scholarly journals Correlation between intraoperative and postoperative vaulting of the EVO implantable Collamer lens: a retrospective study of real-time observations of vaulting using the RESCAN 700 system

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Nian Guan ◽  
Xiao-Nong Zhang ◽  
Wan-Jun Zhang
Keyword(s):  
Retrospective Study ◽  
Anterior Chamber ◽  
Multivariable Analysis ◽  
Anterior Chamber Depth ◽  
Crystalline Lens ◽  
Implantable Collamer Lens ◽  
Chamber Volume ◽  
Anterior Chamber Volume ◽  
Intraoperative Optical Coherence Tomography ◽  
Corneal Endothelial Cell Density

Abstract Background Implantable Collamer lens (ICL) vaulting is one of the most important parameters for the safety, aqueous humor circulation, and lens transparency after ICL implantation. This study aimed to investigate the factors associated with the actual vaulting after refractive EVO-ICL surgery. Methods This retrospective study included patients who underwent EVO-ICL surgery at a tertiary eye hospital between October and December 2019. A RESCAN 700 was used for the intraoperative and CIRRUS HD-OCT was used for postoperative observation of vaulting. Subjective and objective refractions, anterior ocular segment, corneal morphology, intraocular pressure (IOP), anterior chamber volume (ACV), crystalline lens rise (CLR), white-to-white distance (WTW), anterior chamber depth (ACD), axial length, corneal endothelial cell density (ECD), and fundoscopy were examined. A multivariable analysis was performed to determine the factors independently associated with 1-month postoperative vaulting. Results Fifty-one patients (102 eyes) were included. Compared with the eyes with normal vaulting, those with high vaulting had higher preoperative diopter values (P = 0.039), lower preoperative corrected visual acuity (P = 0.006), lower preoperative IOP (P = 0.029), higher preoperative ACD (P = 0.004), lower preoperative CLR (P = 0.046), higher ICL spherical equivalent (P = 0.030), higher intraoperative vaulting (P < 0.001), and lower IOP at 1 month (P = 0.045). The multivariable analysis showed that the only factor independently associated with high vaulting at 1 month after surgery was the intraoperative vaulting value (odds ratio = 1.005, 95% confidence interval: 1.002–1.007, P < 0.001). The intraoperative and 1-month postoperative vaulting values were positively correlated (R2 = 0.562). Conclusions The RESCAN700 system can be used to perform intraoperative optical coherence tomography to predict the vaulting value of ICL at 1 month.

scholarly journals Correlation between vaulting intraoperative and postoperative of EVO implantable Collamer lens: a retrospective study of real-time observations of vaulting using the RESCAN 700 system

2020 ◽  
Author(s):  
Nian Guan ◽  
Xiao-Nong Zhang ◽  
Wan-Jun Zhang
Keyword(s):  
Optical Coherence Tomography ◽  
Intraocular Pressure ◽  
Retrospective Study ◽  
Multivariable Analysis ◽  
Anterior Chamber Depth ◽  
Crystalline Lens ◽  
Optical Coherence ◽  
Implantable Collamer Lens ◽  
Corrected Visual Acuity ◽  
Intraoperative Optical Coherence Tomography

Abstract Background: The prediction of implantable Collamer lens (ICL) vaulting is one of the most important parameters for ICL implantation for safety, aqueous humor circulation, and lens transparency.Methods: This was a retrospective study. A RESCAN 700 was used for intraoperative observation of vaulting. Spectral-domain optical coherence tomography was used for imaging. Results: Finally, 51 patients (102 eyes) were included in the study. Compared with the eyes with normal vaulting, those with high vaulting had higher preoperative diopter values (P=0.039), lower preoperative corrected visual acuity (P=0.006), lower preoperative intraocular pressure (P=0.029), higher preoperative anterior chamber depth (P=0.004), lower preoperative crystalline lens rise (P=0.046), higher ICL spherical equivalent (P=0.030), higher intraoperative vaulting (P<0.001), and lower intraocular pressure at 1 month (P=0.045). The multivariable analysis showed that the only factors independently associated with high vaulting at 1 month after surgery was the intraoperative vaulting value (odds ratio=1.005, 95% confidence interval: 1.002-1.007, P<0.001). The intraoperative and 1-month postoperative vaulting values were correlated (R2=0.562).Conclusions: The RESCAN700 system can be used to perform intraoperative optical coherence tomography to predict the vaulting value at 1 month.

