scholarly journals Prematurity and body composition at 6, 18, and 30 years of age: Pelotas (Brazil) 2004, 1993, and 1982 birth cohorts

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Caroline Cardozo Bortolotto ◽  
Iná S. Santos ◽  
Juliana dos Santos Vaz ◽  
Alicia Matijasevich ◽  
Aluísio J. D. Barros ◽  
...  
Keyword(s):  
Body Composition ◽  
Birth Weight ◽  
Preterm Birth ◽  
Fat Mass ◽  
Population Based ◽  
Fat Free Mass ◽  
Z Score ◽  
Birth Cohorts ◽  
Air Displacement Plethysmography ◽  
Using Data

Abstract Background We aimed to investigate the association between preterm birth and body composition at 6, 18, and 30 years of age using data from three population-based birth cohort studies. Methods Gestational age (GA), defined by the date of the last menstrual period (categorized in ≤33, 34–36, and ≥ 37 weeks), was gathered in the first 24-h after delivery for all live births occurring in the city of Pelotas, Brazil, in 2004, 1993 and 1982. Body composition was assessed by air-displacement plethysmography. Outcomes included fat mass (FM, kg), percent FM (%FM), FM index (FMI, kg/m2), fat-free mass (FFM, kg); percent FFM (%FFM), FFM index (FFMI, kg/m2), body mass index (BMI, kg/m2 at 18 years in the 1993 cohort and 30 years in the 1982 cohort), and BMI Z-score (at 6 years in the 2004 cohort). We further explored the association of birth weight for GA with body composition indicators and BMI. Crude and adjusted linear regressions provided beta coefficients with 95% confidence intervals (95%CI). Results A total of 3036, 3027, and 3369 participants, respectively, from the 2004, 1993, and 1982 cohorts were analyzed. At 6 years, preterm boys (born at 34–36 weeks) presented lower adjusted mean of FM (β = − 0.80 kg, − 1.45;-0.16, p = 0.046), %FM (β = − 2.39%, − 3.90;-0.88, p = 0.008), FMI (β = − 0.70 kg/m2, − 1.13;-0.27, p = 0.004) as well as lower FFM (β = − 0.4 kg, − 0.77; − 0.12, p = 0.010) and FFMI (β = − 0.3 kg/m2, − 0.46;-0.10, p < 0.001), and BMI Z-score (β = − 0.69,; − 0.99;-0.40, p < 0.001); but higher %FFM (β = 2.4%, 0.87;-3.90, p = 0.008), when compared to boys born at term (≥37). At 30 years, FM (15.7 kg, 0.25;31.1, p = 0.102) was higher among males born at ≤33 weeks. No association was observed for females from the three cohorts and for 18-year-old males. The association of birth weight for GA with body composition and BMI was not significant in any cohort. At 6 years, SGA boys had lower FFMI than boys AGA. Conclusions Our results suggest that preterm birth is associated with decreased body fat and fat-free mass in childhood but higher fat mass in adulthood. Nevertheless, results were only significant for males. SGA boys also showed lower FFMI.

scholarly journals Prematurity and Body Fat at 6, 18, and 30 Years of Age: Pelotas (Brazil) 2004, 1993, and 1982 Birth Cohorts

2020 ◽  
Author(s):  
Caroline Cardozo Bortolotto ◽  
Iná Santos ◽  
Juliana dos Santos Vaz ◽  
Alicia Matijasevich ◽  
Aluísio J.D. B ◽  
...  
Keyword(s):  
Body Fat ◽  
Fat Mass ◽  
Population Based ◽  
Z Score ◽  
Birth Cohorts ◽  
Air Displacement Plethysmography ◽  
Live Births ◽  
Using Data ◽  
The City ◽  
Prevention Of Prematurity

