scholarly journals Ethnomedical uses, chemical constituents, and evidence-based pharmacological properties of Chenopodium ambrosioides L.: extensive overview

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Félicien Mushagalusa Kasali ◽  
Jonans Tusiimire ◽  
Justin Ntokamunda Kadima ◽  
Amon Ganafa Agaba
Keyword(s):  
Large Scale ◽  
Chemical Constituents ◽  
Main Body ◽  
Pharmacological Properties ◽  
Chenopodium Ambrosioides ◽  
Traditional Medicines ◽  
Plant Parts ◽  
Chemical Studies ◽  
Ethnomedicinal Uses ◽  
Significant Health

Abstract Background The Chenopodium genus is a plant family widely spread worldwide that includes various plant species reputed to possess several medicinal virtues in folk medicines. Chenopodium ambrosioides L. is among the most used plants in traditional medicines worldwide. This review aimed to highlight ethnomedicinal uses, phytochemical status, and pharmacological properties of C. ambrosioides L. Main body of the abstract The analysis of relevant data highlights various ethnomedicinal uses against human and veterinary diseases in forty countries. Most indications consisted of gastrointestinal tract dysfunctioning troubles and worms parasitemia. Around 330 chemical compounds have been identified in different plant parts, especially in its essential oil fractions (59.84%). However, only a few compounds—mainly monoterpenes and glycosides—have been isolated and characterized. Experimental pharmacological studies validated a large scale of significant health benefits. It appeared that many monoterpenes are antioxidant, insecticidal, trypanocidal, analgesic, antifungal, anti-inflammatory, anti-arthritic, acaricidal, amoebicidal, anthelmintic, anticancer, antibacterial, antidiabetic, antidiarrheal, antifertility, antifungal, anti-leishmanial, antimalarial, antipyretic, antisickling, antischistosomal, antiulcer, anxiolytic, immunomodulatory, molluscicidal, and vasorelaxant agents. Short conclusion Thus, the Chenopodium ambrosioides species necessitates further chemical studies to isolate and characterize new bioactive secondary metabolites and pharmacological investigations to precise the mechanisms of action before clinical trials.

scholarly journals Maerua juncea Pax and M. schinzii Pax (Capparaceae): A comparative analysis of their ethnobotany and ethnomedicinal uses

2020 ◽  
Vol 11 (4) ◽  
pp. 6017-6022
Author(s):  
Alfred Maroyi
Keyword(s):  
Leaf Extracts ◽  
Scientific Publications ◽  
Respiratory Problems ◽  
Traditional Medicines ◽  
Plant Parts ◽  
Online Databases ◽  
Toxicological Studies ◽  
History Of ◽  
Cytotoxicity Activities ◽  
Ethnomedicinal Uses

Maerua juncea Pax and M. schinzii Pax have a long history of medicinal use in southern Africa. This study aimed to review the ethnomedicinal uses, phytochemistry and pharmacological properties of the two species. Results of this study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. The leaves, roots, stems or whole plant parts of M. juncea and M. schinzii are mainly used as protective charm and tonic, and traditional medicines for fever, heart problems, headache, earache, skin disorders, fatigue and respiratory problems. This study showed that betaines and quaternary ammonium compounds such as 3-hydroxyprolinebetaine, proline betaine and 3-hydroxy-1,1-dimethyl pyrrolidinium had been identified from the aerial parts of M. juncea. In contrast, alkaloids, bitter principles, coumarins, flavonoids, saponins and terpenes have been identified from the leaves of M. schinzii. The leaf extracts and compounds isolated from the species exhibited antibacterial, antifungal, anti-HIV and cytotoxicity activities. There is a need for extensive phytochemical, pharmacological and toxicological studies of crude extracts of M. juncea and M. schinzii to establish the safety profiles of different preparations of the two species.

scholarly journals Clinacanthus nutans: a review on ethnomedicinal uses, chemical constituents and pharmacological properties

