in serum copper level among the case group when compared with the control group. The mean values of serum zinc level were 93.96±10.04 μg/dl and 72.84±7.73 μg/dl in control and case group respectively. Serum zinc level decreased significantly (p <0.001) in PTB patients. The mean values of serum copper were 111.81±21.26 μg/dl and 125.99±27.93 μg/dl in control and case group respectively. There was significant (p <0.001) rise of serum copper level in PTB patients. Mediscope 2021;8(2): 122-127

scholarly journals Nutritional Assessment and Serum Zinc Level in Children with Acute Lymphoblastic Leukaemia

2017 ◽  
Vol 40 (1) ◽  
pp. 12-16 ◽  
Author(s):  
Akma Morshed ◽  
Ikram Soma ◽  
TR Choudhury ◽  
Shahnoor Islam ◽  
Md Salim ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukaemia ◽  
Lymphoblastic Leukaemia ◽  
Serum Zinc ◽  
Zinc Level ◽  
Control Group ◽  
Case Group ◽  
Z Score ◽  
Serum Zinc Level ◽  
The Mean ◽  
Height For Age

Background: Acute lymphoblastic leukaemia (ALL) is a common malignancy in children which may cause significant nutritional problem as well as micronutrient deficiency like zinc. These deficiencies ultimately affect the outcome of the patient.Objective: The present study was done to identify the relationship of height, weight and serum zinc with acute lymphocytic leukemia in pediatric patients.Methods: This observational study was carried out in the Department of Pediatric Haematology and Oncology, Dhaka Medical College Hospital, Dhaka over a period of one year from July 2013 to June 2014. All children ranging from 1-10 years with newly diagnosed acute lymphocytic leukaemia were enrolled as case. An equal number of healthy children of similar age and sex were also included as control. The outcome measures were weight for height (wasting) and height for age (stunting) in children 5 or below 5 years of age and BMI in children > 5 years of age. The serum zinc level was also studied as a measure of micronutrient status.Result: Majority (80%) of the cases and 60% of the controls were 5 or < 5 years old. The mean ages of the children of cases and controls were almost similar (4.2 ± 2.3 vs. 4.8 ± 1.8 years, p >0.05). The groups were significantly different in terms of sex with male children being more prone to develop leukaemia than the females (p <0.05). Anaemia was invariably present. Majority (83.3%) of the children in the case group was wasted (weight for height Z-score lie below -2SD) as opposed 22.2% in the control group (p < 0.001). About 37% the children in the case group were stunted (height for age Z-score lies -2SD) as opposed to 16.7% in the control group (p< 0.05). The mean BMI was significantly lower in the case group than that in the control group (8.8 ± 2.7 vs. 17.1 ± 1.8, p < 0.001). Serum zinc level was also significantly lower in the former group than that in the latter group (0.7 ± 0.1 vs. 1.5 ± 0.5 mg/dl, p< 0.05).Conclusion: A good number leukaemia patients present with wasting and stunting and low BMI. Serum zinc level is significantly reduced which, in turn, may hamper various enzymatic functions in the body thereby reducing growth.Bangladesh J Child Health 2016; VOL 40 (1) :12-16

scholarly journals Comparison of birth weights of neonates of mothers receiving vs. not receiving zinc supplement at pregnancy

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hassan Boskabadi ◽  
Gholamali Maamouri ◽  
Javad Akhondian ◽  
Farah Ashrafzadeh ◽  
Abbas Boskabadi ◽  
...  
Keyword(s):  
Birth Weight ◽  
Essential Element ◽  
Serum Zinc ◽  
Zinc Level ◽  
Maternal Serum ◽  
Control Group ◽  
Serum Zinc Level ◽  
Zinc Supplement ◽  
Neonatal Birth Weight ◽  
Zinc Supplements

Abstract Background Zinc is an essential element for normal embryogenesis and embryonic and neonatal development. Therefore, we compared the birth weights of neonates born to mothers who consumed zinc supplement during pregnancy with that of neonates born to mothers who did not. Methods In a cross-sectional study, we divided 200 pregnant mothers into two groups: case group (mothers receiving zinc supplement during pregnancy) and control group (mothers not receiving zinc supplement during pregnancy) Then, the neonate’s cord zinc level and mother’s serum level were measured and neonate’s growth charts (weight, height and head circumference)were completed. Results In this study, both groups of mothers were observed to have zinc deficiency; 35% of the mothers who consumed zinc supplements and 81% of the mothers who did not consume zinc supplements (P < 0.001). Based on the results, maternal serum of zinc (P < 0.001), neonatal birth weight (P = 0.008), maternal age (P < 0.001) and parity (P < 0.01) in zinc-supplemented group were higher. Neonatal birth weight was associated moderately with mother’s zinc serum levels and poorly with neonatal serum zinc levels. Conclusion Zinc consumption during pregnancy increases serum zinc level of mother and neonatal weight. Neonatal weight has a higher correlation to maternal serum zinc level.

scholarly journals Association of Serum Zinc Level with Febrile Seizures in Children

