scholarly journals Pigmentary keratitis in pugs in the United Kingdom: prevalence and associated features

2019 ◽  
Vol 15 (1) ◽  
Author(s):  
S. Maini ◽  
R. Everson ◽  
C. Dawson ◽  
Y. M. Chang ◽  
C. Hartley ◽  
...  

Abstract Background Pigmentary keratitis (PK) is commonly recognised in Pugs, but its aetiology is not completely understood. The aim of this study was to determine the prevalence and associated features of PK in Pugs in the United Kingdom (UK). Results A total of 210 Pugs (420 eyes) were recruited from 12 UK dog shows and social events. The median age of Pugs recruited was 2.50 years (range 0.25–16.25 years). Pigmentary keratitis was detected in 369/420 (87.8%) eyes and in at least one eye 193/210 (91.9%) Pugs, of which 17/193 (8.8%) were affected unilaterally and 176/193 (91.2%) bilaterally. Pigmentary keratitis was typically mild to moderate (46.3 and 49.9% of eyes, respectively). Detection of PK was significantly associated with increased age (P = 0.002) and the presence of medial entropion of the lower eyelid (MELE) (P = 0.001). Severity of PK was significantly associated with the grade of MELE (P < 0.001). There was also a correlation between the presence of limbal pigment and PK (P = 0.036) that warrants further study. Conclusions This study estimated a high disease prevalence of PK in UK Pugs, and demonstrated significant associations with age and the presence of MELE. These associations, which have not been previously reported, offer an insight into the underlying pathophysiology of this condition in Pugs. The results encourage further population research, such as prospective longitudinal studies. These findings also support the development of clinical and breeding strategies based on the reduction of MELE and, possibly, limbal pigment.

2021 ◽  
Vol 36 (1) ◽  
pp. 155-164
Author(s):  
Richard Barnes

Abstract On 30 September 2020, the United Kingdom and Norway signed the Framework Agreement on Fisheries that will provide the basis for future cooperation in the sustainable management of their fisheries. The Agreement is the first such agreement adopted by the UK following its decision to the leave the European Union. This note provides some background to the Agreement and examines its key features. Whilst the content of the Agreement appears to be rather basic, this is broadly consistent with other framework agreements, and it does provide some insight into the direction and focus of fisheries management in the North Sea, and how cooperation may develop between coastal States and the European Union.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Babu Karavadra ◽  
Andrea Stockl ◽  
Edward Prosser-Snelling ◽  
Paul Simpson ◽  
Edward Morris

Abstract Background The aim of this national survey was to explore pregnant women’s perceptions of COVID-19 and their healthcare experiences. Methods Through patient and public involvement, a questionnaire was developed and advertised via the BBC website, Twitter and other online media during May 2020. The findings were analysed by qualitative thematic analysis. Women who are currently pregnant, or who have delivered during the COVID-19 pandemic were invited to partake in a national online survey. Results One thousand four hundred fifty-one participants replied to the online questionnaire. Participants provided significant insight into the perceived barriers to seeking healthcare during this pandemic. These include ‘not wanting to bother anyone’, ‘lack of wider support from allied healthcare workers’ and the influence of the media. Other concerns included the use of virtual clinics antenatally and their acceptability to patients, the presence of birthing partners, and the way in which information is communicated about rapidly changing and evolving services. The influence of the media has also had a significant impact on the way women perceive hospital care in light of COVID-19 and for some, this has shaped whether they would seek help. Conclusions This is the first ever reported study in the United Kingdom to explore pregnant women’s perceptions of COVID-19 and their subsequent healthcare experiences. It has also provided insight into perceived barriers into seeking care as well as maternal concerns antenatally, intrapartum and postpartum.


2020 ◽  
Author(s):  
Anokha Oomman Joseph ◽  
Janso Padickakudi Joseph ◽  
Haritharan Nageswaran ◽  
Viswa Retnasingam Rajalingam ◽  
Amit Sharma ◽  
...  