Abstract Background: Our aim was to investigate the association between preterm birth and body fat at 6, 18, and 30 years of age using data from three population-based birth cohort studies. Methods: Information on gestational age (GA) gathered in the hospital of birth in the first 24-hours after the delivery was obtained for all live births occurring in the city of Pelotas, Brazil, in the years 2004, 1993 and 1982. GA was defined by the date of last menstrual period and was later categorized in ≤33, 34-36 and ≥37 weeks. Body fat was assessed by air-displacement plethysmography. Outcomes included fat mass (FM, kg), percent fat mass (%FM), fat mass index (FMI, kg/m2), and body mass index (BMI, kg/m2 at 18 years in the 1993 cohort and at 30 years in the 1982 cohort; and BMI Z-score, at 6 years in the 2004 cohort). Crude and adjusted linear regression provided beta coefficients with 95% confidence intervals (95%CI).Results: A total of 3036, 3027, and 2417 participants, respectively, from the 2004, 1993, and 1982 cohorts were analyzed. At 6 years, boys born at 34-36 weeks GA presented lower adjusted mean %FM (β: -2.91%; -4.45--1.36), FMI (β: -0.70 kg/m2 ; -1.13--0.28) and BMI Z-score (β: -0.48 kg/m2; -0.79--0.16), when compared to boys born at term (≥37). At 30 years, FM (15.6kg; 0.40-30.90), %FM (13.65%; 1.38-25.92) and FMI (5.3kg/m2; 0.30-10.37) were higher among males born at ≤33 weeks, with no statistical difference as compared to those born at term. No association was found between GA and body fat at the 1993 cohort (18 years) for both sexes. Conclusions: Given the large number of preterm infants born each year, prevention of prematurity is essential as there are possible links between body composition and diseases later in life.

scholarly journals Effect of birth weight, exclusive breastfeeding and growth in infancy on fat mass and fat free mass indices in early adolescence: an analysis of the Entebbe Mother and Baby Study (EMaBs) cohort

2019 ◽  
Vol 2 ◽  
pp. 11
Author(s):  
Jonathan Nsamba ◽  
Swaib A. Lule ◽  
Benigna Namara ◽  
Christopher Zziwa ◽  
Hellen Akurut ◽  
...  
Keyword(s):  
Body Composition ◽  
Birth Weight ◽  
Fat Mass ◽  
Exclusive Breastfeeding ◽  
Regression Coefficient ◽  
Infant Growth ◽  
Fat Free Mass ◽  
Age And Growth ◽  
Limited Data ◽  
Using Data

Background: There is limited data from Africa on the effect of pre- and post-natal growth and infant feeding on later body composition. This study's aim was to investigate the effect of birth weight, exclusive breastfeeding and infant growth on adolescent body composition, using data from a Ugandan birth cohort. Methods: Data was collected prenatally from pregnant women and prospectively from their resulting live offspring. Data on body composition (fat mass index [FMI] and fat free mass index [FFMI]) was collected from 10- and 11-year olds. Linear regression was used to assess the effect of birth weight, exclusive breastfeeding and infant growth on FMI and FFMI, adjusting for confounders. Results: 177 adolescents with a median age of 10.1 years were included in analysis, with mean FMI 2.9 kg/m2 (standard deviation (SD) 1.2), mean FFMI 12.8 kg/m2 (SD 1.4) and mean birth weight 3.2 kg (SD 0.5). 90 (50.9%) were male and 110 (63.2%) were exclusively breastfeeding at six weeks of age. Birth weight was associated with FMI in adolescence (regression coefficient β= 0.66 per kg increase in birth weight, 95% confidence interval (CI) (0.04, 1.29), P=0.02), while exclusive breastfeeding (β= -0.43, 95% CI (-1.06, 0.19), P=0.12), growth 0-6 months (β= 0.24 95% CI (-0.43, 0.92), P=0.48) and growth 6-12 months (β= 0.61, 95% CI (-0.23, 1.46), P=0.11) were not associated with FMI among adolescents. Birth weight (β= 0.91, 95% CI (0.17, 1.65), P=0.01) was associated with FFMI in adolescence. Exclusive breastfeeding (β= 0.17, 95% CI (-0.60, 0.94), P=0.62), growth 0-6 months (β= 0.56, 95% CI (-0.20, 1.33), P= 0.10), and growth 6-12 months (β= -0.02, 95% CI (-1.02, 0.99), P=0.97) were not associated with FFMI. Conclusions: Birth weight predicted body composition parameters in Ugandan early adolescents, however, exclusive breastfeeding at six weeks of age and growth in infancy did not.

