scholarly journals Associations between social and intellectual activities with cognitive trajectories in Chinese middle-aged and older adults: a nationally representative cohort study

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Haibin Li ◽  
Changwei Li ◽  
Anxin Wang ◽  
Yanling Qi ◽  
Wei Feng ◽  
...  
Keyword(s):  
Older Adults ◽  
Longitudinal Study ◽  
Cognitive Function ◽  
Cognitive Aging ◽  
Multinomial Logistic Regression ◽  
Middle Aged ◽  
Cognitive Assessments ◽  
Visuospatial Skills ◽  
Nationally Representative ◽  
Intellectual Activities

Abstract Background Associations between the frequency of social and intellectual activities and cognitive trajectories are understudied in Chinese middle-aged and older adults. We aimed to examine this association in a nationally representative longitudinal study. Methods The China Health and Retirement Longitudinal Study (CHARLS) is a nationally representative sample of Chinese middle-aged and older participants. The frequency of social and intellectual activities was measured at baseline. Interview-based cognitive assessments of orientation and attention, episodic memory, and visuospatial skills and the calculation of combined global scores were assessed every 2 years from 2011 to 2016. Cognitive aging trajectories over time were analyzed using group-based trajectory modeling, and the associations of the trajectory memberships with social and intellectual activities were analyzed using multinomial logistic regression. Odds ratios (OR) and 95% confidence intervals (CI) were reported. Results Among 8204 participants aged 50–75 years at baseline, trajectory analysis identified three longitudinal patterns of cognitive function based on the global cognitive scores: “persistently low trajectory” (n = 1550, 18.9%), “persistently moderate trajectory” (n = 3194, 38.9%), and “persistently high trajectory” (n = 3460, 42.2%). After adjustment for sociodemographic variables, lifestyles, geriatric symptoms, and health conditions, more frequent intellectual activities (OR 0.54, 95% CI 0.38–0.77) and social activities (OR 0.79, 95% CI 0.65–0.95) were both associated with a lower likelihood of being in the “persistently low trajectory” for global cognitive function. Conclusions These findings suggested that more frequent social and intellectual activities were associated with more favorable cognitive aging trajectories.

scholarly journals Associations between social and intellectual activities with cognitive trajectories in Chinese middle-aged and older adults: a nationally representative cohort study

2020 ◽  
Author(s):  
Haibin Li ◽  
Changwei Li ◽  
Anxin Wang ◽  
Yanling Qi ◽  
Wei Feng ◽  
...  
Keyword(s):  
Older Adults ◽  
Longitudinal Study ◽  
Cognitive Aging ◽  
Multinomial Logistic Regression ◽  
Middle Aged ◽  
Cognitive Assessments ◽  
Visuospatial Skills ◽  
Nationally Representative ◽  
Intellectual Activities ◽  
Representative Cohort

Abstract Background: Associations between the frequency of social and intellectual activities and cognitive trajectories are understudied in Chinese middle-aged and older adults. We aimed to examine this association in a nationally representative longitudinal study. Methods: The China Health and Retirement Longitudinal Study (CHARLS) is a nationally representative sample of Chinese middle-aged and older participants. The frequency of social and intellectual activities was measured at baseline. Interview-based cognitive assessments of orientation and attention, episodic memory, and visuospatial skills and the calculation of combined global scores were assessed every 2 year. Cognitive trajectories over the study period were analyzed using group-based trajectory model , and the associations of the trajectory memberships with social and intellectual activities were analyzed using multinomial logistic regression. Odd ratios (OR) and 95% confidence intervals (CI) were reported. Results: Among 8204 participants aged 50-75 years, trajectory analysis identified three longitudinal patterns of cognitive function based on the global cognitive scores: “ persistently low ” (n = 1550, 18.9%); “persistently moderate” (n = 3194, 38.9%); and “persistently high” (n = 3460, 42.2%). After adjustment for sociodemographic variables, lifestyles, geriatric symptoms and health conditions, more frequent intellectual activities (OR: 0.54, 95% CI: 0.38-0.77) and social activities (OR: 0.79, 95% CI: 0.65-0.95) were both associated with a lower likelihood of being in the “persistently low” global cognitive trajectory group. Conclusions: More frequent social and intellectual activities were associated with more favorable cognitive aging trajectories.

scholarly journals Associations between social and intellectual activities with cognitive trajectories in Chinese middle-aged and older adults: a nationally representative cohort study

