scholarly journals Analysis of the etiologies of female infertility in Yunnan minority areas

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Fen Zhang ◽  
Qing Feng ◽  
Linna Yang ◽  
Xuelian Liu ◽  
Lingyun Su ◽  
...  

Abstract Background The present study aims to provide a comparative analysis of the etiologies of female infertility between Dehong, on the Yunnan Frontier, and Kunming. Methods A retrospective study, which included 941 infertile females in Kunming who were treated in the First People’s Hospital of Yunnan Province and infertile females who were treated in the local hospital in Dehong from January 2016 to November 2018, was conducted. A comparative analysis of the etiologies of infertility in the two regions was then carried out. Results In patients with primary infertility, ovulation disorder (15.03%) was the main cause of infertility in Kunming, and pelvic inflammatory disease (25.59%) was the main cause in Dehong. With regard to secondary infertility, although pelvic inflammatory disease was the main cause of infertility in both regions, the incidence of intrauterine adhesions in Kunming was significantly higher than in Dehong. Conclusions The etiology of infertility showed different epidemiological characteristics depending on the region, hence individualized treatment should be given accordingly

2019 ◽  
Vol 69 (9) ◽  
pp. 1517-1525 ◽  
Author(s):  
Casper D J den Heijer ◽  
Christian J P A Hoebe ◽  
Johanna H M Driessen ◽  
Petra Wolffs ◽  
Ingrid V F van den Broek ◽  
...  

Abstract Background We evaluated the risk of pelvic inflammatory disease (PID), ectopic pregnancy, and infertility in women with a previous Chlamydia trachomatis (CT) diagnosis compared with women who tested negative for CT and CT untested women, considering both targeted and incidental (ie, prescribed for another indication) use of CT-effective antibiotics. Methods This was a retrospective study of women aged 12–25 years at start of follow-up within the Clinical Practice Research Datalink GOLD database linked to index of multiple deprivation quintiles, 2000–2013. CT test status and antibiotic use were determined in a time-dependent manner. Risk of PID, ectopic pregnancy, or female infertility were evaluated using of Cox proportional hazard models. Results We studied 857 324 women, contributing 6 457 060 person-years. Compared with women who tested CT-negative, women who tested CT-positive had an increased risk of PID (adjusted hazard ratio [aHR], 2.36; 95% confidence interval [CI], 2.01–2.79), ectopic pregnancy (aHR, 1.87; 95% CI, 1.38–2.54), and infertility (aHR, 1.85; 95% CI, 1.27–2.68). The PID risk was higher for women with 2 or more positive CT tests than those with 1 positive test. PID risk increased with the number of previous antibiotic prescriptions, regardless of CT test status. Conclusions We showed an association between CT-positive tests and 3 adverse reproductive health outcomes. Moreover, this risk increased with repeat CT infections. CT-effective antibiotic use showed no decreased risks of subsequent PID regardless of CT history. Our results confirm the reproductive health burden of CT, which requires adequate public health interventions.


1997 ◽  
Vol 119 (1) ◽  
pp. 49-52 ◽  
Author(s):  
I. SIMMS ◽  
P. A. ROGERS ◽  
A. NICOLL

A retrospective study was carried out to determine the recent epidemiology of ectopic pregnancy in England between the biennial years 1988/9 and 1992/3. The number of ectopic pregnancy cases were combined with numbers of conceptions and the rates analysed for trend over time. The incidence of ectopic pregnancy rose significantly (P=0·05) over this period. However, this could be entirely explained by increasing numbers of births in older women and a highly significant positive association was found between risk of ectopic pregnancy and maternal age (P<0·0001). Over the study period the incidence of ectopic pregnancy in women aged 40 years or more was over 14 times that observed in those under 16 years of age. It is suggested that this reflects cumulative risk of acquiring pelvic inflammatory disease. The surveillance of ectopic pregnancy provides a useful indicator of the level of reproductive morbidity in women.


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