scholarly journals Effect of birth weight, exclusive breastfeeding and growth in infancy on fat mass and fat free mass indices in early adolescence: an analysis of the Entebbe Mother and Baby Study (EMaBs) cohort

2020 ◽  
Vol 2 ◽  
pp. 11
Author(s):  
Jonathan Nsamba ◽  
Swaib A. Lule ◽  
Benigna Namara ◽  
Christopher Zziwa ◽  
Hellen Akurut ◽  
...  
Keyword(s):  
Body Composition ◽  
Birth Weight ◽  
Fat Mass ◽  
Exclusive Breastfeeding ◽  
Regression Coefficient ◽  
Infant Growth ◽  
Fat Free Mass ◽  
Age And Growth ◽  
Limited Data ◽  
Using Data

Background: There is limited data from Africa on the effect of pre- and post-natal growth and infant feeding on later body composition. This study's aim was to investigate the effect of birth weight, exclusive breastfeeding and infant growth on adolescent body composition, using data from a Ugandan birth cohort. Methods: Data was collected prenatally from pregnant women and prospectively from their resulting live offspring. Data on body composition (fat mass index [FMI] and fat free mass index [FFMI]) was collected from 10- and 11-year olds. Linear regression was used to assess the effect of birth weight, exclusive breastfeeding and infant growth on FMI and FFMI, adjusting for confounders. Results: 177 adolescents with a median age of 10.1 years were included in analysis, with mean FMI 2.9 kg/m2 (standard deviation (SD) 1.2), mean FFMI 12.8 kg/m2 (SD 1.4) and mean birth weight 3.2 kg (SD 0.5). 90 (50.9%) were male and 110 (63.2%) were exclusively breastfeeding at six weeks of age. Birth weight was associated with FMI in adolescence (regression coefficient β= 0.66 per kg increase in birth weight, 95% confidence interval (CI) (0.04, 1.29), P=0.02), while exclusive breastfeeding (β= -0.43, 95% CI (-1.06, 0.19), P=0.12), growth 0-6 months (β= 0.24 95% CI (-0.43, 0.92), P=0.48) and growth 6-12 months (β= 0.61, 95% CI (-0.23, 1.46), P=0.11) were not associated with FMI among adolescents. Birth weight (β= 0.91, 95% CI (0.17, 1.65), P=0.01) was associated with FFMI in adolescence. Exclusive breastfeeding (β= 0.17, 95% CI (-0.60, 0.94), P=0.62), growth 0-6 months (β= 0.56, 95% CI (-0.20, 1.33), P= 0.10), and growth 6-12 months (β= -0.02, 95% CI (-1.02, 0.99), P=0.97) were not associated with FFMI. Conclusions: Birth weight predicted body composition parameters in Ugandan early adolescents, however, exclusive breastfeeding at six weeks of age and growth in infancy did not.

scholarly journals Seasonal and Longitudinal Changes in Body Composition by Sport-Position in NCAA Division I Basketball Athletes

Sports ◽  
2018 ◽  
Vol 6 (3) ◽  
pp. 85 ◽  
Author(s):  
Jennifer Fields ◽  
Justin Merrigan ◽  
Jason White ◽  
Margaret Jones
Keyword(s):  
Body Composition ◽  
Body Mass ◽  
Body Fat ◽  
Fat Mass ◽  
Ncaa Division I ◽  
The Body ◽  
Fat Free Mass ◽  
Strength And Conditioning ◽  
Air Displacement Plethysmography ◽  
Within Subjects