scholarly journals Two-Year Outcomes of Visian Implantable Collamer Lens with a Central Hole for Correcting High Myopia

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Zhipeng Yan ◽  
Huamao Miao ◽  
Feng Zhao ◽  
Xiaoying Wang ◽  
Xun Chen ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Anterior Chamber ◽  
High Myopia ◽  
Imaging System ◽  
Anterior Chamber Depth ◽  
Central Hole ◽  
Implantable Collamer Lens ◽  
Chamber Volume ◽  
Anterior Chamber Volume ◽  
Icl V4c

Purpose. To investigate two-year outcomes of Visian Implantable Collamer Lens with a central hole (ICL V4c) implantation for correcting high myopia.Methods. Sixty-one eyes of 32 patients went through ICL V4c implantation. Safety, efficacy, predictability, and intraocular pressure were evaluated 2 years postoperatively. Anterior chamber volume (ACV), anterior chamber depth (ACD), anterior chamber angle width (ACAW), and vault were measured using a Scheimpflug tomography imaging system.Results. At 2 years, the spherical equivalent refraction decreased from preoperative −14.62 ± 4.29 D to −0.90 ± 0.95 D, with 79% of the eyes within ±0.50 D and 98% within ±1.00 D of the intended correction. The efficacy index was 1.03 ± 0.23, and the safety index was 1.24 ± 0.26. Corrected distance visual acuity (CDVA) remained unchanged in 23% of the eyes, 75% gained one or more lines of CDVA, and 2% lost one line. The ACV, ACD, and ACAW, respectively, decreased from 193.28 ± 29.15 mm3, 3.15 ± 0.23 mm, and 36.51 ± 6.54 degree to 112.48 ± 17.01 mm3, 2.99 ± 0.23 mm, and 22.54 ± 5.27 degree (p=0.0008,  0.008,  and  0.0003, resp.). Intraocular pressure was 15.39 ± 2.88 mmHg before surgery and was 15.86 ± 4.11 mmHg at 2 years (p=0.11).Conclusion. Implantation of ICL V4c is a safe, effective, and predictable procedure for correcting high myopia. Reduction of anterior chamber space after surgery did not induce intraocular pressure increase during the 2-year follow-up.

scholarly journals Prediction of anterior chamber volume after implantation of posterior chamber phakic intraocular lens

PLoS ONE ◽  
2020 ◽  
Vol 15 (11) ◽  
pp. e0242434
Author(s):  
Yuki Takagi ◽  
Takashi Kojima ◽  
Tomoya Nishida ◽  
Tomoaki Nakamura ◽  
Kazuo Ichikawa
Keyword(s):  
Anterior Chamber ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Absolute Error ◽  
Prediction Equation ◽  
Stepwise Multiple Regression ◽  
Posterior Chamber ◽  
Implantable Collamer Lens ◽  
Chamber Volume ◽  
Anterior Chamber Volume

Purpose To predict the anterior chamber volume (ACV) after implantable collamer lens (ICL) implantation based on ICL size and parameters of anterior segment optical coherence tomography (AS-OCT). Design Retrospective study. Methods This study included 222 eyes of 222 patients who underwent ICL implantation at Nagoya Eye Clinic. The patients were divided into two groups: prediction group, for creating the prediction equation (148 eyes, mean age: 32.11 ± 8.04 years), and verification group, for verifying the equation (74 eyes, mean age: 33.03 ± 6.74 years). The angle opening distance (AOD), anterior chamber width (ACW), ACV, anterior chamber depth, lens vault, angle-to-angle distance, angle recess area, and trabecular iris space area were calculated using AS-OCT. A stepwise multiple regression analysis was performed. After the creation of the prediction equation, its accuracy was verified in the verification group. Results The ACV, AOD750, ACW, and ICL size were selected as explanatory variables to predict postoperative ACV. Mean predicted (114.2 ± 21.83 mm3) and actual postoperative ACVs (116.1 ± 25.41 mm3) were not significantly different (P = 0.269); absolute error was 10.59 ± 9.13 mm3. In addition, there was high correlation between actual and predictive ACV (adjusted R2 = 0.6996, p < 0.0001). Bland-Altman plot revealed that there was no addition or proportional error between predicted and actual postoperative ACV. Conclusion Postoperative ACV was accurately predicted using AS-OCT parameters and ICL size. This prediction equation may be useful for making decisions regarding ICL size.

