scholarly journals Screening of vitamin D and calcium concentrations in neonates of mothers at high risk of vitamin D deficiency

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Sheikh Arif M. Kozgar ◽  
Paul Chay ◽  
Craig F. Munns
Keyword(s):  
Vitamin D ◽  
High Risk ◽  
Vitamin D Deficiency

scholarly journals Vitamin D and Cardiovascular Disease: An Updated Narrative Review

2021 ◽  
Vol 22 (6) ◽  
pp. 2896
Author(s):  
Armin Zittermann ◽  
Christian Trummer ◽  
Verena Theiler-Schwetz ◽  
Elisabeth Lerchbaum ◽  
Winfried März ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Vitamin D ◽  
High Risk ◽  
General Population ◽  
Vitamin D Deficiency ◽  
Specific Gene ◽  
Vitamin D Status ◽  
Cvd Risk ◽  
Severe Vitamin ◽  
Increased Risk

During the last two decades, the potential impact of vitamin D on the risk of cardiovascular disease (CVD) has been rigorously studied. Data regarding the effect of vitamin D on CVD risk are puzzling: observational data indicate an inverse nonlinear association between vitamin D status and CVD events, with the highest CVD risk at severe vitamin D deficiency; however, preclinical data and randomized controlled trials (RCTs) show several beneficial effects of vitamin D on the surrogate parameters of vascular and cardiac function. By contrast, Mendelian randomization studies and large RCTs in the general population and in patients with chronic kidney disease, a high-risk group for CVD events, largely report no significant beneficial effect of vitamin D treatment on CVD events. In patients with rickets and osteomalacia, cardiovascular complications are infrequently reported, except for an increased risk of heart failure. In conclusion, there is no strong evidence for beneficial vitamin D effects on CVD risk, either in the general population or in high-risk groups. Whether some subgroups such as individuals with severe vitamin D deficiency or a combination of low vitamin D status with specific gene variants and/or certain nutrition/lifestyle factors would benefit from vitamin D (metabolite) administration, remains to be studied.

scholarly journals Association of vitamin D deficiency with incidence of type 2 diabetes in high-risk Asian subjects

2013 ◽  
Vol 97 (3) ◽  
pp. 524-530 ◽  
Author(s):  
Soo Lim ◽  
Min Joo Kim ◽  
Soo Lim ◽  
Min Joo Kim ◽  
Sung Hee Choi ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Vitamin D ◽  
High Risk ◽  
Vitamin D Deficiency

Implication of vitamin D deficiency in the development of severe forms of preeclampsia in women at high risk

2018 ◽  
Vol 9_2018 ◽  
pp. 120-125 ◽  
Author(s):  
Maltseva L.I. Maltseva ◽  
Vasilyeva E.N. Vasilyeva ◽  
Denisova T.G. Denisova ◽  
◽  
◽  
...  
Keyword(s):  
Vitamin D ◽  
High Risk ◽  
Vitamin D Deficiency

The Spectrum of Vitamin D Deficiency: Description of a Family

2017 ◽  
Vol 125 (07) ◽  
pp. 478-484 ◽  
Author(s):  
Francesco Vierucci ◽  
Marta Del Pistoia ◽  
Emioli Randazzo ◽  
Francesco Massart ◽  
Giovanni Federico
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
High Risk ◽  
Global Health ◽  
Vitamin D Deficiency ◽  
Family Members ◽  
Vitamin D Supplementation ◽  
Nutritional Rickets ◽  
Clinical Pictures ◽  
Global Health Problem

Abstract Background Vitamin D deficiency represents a global health problem, affecting children and adolescents worldwide. Objects To confirm that vitamin D deficiency can present as a spectrum of clinical pictures. Methods We diagnosed nutritional rickets in a 10-month-old infant of Senegal origin with several risk factors for vitamin D deficiency. As many of these factors affected also his cohabitant relatives, we evaluate infant’s family members (mother and 4 brothers) looking for other vitamin D deficiency-related comorbidities. Results 3 brothers had asymptomatic vitamin D deficiency and 2 of them (9.8 and 13.4 years-old) showed secondary hyperparathyroidism. The fourth brother (11.3 years-old) had nutritional rickets. Their mother was affected by osteomalacia. None of them received vitamin D supplementation. Conclusion Vitamin D deficiency may present as a spectrum of clinical pictures, representing a continuum ranging from asymptomatic/subtle conditions to overt rickets/osteomalacia. Immigrant families are at high risk for vitamin D deficiency at every age. If a case of symptomatic vitamin D deficiency is recognized, then the evaluation of the all family members is recommended, as they can have the same and/or other risk factors for vitamin D deficiency.