2017 ◽  
Vol 55 (1) ◽  
pp. 1093-1113 ◽  
Author(s):  
Ihsan N. Zulkipli ◽  
Rajan Rajabalaya ◽  
Adi Idris ◽  
Nurul Atiqah Sulaiman ◽  
Sheba R. David
Keyword(s):  
Chemical Constituents ◽  
Pharmacological Properties ◽  
Clinacanthus Nutans ◽  
Ethnomedicinal Uses

scholarly journals AEGLE MARMELOS (BAEL PATRA): AN AYURVEDIC PLANT WITH ETHNOMEDICINAL VALUE

2021 ◽  
Vol 12 (3) ◽  
pp. 147-156
Author(s):  
Shailja Choudhary ◽  
Gitika Chaudhary ◽  
Hemlata Kaurav
Keyword(s):  
Skin Diseases ◽  
Review Article ◽  
Pharmacological Properties ◽  
Healing Ulcer ◽  
Aegle Marmelos ◽  
Unripe Fruit ◽  
Plant Parts ◽  
Medicinal Value ◽  
Hindu Temples ◽  
Ethnomedicinal Uses

Aegle marmelos is considered as the most sacred or holy plant which is grown by the sides of Hindu temples. This plant is dedicated to Lord Shiva and is also believed that Lord Shiva resides under the Bael tree. Besides this, the plant is associated with a great medicinal value whose medicinal description is also mentioned in the ancient treatise like Vedas, Puranas, Charaka Samhita and Brihat Samhita and has also been portrayed in the paintings of Ajanta caves. Every part of the Bael plant is used to treat various diseases. In Ayurveda, the plant is used in Panchang form to treat diarrhea, dysentery and ulcer. In folklore, the plant parts are used to treat diabetes, skin diseases and typhoid, wound healing, ulcer, stomachache, jaundice, high BP, malaria, cancer and other diseases. The fruit of the plant is edible and carries great medicinal value because of the presence of vitamins, minerals and various antioxidants. The pulp of the fruit is aromatic, sweet, pale orange and resinous. The unripe fruit pulp of the plant is used to prepare murabba, pudding and juice. The plant is associated with ethnomedicinal uses and possesses various therapeutic and pharmacological properties including antioxidant, anti-diabetic, antihistamine, radio protective, antiulcer, anticancer, cardio-protective, antidiarrheal, antibacterial, antimicrobial, hepatoprotective, anti-inflammatory and antiviral. In this review article, attempts have been made to summarize the phytochemistry, ethnomedicinal, Ayurvedic and pharmacological view of the Bael plant.

scholarly journals A Review of the Ethnomedicinal Uses, Biological Activities, and Triterpenoids of Euphorbia Species

Molecules ◽  
2020 ◽  
Vol 25 (17) ◽  
pp. 4019
Author(s):  
Douglas Kemboi ◽  
Xolani Peter ◽  
Moses Langat ◽  
Jacqueline Tembu
Keyword(s):  
Drug Discovery ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Structural Diversity ◽  
Pharmacological Properties ◽  
Anticancer Activities ◽  
Sensory Disorders ◽  
Wide Range ◽  
Ethnomedicinal Uses

The genus Euphorbia is one of the largest genera in the spurge family, with diversity in range, distribution, and morphology. The plant species in this genus are widely used in traditional medicine for the treatment of diseases, ranging from respirational infections, body and skin irritations, digestion complaints, inflammatory infections, body pain, microbial illness, snake or scorpion bites, pregnancy, as well as sensory disorders. Their successes have been attributed to the presence of diverse phytochemicals like polycyclic and macrocyclic diterpenes with various pharmacological properties. As a result, Euphorbia diterpenes are of interest to chemists and biochemists with regard to drug discovery from natural products due to their diverse therapeutic applications as well as their great structural diversity. Other chemical constituents such as triterpenoids have also been reported to possess various pharmacological properties, thus supporting the traditional uses of the Euphorbia species. These triterpenoids can provide potential leads that can be developed into pharmaceutical compounds for a wide range of medicinal applications. However, there are scattered scientific reports about the anticancer activities of these constituents. Harnessing such information could provide a database of bioactive pharmacopeia or targeted scaffolds for drug discovery. Therefore, this review presents an updated and comprehensive summary of the ethnomedicinal uses, phytochemistry, and the anticancer activities of the triterpenoids of Euphorbia species. Most of the reported triterpenoids in this review belong to tirucallane, cycloartanes, lupane, oleanane, ursane, and taraxane subclass. Their anticancer activities varied distinctly with the majority of them exhibiting significant cytotoxic and anticancer activities in vitro. It is, therefore, envisaged that the report on Euphorbia triterpenoids with interesting anticancer activities will form a database of potential leads or scaffolds that could be advanced into the clinical trials with regard to drug discovery.