The purpose of this study was to assess the body composition of male and female basketball athletes (n = 323) across season, year, and sport-position using air displacement plethysmography. An independent sample t-test assessed sport-position differences. An analysis of variance was used to assess within-subjects across season (pre-season, in-season, and off-season), and academic year (freshman, sophomore, and junior). For both men and women basketball (MBB, WBB) athletes, guards had the lowest body fat, fat mass, fat free mass, and body mass. No seasonal differences were observed in MBB, but following in-season play for WBB, a reduction of (p = 0.03) in fat free mass (FFM) was observed. Across years, MBB showed an increase in FFM from freshman to sophomore year, yet remained unchanged through junior year. For WBB across years, no differences occurred for body mass (BM), body fat (BF%), and fat mass (FM), yet FFM increased from sophomore to junior year (p = 0.009). Sport-position differences exist in MBB and WBB: Guards were found to be smaller and leaner than forwards. Due to the importance of body composition (BC) on athletic performance, along with seasonal and longitudinal shifts in BC, strength and conditioning practitioners should periodically assess athletes BC to ensure preservation of FFM. Training and nutrition programming can then be adjusted in response to changes in BC.

scholarly journals New charts for the assessment of body composition, according to air-displacement plethysmography, at birth and across the first 6 mo of life

2019 ◽  
Vol 109 (5) ◽  
pp. 1353-1360 ◽  
Author(s):  
Tom Norris ◽  
Sara E Ramel ◽  
Patrick Catalano ◽  
Carol ni Caoimh ◽  
Paola Roggero ◽  
...  
Keyword(s):  
United States ◽  
Body Composition ◽  
Preterm Infants ◽  
Fat Mass ◽  
Gestational Age ◽  
The United States ◽  
Fat Free Mass ◽  
Term Infants ◽  
Air Displacement Plethysmography ◽  
Young Infants

ABSTRACT Background Air-displacement plethysmography (ADP) is a good candidate for monitoring body composition in newborns and young infants, but reference centile curves are lacking that allow for assessment at birth and across the first 6 mo of life. Objective Using pooled data from 4 studies, we aimed to produce new charts for assessment according to gestational age at birth (30 + 1 to 41 + 6 wk) and postnatal age at measurement (1–27 wk). Methods The sample comprised 222 preterm infants born in the United States who were measured at birth; 1029 term infants born in Ireland who were measured at birth; and 149 term infants born in the United States and 57 term infants born in Italy who were measured at birth, 1 and 2 wk, and 1, 2, 3, 4, 5, and 6 mo of age. Infants whose birth weights were <3rd or >97th centile of the INTERGROWTH-21st standard were excluded, thereby ensuring that the charts depict body composition of infants whose birth weights did not indicate suboptimal fetal growth. Sex-specific centiles for fat mass (kg), fat-free mass (kg), and percentage body fat were estimated using the lambda-mu-sigma (LMS) method. Results For each sex and measure (e.g., fat mass), the new charts comprised 2 panels. The first showed centiles according to gestational age, allowing term infants to be assessed at birth and preterm infants to be monitored until they reached term. The second showed centiles according to postnatal age, allowing all infants to be monitored to age 27 wk. The LMS values underlying the charts were presented, enabling researchers and clinicians to convert measurements to centiles and z scores. Conclusions The new charts provide a single tool for the assessment of body composition, according to ADP, in infants across the first 6 mo of life and will help enhance early-life nutritional management.

One- and two-year change in body composition as measured by DXA in a population-based cohort of older men and women

2003 ◽  
Vol 94 (6) ◽  
pp. 2368-2374 ◽  
Author(s):  
Marjolein Visser ◽  
Marco Pahor ◽  
Frances Tylavsky ◽  
Stephen B. Kritchevsky ◽  
Jane A. Cauley ◽  
...  
Keyword(s):  
Body Composition ◽  
Body Mass ◽  
Fat Mass ◽  
Population Based ◽  
Fat Free Mass ◽  
Simultaneous Increase ◽  
Total Body Mass ◽  
Men And Women ◽  
Total Body

