scholarly journals Association between body mass index and fragility fracture in postmenopausal women: a cross-sectional study using Korean National Health and Nutrition Examination Survey 2008–2009 (KNHANES IV)

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jihan Kim ◽  
Sami Lee ◽  
Sung Soo Kim ◽  
Jong-Pyo Lee ◽  
Jong Sung Kim ◽  
...  

Abstract Background The present study examined the relationship between body mass index (BMI) and the risk for fragility fractures in postmenopausal Korean women. Methods Among subjects who participated in the 4th Korea National Health and Nutrition Examination Survey (2008–2009), 2114 women ≥ 40 years of age were included. BMI was based on standards set by the Korean Society for the Study of Obesity, as follows: < 18.5 kg/m2, underweight; 18.5 ≤ to < 25 kg/m2, normal weight; and ≥ 25 kg/m2, obese. Subjects were also divided into three groups according to the location of fragility fracture: spine, hip, or wrist. Results The mean (± SD) rate of fragility fracture was significantly different among the three groups: 5.9 ± 2.9% (underweight), 1.1 ± 0.3% (normal weight), and 3.0 ± 0.7% (obese) (p = 0.001). After correcting for age, family history, and treatment history of osteoporosis and rheumatoid arthritis, smoking and drinking status, and level of exercise, multivariable regression analysis revealed that the odds ratio for fragility fracture in the underweight group was 5.48 [95% confidence interval (CI) 1.80–16.73] and 3.33 (95% CI 1.61–6.87) in the obese group. After subdividing fragility fractures into vertebral and non-vertebral, the odds ratio for vertebral fracture in the underweight group was 5.49 (95% CI 1.31–23.09) times higher than that in the normal weight group; in the obese group, the non-vertebral fracture odds ratio was 3.87 (95% CI 1.45–10.33) times higher. Analysis of non-vertebral fractures in the obese group revealed an odds ratio for fracture 22.05 (95% CI 1.33–365.31) times higher for hip fracture and 3.85 (95% CI 1.35–10.93) times higher for wrist fracture. Conclusions Obesity and underweight increased the risk for fragility fractures in postmenopausal Korean women.

2020 ◽  
Author(s):  
Jihan Kim ◽  
Sami Lee ◽  
Sung Soo Kim ◽  
Jong-Pyo Lee ◽  
Jong Sung Kim ◽  
...  

Abstract Background: The present study examined the relationship between body mass index (BMI) and the risk for fragility fractures in postmenopausal Korean women. Method: Among subjects who participated in the 4th National Health and Nutrition Examination Survey (2008-2009), 2114 women ≥ 40 years of age were included. BMI was based on standards set by the Korean Society for the Study of Obesity, as follows: <18.5 kg/m2, underweight; 18.5 ≤ to <25 kg/m2, normal weight; and ≥25 kg/m2, obese. Subjects were also divided into three groups according to the location of fragility fracture: spine, hip, or wrist. Results: The mean (± SD) rate of fragility fracture was significantly different among the three groups: 5.9±2.9% (underweight), 1.1±0.3% (normal weight), and 3.0±0.7% (obese) (p=0.001). After correcting for age, family history, and treatment history of osteoporosis and rheumatoid arthritis, smoking and drinking status, and level of exercise, multivariable regression analysis revealed that the odds ratio for fragility fracture in the underweight group was 5.51 (95% confidence interval [CI] 1.88–16.13) and 3.19 (95% CI 1.51–6.74) in the obese group. After subdividing fragility fractures into vertebral and non-vertebral, the odds ratio for vertebral fracture in the underweight group was 6.05 (95% CI 1.61–22.68) times higher than that in the normal weight group; in the obese group, the non-vertebral fracture odds ratio was 3.73 (95% CI 1.33–10.44) times higher. Analysis of non-vertebral fractures in the obese group revealed an odds ratio for fracture 8.29 (95% CI 1.04–66.37) times higher for hip fracture and 3.73 (95% CI 1.21–11.43) times higher for wrist fracture. Conclusions: Obesity and underweight increased the risk for fragility fractures in postmenopausal Korean women. As such, it is important for this patient population to maintain bone health through proper weight management, sufficient exercise, and regular examination of bone density.


2021 ◽  
Author(s):  
Jihan Kim ◽  
Sami Lee ◽  
Sung Soo Kim ◽  
Jong-Pyo Lee ◽  
Jong Sung Kim ◽  
...  