scholarly journals Cocculus hirsutus (L.) W.Theob. (Menispermaceae): A Review on Traditional Uses, Phytochemistry and Pharmacological Activities

Medicines ◽  
2020 ◽  
Vol 7 (11) ◽  
pp. 69
Author(s):  
Rajan Logesh ◽  
Niranjan Das ◽  
Anjana Adhikari-Devkota ◽  
Hari Prasad Devkota
Keyword(s):  
Skin Diseases ◽  
Chemical Constituents ◽  
Scientific Information ◽  
Bibliographic Databases ◽  
Pharmacological Activities ◽  
Traditional Medicines ◽  
Plant Parts ◽  
Traditional Uses

Background:Cocculus hirsutus (L.) W.Theob. (Menispermaceae) is a perennial climber distributed mostly in tropical and subtropical areas. The main aim of this article is to collect and analyze the scientific information related to traditional uses, bioactive chemical constituents and pharmacological activities. Methods: Scientific information on C. hirsutus was retrieved from the online bibliographic databases (e.g. MEDLINE/PubMed, SciFinder, Web of Science, Google Scholar and Scopus). Information regarding traditional uses was also acquired from secondary resources including books and proceedings. Results: Different plant parts of C. hirsutus were reported to be used for the treatment of fever, skin diseases, stomach disorders and urinary diseases. Alkaloids such as jasminitine, hirsutine, cohirsitine and their derivatives along with a few flavonoids, triterpene derivatives and volatile compounds were reported from whole plant or different plant parts. Extracts were evaluated for their antimicrobial, antidiabetic, immunomodulatory and hepatoprotective activities among others. Conclusion: Although widely used in traditional medicines, only a few studies have been performed related to chemical constituents. Most of the biological activity evaluations were carried out using in vitro evaluation methods and only a few studies were carried out in animal models. In the future, properly designed in vivo and clinical studies are necessary to evaluate the pharmacological activities of C. hirsutus along with bioassay-guided studies to isolate and identify the active constituents.

scholarly journals Nonvolatile Chemical Constituents from the Leaves of Ligusticopsis wallichiana (DC.) Pimenov & Kljuykov and Their Free Radical-Scavenging Activity

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Hari Prasad Devkota ◽  
Bibek Adhikari ◽  
Takashi Watanabe ◽  
Shoji Yahara
Keyword(s):  
Free Radical ◽  
Chemical Constituents ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Free Radical Scavenging Activity ◽  
Scavenging Activity ◽  
Traditional Medicines ◽  
Plant Parts ◽  
Major Chemical

Different plant parts of Ligusticopsis wallichiana (family: Apiaceae) are widely used as traditional medicines. Although many volatile constituents are already identified from the leaves of L. wallichiana, there is no detailed report on the nonvolatile constituents. In the present study, we aimed to isolate and identify the major chemical constituents from the leaves. Bhutkesoside A (1), falcarindiol (2), ferulic acid (3), cnidioside A (4), quercetin 3-O-β-D-glucopyranoside (5), rutin (6), 4′-O-methylquercetin 3-O-β-D-glucopyranoside (7), scopoletin (8), umbelliferone (9), eugenol 4-O-β-D-glucopyranoside (10) and pumilaside A (11) were isolated from the 70% MeOH extract. The structures of isolated compounds were elucidated on the basis of 1H- and 13C-NMR spectroscopic data. Compounds 4–11 are reported for the first time from L. wallichiana. Compounds 5 and 6 showed potent free radical-scavenging activity.