Changing body composition has been suggested as a pathway to explain age-related functional decline. No data are available on the expected changes in body composition as measured by dual-energy X-ray absorptiometry (DXA) in a population-based cohort of older persons. Body composition data at baseline, 1-yr follow-up, and 2-yr follow-up was measured by DXA in 2,040 well-functioning black and white men and women aged 70–79 yr, participants of the Health, Aging, and Body Composition Study. After 2 yr, a small decline in total body mass was observed (men: −0.3%, women: −0.4%). Among men, fat-free mass and appendicular lean soft tissue mass (ALST) decreased by −1.1 and −0.8%, respectively, which was masked by a simultaneous increase in total fat mass (+2.0%). Among women, a decline in fat-free mass was observed after 2 yr only (−0.6%) with no change in ALST and body fat mass. After 2 yr, the decline in ALST was greater in blacks than whites. Change in total body mass was associated with change in ALST ( r = +0.58 to +0.70; P < 0.0001). Among participants who lost total body mass, men lost relatively more ALST than women, and blacks lost relatively more ALST than whites. In conclusion, the mean change in body composition after a 1- to 2-yr follow-up was 1–2% with a high interindividual variability. Loss of ALST was greater in men compared with women, and greater in blacks compared with whites, suggesting that men and blacks may be more prone to muscle loss.

scholarly journals Body composition among long distance runners

2020 ◽  
Vol 66 (2) ◽  
pp. 180-186
Author(s):  
Joana Rosado ◽  
João P. Duarte ◽  
Paulo Sousa-e-Silva ◽  
Daniela C. Costa ◽  
Diogo V. Martinho ◽  
...  
Keyword(s):  
Body Composition ◽  
Fat Mass ◽  
Adult Male ◽  
Bioelectrical Impedance ◽  
The Body ◽  
Fat Free Mass ◽  
Body Density ◽  
Distance Runners ◽  
Long Distance ◽  
Air Displacement Plethysmography

SUMMARY OBJECTIVE The current study aimed to examine the body composition of adult male ultra-trail runners (UTR) according to their level of participation (regional UTR-R, vs. national UTR-N). METHODS The sample was composed of 44 adult male UTR (aged 36.5±7.2 years; UTR-R: n=25; UTR-N: n=19). Body composition was assessed by air displacement plethysmography, bioelectrical impedance, and dual-energy X-ray absorptiometry. In addition, the Food Frequency Questionnaire (FFQ) was applied. A comparison between the groups was performed using independent samples t-test. RESULTS Significant differences between groups contrasting in the competitive level were found for chronological age (in years; UTR-R: 38.8±8.2 vs. UTR-N: 33.5±4.1); body density (in L.kg-1; UTR-R: 1.062±0.015 vs. UTR-N: 1.074±0.009); and fat mass (in kg; UTR-R: 12.7±6.8 vs. UTR-N: 7.6±2.7). CONCLUSION UTR-N were younger, presented higher values for body density, and had less fat mass, although no significant differences were found for fat-free mass. The current study evidenced the profile of long-distance runners and the need for weight management programs to regulate body composition.

scholarly journals Bone mineral density and body composition in adolescents with failure to thrive

2010 ◽  
Vol 8 (2) ◽  
pp. 168-174
Author(s):  
Thiago Sacchetto de Andrade ◽  
Luiz Anderson Lopes ◽  
Marcelo de Medeiros Pinheiro ◽  
Vera Lucia Szejnfeld ◽  
José Augusto de Aguiar Carrazedo Taddei
Keyword(s):  
Bone Mineral Density ◽  
Body Composition ◽  
Bone Mass ◽  
Bone Mineral ◽  
Fat Mass ◽  
Failure To Thrive ◽  
Fat Free Mass ◽  
Z Score ◽  
Mineral Density ◽  
Total Fat

ABSTRACT Objective To evaluate bone mineral mass in adolescents with failure to thrive in relation to body composition. Methods A case control study involving 126 adolescents (15 to 19 years), in final puberty maturation being 76 eutrophic and 50 with failure to thrive (genetic or constitutional delay of growth), of matching ages, gender and pubertal maturation. The weight, height and calculated Z score for height/age and body mass index; bone mineral content, bone mineral density and adjusted bone mineral density were established for total body, lower back and femur; total fat-free mass and height-adjusted fat-free mass index, total fat mass and height-adjusted. The statistical analyses were performed using the Student's t-test (weight, height and body composition); Mann-Whitney test (bone mass) and multiple linear regression (bone mass determinants). Results weight, height and height/age Z-score were significantly higher among eutrophic subjects. Both groups did not show statistically significant differences for fat mass, percentage of fat mass, total fat mass height adjusted and fat-free mass index height sadjusted. However, total free fat maass was smaller for the failure to thrive group. Conclusions There was no statistically significant difference for bone mass measurements among adolescents with failure to thrive; however, the factors that determine bone mass formation should be better studied due to the positive correlation with free fat mass detected in these individuals.

