scholarly journals Mapping the baseline prevalence of lymphatic filariasis across Nigeria

2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Obiora A. Eneanya ◽  
Claudio Fronterre ◽  
Ifeoma Anagbogu ◽  
Chukwu Okoronkwo ◽  
Tini Garske ◽  
...  

Abstract Introduction The baseline endemicity profile of lymphatic filariasis (LF) is a key benchmark for planning control programmes, monitoring their impact on transmission and assessing the feasibility of achieving elimination. Presented in this work is the modelled serological and parasitological prevalence of LF prior to the scale-up of mass drug administration (MDA) in Nigeria using a machine learning based approach. Methods LF prevalence data generated by the Nigeria Lymphatic Filariasis Control Programme during country-wide mapping surveys conducted between 2000 and 2013 were used to build the models. The dataset comprised of 1103 community-level surveys based on the detection of filarial antigenemia using rapid immunochromatographic card tests (ICT) and 184 prevalence surveys testing for the presence of microfilaria (Mf) in blood. Using a suite of climate and environmental continuous gridded variables and compiled site-level prevalence data, a quantile regression forest (QRF) model was fitted for both antigenemia and microfilaraemia LF prevalence. Model predictions were projected across a continuous 5 × 5 km gridded map of Nigeria. The number of individuals potentially infected by LF prior to MDA interventions was subsequently estimated. Results Maps presented predict a heterogeneous distribution of LF antigenemia and microfilaraemia in Nigeria. The North-Central, North-West, and South-East regions displayed the highest predicted LF seroprevalence, whereas predicted Mf prevalence was highest in the southern regions. Overall, 8.7 million and 3.3 million infections were predicted for ICT and Mf, respectively. Conclusions QRF is a machine learning-based algorithm capable of handling high-dimensional data and fitting complex relationships between response and predictor variables. Our models provide a benchmark through which the progress of ongoing LF control efforts can be monitored.

1998 ◽  
Vol 38 (3) ◽  
pp. 7-14
Author(s):  
A. J. Dunn ◽  
D. A. Frodsham ◽  
R. V. Kilroy

The privatised water industry in England and Wales has the requirement to construct a substantial number of new assets to meet new national and European legislation. In order to do so economically, the risk of performance of new assets has to be matched to the cost of construction. To undertake such risk management, a risk technique has been developed that allows the performance against permit compliance of new processes to be established. The technique is based on statistical analysis of data effectively creating a pure black box model to determine performance. The technique has been further developed to take into account the dependency between influent quality and process performance. The dependency factor selected is the Spearman's Rank Coefficient which is a convenient way to define complex relationships. It can be used to define many dependent variables referring to the same independent variable and as such removes the need for complex mechanistic equations. This technique has been calibrated using two years, existing data and then validated for the next 6 months data of a wastewater treatment works in the North West of England. The results of the validation illustrate the ability of the technique to be used as a predictive tool. The output from the model allows the direct comparison of different process options and permits executive management to make informed decisions about investment against risk to permit compliance.


Author(s):  
Daryl A. Cornish ◽  
George L. Smit

Oreochromis mossambicus is currently receiving much attention as a candidater species for aquaculture programs within Southern Africa. This has stimulated interest in its breeding cycle as well as the morphological characteristics of the gonads. Limited information is available on SEM and TEM observations of the male gonads. It is known that the testis of O. mossambicus is a paired, intra-abdominal structure of the lobular type, although further details of its characteristics are not known. Current investigations have shown that spermatids reach full maturity some two months after the female becomes gravid. Throughout the year, the testes contain spermatids at various stages of development although spermiogenesis appears to be maximal during November when spawning occurs. This paper describes the morphological and ultrastructural characteristics of the testes and spermatids.Specimens of this fish were collected at Syferkuil Dam, 8 km north- west of the University of the North over a twelve month period, sacrificed and the testes excised.


2014 ◽  
Author(s):  
Roald Amundsen ◽  
Godfred Hansen
Keyword(s):  

2003 ◽  
pp. 136-146
Author(s):  
K. Liuhto

Statistical data on reserves, production and exports of Russian oil are provided in the article. The author pays special attention to the expansion of opportunities of sea oil transportation by construction of new oil terminals in the North-West of the country and first of all the largest terminal in Murmansk. In his opinion, one of the main problems in this sphere is prevention of ecological accidents in the process of oil transportation through the Baltic sea ports.


Author(s):  
Angelina E. Shatalova ◽  
Uriy A. Kublitsky ◽  
Dmitry A. Subetto ◽  
Anna V. Ludikova ◽  
Alar Rosentau ◽  
...  

The study of paleogeography of lakes is an actual and important direction in modern science. As part of the study of lakes in the North-West of the Karelian Isthmus, this analysis will establish the dynamics of salinity of objects, which will allow to reconstruct changes in the level of the Baltic Sea in the Holocene.


Author(s):  
Eleonora P. Radionova

The associations and ecological conditions of the existence of modern diatoms of the North-West (Pridneprovsky), Prikerchensky and Eastern regions of the subtidal zone of the Black Sea are considered. Based on the unity of the composition of the Present and Sarmatian-Meotian diatom flora, an attempt has been made to model some of the ecological c situation of the Late Miocene Euxinian basin.


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