scholarly journals Serum levels of environmental pollutants is a risk factor for breast cancer in Inuit: a case control study

2017 ◽  
Vol 16 (1) ◽  
Author(s):  
Maria Wielsøe ◽  
Peder Kern ◽  
Eva Cecilie Bonefeld-Jørgensen
Keyword(s):  
Breast Cancer ◽  
Risk Factor ◽  
Case Control Study ◽  
Environmental Pollutants ◽  
Serum Levels ◽  
Case Control ◽  
Control Study

scholarly journals Organochlorine pesticide exposure as a risk factor for breast cancer in young Indian women: A case–control study

2019 ◽  
Vol 08 (04) ◽  
pp. 212-214 ◽  
Author(s):  
Navneet Kaur ◽  
Srikant K Swain ◽  
Basudev D Banerjee ◽  
Tusha Sharma ◽  
Thammineni Krishnalata
Keyword(s):  
Breast Cancer ◽  
Risk Factor ◽  
Young Women ◽  
Case Control Study ◽  
Pesticide Exposure ◽  
Serum Levels ◽  
Case Control ◽  
Incidence Rates ◽  
Younger Women ◽  
Control Study

Abstract Background: Incidence rates of breast cancer are showing an increasing trend in young women (≤40 years) in India. Risk for breast cancer in this age group can be attributed only partially to various known risk factors. Environmental exposure to organochlorine (OC) compounds has been identified as a potential risk factor. However, the possible role of OC compounds in increasing breast cancer risk in young women has not been explored. This case–control study was planned with the objectives to assess the serum levels of OC compound in a North Indian population of young women. Materials and Methods: Forty-two patients of breast cancer ≤ 40 years age and 42 age-matched controls were evaluated for exposure to OC compounds by performing assays in blood samples for pesticides such as dichlorodiphenyltrichloroethane (DDT) and its metabolites DDD and DDE; dieldrin; aldrin; methoxychlor, heptachlor; α-endosulfan; β-endosulfan; and hexachlorocyclohexane and its isomers (α, β, and γ). Results: Young women with breast cancer were found to have significantly higher serum levels of all the OC compounds except aldrin, p, p’ DDT, and methoxychlor. Conclusions: Exposure to OC pesticides could be an important modifiable risk factor for breast cancer, especially in younger women.

A CASE-CONTROL STUDY ON HORMONE THERAPY AS A RISK FACTOR FOR BREAST CANCER IN FINLAND

Maturitas ◽  
2009 ◽  
Vol 63 ◽  
pp. S50 ◽  
Author(s):  
H. Lyytinen ◽  
T. Dyba ◽  
O. Ylikorkala ◽  
E. Pukkala
Keyword(s):  
Breast Cancer ◽  
Risk Factor ◽  
Hormone Therapy ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Dietary fat and breast cancer in Saudi Arabia: a case-control study

2004 ◽  
Vol 10 (6) ◽  
pp. 879-886
Author(s):  
A. Al Othaimeen ◽  
A. Ezzat ◽  
G. Mohamed ◽  
T. Muammar ◽  
A. Al Madouj
Keyword(s):  
Breast Cancer ◽  
Dietary Fat ◽  
Case Control Study ◽  
Saturated Fat ◽  
Positive Association ◽  
Serum Levels ◽  
Case Control ◽  
Serum Triglycerides ◽  
Significant Positive Association ◽  
Control Study

A case-control study investigated the association between dietary fat and breast cancer in Saudi Arabian women attending a specialist hospital in Riyadh. Women with breast carcinoma [n= 499] newly diagnosed between 1996-2002, and control women [n = 498] randomly selected from patients’ attendants and relatives, completed a food frequency questionnaire. Serum levels of triglycerides and total cholesterol were measured. A significant positive association was found between risk of breast cancer and intake of fats, protein and calories. Adjusted odds ratios for the highest quartile of intake versus the lowest were 2.43 for saturated fat, 2.25 for animal protein, 2.12 for polyunsaturated fat, 1.88 for cholesterol and 2.69 for total energy from dietary intake. For serum triglycerides the adjusted odds ratio was 2.16 for the highest quartile

Serum levels of sex hormones and breast cancer risk in premenopausal women: a case–control study (USA)

2004 ◽  
Vol 15 (1) ◽  
pp. 45-53 ◽  
Author(s):  
Susan R. Sturgeon ◽  
Nancy Potischman ◽  
Kathleen E. Malone ◽  
Joanne F. Dorgan ◽  
Janet Daling ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Sex Hormones ◽  
Case Control Study ◽  
Premenopausal Women ◽  
Serum Levels ◽  
Case Control ◽  
Control Study

scholarly journals Breast cancer risk factor evaluation in a Western Himalayan state: A case–control study and comparison with the Western World

2017 ◽  
Vol 06 (03) ◽  
pp. 106-109 ◽  
Author(s):  
Purnima Thakur ◽  
Rajeev Kumar Seam ◽  
Manoj K. Gupta ◽  
Manish Gupta ◽  
Mukesh Sharma ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Risk Factor ◽  
Invasive Breast Cancer ◽  
Case Control Study ◽  
Strong Association ◽  
Breast Cancer Incidence ◽  
Case Control ◽  
Western World ◽  
Control Study

Abstract Context: Breast cancer incidence is increasing rapidly in India. The lifestyle, built, genetic makeup, reproductive and breastfeeding patterns are quite different in Indian females when compared to the Western population. Generalizing the Western data to the population residing in the Himalayan region would breed inaccuracies. Aim: The aim of our study was to identify risk factors in our own population in a Western Himalayan state of Himachal Pradesh, India. Subjects and Methods: A case–control study with 377 cases of invasive breast cancer and 346 hospital-based controls was conducted for 1 year. The data were collected by interviewing the individuals during their visit to hospital using a questionnaire. The data were analyzed using standard statistical techniques using SPSS version 17 software. Results: Factors found to have strong association with invasive breast cancer on multivariate analysis are late age at first childbirth >30 years, which is the strongest risk factor associated, late age of menopause > 50 years, high socioeconomic class, and age of female above 50 years. Conclusion: In our females, age >50 years, late age of menopause (>50 years), late age at first childbirth (>30 years), and high socioeconomic status were found to be major risk factors associated with breast cancer. Several factors implicated in the Western data were not found to be significant in our study. We need to identify such aspects in reproductive and breastfeeding patterns of women and spread awareness regarding the same.

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