scholarly journals DNA methylation in infants with low and high body fatness

BMC Genomics ◽  
2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Pontus Henriksson ◽  
Antonio Lentini ◽  
Signe Altmäe ◽  
David Brodin ◽  
Patrick Müller ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Body Composition ◽  
Birth Weight ◽  
Health Outcomes ◽  
Fat Mass ◽  
Later Life ◽  
Fat Free Mass ◽  
Buccal Cells ◽  
Body Fatness ◽  
High Body

Abstract Background Birth weight is determined by the interplay between infant genetics and the intrauterine environment and is associated with several health outcomes in later life. Many studies have reported an association between birth weight and DNA methylation in infants and suggest that altered epigenetics may underlie birthweight-associated health outcomes. However, birth weight is a relatively nonspecific measure of fetal growth and consists of fat mass and fat-free mass which may have different effects on health outcomes which motivates studies of infant body composition and DNA methylation. Here, we combined genome-wide DNA methylation profiling of buccal cells from 47 full-term one-week old infants with accurate measurements of infant fat mass and fat-free mass using air-displacement plethysmography. Results No significant association was found between DNA methylation in infant buccal cells and infant body composition. Moreover, no association between infant DNA methylation and parental body composition or indicators of maternal glucose metabolism were found. Conclusions Despite accurate measures of body composition, we did not identify any associations between infant body fatness and DNA methylation. These results are consistent with recent studies that generally have identified only weak associations between DNA methylation and birthweight. Although our results should be confirmed by additional larger studies, our findings may suggest that differences in DNA methylation between individuals with low and high body fatness may be established later in childhood.

scholarly journals Cord blood leptin and gains in body weight and fat mass during infancy

2016 ◽  
Vol 175 (5) ◽  
pp. 403-410 ◽  
Author(s):  
Carol ní Chaoimh ◽  
Deirdre M Murray ◽  
Louise C Kenny ◽  
Alan D Irvine ◽  
Jonathan O’B Hourihane ◽  
...  
Keyword(s):  
Body Composition ◽  
Weight Gain ◽  
Cord Blood ◽  
Fat Mass ◽  
Early Life ◽  
Fat Free Mass ◽  
Birth Cohort Study ◽  
Fat Mass Index ◽  
Air Displacement Plethysmography ◽  
Design And Methods

Objectives Low early-life leptin concentrations may promote faster weight gain in infancy. We aimed to examine the associations between cord blood leptin concentrations and changes in weight and body composition during infancy. Design and methods Serum leptin was measured at 15 weeks gestation, in umbilical cord blood collected at delivery and at 2 years in 334 children from the Cork Baseline Birth Cohort Study. Body composition was measured at 2 days and 2 months using air displacement plethysmography. Conditional change in weight standard deviation scores over a number of age intervals in the first 2 years and conditional change in fat mass index (FMI) and fat-free mass index (FFMI) (kg/(length)m2) between birth and 2 months were calculated and associations with cord blood leptin were examined using linear regression. Results At birth, cord blood leptin was positively correlated with FMI (r = 0.48, P < 0.001) and showed a weaker correlation with FFMI (r = 0.12, P = 0.05). After adjustment for confounders, higher cord blood leptin (per ng/mL) was associated with slower conditional weight gain between birth and 2 months (β (95% CI): −0.024 (−0.035, −0.013), P < 0.001) but not over subsequent age intervals. Cord blood leptin was also inversely associated with conditional change in FMI (−0.021 (−0.034, −0.007, P = 0.003) but not FFMI between birth and 2 months. Conclusions These are the first data to show that associations between higher cord blood leptin and slower weight gain during infancy are driven by lower increases in adiposity, at least in early infancy.

Sign in / Sign up

Export Citation Format

Share Document