scholarly journals Changes in Anterior Segment Morphology of Iris Bombe before and after Laser Peripheral Iridotomy in Patients with Uveitic Secondary Glaucoma

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Wakako Ikegawa ◽  
Takashi Suzuki ◽  
Koji Namiguchi ◽  
Shiro Mizoue ◽  
Atsushi Shiraishi ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Anterior Chamber Angle ◽  
Laser Peripheral Iridotomy ◽  
Chamber Volume ◽  
Anterior Chamber Volume ◽  
Before And After ◽  
The Mean ◽  
Peripheral Iridotomy

Purpose. To quantify changes in anterior segment (AS) parameters after laser peripheral iridotomy (LPI) using AS-optical coherence tomography (OCT) of iris bombe. Method. AS images of eight eyes were captured before and after iris bombe and more than 2 weeks after LPI (post-LPI) using AS-OCT. We compared the following AS parameters: anterior chamber depth (ACD), anterior chamber volume (ACV), iris curvature (IC), iris thickness at 500 μm from the scleral spur (IT-1) in the middle between the iris root and pupillary margin (IT-2) and 500 μm from the pupillary margin (IT-3) to the anterior chamber angle (ACA) (angle opening distance [AOD750]), and trabecular iris space area. Results. Mean IT-1 and IT-3, but not IT-2, were lower after iris bombe (IT-1, P=0.001; IT-2, P=0.081; and IT-3, P=0.001). There were no significant differences between ACD at pre-LPI and before iris bombe (P=0.096). The mean ACV and AOD750 of iris bombe increased at post-LPI (ACV, P<0.01, and AOD750, P<0.05). The mean IT-1, IT-2, and IT-3 increased at post-LPI (all, P≤0.01). IC decreased at post-LPI (P<0.001), and ACD at post-LPI did not change. Conclusions. The iris extends and becomes thinner during iris bombe. LPI during bombe decreases the IC and increases the ACV and ACA.

Association of anterior segment parameters and 5-year incident narrow angles: findings from an older Chinese population

2020 ◽  
pp. bjophthalmol-2020-315852
Author(s):  
Yu Jiang ◽  
Wei Wang ◽  
Lanhua Wang ◽  
Mingguang He
Keyword(s):  
Anterior Chamber ◽  
Multiple Logistic Regression Analysis ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Narrow Angle ◽  
Chamber Volume ◽  
Anterior Chamber Volume ◽  
Oct Imaging ◽  
Older Chinese ◽  
Analysis Models

PurposeTo assess the association of anterior segment optical coherence tomography (AS-OCT) parameters and 5-year incident narrow angle in China.MethodsThis was a prospective cohort study of people aged 50 and older residing in Liwan District, Guangzhou, China. Random clustering sampling was used to identify adults aged 50 years and older in Liwan District, Guangzhou. In 2008 and 2013, this study was repeated and added AS-OCT imaging under dark and light conditions. Customised software (ZAAP) was used to analyse horizontal AS-OCT scans. Angle opening distance (AOD), trabecular iris space area (TISA), anterior chamber volume (ACV) and maximal iris thickness (ITM) were measured. Multiple logistic regression analysis models were used to investigate the associations of the final angle status with baseline AS-OCT parameters. ORs and 95% CIs were calculated.ResultsOf the 220 subjects with eligible AS-OCT images and gonioscopic results in 2008, the response rate was 77.3%. A total of 27 (15.9%) subjects developed narrow angles and 143 (84.1%) had open angles on gonioscopy in 2013. Subjects developed narrow angles had greater spherical equivalent and shallower anterior chamber depth, smaller angle parameters, thicker IT750 and ITM, smaller anterior chamber parameters, greater lens vault, and smaller dynamic parameters (ΔITM, ΔACA, ΔACV) at baseline. After adjusting confounders, the predictors of incident narrow angles included smaller AOD750, TISA750, ΔACA and greater ITM, ΔIarea.ConclusionsIncident narrow angles were associated with smaller anterior ocular dimensions, thicker iris and smaller light-to-dark changes at baseline. These findings can help in early diagnosis in this population.