2021 ◽  
pp. 200-203
Author(s):  
Maryum Naveed ◽  
Rimsha Mohsin ◽  
Palwasha Khan
Keyword(s):  
Febrile Seizure ◽  
Serum Zinc ◽  
Febrile Convulsion ◽  
Febrile Seizures ◽  
Cross Sectional Study ◽  
Zinc Level ◽  
Control Group ◽  
Case Group ◽  
Serum Zinc Level ◽  
Cross Sectional

Introduction: Febrile seizure (FS), previously known as febrile convulsion, is the most common seizure in children. FS usually occurs between six months and five years of age. Aims and objectives: The main objective of the study is to find the association of serum zinc level with febrile seizures in children of Pakistan. Material and methods: This cross sectional study was conducted at Mayo Hospital, Lahore during June 2020 to January 2021. The data was collected from 164 patients of both genders. Results: The data was collected from 164 patients. In the case group, 46 children were male (53.3%), and 36 children (46.7%) were female. In the control group 44 children were male (43.3%) and 38 children were female (56.7%). The age of all participants was between one months and six years. Conclusion: It is concluded that low serum zinc levels are fairly un-sufficient to support the hypothesis that Zinc deficiency could not be a potential risk factor for febrile seizure in children.

scholarly journals A Study of Serum Zinc level in Patients with Acute Myocardial Infarction

2021 ◽  
Vol 15 (2) ◽  
pp. 92-94
Author(s):  
Mohammad Rezaul Quader ◽  
Sharmin Rahman ◽  
Suranjit Kumar Saha
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Trace Element ◽  
Serum Zinc ◽  
Zinc Level ◽  
Mean Values ◽  
Medical College ◽  
Important Trace Element ◽  
The Mean ◽  
And Control

Acute myocardial infarction is one of the most important reason of death in the world. There are some established risk factors of acute myocardial infarction (AMI), but measurement of trace element like zinc can be helpful in the prevention and better management of AMI. The aim of this study was to estimate serum zinc in AMI patients. This is a case control type of study carried out in the Department of Biochemistry, Dhaka Medical College, Dhaka during the period of January 2015 to December 2015 with a total number of 100 study subjects. Acute myocardial infarction patients were selected as case (50) from coronary care unit (CCU), Department of Cardiology, Dhaka Medical College Hospital. Normal healthy individuals were selected as control (50) from the attendants of patients, relatives and doctors. Serum level of zinc was assessed for both case and control groups. The mean values of the variable were compared between them by statistical analysis using SPSS version 16. For all the statistical analysis p<0.05 was considered as significant. The mean values of serum zinc were 73.18±21.14μg/dl in cases. The mean values of serum zinc were 11.04±23.06 μg/dl in control group. Significant differences were found in mean values between case and control groups and differences were very highly significant (p-value<0.001). In AMI serum zinc levels were found to decrease in this study. Serum zinc is an important trace element act as cofactor in many biochemical reactions. Decrease level of this important trace element may contribute to pathogenesis of AMI. So with other biochemical risks parameters, routine assessment of serum zinc level is advocated, which might be helpful for prevention and better management of AMI. Faridpur Med. Coll. J. 2020;15(2): 92-94

scholarly journals Low Serum Zinc Level May be Related to Higher Doses of EPO in Hemodialysis Patients

2015 ◽  
Vol 12 (1) ◽  
pp. 40-44
Author(s):  
Itir Yegenaga ◽  
Zeki Aydin
Keyword(s):  
Serum Zinc ◽  
Zinc Level ◽  
Control Group ◽  
Inadequate Response ◽  
Recombinant Erythropoietin ◽  
Serum Zinc Level ◽  
Human Recombinant Erythropoietin ◽  
Zinc Levels ◽  
The Relationship ◽  
Serum Zinc Levels

AbstractIntroduction.Anemia is a complication of chronic renal failure observed in patients on hemodialysis (HD) affecting morbidity and mortality of these patients. It is associated with erythropoietin (EPO) deficiency and can be treated by human recombinant erythropoietin (hrEPO). Iron deficiency has been reported as the first line cause for inadequate response to this treatment. Zinc deficiency in hemodialysis (HD) patients was previously reported and the relationship between iron and zinc deficiencies has been known for years. The aim of this study was to find out the relationship between serum zinc level, anemia and rhEPO consuming in HD patients.Methods.A total of 69 HD patients and 34 healthy individuals were included in the study. Serum zinc levels, clinical, hematologic, biochemical parameters and rhEPO doses were evaluated.Results.Serum zinc levels were found to be lower in HD patients in comparison to those in the control group (29.92±12.94, 44.82±27.69μg/dL, respectively) (p<0.001). There was a positive correlation between serum zinc and hemoglobin (Hb) in the control group (R2=0.06). In HD patients who needed less then 8000U/week rhEPO, Hb levels (p<0.05) and serum zinc levels were higher. Serum zinc and Hb levels were found to be higher in patients who were under HD treatment for more than 12 months (10.05±1.06 vs 10.69±1.29; p=0.022 and 26.96±13.29 vs 30.88±12.61; p=0.178).Conclusions.HD patients who needed lower dose of EPO had higher serum zinc levels. Although the difference was not statistically significant, these results provide evidence that serum zinc level should be taken into consideration especially in HD patients resistant to EPO therapy.

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