2020 ◽  
Author(s):  
Haibin Li ◽  
Changwei Li ◽  
Anxin Wang ◽  
Yanling Qi ◽  
Wei Feng ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Aging ◽  
Trajectory Analysis ◽  
Multinomial Logistic Regression ◽  
Middle Aged ◽  
Cognitive Assessments ◽  
Visuospatial Skills ◽  
Nationally Representative ◽  
Intellectual Activities ◽  
Representative Cohort

Abstract Background: Associations between the frequency of social and intellectual activities and cognitive trajectories are understudied in Chinese middle-aged and older adults. We aimed to examine this association in a nationally representative longitudinal study.Methods: The China Health and Retirement Longitudinal Study (CHARLS) is a nationally representative sample of Chinese middle-aged and older participants. The frequency of social and intellectual activities was measured at baseline. Interview-based cognitive assessments of orientation and attention, episodic memory, and visuospatial skills and the calculation of combined global scores were assessed every 2 year from 2011 to 2016. Cognitive trajectories over the study period were analyzed using group-based trajectory model, and the associations of the trajectory memberships with social and intellectual activities were analyzed using multinomial logistic regression. Odd ratios (OR) and 95% confidence intervals (CI) were reported.Results: Among 8204 participants aged 50-75 years, trajectory analysis identified three longitudinal patterns of cognitive function based on the global cognitive scores: “persistently low trajectory” (n = 1550, 18.9%); “persistently moderate trajectory” (n = 3194, 38.9%); and “persistently high trajectory” (n = 3460, 42.2%). After adjustment for sociodemographic variables, lifestyles, geriatric symptoms and health conditions, more frequent intellectual activities (OR: 0.54, 95% CI: 0.38-0.77) and social activities (OR: 0.79, 95% CI: 0.65-0.95) were both associated with a lower likelihood of being in the “persistently low trajectory” for global cognitive function.Conclusions: These findings suggested that more frequent social and intellectual activities were associated with more favorable cognitive aging trajectories.

scholarly journals Associations between social and intellectual activities with cognitive trajectories in Chinese middle-aged and older adults: a nationally representative cohort study

2019 ◽  
Author(s):  
Haibin Li ◽  
Changwei Li ◽  
Anxin Wang ◽  
Wei Feng ◽  
Chengbei Hou ◽  
...  
Keyword(s):  
Older Adults ◽  
Cohort Study ◽  
Cognitive Aging ◽  
Multinomial Logistic Regression ◽  
Middle Aged ◽  
Cognitive Assessments ◽  
Visuospatial Skills ◽  
Trajectory Group ◽  
Nationally Representative ◽  
Intellectual Activities

Abstract Background Associations between the frequency of social and intellectual activities and cognitive trajectories are understudied in Chinese middle-aged and older adults. We aimed to examine this association in a nationally representative longitudinal study.Methods The China Health and Retirement Longitudinal Study (CHARLS) is a prospective cohort study conducted from 2011 to 2016, with a nationally representative sample of Chinese middle-aged and older participants. The frequency of social and intellectual activities was measured in 2011-2012. Interview-based cognitive assessments of orientation and attention, episodic memory, and visuospatial skills and the calculation of combined global scores were conducted in three waves (2011-2012, 2013-2014 and 2015-2016). Cognitive trajectories over the study period were analyzed using group-based trajectory models (GBTMs), and the associations of the trajectory memberships with social and intellectual activities were analyzed using multinomial logistic regression. Odds ratios (ORs) and 95% confidence intervals (CIs) were reported.Results After excluding respondents with missing data on cognitive function, we ultimately included 7243 participants aged 50 years or older in the analysis. Three trajectory groups for global cognitive performance over time were identified: low (20.34%), intermediate (34.39%) and high (45.27%). After adjustment for sociodemographic variables, lifestyles and health conditions, more frequent intellectual activities (OR: 0.43, 95% CI: 0.32 - 0.58) and social activities (OR: 0.66, 95% CI: 0.56 - 0.78) were both associated with a lower likelihood of being in the low global cognitive trajectory group than in the high trajectory group in separate analyses. These associations persisted after mutually exclusive adjustment for social and intellectual activities.Conclusions More frequent social and intellectual activities were associated with more favorable cognitive aging trajectories. Increasing the frequency of engagement in social and intellectual activities might help delay or prevent cognitive impairment in older people.