scholarly journals Pupil Size Associated with the Largest Iris Volume in Normal Chinese Eyes

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Shuning Li ◽  
Jing Jiang ◽  
Yiquan Yang ◽  
Gewei Wu ◽  
Shi-Ming Li ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Pupil Size ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Quadratic Equation ◽  
Swept Source ◽  
Chamber Volume ◽  
Anterior Chamber Volume ◽  
The Relationship ◽  
Pupillary Size

Background. To determine the range of pupil size that has the largest iris volume in normal eyes. Methods. 31 healthy adult Chinese volunteers underwent swept-source anterior segment OCT examination in both eyes. Pilocarpine 1% was instilled in a randomly selected eye (eye with induced miosis (ME)) of each participant to obtain iris volume (IV) measurements over a range of pupil sizes. OCT was performed prior to and one hour after pilocarpine in both ME and fellow eye (FE). Iris volume (IV), anterior chamber volume (ACV), anterior chamber depth (ACD), and pupil size (PS) were recorded. A scatter plot was used to depict the association between each pupil size and IV. Results. The pupillary sizes for which IV was recorded in ME and FE ranged from 1.161 mm to 6.665 mm. The mean IV increased with miosis in both ME and FE; in 13 eyes, IV decreased with a decrease in pupillary size. PS between 3.812 and 6.665 mm was associated with an increase in IV, while PS between 3.159 and 5.54 mm was associated with a decrease. The relationship between PS and IV was in the shape of a downward parabola and was modeled using a quadratic equation (y = −1.3121x2 + 8.8429x + 16.423, R2 = 0.26886). The largest IV occurred at PS between 3 and 4 mm. Conclusions. The relationship between PS and IV in this study was in the shape of a downward parabola. The largest IV was recorded at a pupillary size between 3 and 4 mm. This trial is registered with ChiCTR-ROC-17013572.

Ocular biometric changes after Ahmed glaucoma valve implantation

2019 ◽  
pp. 112067211988952
Author(s):  
Arezoo Miraftabi ◽  
Mahboubeh Lotfi ◽  
Naveed Nilforushan ◽  
Parya Abdolalizadeh ◽  
Samira Jafari
Keyword(s):  
Anterior Chamber ◽  
Axial Length ◽  
Anterior Chamber Depth ◽  
Ahmed Glaucoma Valve ◽  
Anterior Chamber Angle ◽  
Chamber Volume ◽  
Anterior Chamber Volume ◽  
Valve Implantation ◽  
Ahmed Glaucoma Valve Implantation ◽  
Chamber Angle

Purpose: To investigate the ocular biometric changes after uneventful Ahmed glaucoma valve implantation. Methods: Patients with refractory glaucoma who were candidate for Ahmed valve surgery were prospectively included in this study. Patients with a history of any kinds of corneal surgery were excluded. Refractive status, intraocular pressure, axial length, anterior chamber parameters including anterior and posterior mean keratometry, central corneal thicknesses, and anterior chamber depth, anterior chamber volume, and anterior chamber angle were evaluated at baseline and 1 and 3 months after surgery. Results: A total of 20 eyes from 20 patients were included. Mean intraocular pressure at baseline was 33.4 ± 12.3 mm Hg that significantly decreased to 14.6 ± 6.2 mm Hg at 1 month and 13.5 ± 4.3 mm Hg at 3 months after Ahmed glaucoma valve implantation ( p < 0.001). Mean number of medications was 3.6 ± 1.3 at baseline which significantly decreased to 1.0 ± 1.3 at 3 months after Ahmed glaucoma valve implantation ( p < 0.001). Axial length decreased significantly from 23.69 ± 1.95 to 23.47 ± 1.91 mm ( p < 0.001) at month 3. There were no significant changes in other parameters such as mean spherical equivalent, anterior chamber volume, anterior chamber angle, anterior chamber depth, and keratometry at the end of month 3 after surgery ( p > 0.05 in all). Conclusion: Ahmed glaucoma valve implantation had a significant effect on axial length at 3 months after surgery but its effect on keratometry and other anterior chamber parameters was not significant.