2015 ◽  
Vol 23 (1) ◽  
pp. 48-59 ◽  
Author(s):  
Alison M Devlin ◽  
Marilyn McGee-Lennon ◽  
Catherine A O’Donnell ◽  
Matt-Mouley Bouamrane ◽  
Ruth Agbakoba ◽  
...  

Abstract Objective To identify implementation lessons from the United Kingdom Delivering Assisted Living Lifestyles at Scale (dallas) program—a large-scale, national technology program that aims to deliver a broad range of digital services and products to the public to promote health and well-being. Materials and Methods Prospective, longitudinal qualitative research study investigating implementation processes. Qualitative data collected includes semi-structured e-Health Implementation Toolkit–led interviews at baseline/mid-point ( n = 38), quarterly evaluation, quarterly technical and barrier and solutions reports, observational logs, quarterly evaluation alignment interviews with project leads, observational data collected during meetings, and ethnographic data from dallas events ( n &gt; 200 distinct pieces of qualitative data). Data analysis was guided by Normalization Process Theory, a sociological theory that aids conceptualization of implementation issues in complex healthcare settings. Results Five key challenges were identified: 1) The challenge of establishing and maintaining large heterogeneous, multi-agency partnerships to deliver new models of healthcare; 2) The need for resilience in the face of barriers and set-backs including the backdrop of continually changing external environments; 3) The inherent tension between embracing innovative co-design and achieving delivery at pace and at scale ; 4) The effects of branding and marketing issues in consumer healthcare settings; and 5) The challenge of interoperability and information governance, when commercial proprietary models are dominant. Conclusions The magnitude and ambition of the dallas program provides a unique opportunity to investigate the macro level implementation challenges faced when designing and delivering digital health and wellness services at scale. Flexibility, adaptability, and resilience are key implementation facilitators when shifting to new digitally enabled models of care.


2007 ◽  
Vol 9 (1) ◽  
pp. 57-65
Author(s):  
Sam Middlemiss

While numerous articles have now been written on the age regulations 1 they tend to concentrate on the broad detail of the Regulations and their likely impact in the United Kingdom, whereas this article, while also involving analysis of the legal rules, concentrates on one aspect of the Regulations namely, age harassment. It will also involve consideration of the equivalent law in the United States because they have a much more mature set of legal rules dealing with this type of activity. The difficulty of making such a comparison is that the legal rules in the two jurisdictions are very different and the UK version is much more favourable than its US counterpart. Nevertheless, it is this writer’s view that identifying the various problems that have arisen in the US with implementing their age legislation in respect of age harassment over almost forty years 2 will prove instructive and valuable to those persons required to comply with the new law in the UK and offer valuable insight into the legal treatment of this issue.


2011 ◽  
Vol 44 (1) ◽  
pp. 101-106 ◽  
Author(s):  
J. L. IRELAND ◽  
P. D. CLEGG ◽  
C. M. McGOWAN ◽  
S. A. McKANE ◽  
K. J. CHANDLER ◽  
...  

1977 ◽  
Author(s):  
A. Aronstam ◽  
M.J. Inwood ◽  
P.G. Arblaster

A survey of Canadian and British physicians actively treating hemophiliacs was undertaken to assess whether the difference in the two countries’ health care delivery systems influenced their attitudes to prophylactic therapy. Questionnaires defining prophylactic therapy and relating its use to a number of activities were sent to directors of hemophilia treatment centres representing adequate geographic coverage in both countries. 47 replies were received (10/13 Canadian and 37/40 British). 50% of the United Kingdom (UK) physicians used prophylactic therapy on occasion as compared to 92% of Canadian physicians. However, only 20% UK physicians versus 80% Canadian used it on a routine basis for selected patients. 43% British physicians compared to 50% Canadian gave prophylaxis prior to certain athletic or social events. The mean dose of Factor VIII or IX given by Canadian physicians was higher and individual doses were given more frequently. The increased acceptability of this form of therapy in Canada may be related to easier availability of Factor concentrates and a more flexible health care system.


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