scholarly journals RECIPROCAL RELATIONSHIP BETWEEN COGNITION AND EDENTULISM AMONG MIDDLE-AGED AND OLDER ADULTS IN CHINA

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S350-S350
Author(s):  
Nan Lu ◽  
Bei Wu ◽  
Yaolin Pei
Keyword(s):  
Older Adults ◽  
Longitudinal Study ◽  
Oral Health ◽  
Cognitive Function ◽  
Empirical Evidence ◽  
Tooth Loss ◽  
Reciprocal Relationship ◽  
Middle Aged ◽  
Cognitive Health

Abstract While empirical evidence shows that cognitive function affects oral health and vice versa, there is a lack of empirical evidence to test the reciprocal relationship between these two indicators. This study aimed to examine this relationship among middle-aged and older adults in China. Data were derived from the 2011 and 2015 waves of the China Health and Retirement Longitudinal study. A two-wave cross-lag analysis was adopted to test the hypothesized model. Cognitive function in 2011 was found to be a significant predictor of complete tooth loss in 2015. Furthermore, complete tooth loss in 2011 was found to be a significant predictor of cognitive cognition in 2015. This finding demonstrates the reciprocal relationship between cognitive function and oral health. This study highlights the importance of improving both cognitive health and oral health for middle-aged and older adults. Policy and intervention implications are discussed.

scholarly journals Exploring the reciprocal relationship between cognitive function and edentulism among middle-aged and older adults in China

2020 ◽  
Author(s):  
Nan Lu ◽  
Bei Wu ◽  
Yaolin Pei
Keyword(s):  
Older Adults ◽  
Developing Countries ◽  
Longitudinal Study ◽  
Oral Health ◽  
Cognitive Function ◽  
Age Groups ◽  
Reciprocal Relationship ◽  
Middle Aged ◽  
Reciprocal Relationships

Abstract Objective Previous longitudinal studies have found that cognitive function affected oral health, and vice versa. However, research is lacking on the reciprocal relationships between cognitive function and edentulism simultaneously, especially in developing countries. The present study aimed to examine the reciprocal relationship between cognitive function and edentulism among middle-aged and older adults in China. Methods Data were derived from the 2011 and 2015 waves of the China Health and Retirement Longitudinal Study. The sample included 14,038 respondents aged 45 or older. A two-wave cross-lagged analysis was adopted to test the hypothesized model. Results Among respondents aged 45–59, baseline cognitive function was associated with subsequent edentulism [b = −0.017, standard deviation (SD) = 0.006, P < 0.01]. In contrast, baseline edentulism was not significantly associated with poorer cognitive function at the follow-up wave (b = −0.744, SD = 0.383, P > 0.05). However, among respondents aged 60 or older, baseline cognitive function was associated with subsequent edentulism (b = −0.017, SD = 0.005, P < 0.01), and baseline edentulism was also associated with follow-up lower levels of cognitive function (b = −0.419, SD = 0.143, P < 0.01). Conclusions These findings demonstrated the reciprocal relationships of cognitive function and edentulism. However, such relationships varied across age groups. This study demonstrates the importance of developing programs and services to promote both cognitive and oral health, especially for those in older age.

scholarly journals Social engagement and cognitive function among middle-aged and older adults: gender-specific findings from the Korean longitudinal study of aging (2008–2018)

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sarah Soyeon Oh ◽  
Eunhee Cho ◽  
Bada Kang
Keyword(s):  
Older Adults ◽  
Longitudinal Study ◽  
Cognitive Function ◽  
Social Engagement ◽  
Social Activity ◽  
Later Life ◽  
Estimating Equation ◽  
Senior Center ◽  
Middle Aged ◽  
Gender Specific

AbstractRecent findings suggest that social disengagement in later life may result in cognitive decline and increase risk of Alzheimer’s and related dementias. However, little is known regarding the gender-specific longitudinal association between social engagement and cognition among middle-aged and older adults. Using data from a nationally representative sample of 2707 men and 5196 women from the Korean longitudinal study of aging, we examined the gender-specific association between social activity and cognitive function. Results from the generalized estimating equation model showed that compared to individuals with consistent social engagement (religious, senior center, sport, reunion, voluntary, political), individuals with inconsistent engagement had lower cognitive function. Transitioning from engagement to non-engagement was associated with lower cognitive function among men only. Not being part of a senior center was associated with decreased cognitive function among both genders, while not being part of a religious group was significant for women only. While marital status was a significant predictor of cognitive ability for women, depression was a significant predictor for men. These findings have implications for policy-makers as interventions targeting improved cognitive function among middle-aged and older adults may be more effective when gender-specific predictors are taken into consideration.

