scholarly journals Age-related differences in working hours among male and female GPs: an SMS-based time use study

2017 ◽  
Vol 15 (1) ◽  
Author(s):  
Daniël van Hassel ◽  
Lud van der Velden ◽  
Dinny de Bakker ◽  
Ronald Batenburg
1985 ◽  
Vol 17 (2) ◽  
pp. 115-130 ◽  
Author(s):  
ROBERT J. BURSIK ◽  
DON MERTEN ◽  
GARY SCHWARTZ

2005 ◽  
Vol 38 (2) ◽  
pp. 245-256 ◽  
Author(s):  
L WILLEMS ◽  
A ZATTA ◽  
K HOLMGREN ◽  
K ASHTON ◽  
J HEADRICK

2018 ◽  
Vol 75 (6) ◽  
pp. 1042-1049
Author(s):  
Seongjoon Park ◽  
Erkhembayar Nayantai ◽  
Toshimitsu Komatsu ◽  
Hiroko Hayashi ◽  
Ryoichi Mori ◽  
...  

Abstract The orexigenic hormone neuropeptide Y (NPY) plays a pivotal role in the peripheral regulation of fat metabolism. However, the mechanisms underlying the effects of sex on NPY function have not been extensively analyzed. In this study, we examined the effects of NPY deficiency on fat metabolism in male and female mice. Body weight was slightly decreased, whereas white adipose tissue (WAT) mass was significantly decreased as the thermogenic program was upregulated in NPY-/- female mice compared with that in wild-type mice; these factors were not altered in response to NPY deficiency in male mice. Moreover, lack of NPY resulted in an increase in luteinizing hormone (LH) expression in the pituitary gland, with concomitant activation of the estradiol-mediated thermogenic program in inguinal WAT, and alleviated age-related modification of adiposity in female mice. Taken together, these data revealed a novel intracellular mechanism of NPY in the regulation of fat metabolism and highlighted the sexual dimorphism of NPY as a promising target for drug development to reduce postmenopausal adiposity.


Author(s):  
Jazmin A Cole ◽  
Mackenzie N Kehmeier ◽  
Bradley R Bedell ◽  
Sahana Krishna Kumaran ◽  
Grant D Henson ◽  
...  

Abstract Vascular endothelial function declines with age on average, but there is high variability in the magnitude of this decline within populations. Measurements of frailty, known as frailty index (FI), can be used as surrogates for biological age, but it is unknown if frailty relates to the age-related decline in vascular function. To examine this relation, we studied young (4-9 months) and old (23-32 months) C57BL6 mice of both sexes. We found that FI was greater in old compared with young mice, but did not differ between old male and female mice. Middle cerebral artery (MCA) and mesenteric artery endothelium-dependent dilation (EDD) also did not differ between old male and female mice; however, there were sex differences in the relations between FI and EDD. For the MCA, FI was inversely related to EDD among old female mice, but not old male mice. In contrast, for the mesenteric artery, FI was inversely related to EDD among old male mice, but not old female mice. A higher FI was related to a greater improvement in EDD with the superoxide scavenger TEMPOL in the MCAs for old female mice and in the mesenteric arteries for old male mice. FI related to mesenteric artery gene expression negatively for extracellular superoxide dismutase (Sod3) and positively for interleukin-1β (Il1b). In summary, we found that the relation between frailty and endothelial function is dependent on sex and the artery examined. Arterial oxidative stress and pro-inflammatory signaling are potential mediators of the relations of frailty and endothelial function.