scholarly journals A Synthesis and Review of Medicinal Uses, Phytochemistry and Pharmacological Properties of Cissampelos mucronata A. Rich. (Menispermaceae)

2020 ◽  
Vol 10 (5) ◽  
pp. 213-222
Author(s):  
Alfred Maroyi
Keyword(s):  
Pharmacological Properties ◽  
Scientific Publications ◽  
Medicinal Uses ◽  
Sexually Transmitted ◽  
Respiratory Problems ◽  
Traditional Medicines ◽  
Plant Parts ◽  
Phytochemical Compounds ◽  
Cytotoxicity Activities ◽  
The University

Cissampelos mucronata A. Rich. is a perennial climber widely used as traditional medicine in tropical Africa. This study is aimed at providing a critical review of medicinal uses, phytochemical and pharmacological properties of C. mucronata. Documented information on medicinal uses, phytochemical and pharmacological properties of C. mucronata was collected from several online sources such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as book chapters, books, journal articles and scientific publications obtained from the University library. The articles published between 1962 and 2020 were used in this study. This study revealed that leaves, rhizome, roots and stems, and whole plant parts of C. mucronata are mainly used as traditional medicines for sexually transmitted infections, fever, swellings, headache, respiratory problems, snakebite, malaria, pregnancy problems and gastro-intestinal problems. Phytochemical compounds identified from the species include alkaloids, anthraquinones, flavonoids, glycerine, glycosides, phenolics, reducing sugars, resin, saponins, steroids, tannins and triterpenes. Pharmacological research revealed that C. mucronata extracts and alkaloids isolated from the species have antibacterial, anti-mycobacterial, antifungal, antiplasmodial, antitrypanosomal, anti-ulcer, anti-androgenic, anti-steroidogenic, enzyme tyrosine kinase p56 inhibitory, hypoglycemic, larvicidal, molluscicidal, sedative, tocolytic, uterine relaxant and cytotoxicity activities. There is need for extensive toxicological evaluations of crude extracts and compounds isolated from the species since C. mucronata contains potentially toxic compounds

scholarly journals Genus Stachys: A Review of Traditional Uses, Phytochemistry and Bioactivity

Medicines ◽  
2020 ◽  
Vol 7 (10) ◽  
pp. 63
Author(s):  
Ekaterina-Michaela Tomou ◽  
Christina Barda ◽  
Helen Skaltsa
Keyword(s):  
Biological Activities ◽  
Chemical Constituents ◽  
Present Review ◽  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Traditional Medicines ◽  
Traditional Uses ◽  
Perennial Herbs ◽  
New Research ◽  
Phytochemical Profiles

Background: The genus Stachys L. (Lamiaceae) includes about 300 species as annual or perennial herbs or small shrubs, spread in temperate regions of Mediterranean, Asia, America and southern Africa. Several species of this genus are extensively used in various traditional medicines. They are consumed as herbal preparations for the treatment of stress, skin inflammations, gastrointestinal disorders, asthma and genital tumors. Previous studies have investigated the chemical constituents and the biological activities of these species. Thus, the present review compiles literature data on ethnomedicine, phytochemistry, pharmacological activities, clinical studies and the toxicity of genus Stachys. Methods: Comprehensive research of previously published literature was performed for studies on the traditional uses, bioactive compounds and pharmacological properties of the genus Stachys, using databases with different key search words. Results: This survey documented 60 Stachys species and 10 subspecies for their phytochemical profiles, including 254 chemical compounds and reported 19 species and 4 subspecies for their pharmacological properties. Furthermore, 25 species and 6 subspecies were found for their traditional uses. Conclusions: The present review highlights that Stachys spp. consist an important source of bioactive phytochemicals and exemplifies the uncharted territory of this genus for new research studies.

scholarly journals A REVIEW ON PHARMACOLOGICAL AND PHYTOCHEMICAL PROFILE OF KHATMI (ALTHAEA OFFICINALIS LINN.): AN IMPORTANT MUCILAGINOUS PLANT AND ITS UTILIZATION IN UNANI SYSTEM OF MEDICINE