Visual Memory Deficits in Middle-Aged APOE ɛ4 Homozygotes Detected Using Unsupervised Cognitive Assessments

2021 ◽  
Vol 79 (4) ◽  
pp. 1563-1573
Author(s):  
Yen Ying Lim ◽  
Matthew P. Pase ◽  
Rachel F. Buckley ◽  
Nawaf Yassi ◽  
Lisa Bransby ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Function ◽  
Visual Memory ◽  
Memory Impairment ◽  
Saliva Sample ◽  
Imaging Biomarkers ◽  
Middle Aged ◽  
Cognitive Assessments ◽  
Subjective Cognitive Function ◽  
Middle Aged Adults

Background: The apolipoprotein E (APOE) ɛ4 allele is associated with dose-response effects on cognitive dysfunction and dementia risk in older adults. However, its effects on cognition in middle-aged adults remains unclear. Objective: We examined effects of ɛ4 heterozygosity and homozygosity on objective and subjective cognition in middle-aged adults enrolled in the Healthy Brain Project (HBP) and in older adults from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study. Methods: HBP participants (1,000 non-carriers; 450 ɛ4 heterozygotes; 50 ɛ4 homozygotes) completed unsupervised assessments of the Cogstate Brief Battery (CBB), ratings of subjective cognitive function and provided a saliva sample. AIBL cognitively normal participants (650 non-carriers; 204 ɛ4 heterozygotes; 31 ɛ4 homozygotes) completed in-person assessments of the CBB, ratings of subjective cognitive function and provided a blood sample. Results: Greater memory impairment was observed in middle-aged ɛ4 homozygotes compared with ɛ4 heterozygotes and non-carriers. When data from middle-aged (HBP) and older (AIBL) adults were pooled, the effect of ɛ4 homozygosity and memory impairment increased with age. In both middle-aged and older adults, ɛ4 heterozygotes did not differ from non-carriers on any measure of objective or subjective cognition. Conclusion: Memory impairment in ɛ4 homozygotes is evident in adults aged 50-60 years, and this can be detected through unsupervised cognitive assessments. The effect of ɛ4 homozygosity increases with older age. APOE ɛ4 homozygosity has a negative impact on memory as early as midlife, but due to the subtle magnitude of effect, our findings support the necessity of online platforms in large cohorts to assess these complex relationships.

scholarly journals Social isolation, rather than loneliness, is associated with cognitive decline in older adults: the China Health and Retirement Longitudinal Study

2021 ◽  
pp. 1-8
Author(s):  
Bin Yu ◽  
Andrew Steptoe ◽  
Yongjie Chen ◽  
Xiaohua Jia
Keyword(s):  
Older Adults ◽  
Longitudinal Study ◽  
Cognitive Function ◽  
Episodic Memory ◽  
Cognitive Decline ◽  
Social Isolation ◽  
Mental Status ◽  
Chinese Older Adults ◽  
Confounding Variables

Abstract Background Social isolation and loneliness have each been associated with cognitive decline, but most previous research is limited to Western populations. This study examined the relationships of social isolation and loneliness on cognitive function among Chinese older adults. Methods This study used two waves of data (2011 and 2015) from the China Health and Retirement Longitudinal Study and analyses were restricted to those respondents aged 50 and older. Social isolation, loneliness, and cognitive function were measured at baseline. Follow-up measures on cognitive function were obtained for 7761 participants (mean age = 60.97, s.d. = 7.31; male, 50.8%). Lagged dependent variable models adjusted for confounding factors were used to evaluate the association between baseline isolation, loneliness, and cognitive function at follow-up. Results Loneliness was significantly associated with the cognitive decline at follow-up (episodic memory: β = −0.03, p < 0.01; mental status: β = −0.03, p < 0.01) in the partially adjusted models. These associations became insignificant after additional confounding variables (chronic diseases, health behaviors, disabilities, and depressive symptoms) were taken into account (all p > 0.05). By contrast, social isolation was significantly associated with decreases in all cognitive function measures at follow-up (episodic memory: β = −0.05, p < 0.001; mental status: β = −0.03, p < 0.01) even after controlling for loneliness and all confounding variables. Conclusions Social isolation is associated with cognitive decline in Chinese older adults, and the relationships are independent of loneliness. These findings expand our knowledge about the links between social relationships and the cognitive function in non-Western populations.

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