1996 ◽  
Vol 8 (3) ◽  
pp. 465 ◽  
Author(s):  
Gandarias JM de ◽  
J Irazusta ◽  
E Echevarria ◽  
J Gil ◽  
L Casis

It has been recently suggested that enkephalins might play a normal role in the regulation of cellular development in brain. Since the major pathway of enkephalin degradation seems to occur under the action of aminopeptidases, in the present paper we describe the changes in Tyr-aminopeptidase activities during several stages of the rat (male and female) brain development (9, 12, 15, 20 and 25 days postbirth). The enzyme activities (soluble and membrane-bound) were detected using Tyr-2-naphthylamide as substrate. No sexual differences were observed. However, significant rises from the 9th to the 15th postnatal day in the soluble peptidase activity were appreciated. Aminopeptidase M shows decreases in the activity with age. It is suggested that not only the enkephalins but also the enkephalin-degrading enzymes could play a part in the maturation of the rat brain.


2019 ◽  
Vol 11 (11) ◽  
pp. 3067 ◽  
Author(s):  
Eva Thulin ◽  
Bertil Vilhelmson ◽  
Martina Johansson

This study explores how changing conditions for home-based telework affect the quality of life and social sustainability of workers in terms of time pressure and time use control in everyday life. Changing conditions concern the spread of telework to new types of jobs of a more routine character, involving new practices of unregulated work and anytime smartphone access. Empirically, we draw on survey data from a sample of 456 home-based teleworkers employed by six governmental agencies in Sweden. Results indicate that subjective time pressure is not associated with job type in terms of distinguishing between bounded case work and more independent analytical work. Time pressure is intensified by family-related factors, telework performed outside of working hours, and part-time work, and is moderated by the private use of smartphones. We find no significant associations between subjective time use control, job qualifications, and teleworking practice. Family situation and having small children at home reduce time use control. Also, high levels of smartphone use for work-related purposes are associated with reduced control.


2020 ◽  
Vol 45 (4) ◽  
pp. 393-410
Author(s):  
Magdalena Rokicka ◽  
Olga Zajkowska

Abstract This paper examines the risk of time poverty defined as leisure participation among informal caregivers of adults and older people. We draw on the most recent time use survey conducted in Poland, which incorporated more than 28,000 households in 2013. We assess the extent to which caregivers are more likely to experience shortages of time spent on physical activity, hobbies, and social life. Additional information about respondents’ time preferences allows us to examine not only the objective and relative time deficits of caregivers, but also the subjective and expressed ones. We distinguish between co-resident caregivers and those living outside the household of care recipients, simultaneously accounting for the differences between male and female caregivers, as well as care provided during working days (Monday-Friday), and that provided on weekends (Saturday-Sunday). Our results indicate that caregivers for adults are in general more likely to allocate less time to physical activity, hobbies, and their social lives. This effect, however, is observed primarily among co-resident caregivers, both male and female. The leisure time of caregivers is more noticeably affected during weekends than on working days. Concurrently, caregivers are more likely to admit that they wish to spend more time on different forms of leisure activity. This confirms the hypothesis of a trade-off between time allocated to elderly care and that allocated to self-care, which can be detrimental to the health, life satisfaction, and wellbeing of informal caregivers.


1997 ◽  
Vol 1607 (1) ◽  
pp. 134-138 ◽  
Author(s):  
Paul van Beek ◽  
Nelly Kalfs ◽  
Ursula Blom

As in many other countries, a growing number of women in the Netherlands are entering the labor market. The difference between male and female participation in paid work is decreasing, and more men are taking care of domestic duties. It is expected that these changes will lead to growing numbers of task combiners and to more similar patterns of travel behavior for men and women. The intention of the present research is to investigate these expectations for the situation in the Netherlands. For this goal two groups of time budget data for the period from 1975 to 1990 were analyzed. The focus was on gender differences in trends in time use and mobility. The results indicate that between 1975 and 1990, the distribution of paid work and domestic work by men and women changed, more men and women were performing combinations of obligatory tasks, gender differences in mobility became smaller, and car use, both for men and for women, depended heavily on the workload of an out-of-home paid job.


2018 ◽  
Vol 19 (3) ◽  
Author(s):  
Timothy P. O'Leary ◽  
Hector M. Mantolino ◽  
Kurt R. Stover ◽  
Richard E. Brown

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