scholarly journals Genes expression profiling of alveolar macrophages exposed to non-functionalized, anionic and cationic multi-walled carbon nanotubes shows three different mechanisms of toxicity

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Sara Nahle ◽  
Hilary Cassidy ◽  
Mélanie M. Leroux ◽  
Reuben Mercier ◽  
Jaafar Ghanbaja ◽  
...  
2020 ◽  
Vol V (I) ◽  
pp. 48-57
Author(s):  
Maria Hassan Kiani ◽  
Ayesha Batool ◽  
Maheen Khurshid ◽  
Memoona Kanwal ◽  
Naveed Ahmed

Carbon nanotubes are one of the most widely investigated carbon structures because of variety of physicochemical features offered by them. Their dimensions, surface chemistry and functionalization opportunities make them exceptional carrier for targeted drug delivery gene therapy, diagnosis and cell imaging. Both single and multi-walled CNTs have been functionalized for therapeutic applications. However, these structures have been associated with potential in vitro and in vivo cytotoxic effects. Such toxicities have been described to involve both cellular and subcellular mechanisms. Major organs that have shown significant CNTs related toxic effects include lungs, brain, heart, kidney, liver and skin. This review focuses on the potential toxicological effects of single and multi-walled carbon nanotubes and functionalization on these organs and associated mechanisms of toxicity


Acta Naturae ◽  
2011 ◽  
Vol 3 (1) ◽  
pp. 99-106 ◽  
Author(s):  
E A Smirnova ◽  
A A Gusev ◽  
O N Zaitseva ◽  
E M Lazareva ◽  
G E Onishchenko ◽  
...  

2003 ◽  
Vol 772 ◽  
Author(s):  
T. Seeger ◽  
G. de la Fuente ◽  
W.K. Maser ◽  
A.M. Benito ◽  
A. Righi ◽  
...  

AbstractCarbon nanotubes (CNT) are interesting candidates for the reinforcement in robust composites and for conducting fillers in polymers due to their fascinating electronic and mechanical properties. For the first time, we report the incorporation of multi walled carbon nanotubes (MWNTs) into silica-glass surfaces by means of partial surface-melting caused by a continuous wave Nd:YAG laser. MWNTs were detected being well incorporated in the silica-surface. The composites are characterized using scanning electron microscopy (SEM) and Raman-spectroscopy. A model for the composite-formation is proposed based on heatabsorption by MWNTs and a partial melting of the silica-surface.


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