Abstract Background The present study examined the relationship between body mass index (BMI) and the risk for fragility fractures in postmenopausal Korean women. Method Among subjects who participated in the 4th National Health and Nutrition Examination Survey (2008-2009), 2114 women ≥ 40 years of age were included. BMI was based on standards set by the Korean Society for the Study of Obesity, as follows: <18.5 kg/m 2 , underweight; 18.5 ≤ to <25 kg/m 2 , normal weight; and ≥25 kg/m 2 , obese. Subjects were also divided into three groups according to the location of fragility fracture: spine, hip, or wrist. Results The mean (± SD) rate of fragility fracture was significantly different among the three groups: 5.9±2.9% (underweight), 1.1±0.3% (normal weight), and 3.0±0.7% (obese) (p=0.001). After correcting for age, family history, and treatment history of osteoporosis and rheumatoid arthritis, smoking and drinking status, and level of exercise, multivariable regression analysis revealed that the odds ratio for fragility fracture in the underweight group was 5.48 (95% confidence interval [CI] 1.80–16.73) and 3.33 (95% CI 1.61–6.87) in the obese group. After subdividing fragility fractures into vertebral and non-vertebral, the odds ratio for vertebral fracture in the underweight group was 5.49 (95% CI 1.31–23.09) times higher than that in the normal weight group; in the obese group, the non-vertebral fracture odds ratio was 3.87 (95% CI 1.45–10.33) times higher. Analysis of non-vertebral fractures in the obese group revealed an odds ratio for fracture 22.05(95% CI 1.33–365.31) times higher for hip fracture and 3.85 (95% CI 1.35–10.93) times higher for wrist fracture. Conclusions Obesity and underweight increased the risk for fragility fractures in postmenopausal Korean women.


Author(s):  
Hwi Jun Kim ◽  
So Yeon Oh ◽  
Dong-Woo Choi ◽  
Eun-Cheol Park

Previous research suggests that adult men consume larger amounts of calories while eating-out than when eating meals prepared at home. Therefore, this study aimed to investigate the association between the daily eating-out rate and body mass index (BMI) in the Korean population. The study used data from 18,019 individuals aged ≥19 years who participated in the Korea National Health and Nutrition Examination Survey (KNHANES) from 2013 to 2016. BMI was measured according to the Asia-Pacific BMI measurement criteria. A multinomial logistic regression analysis was used to examine the validity of the association between the eating-out rate and BMI. In this population, women with higher eating-out rates were found to have higher BMIs. Specifically, the risks of becoming obese or overweight increased among those with a 1%–50% (obesity odds ratio (OR) = 1.28, 95% confidence interval [CI]: 1.09–1.51; overweight OR = 1.38, 95% CI: 1.14–1.64) or 51%–100% daily eating-out rate (obesity OR = 1.51, 95% CI: 1.24–1.84; overweight OR = 1.50, 95% CI: 1.20–1.87), relative to those who reported never eating-out. By contrast, no statistically significant association between the daily eating-out rate and BMI was observed among men. Notably, we observed positive associations of the daily eating-out rate with obesity and being overweight in South Korean women, but not men. Our findings suggest that education about proper habits when eating-out is needed to prevent obesity.


2016 ◽  
Vol 113 (3) ◽  
pp. 572-577 ◽  
Author(s):  
Andrew Stokes ◽  
Samuel H. Preston

Analyses of the relation between obesity and mortality typically evaluate risk with respect to weight recorded at a single point in time. As a consequence, there is generally no distinction made between nonobese individuals who were never obese and nonobese individuals who were formerly obese and lost weight. We introduce additional data on an individual’s maximum attained weight and investigate four models that represent different combinations of weight at survey and maximum weight. We use data from the 1988–2010 National Health and Nutrition Examination Survey, linked to death records through 2011, to estimate parameters of these models. We find that the most successful models use data on maximum weight, and the worst-performing model uses only data on weight at survey. We show that the disparity in predictive power between these models is related to exceptionally high mortality among those who have lost weight, with the normal-weight category being particularly susceptible to distortions arising from weight loss. These distortions make overweight and obesity appear less harmful by obscuring the benefits of remaining never obese. Because most previous studies are based on body mass index at survey, it is likely that the effects of excess weight on US mortality have been consistently underestimated.