scholarly journals Measurement of and Factors Associated with the Anterior Chamber Volume in Healthy Chinese Adults

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Yuan Zong ◽  
Qian Xu ◽  
Chunhui Jiang ◽  
Haohao Zhu ◽  
Jian Yu ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Chinese Adults ◽  
Factors Associated ◽  
Chamber Volume ◽  
Significant Difference ◽  
Anterior Chamber Volume ◽  
Anterior Segment Parameters ◽  
Healthy Chinese

Purpose. To measure the anterior chamber volume (ACV) and determine factors associated with the ACV in healthy Chinese adults.Methods. In this cross-sectional study, we used swept-source optical coherence tomography (SS-OCT) to measure ACV and other anterior segment parameters. Factors associated with ACV were also determined.Results. A total of 313 healthy Chinese adults were enrolled. The anterior segment parameters, including ACV, could be measured by SS-OCT with excellent repeatability and reproducibility. There was a significant difference between the horizontal and vertical anterior chamber widths (ACW) (P<0.05), with a mean difference of 390 μm. The ACV (mean153.83±32.42 mm3) was correlated with most of the anterior segment parameters, especially anterior chamber depth (ACD), which accounted for about 85% of the variation of ACV. Most of the anterior segment parameters were significantly correlated with age, and the relative changes in ACV and ACD were greatest in subjects aged 41–50 years.Conclusion. ACV was correlated with most of the anterior segment parameters measured in this study, particularly ACD. The relatively large difference between horizontal and vertical ACW suggests that the ACV could and should be measured using multiple OCT scans.

scholarly journals Potential of the Pentacam in Screening for Narrow Angles in Patients with Chronic Angle-Closure Glaucoma

2021 ◽  
Vol 18 (1) ◽  
pp. 39-44
Author(s):  
Seth Lartey ◽  
Abdul-Kabir Mohammed ◽  
Emmanuel Appiagyei ◽  
Kojo Akuffo
Keyword(s):  
Anterior Chamber ◽  
Anterior Chamber Depth ◽  
Area Under The Curve ◽  
Angle Closure Glaucoma ◽  
Receiver Operating Curve ◽  
Angle Closure ◽  
Effective Management ◽  
Narrow Angle ◽  
Chamber Volume ◽  
Anterior Chamber Volume

Background: Chronic angle-closure glaucoma (CACG) is a visually destructive disease. Effective management of CACG requires identifying eyes with narrow angle. Objective: To compare pentacam with gonioscopy in detecting narrow angles in eyes with CACG. Method: We enrolled 101 eyes with glaucoma. Gonioscopy was performed on all eyes. Using Shaffer’s grading, subjects were classified into angle closure and open angle. Anterior chamber volume (ACV) and anterior chamber depth (ACD) were measured with the pentacam. Receiver operating curve was constructed for each parameter and the area under the curve (AUC) was calculated. Results: Ten eyes (9.9%) were classified as angle closure on gonioscopy. To detect narrow angles, ACV (AUC 0.956; 95% confidence interval (CI) 0.894–0.987) performed similar to ACD (AUC=0.930, p=0.33). Using a cutoff of 102 mm3 , ACV had 100% sensitivity and 88.5% specificity for detecting narrow angles in CACG patients. With an ACV cutoff of 102 mm3 , the PPV for detecting angle closure was 48.9% (95% CI, 34.8–68.2), while the NPV was 100% (94.1– 100%), using 9.9% prevalence of angle closure from this study. Conclusion: ACV and ACD measured by the pentacam have the potential to determine narrow angles in eyes with CACG. Keywords: Chronic angle-closure glaucoma, Pentacam HR, Anterior chamber volume, Gonioscopy

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