2021 ◽  
Vol 12 (3) ◽  
pp. 63-72
Author(s):  
Mazhar Husain ◽  
M Zaigham ◽  
Hamiduddin . ◽  
Abdul Wadud ◽  
Mohd Akhtar Ali
Keyword(s):  
Chemical Constituents ◽  
Therapeutic Tool ◽  
Pharmacological Activities ◽  
Unani Medicine ◽  
Traditional Medicines ◽  
Plant Parts ◽  
Inflammatory Conditions ◽  
Whole Plant ◽  
Mucous Membranes ◽  
Phytochemical Profile

Traditional medicines / drugs are helpful for management of life style disorders and chronic and acute diseases. Khatmi (Althea officinalis Linn.) is a one of the commonly used drugs that has potential for management of many diseases. The meaning of Khatmi (Marshmallow) is Kaseer-al-manafe (Multi actions) in Unani literature. Roots, flowers and seeds of Khatmi are used as a medicament. According to Unani texts the main actions of Khatmi are demulcent, expectorant, defragment, concoctive, astringent, detergent and repellent. It is also used as part of many traditional recipes. Analgesic, emollient, antitussive and diuretic activity are the most ethnobotanical and traditional medicine considerations; also used in Unani medicine for the treatment of the different inflammatory conditions e.g., metritis (Warme reham), enteritis (Warme amaa), mastitis (Warme pistan), arthritis (Waja ul mafasil) etc. Alkaloids, terpenoids, tannins, Flavonoids, Polysaccharides, Phytosterols, Fatty acids, Mucilages, Hydroxybenzoic acid etc. are its main Chemical constituents. The whole plant parts yields mucilage in decoction and infusions, which is very useful in case of several ailments of mucous membranes. The scientifically proven / reported pharmacological activities are antitussive, antimicrobial, immunomodulatory, UV exposure protective, anti-inflammatory, immune stimulating, antioxidant, antifungal, hepatoprotective, ulcer protective etc. These all findings reveal immense utility of Khatmi and scope for developing as a potent therapeutic tool particularly in contemporary lifestyle and also in immune susceptible diseases which is an emerging concern.

Ethnomedicinal uses, Phytochemistry and Pharmacological Aspects of the Genus Berberis Linn: A Comprehensive Review

2020 ◽  
Vol 23 ◽  
Author(s):  
Roohi Mohi-ud-din ◽  
Reyaz Hassan Mir ◽  
Prince Ahad Mir ◽  
Saeema Farooq ◽  
Syed Naiem Raza ◽  
...  
Keyword(s):  
Chemical Constituents ◽  
Pharmacological Activities ◽  
Traditional Use ◽  
Comprehensive Review ◽  
Wide Range ◽  
Anti Cancer ◽  
Comprehensive Survey ◽  
Ethnomedicinal Uses

Background: Genus Berberis (family Berberidaceae), which contains about 650 species and 17 genera worldwide, has been used in folklore and various traditional medicine systems. Berberis Linn. is the most established group among genera with around 450-500 species across the world. This comprehensive review will not only help researchers for further evaluation but also provide substantial information for future exploitation of species to develop novel herbal formulations. Objective: The present review is focussed to summarize and collect the updated review of information of Genus Berberis species reported to date regarding their ethnomedicinal information, chemical constituents, traditional/folklore use, and reported pharmacological activities on more than 40 species of Berberis. Conclusion: A comprehensive survey of the literature reveals that various species of the genus possess various phytoconstituents mainly alkaloids, flavonoid based compounds isolated from different parts of a plant with a wide range of pharmacological activities. So far, many pharmacological activities like anti-cancer, anti-hyperlipidemic, hepatoprotective, immunomodulatory, anti-inflammatory both in vitro & in vivo and clinical study of different extracts/isolated compounds of different species of Berberis have been reported, proving their importance as a medicinal plant and claiming their traditional use.

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