2007 ◽  
Vol 53 (12) ◽  
pp. 2152-2159 ◽  
Author(s):  
Yuan-Xiang Meng ◽  
Earl S Ford ◽  
Chaoyang Li ◽  
Alexander Quarshie ◽  
Ahmad M Al-Mahmoud ◽  
...  

Abstract Background: Increased C-reactive protein (CRP) concentration and insulin resistance (IR) are associated with increased rates of adverse cardiovascular events. We sought to examine the relationship of CRP with surrogate measures of IR among nondiabetic adults in the US. Methods: We conducted analyses using data from the National Health and Nutrition Examination Survey 1999–2002. We analyzed a nationally representative sample of 2514 men and nonpregnant women age ≥20 years who were non-Hispanic white, non-Hispanic black, or Mexican American. Results: After adjustment for age, sex, race/ethnicity, smoking status, systolic blood pressure, and serum concentrations of HDL cholesterol, LDL cholesterol, and triglyceride, CRP was significantly associated with 10 IR measures (all P values &lt;0.01). The strength of the association attenuated after further adjustment for waist circumference (change in adjusted regression coefficients ranging from 60.0% to 75.1%). The association of CRP with each IR surrogate was similar (standardized regression coefficient ranges from 0.06 to 0.09). The association of CRP (&gt;3 vs &lt;1 mg/L) with the homeostasis model for assessment of IR (≥75th vs &lt;75th percentile) was statistically significant among people with a body mass index ≥30 kg/m2 (odds ratio, 2.6; 95% CI, 1.3–5.1) or with a body mass index &lt;25 kg/m2 (odds ratio, 2.5; 95% CI, 1.5–4.2). Conclusions: CRP was significantly associated with the surrogate measures of IR among nondiabetic adults. Obesity may play an important role in the association of CRP with IR in this nationally representative sample.


Cephalalgia ◽  
2008 ◽  
Vol 28 (12) ◽  
pp. 1270-1276 ◽  
Author(s):  
ES Ford ◽  
C Li ◽  
WS Pearson ◽  
G Zhao ◽  
TW Strine ◽  
...  

The objective was to study the cross-sectional association between body mass index (BMI) and the prevalence of severe headaches or migraines in a national sample of US adults. We used data from 7601 men and women aged ≥ 20 years who participated in the National Health and Nutrition Examination Survey 1999-2002. The age-adjusted prevalence of severe headaches or migraines during the previous 3 months was 34.0, 18.9, 20.7 and 25.9± among participants with a BMI< 18.5, 18.5 to< 25, 25 to< 30 and ≥ 30 kg/m2, respectively. After adjusting for a variety of covariates in a logistic regression model, those with a BMI< 18.5 kg/m2 [odds ratio (OR) 2.01; 95± confidence interval (CI) 1.34, 3.02] or ≥ 30 kg/m2 (OR 1.37; 95± CI 1.09, 1.72) had a significantly elevated OR for having a headache compared with participants with a BMI of 18.5-< 25 kg/m2. BMI is associated with the prevalence of severe headaches or migraines in a non-linear manner.


Author(s):  
Ha-Jin Jang ◽  
Hannah Oh

Few studies have comprehensively examined the nationwide trends in overall and abdominal obesity prevalence and related sociodemographic inequalities in Korea. In the Korea National Health and Nutrition Examination Survey 1998–2018, we estimated the age-standardized prevalence of overall (body mass index ≥ 25 kg/m2) and abdominal obesity (waist circumference ≥ 90 cm men, ≥85 cm women) in each sociodemographic subgroup of Korean adults (aged 19–79 years). For each survey year, weighted logistic regression was performed to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for the associations between obesity prevalence and sociodemographic factors. During the study period, the prevalence of overall and abdominal obesity increased in men (24.8% to 42.4%; 20.1% to 32.1%; respectively) but only a small change was observed in women (26.5% to 26.0%; 22.7% to 20.9%; respectively). Obesity prevalence increased in all sociodemographic groups of men but varied across groups in women. In women, income (4th vs. 1st quartiles in 2016–2018: OR (95% CI) = 0.66 (0.56–0.78) overall obesity; 0.60 (0.51–0.71) abdominal obesity) and education (college or higher vs. high school or less: 0.62 (0.54–0.72) overall obesity; 0.58 (0.50–0.68) abdominal obesity) were inversely associated with obesity prevalence, and the gaps became more pronounced since 2007. Our data suggest that the inequalities in obesity prevalence by sex and by socioeconomic status have become more apparent over time in Korea.


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