A novel pathway to reduce Vitamin D deficiency in a high risk population

2012 ◽  
Vol 97 (Suppl 1) ◽  
pp. A64.1-A64
Author(s):  
LC Winckworth ◽  
E Day ◽  
J Bailey ◽  
F Katz
Keyword(s):  
Vitamin D ◽  
High Risk ◽  
Vitamin D Deficiency ◽  
High Risk Population ◽  
Risk Population

Should Long-term Care Residents Be Supplemented with Vitamin D?

2008 ◽  
Vol 69 (1) ◽  
pp. 28-31 ◽  
Author(s):  
Tracy Lister
Keyword(s):  
Vitamin D ◽  
High Risk ◽  
Older People ◽  
Vitamin D Deficiency ◽  
Long Term Care ◽  
Active Form ◽  
The United States ◽  
Sufficient Evidence ◽  
Term Care

The Health Canada recommendation of 600 IU of vitamin D daily for those over age 70 may be inadequate to prevent deficiencies. A literature search was conducted to examine whether older people living in long-term care (LTC) facilities are at high risk for vitamin D deficiency and therefore should receive a minimum daily supplement of 800 IU. The search included the major databases; the search terms “elderly” and “vitamin D” were used. Articles primarily related to calcium were excluded. The results show that North American seniors generally consume a diet low in vitamin D and have limited sun exposure. The majority, particularly those living in LTC facilities, may have a vitamin D deficiency. Also contributing to deficiencies is an age-related decline in cutaneous production of vitamin D and altered metabolic processes responsible for converting vitamin D to its active form. In summary, research conducted in both Canada and the United States provides sufficient evidence to indicate that older people living in LTC facilities are at high risk for vitamin D deficiency and should receive a minimum daily supplement of 800 IU.

Successful public health action to reduce the incidence of symptomatic vitamin D deficiency

2012 ◽  
Vol 97 (11) ◽  
pp. 952-954 ◽  
Author(s):  
Robert John Moy ◽  
Eleanor McGee ◽  
Geoff D Debelle ◽  
Ian Mather ◽  
Nicholas J Shaw
Keyword(s):  
Vitamin D ◽  
High Risk ◽  
Vitamin D Deficiency ◽  
Incidence Rate ◽  
Uptake Rate ◽  
Public Awareness ◽  
Vitamin D Supplementation ◽  
Minority Population ◽  
Vitamin Supplement ◽  
Vitamin D Levels

BackgroundIn response to a resurgence of symptomatic cases of vitamin D deficiency in a high-risk predominantly ethnic minority population, a programme of universal rather than targeted vitamin D supplementation was begun with a public awareness campaign about the importance of vitamin D.ObjectiveTo evaluate the effectiveness of this programme in reducing case numbers.MethodsCases of symptomatic vitamin D deficiency in children under 5 years resident in a primary care trust catchment area presenting at local hospitals were identified through laboratory records of low vitamin D levels which were cross-checked against medical records to confirm the diagnosis. Comparisons were made of the case incidence rate, level of public knowledge and vitamin supplement uptake rate at the onset of the programme in 2005 and 4 years later.ResultsThe number of cases of symptomatic vitamin D deficiency in those under 5 years fell by 59% (case incidence rate falling from 120/100 000 to 49/100 000) despite the supplement uptake rate rising only to 17%. Public awareness of vitamin D deficiency rose to near universal levels.ConclusionsA programme of universal rather than targeted Healthy Start vitamin D supplementation for pregnant and lactating women and young children has led to a substantial decrease in cases of symptomatic vitamin D deficiency in a high-risk population. Supplementation was also started at a younger age than in the national programme. This approach has implications for the delivery of vitamin D supplementation programmes in similar populations.

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